143 19 361 2 1511 document 361 Data Balaguer-Ballester et al Plos Comput Biol.zip application/zip a964d86c3e544db78ead36c05ebfc30f MD5 1642884171 2020-12-02 10:40:54 https://bordar.bournemouth.ac.uk/143/1/Data%20Balaguer-Ballester%20et%20al%20%20Plos%20Comput%20%20Biol.zip 143 1 1 application/zip archive en public cc_by_nd_4

Data Balaguer-Ballester et al Plos Comput Biol.zip

full_archive archive 1049 disk0/00/00/01/43 2020-12-09 11:10:30 2020-12-15 12:27:05 2020-12-09 11:10:30 data_collection 127 show 1 Balaguer-Ballester Emili eb-ballester@bournemouth.ac.uk Nogueira Ramon Abofalia Juan Moreno-Bote Ruben Sanchez-Vives Maria Victoria Institute for Biomedical Research August Pi i Sunyer (IDIBAPS , Barcelona Clinic Hospital, University of Barcelona) pub facsci Correlations, Higher order correlations, Kernels, Orbitofrontal Cortex, Interval Discrimination This curated dataset corresponds to the reference: Balaguer-Ballester, E., Nogueira, R., Abolafia, J.M., Moreno-Bote, R. Sanchez-Vives, M.V., 2020. Representation of Foreseeable Choice Outcomes in Orbitofrontal Cortex Triplet-wise Interactions. PLos Computational Biology. In short, the experiment consist of an interval discrimination task in rodent. The animal had to access the central socket in order to trigger a sequence of two 50 ms pure tones separated by either a short or a long inter-tone interval; by nose-poking either the left socket (for short ITI) or the right socket (for long ITI) to successfully retrieve the reward. After an incorrect trial, the previous ITI was repeated. Otherwise, the ITI was randomly drawn from a distribution of values which grade the difficulty of the task. The dataset consist of the stimulus characteristics, the behavioral responses and in vivo neuronal recordings in rodent Orbitofrontal Cortex. (see details below and in the paper). Please find specific "Readme.txt" files inside the folders with an explanation of the data format. 2020-06-02 published Bournemouth University 10.18746/bmth.data.00000143 neuroscience bordar@bournemouth.ac.uk Dr Balaguer-Ballester Emili eb-ballester@bournemouth.ac.uk pub https://doi.org/10.1371/journal.pcbi.1007862 DOI pub PLOS Computational Biology ds_other https://zenodo.org/record/4307741#.X9DZJ2j7SUk DOI https://zenodo.org/record/4307741#.X9DZJ2j7SUk pub Zenodo ds_other https://zenodo.org/record/4307748#.X9DZdWj7SUk DOI https://zenodo.org/record/4307748#.X9DZdWj7SUk pub Zenodo Data processing and formatting for this study was carried out in Bournemouth University, Bournemouth, Dorset, UK Async-Prop, Bournemouth University-IDIBAPS, RED11549, Partnering Project of the HBP SP3 (EU 667 H2020 Research and Innovation Programme) to Emili Balaguer-Ballester EU H2020 Research and Innovation Programme under Grant Agreement 665 No. 785907 (HBP SGA2), BFU2017-85048-R Spanish Ministry of Science to Maria Victoria Sanchez-Vives RED11549 Data were obtained from three Wistar rats (250 - 350 g) that were chronically implanted (when the psychometric curve reached the 70% in the task outlined below) with tetrodes in their lateral orbitofrontal (lOFC) cortex (see paper for more details). We recorded n = 137 single-units and ensembles from three animals. In this study, we specifically focus on ensembles containing a minimum of three units (82 units in total), and their corresponding local field potential (LFP). The LFP was downsampled to 250 Hz to filter out the typical spiking activity component. In addition, we recorded a subset of such same ensembles in which animals were passively exposed to the same stimuli, but in which rewards were not provided. For more details on the data please refer to the "Readme.txt" dedicated files in the folders. Experiment were carried out in Barcelona, Spain. The project was approved by the animal Ethics Committee of the University of Barcelona. All procedures were performed in compliance with protocols approved by the Animal Care and Use Committee of Autonomous University of Barcelona (CEEAH number 3866), with authorization from Department of Environment of the Generalitat de Catalunya, and with guidelines approved by the EU Council Directive for the care and use of laboratory animals (2010/63/EU). The authors confirm that all data underlying the findings are fully available without restriction. Electrophysiological data underlying the results presented in the study is publicly available from the authors under the terms of the Creative Commons license (https://creativecommons.org/licenses/by/4.0) 2014