564 16 2803 2 10127 document 2803 Appendix File S1.xlsx application/vnd.openxmlformats-officedocument.spreadsheetml.sheet 8aca9cb0c7a12fd6e62c20dc56fcf55e MD5 37164 2026-07-13 12:15:59 https://bordar.bournemouth.ac.uk/564/1/Appendix%20File%20S1.xlsx 564 1 1 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet spreadsheet An anonymised isolate-level metadata table; raw AST measurements and susceptibility interpretations; sequence type, K/O locus, AMR, virulence and plasmid-typing results; assembly quality statistics; pairwise SNP matrix; phylogenetic alignment and Newick t en public cc_by_nd_4
Appendix File S1.xlsx
full_archive archive 12277 disk0/00/00/05/64 2026-07-31 15:31:26 2026-07-31 15:31:55 2026-07-31 15:31:26 data_collection show 1 Fordham Stephen sfordham@bournemouth.ac.uk Fordham Stephen i7643648@bournemouth.ac.uk Bioinformatic analyses of ST628 Klebsiella pneumoniae strains recovered from a nosocomial outbreak at University Hospitals Dorset: Appendix File S1 pub Klebsiella pneumoniae; antimicrobial resistance; plasmid genomics; genomic epidemiology; nosocomial outbreak. Appendix File S1. Isolate metadata and plasmid-associated antimicrobial resistance profiles of Klebsiella pneumoniae strains recovered during the University Hospitals Dorset outbreak. The file contains isolate-level epidemiological and genomic information, including isolate identifiers, collection dates, hospital departments, specimen sources, sequence types, phenotypic antimicrobial-susceptibility classifications, plasmid carriage, and plasmid-encoded antimicrobial resistance genes. It documents the distribution of the outbreak-associated IncFIB(K) multidrug-resistance plasmid and its resistance determinants, including blaCTX-M-15, blaOXA-1, blaTEM-1B, aac(3)-IIe, aac(6′)-Ib-cr, strA, strB, dfrA14, qnrB1, sul2, and tet(A), among the sequenced isolates. 2024-04-28 published MDPI https://www.mdpi.com/2076-2607/12/5/883 10.18746/bmth.data.00000564 Genomic epidemiology / nosocomial outbreak investigation The authors: Stephen Mark Edward Fordham, Francis Drobniewski, Magdalena Barrow, Melissa Hutchings, Kate Crowther, Denise Richards, Paul Bolton, Anna Mantzouratou and Elizabeth Sheridan. bordar@bournemouth.ac.uk Fordham Stephen i7643648@bournemouth.ac.uk Pfizer Global Medical Grants 68198087 Data were collected from 65 archived Klebsiella pneumoniae isolates retained during the University Hospitals Dorset outbreak investigation. For each isolate, non-identifiable metadata—including collection date, hospital department and specimen source—were collated from outbreak records. Species identity was confirmed by MALDI-TOF MS, and phenotypic antimicrobial susceptibility was determined by Kirby–Bauer disc diffusion against 11 antibiotics using EUCAST breakpoints. Isolates underwent Oxford Nanopore whole-genome sequencing, followed by genome assembly and in-silico identification of sequence type, antimicrobial-resistance genes and plasmid replicons. The resulting isolate metadata, resistance classifications and plasmid-associated resistance genotypes were compiled in Appendix File S1. 2017 2024