Check,Reference,Publication.year,Paper,Fish,Fish.Species,Fish.Family,Habitat,Environment,Temperature.model,Fishbase.page,Thermal.minimum,Thermal.max,Thermal.range,Thermal.tolerance,Fish.details,Fish.age,Fish.sex,Study.type,Control.temp,Thermal.D.control,Test.temp,Thermal.D.test,D.Test.temp,Test.Cont.D,Test.D.Tmin,Test.D.Tmax,Test.D.min,Exposure.exp.temp,Exp.days,Exp.notes,Method,Specific.method,Immune.cells.studied,Category.Studied,Studied,Fold.change,Direction.change,Outlier.check,Challenge.category,Challenge,Pathogen.challenge,Author.country,Fish.source,Average.N.group,Experiment.repeated,ID,Temperature.exposure,Immunogen.exposure,Imm.duration.days,Imm.notes,Gene.category.1,Gene.category.2,Gene.category.3,BLAST.notes,David.Zebra,Ensembl.Zebra,Ensembl.Rainbow,Fish.identifier,Human.homolog,PANTHER.protein,CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM,SIGNALING_BY_INTERLEUKINS,INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING,IMMUNE_SYSTEM,INNATE_IMMUNE_SYSTEM,SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES,INTERFERON_ALPHA_BETA_SIGNALING,INFECTIOUS_DISEASE,SARS_COV_INFECTIONS,TOLL_LIKE_RECEPTOR_CASCADES,SARS_COV_2_HOST_INTERACTIONS,INTERLEUKIN_10_SIGNALING,SARS_COV_2_INFECTION,INTERFERON_SIGNALING,DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA,INTERLEUKIN_6_SIGNALING,INTERLEUKIN_6_FAMILY_SIGNALING,TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE,DISEASES_OF_IMMUNE_SYSTEM,INTERLEUKIN_1_FAMILY_SIGNALING,TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE,INTERFERON_GAMMA_SIGNALING,SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES,GROWTH_HORMONE_RECEPTOR_SIGNALING,REGULATION_OF_IFNA_IFNB_SIGNALING,PYROPTOSIS,POTENTIAL_THERAPEUTICS_FOR_SARS,TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR,TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING,TRAF6_MEDIATED_IRF7_ACTIVATION,REGULATION_OF_IFNG_SIGNALING,INTERLEUKIN_12_FAMILY_SIGNALING,CELLULAR_RESPONSES_TO_STIMULI,TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY,REGULATED_NECROSIS,DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES,IRAK4_DEFICIENCY_TLR2_4,ANTIMICROBIAL_PEPTIDES,MYD88_INDEPENDENT_TLR4_CASCADE,NEUTROPHIL_DEGRANULATION,INTERLEUKIN_1_SIGNALING,PROGRAMMED_CELL_DEATH,MAPK1_ERK2_ACTIVATION,INACTIVATION_OF_CSF3_G_CSF_SIGNALING,PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION,INTERLEUKIN_21_SIGNALING,SIGNALING_BY_CSF3_G_CSF,DEFENSINS,SARS_COV_1_HOST_INTERACTIONS,SARS_COV_1_INFECTION,CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA,TICAM1_DEPENDENT_ACTIVATION_OF_IRF3_IRF7,CELLULAR_RESPONSE_TO_CHEMICAL_STRESS,NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING,ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES,GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION,OVARIAN_TUMOR_DOMAIN_PROTEASES,TOLL_LIKE_RECEPTOR_4_TLR4_CASCADE,ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON,SIGNALING_BY_SCF_KIT,INTERLEUKIN_2_FAMILY_SIGNALING,ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES,INTERLEUKIN_12_SIGNALING,BETA_DEFENSINS,REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND,ZBP1_DAI_MEDIATED_INDUCTION_OF_TYPE_I_IFNS,RAF_INDEPENDENT_MAPK1_3_ACTIVATION,ALTERNATIVE_COMPLEMENT_ACTIVATION,IRF3_MEDIATED_INDUCTION_OF_TYPE_I_IFN,TRAF6_MEDIATED_NF_KB_ACTIVATION,CELLULAR_RESPONSE_TO_HEAT_STRESS,ACYL_CHAIN_REMODELING_OF_CL,INTERLEUKIN_20_FAMILY_SIGNALING,HEMOSTASIS,LEISHMANIA_INFECTION,INFECTION_WITH_MYCOBACTERIUM_TUBERCULOSIS,ANTIGEN_PROCESSING_CROSS_PRESENTATION,ATTENUATION_PHASE,DEX_H_BOX_HELICASES_ACTIVATE_TYPE_I_IFN_AND_INFLAMMATORY_CYTOKINES_PRODUCTION,STING_MEDIATED_INDUCTION_OF_HOST_IMMUNE_RESPONSES,SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP,FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES,RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES,INTERLEUKIN_1_PROCESSING,INTERLEUKIN_18_SIGNALING,INTERLEUKIN_17_SIGNALING,SYNTHESIS_OF_5_EICOSATETRAENOIC_ACIDS,MAPK3_ERK1_ACTIVATION,INTERLEUKIN_9_SIGNALING,CD163_MEDIATING_AN_ANTI_INFLAMMATORY_RESPONSE,ADAPTIVE_IMMUNE_SYSTEM,INTERLEUKIN_7_SIGNALING,STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING,HSF1_DEPENDENT_TRANSACTIVATION,SIGNALING_BY_LEPTIN,INTERLEUKIN_15_SIGNALING,INTERLEUKIN_27_SIGNALING,REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE,INTERLEUKIN_35_SIGNALLING,SIGNALING_BY_PDGFRA_TRANSMEMBRANE_JUXTAMEMBRANE_AND_KINASE_DOMAIN_MUTANTS,TAK1_DEPENDENT_IKK_AND_NF_KAPPA_B_ACTIVATION,NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE,REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA,ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING,NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10,NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS,DEUBIQUITINATION,CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION,HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND,RIP_MEDIATED_NFKB_ACTIVATION_VIA_ZBP1,G_ALPHA_I_SIGNALLING_EVENTS,SIGNALING_BY_PTK6,INTRINSIC_PATHWAY_FOR_APOPTOSIS,SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS,NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER,CHEMOKINE_RECEPTORS_BIND_CHEMOKINES,ARACHIDONIC_ACID_METABOLISM,SIGNALING_BY_PDGFR_IN_DISEASE,SIGNALING_BY_KIT_IN_DISEASE,PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION,NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS,CYTOPROTECTION_BY_HMOX1,JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1,CHAPERONE_MEDIATED_AUTOPHAGY,SIGNALING_BY_RECEPTOR_TYROSINE_KINASES,FOXO_MEDIATED_TRANSCRIPTION,RESPONSE_OF_MTB_TO_PHAGOCYTOSIS,ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION,ENDOSOMAL_VACUOLAR_PATHWAY,BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS,SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX,SYNTHESIS_OF_LIPOXINS_LX,IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS,FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION,THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS,TCR_SIGNALING,CELLULAR_SENESCENCE,CLEC7A_INFLAMMASOME_PATHWAY,INFLAMMASOMES,MYD88_MAL_TIRAP_CASCADE_INITIATED_ON_PLASMA_MEMBRANE,NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL,P75NTR_SIGNALS_VIA_NF_KB,REGULATED_PROTEOLYSIS_OF_P75NTR,THE_NLRP3_INFLAMMASOME,TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION,ZBP1_DAI_MEDIATED_INDUCTION_OF_TYPE_I_IFNS.1,TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT,TICAM1_TRAF6_DEPENDENT_INDUCTION_OF_TAK1_COMPLEX,IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1,NOD1_2_SIGNALING_PATHWAY,P75NTR_RECRUITS_SIGNALLING_COMPLEXES,TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,5-Lox ,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,1,Acute,NA,NA,,5-Lox ,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,alox5a,Unknown,alox5a,ALOX5,oxygenase,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,5-Lox ,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,2,Acute,NA,NA,,5-Lox ,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,alox5a,Unknown,alox5a,ALOX5,oxygenase,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,5-Lox ,0.6,Decrease,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,3,Acute,NA,NA,,5-Lox ,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,alox5a,Unknown,alox5a,ALOX5,oxygenase,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,5-Lox ,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,4,Acute,NA,NA,,5-Lox ,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,alox5a,Unknown,alox5a,ALOX5,oxygenase,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,COX2,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,5,Acute,NA,NA,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,COX2,1.2,Increase,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,6,Acute,NA,NA,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,COX2,1.3,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,7,Acute,NA,NA,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,COX2,0.8,Decrease,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,8,Acute,NA,NA,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Flap,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,9,Acute,NA,NA,,Flap,Eicosanoid sythesis,Eicosanoid synthesis,(5-lipoxygenase-activating protein (from the paper)),unknown,unknown,unknown,alox5ap,ALOX5AP,transferase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Flap,0.8,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,10,Acute,NA,NA,,Flap,Eicosanoid sythesis,Eicosanoid synthesis,(5-lipoxygenase-activating protein (from the paper)),unknown,unknown,unknown,alox5ap,ALOX5AP,transferase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Flap,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,11,Acute,NA,NA,,Flap,Eicosanoid sythesis,Eicosanoid synthesis,(5-lipoxygenase-activating protein (from the paper)),unknown,unknown,unknown,alox5ap,ALOX5AP,transferase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Flap,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,12,Acute,NA,NA,,Flap,Eicosanoid sythesis,Eicosanoid synthesis,(5-lipoxygenase-activating protein (from the paper)),unknown,unknown,unknown,alox5ap,ALOX5AP,transferase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Lpl,0.8,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,13,Acute,NA,NA,,Lpl,Lipase,Lipase,,Unknown,lpl,Unknown,lpl,LPL,Lipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Lpl,1.2,Increase,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,14,Acute,NA,NA,,Lpl,Lipase,Lipase,,Unknown,lpl,Unknown,lpl,LPL,Lipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Lpl,1.3,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,15,Acute,NA,NA,,Lpl,Lipase,Lipase,,Unknown,lpl,Unknown,lpl,LPL,Lipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,Lpl,1.2,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,16,Acute,NA,NA,,Lpl,Lipase,Lipase,,Unknown,lpl,Unknown,lpl,LPL,Lipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1a,1.2,Increase,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,17,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,(ATP1A1A according to link in paper),unknown,unknown,unknown,atp1a1a,ATP1A1,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1a,0.7,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,18,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,(ATP1A1A according to link in paper),unknown,unknown,unknown,atp1a1a,ATP1A1,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1a,5,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,19,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,(ATP1A1A according to link in paper),unknown,unknown,unknown,atp1a1a,ATP1A1,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1a,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,20,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,(ATP1A1A according to link in paper),unknown,unknown,unknown,atp1a1a,ATP1A1,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1b,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,21,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,,unknown,unknown,unknown,atp1a1b,ATP1A2,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1b,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,22,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,,unknown,unknown,unknown,atp1a1b,ATP1A2,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1b,0.8,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,23,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,,unknown,unknown,unknown,atp1a1b,ATP1A2,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,NKAa1b,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,24,Acute,NA,NA,,ATPase,Sodium/potassium transport,Sodium/potassium transport,,unknown,unknown,unknown,atp1a1b,ATP1A2,unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g4,1,Same,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,25,Acute,NA,NA,,PLA2g4,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,pla2g4aa,Unknown,pla2g4aa,PLA2G4A,phospholipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g4,1.4,Increase,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,26,Acute,NA,NA,,PLA2g4,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,pla2g4aa,Unknown,pla2g4aa,PLA2G4A,phospholipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g4,0.8,Decrease,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,27,Acute,NA,NA,,PLA2g4,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,pla2g4aa,Unknown,pla2g4aa,PLA2G4A,phospholipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g4,1,Same,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,28,Acute,NA,NA,,PLA2g4,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,pla2g4aa,Unknown,pla2g4aa,PLA2G4A,phospholipase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g6,0.6,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,29,Acute,NA,NA,,PLA2g6,Eicosanoid sythesis,Eicosanoid synthesis,,PLA2G6,pla2g6,Unknown,pla2g6,PLA2G6,phospholipase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g6,0.6,Decrease,FALSE,Other,Diet (but comparing control diet with control diet in every case),N,Norway,Wild,6,not stated,30,Acute,NA,NA,,PLA2g6,Eicosanoid sythesis,Eicosanoid synthesis,,PLA2G6,pla2g6,Unknown,pla2g6,PLA2G6,phospholipase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,8,Within,-4,Decrease,6,-1,0,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g6,1.8,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,31,Acute,NA,NA,,PLA2g6,Eicosanoid sythesis,Eicosanoid synthesis,,PLA2G6,pla2g6,Unknown,pla2g6,PLA2G6,phospholipase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Miao, L.H., Remø, S.C., Espe, M., Philip, A.J.P., Hamre, K., Fjelldal, P.G., Skjærven, K., Holen, E., Vikeså, V. and Sissener, N.H., 2022. Dietary plant oil supplemented with arachidonic acid and eicosapentaenoic acid affects the fatty acid composition and eicosanoid metabolism of Atlantic salmon (Salmo salar L.) during smoltification. Fish & Shellfish Immunology, 123, pp.194-206.",2022,1,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp ,12,Above,16,Above,4,Increase,14,7,7,24 hours ,1,Time sample taken post temp first changed,Molecular,qPCR ,Gill tissues ,Gene,PLA2g6,1.2,Increase,FALSE,Other,Modified oil diet (comparing fish having the same diet),N,Norway,Wild,6,not stated,32,Acute,NA,NA,,PLA2g6,Eicosanoid sythesis,Eicosanoid synthesis,,PLA2G6,pla2g6,Unknown,pla2g6,PLA2G6,phospholipase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,camp-b,1,Same,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,33,Chronic,Acute,0.5,,Camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,camp-b,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,camp-b,1,Same,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,34,Chronic,Acute,0.5,,Camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,camp-b,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CCL19b,1,Same,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,35,Chronic,Acute,0.5,,IL-19,Chemokine,B cell response,,CCL19B,ccl19b,Unknown,ccl19b,CCL19,cytokine,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CCL19b,1,Same,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,36,Chronic,Acute,0.5,,IL-19,Chemokine,B cell response,,CCL19B,ccl19b,Unknown,ccl19b,CCL19,cytokine,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,COX2,0.1,Decrease,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,37,Chronic,Acute,0.5,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,COX2,0.05,Decrease,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,38,Chronic,Acute,0.5,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CXCL8,0.8,Decrease,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,39,Chronic,Acute,0.5,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,chemokine,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CXCL8,0.5,Decrease,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,40,Chronic,Acute,0.5,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,chemokine,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,hamp-a,1,Same,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,41,Chronic,Acute,0.5,,hamp-a,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,hamp-a,2,Increase,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,42,Chronic,Acute,0.5,,hamp-a,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 1 day post pI:C if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IFN-g,0.4,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,43,Chronic,Acute,1,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then 1 day post pI:C if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IFN-g,0.3,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,44,Chronic,Acute,1,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR ,Head kidney,Gene,IL-1b,0.5,Decrease,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,45,Chronic,Acute,0.5,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,0.3,Decrease,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,46,Chronic,Acute,0.5,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,irf7-b,0.3,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,47,Chronic,Acute,1,,irf7,Anti-viral signalling,PRR,,Unknown,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,irf7-b,0.25,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,48,Chronic,Acute,1,,irf7,Anti-viral signalling,PRR,,Unknown,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,isg15a,0.2,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,49,Chronic,Acute,1,,isg15,RLR pathway,PRR,,Unknown,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,isg15a,0.06,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,50,Chronic,Acute,1,,isg15,RLR pathway,PRR,,Unknown,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,lgp2,0.3,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,51,Chronic,Acute,1,,lgp2,RLR pathway,PRR,,Unknown,dhx58,Unknown,dhx58,DHX58,Unknown,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,lgp2,0.1,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,52,Chronic,Acute,1,,lgp2,RLR pathway,PRR,,Unknown,dhx58,Unknown,dhx58,DHX58,Unknown,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,Mx-b,0.7,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,53,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxb,Unknown,mxb,MX2,membrane traffice protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,Mx-b,0.5,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,54,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxb,Unknown,mxb,MX2,membrane traffice protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,rsad-2,0.1,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,55,Chronic,Acute,1,,rsad,RLR pathway,PRR,,Unknown,rsad2,Unknown,rsad2,RSAD2,Unknown,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,rsad-2b,0.2,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,56,Chronic,Acute,1,,rsad,RLR pathway,PRR,,Unknown,rsad2,Unknown,rsad2,RSAD2,Unknown,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,saa5,1,Same,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,57,Chronic,Acute,0.5,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,saa5,1,Same,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,58,Chronic,Acute,0.5,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,Stat1b,0.5,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,59,Chronic,Acute,1,,STAT,Cytokine signalling,Cytokine signalling,,STAT1B,stat1b,Unknown,stat1b,STAT1,DNA-binding transcription factor,1,1,1,0,0,1,1,1,1,0,1,0,1,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,stlr5-a,0.8,Decrease,FALSE,Other,Vaccine response at 12 hours,N,Canada ,Aquaculture,4,4,60,Chronic,Acute,0.5,,stlr5-a,TLR pathway,PRR,,Unknown,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 0.5 day post vaccine if given ",29.5,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,stlr5-a,1,Same,FALSE,Other,Vaccine response at 12 hours; second expt with different additional parameters,N,Canada ,Aquaculture,4,4,61,Chronic,Acute,0.5,,stlr5-a,TLR pathway,PRR,,Unknown,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TLR-7,0.5,Decrease,FALSE,Chemical,pI:C 24 hours,N,Canada ,Aquaculture,4,4,62,Chronic,Acute,1,,TLR-7,TLR pathway,PRR,,Unknown,tlr7,Unknown,tlr7,TLR7,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Sandrelli, R.M., Ellen de Fátima, C.P., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2022. Atlantic Salmon (Salmo salar) bacterial and viral innate immune responses are not impaired by florfenicol or tetracycline administration. Fish & Shellfish Immunology, 123, pp.298-313.",2022,2,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,Pre-moult ,Juvenile,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,"acclimated at temperature for 2 weeks, 15 days diet and then time point of 1 day post vaccine if given ",30,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TLR-7,0.25,Decrease,FALSE,Chemical,"pI:C 24 hours, second expt with additional parameters",N,Canada ,Aquaculture,4,4,63,Chronic,Acute,1,,TLR-7,TLR pathway,PRR,,Unknown,tlr7,Unknown,tlr7,TLR7,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,IFN-g,2,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,64,Acute,NA,NA,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,IL-10,2,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,65,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,IL-1b,2,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,66,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,IL-4/IL-13A,2,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,67,Acute,NA,NA,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,TGF-b,3,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,68,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Østevik, L., Stormoen, M., Evensen, Ø., Xu, C., Lie, K.I., Nødtvedt, A., Rodger, H., Skagøy, A., Manji, F. and Alarcón, M., 2022. Effects of thermal and mechanical delousing on gill health of farmed Atlantic salmon (Salmo salar L.). Aquaculture, 552, p.738019.",2022,3,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp,15,Above,31,Above,16,Increase,29,22,22,"20-30S, sampled 1-2 days later",1.5,Time sample taken post temp first changed,Molecular,qPCR,Gill tissues ,Gene,TNF-a,3,Increase,FALSE,NA,NA,N,Norway,Aquaculture,7,6,69,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,102 days,102,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,CD8a,2,Increase,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,70,Chronic,Chronic,92,"Moreover, the development time from chalimus to the adult stage increased from 18 days at 16°C to 49 days at 4°C",CD8,T cell,T cell response,,CD8A,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,35 days,35,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,CD8a,0.7,Decrease,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",12,71,Chronic,Chronic,25,,CD8,T cell,T cell response,,CD8A,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,102 days,102,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IgM-antigen specific,1.2,Increase,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",3,72,Chronic,Chronic,92,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,35 days,35,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IgM-antigen specific,1,Same,FALSE,Other,Lice - adult,N,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",13,73,Chronic,Chronic,25,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,102 days,102,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-10,2,Increase,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",4,74,Chronic,Chronic,92,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,35 days,35,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-10,1,Same,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",14,75,Chronic,Chronic,25,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-1b,2.5,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,76,Chronic,Chronic,70,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,22 days,22,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-1b,3,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",6,77,Chronic,Chronic,12,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,102 days,102,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-4,6,Increase,FALSE,Other,Lice adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,78,Chronic,Chronic,92,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days ,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-4,0.5,Decrease,FALSE,Other,Lice preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,79,Chronic,Chronic,70,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,22 days ,22,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-4,2,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",10,80,Chronic,Chronic,12,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,35 days,35,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-4,7,Increase,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",11,81,Chronic,Chronic,25,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days ,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-8,2,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,82,Chronic,Chronic,70,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,22 days ,22,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,IL-8,4,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",8,83,Chronic,Chronic,12,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,MMP-9,1,Same,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",5,84,Chronic,Chronic,70,,MMP-9,Tissue remodelling,Degradative enzyme,,Unknown,mmp9,Unknown,mmp9,MMP9,metalloprotease,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,17 days,17,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,MMP-9,0.5,Decrease,FALSE,Other,Lice - chalimus,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",15,85,Chronic,Chronic,7,,MMP-9,Tissue remodelling,Degradative enzyme,,Unknown,mmp9,Unknown,mmp9,MMP9,metalloprotease,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,22 days,22,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,MMP-9,2,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",16,86,Chronic,Chronic,12,,MMP-9,Tissue remodelling,Degradative enzyme,,Unknown,mmp9,Unknown,mmp9,MMP9,metalloprotease,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days ,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,SAA,0.5,Decrease,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,87,Chronic,Chronic,70,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,SAA,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,102 days ,102,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,SAA,4,Increase,FALSE,Other,Lice = adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,88,Chronic,Chronic,92,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,SAA,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,22 days ,22,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,SAA,4,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",9,89,Chronic,Chronic,12,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,SAA,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,4,Within,-4,Decrease,2,-5,0,80 days ,80,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,TNF-a,2,Increase,FALSE,Other,Lice - preadult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",2,90,Chronic,Chronic,70,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ugelvik, M.S., Mæhle, S. and Dalvin, S., 2022. Temperature affects settlement success of ectoparasitic salmon lice (Lepeophtheirus salmonis) and impacts the immune and stress response of Atlantic salmon (Salmo salar). Journal of Fish Diseases.",2022,4,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,adult ,Adult,Not stated,Exp ,8,Within,16,Above,8,Increase,14,7,7,35 days ,35,Time sample taken post temp first changed,Molecular,qPCR,Skin,Gene,TNF-a,7,Increase,FALSE,Other,Lice - adult,Y,Norway,Aquaculture,"4oC, 1008 lice/tank; 8oC, 672 lice/tank; 12oC, 525 lice/tank and 16oC, 462 lice/tank",7,91,Chronic,Chronic,25,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,92,Acute,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1.5,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,93,Acute,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,0.9,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,94,Chronic,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1.3,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,95,Chronic,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,96,Acute,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1.2,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,97,Acute,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,0.6,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,98,Chronic,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,CRH,1.7,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,99,Chronic,NA,NA,,CRH,Hormone,Hormone,,CRH,crha,Unknown,crha,CRH,peptide hormone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,100,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,2,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,101,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,102,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1.4,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,103,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1.6,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,104,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,2,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,105,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1.3,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,106,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,HSP70,1.3,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,107,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,0.5,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,108,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,1.5,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,109,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,0.9,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,110,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,0.8,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,111,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,0.6,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,112,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,2,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,113,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,3,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,114,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,1.3,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,115,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,116,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,2.5,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,117,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,0.3,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,118,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,0.9,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,119,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,1.2,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,120,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,0.9,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,121,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,0.5,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,122,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,123,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,124,Acute,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,3.5,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,125,Acute,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,0.4,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,126,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,127,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,128,Acute,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,0.5,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,129,Acute,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,0.6,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,130,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-6,0.9,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,131,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,132,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,0.8,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,133,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,0.7,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,134,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,135,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,136,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,0.4,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,137,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,0.3,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,138,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-8,0.9,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,139,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,140,Acute,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,0.6,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,141,Acute,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1.6,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,142,Chronic,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,143,Chronic,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,144,Acute,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,0.5,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,145,Acute,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1.7,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,146,Chronic,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TRAF6,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,147,Chronic,NA,NA,,TRAF6,T cell driver,T cell response,IRAF was incorrectly written,unknown,unknown,unknown,traf6,TRAF6,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,1,0,0,1,0,1,1,0,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,1,1,1,0,0,0,1,1,1,1,1,1
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,148,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1.5,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,149,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,150,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,151,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1.4,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,152,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1.4,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,153,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,0.8,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,154,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TGF-b1,1.3,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,155,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,1,Same,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,156,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,2 hours at 12C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,0.4,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,157,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,0.4,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,158,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,12,Within,-6,Decrease,3.4,-13,0,8 days at 12C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,1,Same,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,159,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,1.2,Increase,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,160,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,2hours at 24C,0.083,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,0.3,Decrease,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,161,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,0.4,Decrease,FALSE,Other,Separate study; bold,N,China ,Aquaculture,36,6,162,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhang, X., Yuan, M. and Lu, W., 2022. Individuality in flounder (Paralichthys olivaceus): Differential responses of immune–endocrine during temperature stress in head kidney. Aquaculture Research, 53(4), pp.1327-1336.",2021,5,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,adult ,Adult,F,Exp ,18,Within,24,Within,6,Increase,15.4,-1,0,8 days at 24C,8,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,1.4,Increase,FALSE,Other,Separate study; shy,N,China ,Aquaculture,36,6,163,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,15 days at 17C; comparing to time zero,15,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,CD4,3,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,164,Chronic,Chronic,15,,CD4,T cell,T cell response,,Unknown,cd4-1,Unknown,cd4-1,CD4,immunoglobulin receptor superfamily,1,1,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,15 days at 25C; comparing to time zero,15,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,CD4,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,165,Chronic,Chronic,15,,CD4,T cell,T cell response,,Unknown,cd4-1,Unknown,cd4-1,CD4,immunoglobulin receptor superfamily,1,1,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,16 days at 25C; comparing to time zero,16,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,CD8,4,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,166,Chronic,Chronic,16,,CD8,T cell,T cell response,,Unknown,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,16 days at 17C; comparing to time zero,16,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,CD8,4,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,167,Chronic,Chronic,16,,CD8,T cell,T cell response,,Unknown,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFN-g,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,168,Chronic,Chronic,7,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFN-g,10,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,169,Chronic,Chronic,7,secondary cahllenge,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFN-g,13,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,170,Chronic,Chronic,7,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFN-g,10,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,171,Chronic,Chronic,37,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFNI,7,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,172,Chronic,Chronic,7,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFNI,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,173,Chronic,Chronic,7,secondary cahllenge,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IFNI,6,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,174,Chronic,Chronic,7,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,IFNI,10,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,175,Chronic,Chronic,37,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,17 days at 17C; comparing to time zero,17,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IgM-antigen specific,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,176,Chronic,Chronic,17,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,17 days at 25C; comparing to time zero,17,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IgM-antigen specific,10,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,177,Chronic,Chronic,17,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IL-1b,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,178,Chronic,Chronic,7,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IL-1b,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,179,Chronic,Chronic,7,secondary cahllenge,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,IL-1b,7,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,180,Chronic,Chronic,7,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,IL-1b,18,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,181,Chronic,Chronic,7,secondary cahllenge,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,isg15,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,182,Chronic,Chronic,7,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,isg15,10,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,183,Chronic,Chronic,7,secondary cahllenge,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,isg15,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,184,Chronic,Chronic,7,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,isg15,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,185,Chronic,Chronic,7,secondary cahllenge,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,Mx,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,186,Chronic,Chronic,7,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,Mx,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,187,Chronic,Chronic,7,secondary cahllenge,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,Mx,5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,188,Chronic,Chronic,7,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,Mx,14,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,189,Chronic,Chronic,7,secondary cahllenge,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,10 days at 17C; compared with control,10,Time sample taken post temp first changed,Molecular,qPCR,Brain   ,Gene,NCCRP-1,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,190,Chronic,Chronic,10,,NCCRP-1,Cell proliferation,Cell proliferation,,Unknown,nccrp1,Unknown,nccrp1,NCCRP1,ubiquitin-protein ligase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,10 days at 25C; compared with control,10,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,NCCRP-1,1.4,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,191,Chronic,Chronic,10,,NCCRP-1,Cell proliferation,Cell proliferation,,Unknown,nccrp1,Unknown,nccrp1,NCCRP1,ubiquitin-protein ligase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,30 days at 17C; compare with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,SOCS1,3,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,192,Chronic,Chronic,30,,SOC,Negative cytokine signalling,Cytokine signalling,,Unknown,socs1a,Unknown,socs1a,SOCS1,kinase modulator,1,1,1,1,1,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,30 days at 25C; compared with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,SOCS1,4,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,193,Chronic,Chronic,30,,SOC,Negative cytokine signalling,Cytokine signalling,,Unknown,socs1a,Unknown,socs1a,SOCS1,kinase modulator,1,1,1,1,1,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,30 days at 17C; compare with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,SOCS3,3,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,194,Chronic,Chronic,30,,SOC,Negative cytokine signalling,Cytokine signalling,,Unknown,socs3a,Unknown,socs3a,SOCS3,kinase modulator,1,1,1,1,0,0,1,0,0,0,0,0,0,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,30 days at 25C; compared with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,SOCS3,3,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,195,Chronic,Chronic,30,,SOC,Negative cytokine signalling,Cytokine signalling,,Unknown,socs3a,Unknown,socs3a,SOCS3,kinase modulator,1,1,1,1,0,0,1,0,0,0,0,0,0,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,30 days at 17C; compare with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,STAT1 ,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,196,Chronic,Chronic,30,,STAT,Cytokine signalling,Cytokine signalling,,Unknown,stat1a,Unknown,stat1a,STAT1,DNA-binidng transcription factor,1,1,1,0,0,1,1,1,1,0,1,0,1,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,30 days at 25C; compared with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,STAT1 ,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,197,Chronic,Chronic,30,,STAT,Cytokine signalling,Cytokine signalling,,Unknown,stat1a,Unknown,stat1a,STAT1,DNA-binidng transcription factor,1,1,1,0,0,1,1,1,1,0,1,0,1,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,30 days at 17C; compare with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,STAT3,8,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,198,Chronic,Chronic,30,,STAT,Cytokine signalling,Cytokine signalling,,STAT3,stat3,Unknown,stat3,STAT3,DNA-binding transcription factor,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,1,1,0,1,1,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,1,1,1,0,0,1,1,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,30 days at 25C; compared with time zero,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,STAT3,4,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,199,Chronic,Chronic,30,,STAT,Cytokine signalling,Cytokine signalling,,STAT3,stat3,Unknown,stat3,STAT3,DNA-binding transcription factor,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,1,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,1,1,0,1,1,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,1,1,1,0,0,1,1,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,30 days at 17C; compared with control,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,TMEM-119,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,200,Chronic,Chronic,30,,TMEM-119,TLR pathway,PRR,,Unknown,tlr5b,Unknown,tlr5b,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,30 days at 25C; compared with control,30,Time sample taken post temp first changed,Molecular,qPCR,Brain  ,Gene,TMEM-119,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,201,Chronic,Chronic,30,,TMEM-119,TLR pathway,PRR,,Unknown,tlr5b,Unknown,tlr5b,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,17,Within,-4,Decrease,1.1,-7.1,0,7 days at 17C (this is the snapshot I'm using; peak),7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,TNF-a,2.5,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,202,Chronic,Chronic,7,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,"30 days at 17C, then 7 days at 25C",37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,TNF-a,2,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,203,Chronic,Chronic,7,secondary cahllenge,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,7 days at 25C,7,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,TNF-a,6,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,204,Chronic,Chronic,7,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Krishnan, R., Jang, Y.S., Kim, J.O. and Oh, M.J., 2021. Altered expression of immune factors in sevenband grouper, Hyporthodus septemfasciatus following nervous necrosis virus challenge at optimal and suboptimal temperatures. Fish & Shellfish Immunology, 119, pp.442-451.",2021,6,seven-band grouper (Hyporthodus septemfasciatus),Hyporthodus septemfasciatus,Epinephelidae,Marine,Tropical,Y,https://www.fishbase.se/summary/Hyporthodus-septemfasciatus.html,15.9,24.1,8.2,Narrow,Juvenile ,Juvenile,Not stated,Exp,21,Within,25,Above,4,Increase,9.1,0.9,0.9,37 days at 25C,37,Time sample taken post temp first changed,Molecular,qPCR,Brain,Gene,TNF-a,12,Increase,FALSE,Viral. Looks like viral challenge and temperature change at same time,Viral,Y,Korea ,Aquaculture,6,2,205,Chronic,Chronic,7,secondary cahllenge,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhao, Z., He, R., Chu, P., Cai, H., Shen, H., Zhao, Z., Feng, S., Cao, D., Liao, M., Gan, G. and Ye, H., 2021. YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus. Fish & Shellfish Immunology, 118, pp.72-84.",2021,7, Misgurnus anguillicaudatus,Misgurnus anguillicaudatus,Cobitidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Misgurnus-anguillicaudatus.html,5,25,20,Wide,Not stated,Not stated,Not stated,Exp,25,Within,15,Within,-10,Decrease,10,-10,0,two weeks ; CpG for 24 hours,15,Time sample taken post temp first changed,Molecular,qPCR ,Intestine,Gene,Hsc70,1,Same,FALSE,Chemical,CpG ODN,N,China ,Aquaculture,100,not stated ,206,Chronic,Acute,1,,Hsc70,Heat stress,Heat stress,,HSC70,hsc70,Unknown,hsc70,HSPA8,Hsp70 family chaperone,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhao, Z., He, R., Chu, P., Cai, H., Shen, H., Zhao, Z., Feng, S., Cao, D., Liao, M., Gan, G. and Ye, H., 2021. YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus. Fish & Shellfish Immunology, 118, pp.72-84.",2021,7, Misgurnus anguillicaudatus,Misgurnus anguillicaudatus,Cobitidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Misgurnus-anguillicaudatus.html,5,25,20,Wide,Not stated,Not stated,Not stated,Exp,25,Within,15,Within,-10,Decrease,10,-10,0,two weeks ; CpG for 24 hours,15,Time sample taken post temp first changed,Molecular,qPCR ,Intestine,Gene,IFN-g,1,Same,FALSE,Chemical,CpG ODN,N,China ,Aquaculture,100,not stated ,207,Chronic,Acute,1,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhao, Z., He, R., Chu, P., Cai, H., Shen, H., Zhao, Z., Feng, S., Cao, D., Liao, M., Gan, G. and Ye, H., 2021. YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus. Fish & Shellfish Immunology, 118, pp.72-84.",2021,7, Misgurnus anguillicaudatus,Misgurnus anguillicaudatus,Cobitidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Misgurnus-anguillicaudatus.html,5,25,20,Wide,Not stated,Not stated,Not stated,Exp,25,Within,15,Within,-10,Decrease,10,-10,0,two weeks ; CpG for 24 hours,15,Time sample taken post temp first changed,Molecular,qPCR ,Intestine,Gene,IL-1b,0.6,Decrease,FALSE,Chemical,CpG ODN,N,China ,Aquaculture,100,not stated ,208,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zhao, Z., He, R., Chu, P., Cai, H., Shen, H., Zhao, Z., Feng, S., Cao, D., Liao, M., Gan, G. and Ye, H., 2021. YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus. Fish & Shellfish Immunology, 118, pp.72-84.",2021,7, Misgurnus anguillicaudatus,Misgurnus anguillicaudatus,Cobitidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Misgurnus-anguillicaudatus.html,5,25,20,Wide,Not stated,Not stated,Not stated,Exp,25,Within,15,Within,-10,Decrease,10,-10,0,two weeks ; CpG for 24 hours,15,Time sample taken post temp first changed,Molecular,qPCR ,Intestine,Gene,NLRP3,1,Same,FALSE,Chemical,CpG ODN,N,China ,Aquaculture,100,not stated ,209,Chronic,Acute,1,,NLRP3,NLR,PRR,,NLRP3,Unknown,Unknown,NLRP3,NLRP3,scaffold/adaptor protein,0,0,0,1,1,1,0,1,1,0,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,COX2,0.2,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,210,Chronic,Acute,0.38,,COX2,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX2,mt-co2,COX2,COX2,COX2,oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IFN-g,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,211,Chronic,Acute,0.38,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-10,2.5,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,212,Chronic,Acute,0.38,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-1b,5,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,213,Chronic,Acute,0.38,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-21,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,214,Chronic,Acute,0.38,,IL-21,B cell regulator,B cell response,,Unknown,il21,Unknown,il21,IL21,interleukin superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-6,7,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,215,Chronic,Acute,0.38,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-8,3.5,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,216,Chronic,Acute,0.38,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,lysc,2,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,217,Chronic,Acute,0.38,,lysc,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,TLR-1,4,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,218,Chronic,Acute,0.38,,TLR-1,TLR pathway,PRR,,Unknown,tlr1,Unknown,tlr1,TLR1,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, M.J., Jiang, M., Peng, X.X. and Li, H., 2021. Myo-inositol restores tilapia’s ability against infection by aeromonas sobria in higher water temperature. Frontiers in Immunology, p.3654.",2021,8,tilapia,Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile ,Juvenile,Not stated,Exp,18,Within,33,Within,15,Increase,19,0,0,7 days acclimation prior to bacterial challenge. Asessed at 9 hours,7.375,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,TNF-a,0.7,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,30,2,219,Chronic,Acute,0.38,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Islam, M.J., Kunzmann, A., Henjes, J. and Slater, M.J., 2021. Can dietary manipulation mitigate extreme warm stress in fish? The case of European seabass, Dicentrarchus labrax. Aquaculture, 545, p.737153.",2021,9,Seabass (Dicentrarchus labrax),Dicentrarchus labrax,Moronidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Dicentrarchus-labrax.html,8,24,16,Wide,Juvenile ,Juvenile,Not stated,Exp ,22,Within,32,Above,10,Increase,24,8,8,Temperature raised f3.5C over three days and temp stayed at 32C for 18 days,21,Time sample taken post temp first changed,Molecular,qPCR,Dorsal muscle,Gene,HSP70,0.9,Decrease,FALSE,NA,NA,NA,Germany,Aquaculture,3,3,220,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Islam, M.J., Kunzmann, A., Henjes, J. and Slater, M.J., 2021. Can dietary manipulation mitigate extreme warm stress in fish? The case of European seabass, Dicentrarchus labrax. Aquaculture, 545, p.737153.",2021,9,Seabass (Dicentrarchus labrax),Dicentrarchus labrax,Moronidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Dicentrarchus-labrax.html,8,24,16,Wide,Juvenile ,Juvenile,Not stated,Exp ,22,Within,32,Above,10,Increase,24,8,8,Temperature raised f3.5C over three days and temp stayed at 32C for 18 days,21,Time sample taken post temp first changed,Molecular,qPCR,Dorsal muscle,Gene,Igf1,0.5,Decrease,FALSE,NA,NA,NA,Germany,Aquaculture,3,3,221,Chronic,NA,NA,,Igf1,Growth factor,Growth factor,,IGF1,igf1,Unknown,igf1,IGF1,Growth factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Topal, A., Özdemir, S., Arslan, H. and Çomakl?, S., 2021. How does elevated water temperature affect fish brain?(A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes). Fish & Shellfish Immunology, 115, pp.198-204.",2021,10,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,5 months,Not stated,Not stated,Exp,10,Within,25,Above,15,Increase,15,1,1,Temperatures were raised and left for 1 week ,7,Time sample taken post temp first changed,Molecular,qPCR,Brain tissue ,Gene,Catalase,0.25,Decrease,FALSE,NA,NA,NA,Turkey ,Aquaculture,12,3,222,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Topal, A., Özdemir, S., Arslan, H. and Çomakl?, S., 2021. How does elevated water temperature affect fish brain?(A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes). Fish & Shellfish Immunology, 115, pp.198-204.",2021,10,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,5 months,Juvenile,Not stated,Exp,10,Within,25,Above,15,Increase,15,1,1,Temperatures were raised and left for 1 week ,7,Time sample taken post temp first changed,Molecular,qPCR,Brain tissue ,Gene,GPx,0.2,Decrease,FALSE,NA,NA,NA,Turkey ,Aquaculture,12,3,223,Chronic,NA,NA,,GPx,Peroxidase,Degradative enzyme,,Unknown,gpx1a,Unknown,gpx1a,GPX1,peroxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Topal, A., Özdemir, S., Arslan, H. and Çomakl?, S., 2021. How does elevated water temperature affect fish brain?(A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes). Fish & Shellfish Immunology, 115, pp.198-204.",2021,10,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,5 months,Juvenile,Not stated,Exp,10,Within,25,Above,15,Increase,15,1,1,Temperatures were raised and left for 1 week ,7,Time sample taken post temp first changed,Molecular,qPCR,Brain tissue ,Gene,HSP70,2,Increase,FALSE,NA,NA,NA,Turkey ,Aquaculture,12,3,224,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Topal, A., Özdemir, S., Arslan, H. and Çomakl?, S., 2021. How does elevated water temperature affect fish brain?(A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes). Fish & Shellfish Immunology, 115, pp.198-204.",2021,10,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,5 months,Juvenile,Not stated,Exp,10,Within,25,Above,15,Increase,15,1,1,Temperatures were raised and left for 1 week ,7,Time sample taken post temp first changed,Molecular,qPCR,Brain tissue ,Gene,HSP90,2,Increase,FALSE,NA,NA,NA,Turkey ,Aquaculture,12,3,225,Chronic,NA,NA,,HSP90,Heat stress,Heat stress,,Unknown,hsp90ab1,Unknown,hsp90ab1,HSP90AA1,Hsp90 family chaperone,1,1,1,1,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,1,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Topal, A., Özdemir, S., Arslan, H. and Çomakl?, S., 2021. How does elevated water temperature affect fish brain?(A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes). Fish & Shellfish Immunology, 115, pp.198-204.",2021,10,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,5 months,Juvenile,Not stated,Exp,10,Within,25,Above,15,Increase,15,1,1,Temperatures were raised and left for 1 week ,7,Time sample taken post temp first changed,Molecular,qPCR,Brain tissue ,Gene,SOD,0.4,Decrease,FALSE,NA,NA,NA,Turkey ,Aquaculture,12,3,226,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,10,Increase,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,227,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GPx,3,Increase,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,228,Acute,NA,NA,,GPx,Peroxidase,Degradative enzyme,,Unknown,gpx1a,Unknown,gpx1a,GPX1,peroxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-10,1,Same,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,229,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-1b,1.5,Increase,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,230,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,2,Increase,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,231,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yassine, T., Khalafalla, M.M., Mamdouh, M., Elbialy, Z.I., Salah, A.S., Ahmedou, A., Mamoon, A., El-Shehawi, A.M., Van Doan, H. and Dawood, M.A., 2021. The enhancement of the growth rate, intestinal health, expression of immune-related genes, and resistance against suboptimal water temperature in common carp (Cyprinus carpio) by dietary paraprobiotics. Aquaculture Reports, 20, p.100729.",2021,11,common carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,24,Within,14,Within,-10,Decrease,11,-21,0,48 hours,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TNF-a,1,Same,FALSE,Other,Lactobacillus supplemented diet,N,Egypt,Aquaculture,3,,232,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Cheng, Y., Li, X., Wang, L., Lu, K., Song, K., Ai, Q., Mai, K. and Zhang, C., 2021. Effects of dietary arginine levels on growth, immune function of physical barriers and serum parameters of spotted seabass (Lateolabrax maculatus) reared at different water temperatures. Aquaculture, 541, p.736812.",2021,12,Spotted seabass(Lateolabrax maculatus),Lateolabrax maculatus,Lateolabracidae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Lateolabrax-japonicus.html,12.7,26.3,13.6,Wide,Juvenile ,Juvenile,Not stated,Exp,27,Above,33,Above,6,Increase,20.3,6.7,6.7,14 days ,14,Time sample taken post temp first changed,Molecular,qPCR,Intestine,Gene,MAPK p38,4,Increase,FALSE,Other,dietary arginine but comparing groups where these levels are the same; mid value so 2.44 % arginine,N,China,Aquaculture,9,4,233,Chronic,NA,NA,,MAPK p38,Intracellular signalling,Intracellular signalling,,Unknown,mapk1,Unknown,mapk1,MAPK1,non-receptor serine/threonine protein kinase,1,1,0,1,1,0,0,1,0,1,0,0,0,0,0,0,0,1,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,1,1,1,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,1,0,0,0,0,1,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Cheng, Y., Li, X., Wang, L., Lu, K., Song, K., Ai, Q., Mai, K. and Zhang, C., 2021. Effects of dietary arginine levels on growth, immune function of physical barriers and serum parameters of spotted seabass (Lateolabrax maculatus) reared at different water temperatures. Aquaculture, 541, p.736812.",2021,12,Spotted seabass(Lateolabrax maculatus),Lateolabrax maculatus,Lateolabracidae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Lateolabrax-japonicus.html,12.7,26.3,13.6,Wide,Juvenile ,Juvenile,Not stated,Exp,27,Above,33,Above,6,Increase,20.3,6.7,6.7,14 days ,14,Time sample taken post temp first changed,Molecular,qPCR,Intestine,Gene,MyD88,1,Same,FALSE,Other,dietary arginine but comparing groups where these levels are the same; mid value so 2.44 % arginine,N,China,Aquaculture,9,4,234,Chronic,NA,NA,,MyD88,TLR pathway,PRR,,MYD88,myd88,Unknown,myd88,MYD88,scaffold/adaptor protein,1,1,0,1,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Cheng, Y., Li, X., Wang, L., Lu, K., Song, K., Ai, Q., Mai, K. and Zhang, C., 2021. Effects of dietary arginine levels on growth, immune function of physical barriers and serum parameters of spotted seabass (Lateolabrax maculatus) reared at different water temperatures. Aquaculture, 541, p.736812.",2021,12,Spotted seabass(Lateolabrax maculatus),Lateolabrax maculatus,Lateolabracidae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Lateolabrax-japonicus.html,12.7,26.3,13.6,Wide,Juvenile ,Juvenile,Not stated,Exp,27,Above,33,Above,6,Increase,20.3,6.7,6.7,14 days ,14,Time sample taken post temp first changed,Molecular,qPCR,Intestine,Gene,TLR-4,40,Increase,FALSE,Other,dietary arginine but comparing groups where these levels are the same; mid value so 2.44 % arginine,N,China,Aquaculture,9,4,235,Chronic,NA,NA,,TLR-4,TLR pathway,PRR,,Unknown,Unknown,Unknown,TLR-4,TLR4,Unknown,0,0,0,1,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,HSP70,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,236,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,HSP70,6,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,237,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,HSP70,1.3,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,238,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,HSP70,3.5,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,239,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,HSP70,6,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,240,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,HSP70,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,241,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,IL-1b,30,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,242,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,IL-1b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,50,3,243,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-1b,1.25,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,244,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,IL-1b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,50,3,245,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,IL-1b,5,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,246,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IL-1b,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,247,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,TGF-b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,50,3,248,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,TGF-b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,50,3,249,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,25,Above,10,Increase,24,6,6,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,TGF-b,0.8,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,50,3,250,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,TGF-b,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,251,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post temp first changed,Molecular,qPCR,Liver  ,Gene,TGF-b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,50,3,252,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Yang, S., Yang, X., Li, Y., Li, D., Gong, Q., Huang, X., Wu, J., Huang, A., Kong, F., Han, X. and Zeng, X., 2021. The multilevel responses of Acipenser baerii and its hybrids (A. baerii?× A. schrenckii?) to chronic heat stress. Aquaculture, 541, p.736773.",2021,13,Acipenser baerii,Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,Not stated,Not stated,Not stated,Exp,15,Within,28,Above,13,Increase,27,9,9,7-12 days (7 days to reach final temperature),12,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,TGF-b,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,50,3,253,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge up to 72 hours (temp change begun at 60 hours); measured responses daily afterwards). 72 hrs post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,CD8a,2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,254,Chronic,Chronic,3,,CD8,T cell,T cell response,,CD8A,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge; measured responses daily afterwards). 72 hours post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,IFNI,2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,255,Chronic,Chronic,3,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge; measured responses daily afterwards). 24 hours post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,IL-1b,2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,256,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge; measured responses daily afterwards). 48 hours post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,MHC I,2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,257,Chronic,Acute,2,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge; measured responses daily afterwards). 12 hours post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,Mx,3,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,258,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Xing, J., Sheng, X., Chi, H. and Zhan, W., 2021. Effect of raising water temperature on proliferation of hirame novirhabdovirus (HIRRV) and antiviral response of olive flounder (Paralichthys olivaceus). Aquaculture, 540, p.736751.",2021,14,olive flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,Not stated,Not stated,Not stated,Exp,10,Within,20,Within,10,Increase,11.4,-5,0,15 days (though different groups raised Temp at different times after challenge; measured responses daily afterwards). 24 hours post infection,15,Time sample taken post infection - v close to temp change point,Molecular,qPCR,Spleen,Gene,TNF-a,2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,90,2,259,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL like a,1.5,Increase,FALSE,NA,NA,NA,China ,Wild,4,3,260,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL like a,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL like a,0.5,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,261,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL like a,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL like b,2,Increase,FALSE,NA,NA,NA,China ,Wild,4,3,262,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL like b,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL like b,0.5,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,263,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL like b,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL1 ,1.2,Increase,FALSE,NA,NA,NA,China ,Wild,4,3,264,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL1 ,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL1 ,0.1,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,265,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL1 ,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL2,1,Same,FALSE,NA,NA,NA,China ,Wild,4,3,266,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL2,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL2,0.2,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,267,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL2,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL3,1.5,Increase,FALSE,NA,NA,NA,China ,Wild,4,3,268,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL3,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL3,0.4,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,269,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL3,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,2,Below,-10,Decrease,-8,-22,-8,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL4,1,Same,FALSE,NA,NA,NA,China ,Wild,4,3,270,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL4,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Ma, H., Han, Y.C., Palti, Y., Gao, G., Liu, S., Palmquist, D.E., Wiens, G.D. and Shepherd, B.S., 2021. Structure and regulation of the NK-lysin (1–4) and NK-lysin like (a and b) antimicrobial genes in rainbow trout (Oncorhynchus mykiss). Developmental & Comparative Immunology, 116, p.103961.",2021,15,Rainbow trout ,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,12,Within,25,Above,13,Increase,15,1,1,6 hours (from Sanchez et al referred to in paper),0.25,Time sample taken post temp first changed,Molecular,qPCR,Gill,Gene,NKL4,0.25,Decrease,FALSE,NA,NA,NA,China ,Wild,4,3,271,Acute,NA,NA,,NKL,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,NKL4,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,13,Below,-12,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFN,0.1,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,272,Chronic,NA,NA,,IFN,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,17,Below,-8,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFN,0.1,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,273,Chronic,NA,NA,,IFN,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,21,Below,-4,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFN,0.3,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,274,Chronic,NA,NA,,IFN,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,13,Below,-12,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFNR,0.3,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,275,Chronic,NA,NA,,IFNR,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IFNR ,IFNAR1,Unknown,1,0,0,1,0,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,21,Below,-4,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFNR,0.5,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,276,Chronic,NA,NA,,IFNR,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IFNR ,IFNAR1,Unknown,1,0,0,1,0,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,17,Below,-8,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IFNR,0.25,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,277,Chronic,NA,NA,,IFNR,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IFNR ,IFNAR1,Unknown,1,0,0,1,0,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,13,Below,-12,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4,0.25,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,278,Chronic,NA,NA,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,17,Below,-8,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4,0.5,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,279,Chronic,NA,NA,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,21,Below,-4,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4,0.6,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,280,Chronic,NA,NA,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,13,Below,-12,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4R,0.6,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,281,Chronic,NA,NA,,IL-4R,Th2/17 pathway,Th2/17 pathway,,Unknown,il4r.1,Unknown,il4r.1,IL4R,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,17,Below,-8,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4R,0.6,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,282,Chronic,NA,NA,,IL-4R,Th2/17 pathway,Th2/17 pathway,,Unknown,il4r.1,Unknown,il4r.1,IL4R,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wen, X., Chu, P., Xu, J., Wei, X., Fu, D., Wang, T. and Yin, S., 2021. Combined effects of low temperature and salinity on the immune response, antioxidant capacity and lipid metabolism in the pufferfish (Takifugu fasciatus). Aquaculture, 531, p.735866.",2021,16,pufferfish (Takifugu fascitus),Takifugu fasciatus,Tetraodontidae,NS,NS,NS,NA,NS,NS,NA,NA,Not stated ,Not stated,Not stated,Exp,25,Below,21,Below,-4,Decrease,NA,NA,NA,96 hours ,4,Time sample taken post temp first changed,Molecular,qPCR,Liver ,Gene,IL-4R,0.6,Decrease,FALSE,NA,NA,NA,China ,Aquaculture,9,3,283,Chronic,NA,NA,,IL-4R,Th2/17 pathway,Th2/17 pathway,,Unknown,il4r.1,Unknown,il4r.1,IL4R,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IgM-antigen specific,0.3,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,284,Chronic,Chronic,7,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IgM-antigen specific,0.6,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,285,Chronic,Acute,1,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IgT,0.05,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,286,Chronic,Chronic,7,,IgT,Antibody,B cell response,,Unknown,Unknown,Unknown,IgT,IGH,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IgT,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,287,Chronic,Acute,1,,IgT,Antibody,B cell response,,Unknown,Unknown,Unknown,IgT,IGH,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,288,Chronic,Chronic,7,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-10,2,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,289,Chronic,Acute,1,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,6,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,290,Chronic,Chronic,7,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,IL-1b,1.8,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,291,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,NOD1,0.8,Decrease,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,292,Chronic,Chronic,7,,NOD,NLR,PRR,,NOD1,nod1,Unknown,nod1,NOD1,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,NOD1,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,293,Chronic,Acute,1,,NOD,NLR,PRR,,NOD1,nod1,Unknown,nod1,NOD1,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,NOD2,2,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,294,Chronic,Chronic,7,,NOD,NLR,PRR,,NOD2,nod2,Unknown,nod2,NOD2,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,NOD2,1,Same,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,295,Chronic,Acute,1,,NOD,NLR,PRR,,NOD2,nod2,Unknown,nod2,NOD2,scaffold/adaptor protein,1,1,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 7 post infection,21,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,6,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,296,Chronic,Chronic,7,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"He, R.Z., Li, Z.C., Li, S.Y. and Li, A.X., 2021. Development of an immersion challenge model for Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 531, p.735877.",2021,17,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,29,Within,33,Within,4,Increase,19,0,0,14 days; measured at day 1 post infection,15,Time sample taken post temp first changed,Molecular,qPCR,Head kidney,Gene,TNF-a,4,Increase,FALSE,Bacterial,Bacterial,Y,China ,Aquaculture,35,3,297,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,IL-1b,0.7,Decrease,FALSE,Chemical,Y - LTA,N,China ,Aquaculture,,,298,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,IL-8,0.8,Decrease,FALSE,Chemical,Y - LPS/LTA/PolyI:C,N,China ,Aquaculture,,,299,Chronic,Acute,1,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR20a,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,300,Chronic,NA,NA,,TLR20a,TLR pathway,PRR,,Unknown,tlr20.1,Unknown,tlr20.1,TLR1,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR20f,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,301,Chronic,NA,NA,,TLR20f,TLR pathway,PRR,,TLR20F,tlr20.1,Unknown,tlr20.1,TLR1,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR-21,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,302,Chronic,NA,NA,,TLR-21,TLR pathway,PRR,no human homolog but most similar in ligand binding (and phylogenetics) to TLR3,unknown,tlr21,tlr21,tlr21,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR-21,0.7,Decrease,FALSE,Chemical,Y - polyI:C,N,China ,Aquaculture,,,303,Chronic,Acute,1,,TLR-21,TLR pathway,PRR,no human homolog but most similar in ligand binding (and phylogenetics) to TLR3,unknown,tlr21,tlr21,tlr21,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR-3,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,304,Chronic,NA,NA,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR-3,0.6,Decrease,FALSE,Chemical,Y - LPS,N,China ,Aquaculture,,,305,Chronic,Acute,1,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR-3,0.5,Decrease,FALSE,Chemical,Y-polyI:C,N,China ,Aquaculture,,,306,Chronic,Acute,1,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR4a,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,307,Chronic,NA,NA,,TLR-4,TLR pathway,PRR,,Unknown,tlr4ba,Unknown,tlr4ba,TLR4,transmembrane signal receptor,0,0,0,1,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR4b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,308,Chronic,NA,NA,,TLR-4,TLR pathway,PRR,,Unknown,tlr4ba,Unknown,tlr4ba,TLR4,transmembrane signal receptor,0,0,0,1,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR5a,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,309,Chronic,NA,NA,,TLR-5,TLR pathway,PRR,,TLR5A,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR5a,0.5,Decrease,FALSE,Chemical,Y- LPS,N,China ,Aquaculture,,,310,Chronic,Acute,1,,TLR-5,TLR pathway,PRR,,TLR5A,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR5b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,,,311,Chronic,NA,NA,,TLR-5,TLR pathway,PRR,,TLR5B,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TLR5b,0.4,Decrease,FALSE,Chemical,Y - LPS,N,China ,Aquaculture,,,312,Chronic,Acute,1,,TLR-5,TLR pathway,PRR,,TLR5B,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Chen, H., Liang, Y., Han, Y., Liu, T. and Chen, S., 2021. Genome?wide analysis of Toll?like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection. Journal of Fish Diseases, 44(3), pp.337-349.",2021,18,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,adult ,Adult,Equal ratio,Exp ,28,Above,18,Within,-10,Decrease,0,-6,0,5 days for temperature and then within 24 hours post stimulant,6,Time sample taken post temp first changed,Molecular,qPCR,Visceral mass,Gene,TNF-a,0.6,Decrease,FALSE,Chemical,Y - LPS or polyI:C,N,China ,Aquaculture,,,313,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,IL-10,0.5,Decrease,FALSE,Chemical,organic acids monoterpenes and aldehydes,N,Italy,Aquaculture,5,not stated,314,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,IL-1b,1.2,Increase,FALSE,Chemical,organic acids monoterpenes and aldehydes but compared groups on same diet so this not a compounding factor,N,Italy,Aquaculture,5,not stated,315,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,IL-6,1,Same,FALSE,Chemical,organic acids monoterpenes and aldehydes,N,Italy,Aquaculture,5,not stated,316,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,IL-8,2,Increase,FALSE,Chemical,organic acids monoterpenes and aldehydes,N,Italy,Aquaculture,5,not stated,317,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,TGF-b,1,Same,FALSE,Chemical,organic acids monoterpenes and aldehydes,N,Italy,Aquaculture,5,not stated,318,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Pelusio, N.F., Rossi, B., Parma, L., Volpe, E., Ciulli, S., Piva, A., D'Amico, F., Scicchitano, D., Candela, M., Gatta, P.P. and Bonaldo, A., 2020. Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature. Fish & Shellfish Immunology, 107, pp.324-335.",2020,19,Rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Juvenile ,Juvenile,Not stated,Exp ,15,Within,23,Within,8,Increase,13,-1,0,1 week,7,Time sample taken post temp first changed,Molecular,qPCR,intestinal mucosa ,Gene,TNF-a,2,Increase,FALSE,Chemical,organic acids monoterpenes and aldehydes,N,Italy,Aquaculture,5,not stated,319,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,Ifn I-3,800,Increase,TRUE,Viral,Viral,Y,China ,Aquaculture,30,not stated,320,Chronic,Chronic,3,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,Ifn I-3,700,Increase,TRUE,Viral,Viral,Y,China ,Aquaculture,33,not stated,321,Chronic,Chronic,3,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IFN-g,10,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,322,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,IFN-g,5,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,34,not stated,323,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,irf3,20,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,324,Chronic,Chronic,3,,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,irf3,15,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,31,not stated,325,Chronic,Chronic,3,,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,irf7,9,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,326,Chronic,Chronic,3,,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,irf7,5,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,32,not stated,327,Chronic,Chronic,3,,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,lgp2,80,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,328,Chronic,Chronic,3,,lgp2,RLR pathway,PRR,,Unknown,dhx58,Unknown,dhx58,DHX58,Unknown,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,lgp2,40,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,329,Chronic,Chronic,3,,lgp2,RLR pathway,PRR,,Unknown,dhx58,Unknown,dhx58,DHX58,Unknown,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,mavs,8,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,330,Chronic,Chronic,3,,mavs,RLR pathway,PRR,,MAVS,mavs,Unknown,mavs,MAVS,Unknown,0,0,0,1,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,mavs,6,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,331,Chronic,Chronic,3,,mavs,RLR pathway,PRR,,MAVS,mavs,Unknown,mavs,MAVS,Unknown,0,0,0,1,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,MDA5,6,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,332,Chronic,Chronic,3,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,MDA5,3,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,333,Chronic,Chronic,3,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,10,Within,-6,Decrease,1.4,-15,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,mita,30,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,334,Chronic,Chronic,3,,mita,Anti-viral,PRR,,Unknown,sting1,Unknown,sting1,STING1,Unknown,0,0,0,1,1,1,0,1,1,0,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Wang, H., Tang, X., Sheng, X., Xing, J., Chi, H. and Zhan, W., 2020. Transcriptome analysis reveals temperature-dependent early immune response in flounder (Paralichthys olivaceus) after Hirame novirhabdovirus (HIRRV) infection. Fish & Shellfish Immunology, 107, pp.367-378.",2020,20,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,16,Within,20,Within,4,Increase,11.4,-5,0,2 weeks ; measurements 72 hours post infection (though time course in paper). Fold increase over no infection (time zero),17,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,mita,15,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,30,not stated,335,Chronic,Chronic,3,,mita,Anti-viral,PRR,,Unknown,sting1,Unknown,sting1,STING1,Unknown,0,0,0,1,1,1,0,1,1,0,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,camp-b,1,Same,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,336,Chronic,Acute,1,,Camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,camp-b,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,COX4,0.3,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,337,Chronic,Acute,1,,COX4,Eicosanoid sythesis,Eicosanoid synthesis,,Unknown,Unknown,cox4i2,cox4i2,COX4I1,oxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,hamp-a,0.2,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,338,Chronic,Acute,1,,hamp-a,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IFN-g,0.5,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,339,Chronic,Acute,1,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IL-8,0.8,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,340,Chronic,Acute,1,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IL-1b,0.2,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,341,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,irf7-b,1.3,Increase,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,342,Chronic,Acute,1,,irf7,Anti-viral signalling,PRR,,Unknown,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,isg15a,0.5,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,343,Chronic,Acute,1,,isg15,RLR pathway,PRR,,Unknown,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,Mx-b,0.5,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,344,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxb,Unknown,mxb,MX2,membrane traffice protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,Stat1b,0.5,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,345,Chronic,Acute,1,,STAT,Cytokine signalling,Cytokine signalling,,STAT1B,stat1b,Unknown,stat1b,STAT1,DNA-binding transcription factor,1,1,1,0,0,1,1,1,1,0,1,0,1,1,0,1,1,0,0,0,0,1,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,stlr5-a,0.2,Decrease,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,346,Chronic,Acute,1,,stlr5-a,TLR pathway,PRR,,Unknown,tlr5a,Unknown,tlr5a,TLR5,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 10/11/22,"Zanuzzo, F.S., Beemelmanns, A., Hall, J.R., Rise, M.L. and Gamperl, A.K., 2020. The innate immune response of Atlantic salmon (Salmo salar) is not negatively affected by high temperature and moderate hypoxia. Frontiers in immunology, 11, p.1009.",2020,21,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated ,Not stated,Not stated,Exp,12,Above,20,Above,8,Increase,18,11,11,four weeks and 24 hours post vaccine,29,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,viperin-b,1,Same,FALSE,Other,Vaccine,N,Canada ,Aquaculture,6,not stated,347,Chronic,Acute,1,,viperin-b,RLR pathway,PRR,,Unknown,rsad2,Unknown,rsad2,RSAD2,Unknown,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IFN-g,0.1,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,348,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IFN-g,1.5,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,349,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IFN-g,0.1,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,350,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g,0.1,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,351,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g,3,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,352,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g,0.3,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,353,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IgM-antigen specific,0.3,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,354,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IgM-antigen specific,10,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,355,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IgM-antigen specific,1,Same,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,356,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IgM-antigen specific,0.15,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,357,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IgM-antigen specific,1.5,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,358,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IgM-antigen specific,0.3,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,359,Chronic,Chronic,3,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IL-1b,0.1,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,360,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IL-1b,4,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,361,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IL-1b,0.5,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,362,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,0.4,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,363,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,2,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,364,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,0.5,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,365,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,TNF-a,0.25,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,366,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,TNF-a,1.5,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,367,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,TNF-a,0.6,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,368,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,21,Within,-4,Decrease,7,-12,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,0.2,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,369,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,29,Within,4,Increase,15,-4,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1.2,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,370,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wang, J., Lu, D.Q., Jiang, B., Mo, X.B., Du, J.J. and Li, A.X., 2020. Influence of temperature on the vaccine efficacy against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 521, p.734943.",2020,22,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp,25,Within,33,Within,8,Increase,19,0,0,>3 days. Temperature attained by vaccine point. Measured day 3 post vaccine,6,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,0.5,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,20,not stated ,371,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,Catalase,2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,372,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,1.2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,373,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,GSH-Px,1.2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,374,Acute,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GSH-Px,0.9,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,375,Acute,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,Hepcidin-1,0.5,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,376,Acute,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Hepcidin-1,0.01,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,377,Acute,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,Hepcidin-2,0.1,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,378,Acute,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Hepcidin-2,0.01,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,379,Acute,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,IL-10,0.5,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,380,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-10,0.1,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,381,Acute,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,IL-15,0.5,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,382,Acute,NA,NA,,IL-15,T cell supporting cytokine,T cell response,,Unknown,il15,Unknown,il15,IL15,interleukin superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-15,0.6,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,383,Acute,NA,NA,,IL-15,T cell supporting cytokine,T cell response,,Unknown,il15,Unknown,il15,IL15,interleukin superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,IL-1b,0.1,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,384,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-1b,0.01,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,385,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,IL-8,0.6,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,386,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-8,0.15,Decrease,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,387,Acute,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,SOD1,1.2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,388,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD1,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD1,3,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,389,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD1,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,SOD2,1.5,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,390,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD2,1.1,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,391,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,SOD3a,3,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,392,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD3A,sod3a,Unknown,sod3a,SOD3,Oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD3a,2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,393,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD3A,sod3a,Unknown,sod3a,SOD3,Oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,SOD3b,4,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,394,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD3B,sod3b,Unknown,sod3b,SOD3,Oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD3b,1.7,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,395,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD3B,sod3b,Unknown,sod3b,SOD3,Oxidoreductase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,TGF-b1,1.5,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,396,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TGF-b1,1,Same,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,397,Acute,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Gill  ,Gene,TNF-a,2,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,398,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Sun, J.L., Zhao, L.L., Liao, L., Tang, X.H., Cui, C., Liu, Q., He, K., Ma, J.D., Jin, L., Yan, T. and Zhou, J., 2020. Interactive effect of thermal and hypoxia on largemouth bass (Micropterus salmoides) gill and liver: Aggravation of oxidative stress, inhibition of immunity and promotion of cell apoptosis. Fish & shellfish immunology, 98, pp.923-936.",2020,23,Large mouth bass (Micropterus salomoides),Micropterus salomoides,Centrarchidae,Freshwater,Subtropical,N,https://www.fishbase.se/summary/Micropterus-salmoides.html,10,32,22,Wide,Not stated,Not stated,Not stated,Exp,20,Within,26,Within,6,Increase,16,-6,0,12 hours,0.5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TNF-a,1.5,Increase,FALSE,Other,Hypoxia,N,China ,Aquaculture,180,6,399,Acute,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Aidos, L., Cafiso, A., Bertotto, D., Bazzocchi, C., Radaelli, G. and Di Giancamillo, A., 2020. How different rearing temperatures affect growth and stress status of Siberian sturgeon Acipenser baerii larvae. Journal of Fish Biology, 96(4), pp.913-924.",2020,24,Siberian sturgeon (Acipenser baerii),Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,hatched larvae ,Larval,Not stated,Exp,16,Within,19,Within,3,Increase,18,0,0,Until schooling phase (approx days 3-5),5,Time sample taken post temp first changed,Molecular ,qPCR,hatched larvae,Gene,HSP70,0.5,Decrease,FALSE,NA,NA,N,Italy ,Aquaculture,not stated ,3,400,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Aidos, L., Cafiso, A., Bertotto, D., Bazzocchi, C., Radaelli, G. and Di Giancamillo, A., 2020. How different rearing temperatures affect growth and stress status of Siberian sturgeon Acipenser baerii larvae. Journal of Fish Biology, 96(4), pp.913-924.",2020,24,Siberian sturgeon (Acipenser baerii),Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,hatched larvae ,Larval,Not stated,Exp,16,Within,22,Above,6,Increase,21,3,3,Until schooling phase (approx days 3-5),5,Time sample taken post temp first changed,Molecular ,qPCR,hatched larvae,Gene,HSP70,0.5,Decrease,FALSE,NA,NA,N,Italy ,Aquaculture,not stated ,4,401,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Aidos, L., Cafiso, A., Bertotto, D., Bazzocchi, C., Radaelli, G. and Di Giancamillo, A., 2020. How different rearing temperatures affect growth and stress status of Siberian sturgeon Acipenser baerii larvae. Journal of Fish Biology, 96(4), pp.913-924.",2020,24,Siberian sturgeon (Acipenser baerii),Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,hatched larvae ,Larval,Not stated,Exp,16,Within,19,Within,3,Increase,18,0,0,Until schooling phase (approx days 3-5),5,Time sample taken post temp first changed,Molecular ,qPCR,hatched larvae,Gene,Igf1,0.5,Decrease,FALSE,NA,NA,N,Italy ,Aquaculture,not stated ,5,402,Chronic,NA,NA,,Igf1,Growth factor,Growth factor,,IGF1,igf1,Unknown,igf1,IGF1,Growth factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Aidos, L., Cafiso, A., Bertotto, D., Bazzocchi, C., Radaelli, G. and Di Giancamillo, A., 2020. How different rearing temperatures affect growth and stress status of Siberian sturgeon Acipenser baerii larvae. Journal of Fish Biology, 96(4), pp.913-924.",2020,24,Siberian sturgeon (Acipenser baerii),Acipenser baerii,Acipenseridae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Acipenser-baerii.html,1,19,18,Wide,hatched larvae ,Larval,Not stated,Exp,16,Within,22,Above,6,Increase,21,3,3,Until schooling phase (approx days 3-5),5,Time sample taken post temp first changed,Molecular ,qPCR,hatched larvae,Gene,Igf1,0.3,Decrease,FALSE,NA,NA,N,Italy ,Aquaculture,not stated ,6,403,Chronic,NA,NA,,Igf1,Growth factor,Growth factor,,IGF1,igf1,Unknown,igf1,IGF1,Growth factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Ignatz, E.H., Braden, L.M., Benfey, T.J., Caballero-Solares, A., Hori, T.S., Runighan, C.D., Fast, M.D., Westcott, J.D. and Rise, M.L., 2020. Impact of rearing temperature on the innate antiviral immune response of growth hormone transgenic female triploid Atlantic salmon (Salmo salar). Fish & shellfish immunology, 97, pp.656-668.",2020,25,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,hatchlings ,Larval,F,Exp ,13,Above,10,Above,-3,Decrease,8,1,1,From feeding fry to 800g weight. Sample taken 24 hours post injection (time course but taking this as peak),500,"Having to estimate growth rate of fish. From https://www.researchgate.net/figure/Growth-performance-average-salmon-weight-from-fry-stage-to-market-size-for-the-three_fig4_303095240, using St Johns data to match paper, indicates 500 days",Molecular ,qPCR,Head kidney,Gene,Mx-b,1,Same,FALSE,Chemical,pI:C,N,Canada ,Aquaculture,12,3,404,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxb,Unknown,mxb,MX2,membrane traffice protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Ignatz, E.H., Braden, L.M., Benfey, T.J., Caballero-Solares, A., Hori, T.S., Runighan, C.D., Fast, M.D., Westcott, J.D. and Rise, M.L., 2020. Impact of rearing temperature on the innate antiviral immune response of growth hormone transgenic female triploid Atlantic salmon (Salmo salar). Fish & shellfish immunology, 97, pp.656-668.",2020,25,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,hatchlings ,Larval,F,Exp ,13,Above,16,Above,3,Increase,14,7,7,From feeding fry to 800g weight. Sample taken 24 hours post injection (time course but taking this as peak),500,"Having to estimate growth rate of fish. From https://www.researchgate.net/figure/Growth-performance-average-salmon-weight-from-fry-stage-to-market-size-for-the-three_fig4_303095240, using St Johns data to match paper, indicates 500 days",Molecular ,qPCR,Head kidney,Gene,Mx-b,1,Same,FALSE,Chemical,pI:C,N,Canada ,Aquaculture,12,3,405,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxb,Unknown,mxb,MX2,membrane traffice protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Ignatz, E.H., Braden, L.M., Benfey, T.J., Caballero-Solares, A., Hori, T.S., Runighan, C.D., Fast, M.D., Westcott, J.D. and Rise, M.L., 2020. Impact of rearing temperature on the innate antiviral immune response of growth hormone transgenic female triploid Atlantic salmon (Salmo salar). Fish & shellfish immunology, 97, pp.656-668.",2020,25,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,hatchlings ,Larval,F,Exp ,13,Above,16,Above,3,Increase,14,7,7,From feeding fry to 800g weight. Sample taken 24 hours post injection (time course but taking this as peak),500,"Having to estimate growth rate of fish. From https://www.researchgate.net/figure/Growth-performance-average-salmon-weight-from-fry-stage-to-market-size-for-the-three_fig4_303095240, using St Johns data to match paper, indicates 500 days",Molecular ,qPCR,Head kidney,Gene,rsad-2,1,Same,FALSE,Chemical,pI:C,N,Canada ,Aquaculture,12,3,406,Chronic,Acute,1,,rsad,RLR pathway,PRR,,Unknown,rsad2,Unknown,rsad2,RSAD2,Unknown,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,C3,0.2,Decrease,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,407,Chronic,Chronic,3,,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g1-1,1,Same,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,408,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g1-2,1,Same,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,409,Chronic,Chronic,3,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-11,3,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,410,Chronic,Chronic,3,,IL-11,IL-11,IL-12,,Unknown,il11a,Unknown,il11a,IL11,interleukin superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b1,10,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,411,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b2,6,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,412,Chronic,Chronic,3,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Lysozyme,0.2,Decrease,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,413,Chronic,Chronic,3,,Lysozyme,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Nfkbiab,1,Same,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,414,Chronic,Chronic,3,,NFkB,Intracellular signalling,Intracellular signalling,,unknown,nfkbiab,nfkbiab,nfkbiab,NFKB1,unknown,1,1,0,1,1,0,0,1,1,1,0,0,0,0,1,0,0,1,1,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,1,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,1,1,1,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-2,7,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,415,Chronic,Chronic,3,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-3,1,Same,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,416,Chronic,Chronic,3,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-9,2,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,417,Chronic,Chronic,3,,TLR-9,TLR pathway,PRR,,Unknown,tlr9,Unknown,tlr9,TLR9,transmembrane signal receptor,0,0,0,1,1,0,0,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a1,2,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,418,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,Unknown,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Yang, L.F., Zheng, J., Chen, Z.G. and Peng, B., 2020. Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature. Virulence, 11(1), pp.877-888.",2020,26,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp,18,Within,33,Above,15,Increase,31,11,11,3 weeks and measured 3 days post bacterial challenge,24,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a2,2,Increase,FALSE,Bacterial x Chemical,Bacterial x Maltose but comparing control groups without maltose,Y,China ,Aquaculture,3,not stated ,419,Chronic,Chronic,3,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,Unknown,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Elkatatny, N.M., El Nahas, A.F., Helal, M.A., Fahmy, H.A. and Tanekhy, M., 2020. The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives. Fish & shellfish immunology, 96, pp.270-278.",2020,27,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,one day old larvae ,Larval,Not stated,Exp ,23,Within,30,Within,7,Increase,16,-3,0,"5 days to acclimitise, 21 days diet",26,Time sample taken post temp first changed,Molecular ,qPCR,Larvae,Gene,HSP70,0.01,Decrease,FALSE,Other,Diet but all data from same diet (amino acid) so not a counfounding factor,N,Egypt ,Aquaculture,3,2,420,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Elkatatny, N.M., El Nahas, A.F., Helal, M.A., Fahmy, H.A. and Tanekhy, M., 2020. The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives. Fish & shellfish immunology, 96, pp.270-278.",2020,27,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,one day old larvae ,Larval,Not stated,Exp ,23,Within,30,Within,7,Increase,16,-3,0,"5 days to acclimitise, 21 days diet",26,Time sample taken post temp first changed,Molecular ,qPCR,Larvae,Gene,IL-1b,0.01,Decrease,FALSE,Other,Diet but all data from same diet (amino acid) so not a counfounding factor,N,Egypt ,Aquaculture,3,2,421,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Elkatatny, N.M., El Nahas, A.F., Helal, M.A., Fahmy, H.A. and Tanekhy, M., 2020. The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives. Fish & shellfish immunology, 96, pp.270-278.",2020,27,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,one day old larvae ,Larval,Not stated,Exp ,23,Within,30,Within,7,Increase,16,-3,0,"5 days to acclimitise, 21 days diet",26,Time sample taken post temp first changed,Molecular ,qPCR,Larvae,Gene,IL-8,0.01,Decrease,FALSE,Other,Diet but all data from same diet (amino acid) so not a counfounding factor,N,Egypt ,Aquaculture,3,2,422,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Elkatatny, N.M., El Nahas, A.F., Helal, M.A., Fahmy, H.A. and Tanekhy, M., 2020. The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives. Fish & shellfish immunology, 96, pp.270-278.",2020,27,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,one day old larvae ,Larval,Not stated,Exp ,23,Within,30,Within,7,Increase,16,-3,0,"5 days to acclimitise, 21 days diet",26,Time sample taken post temp first changed,Molecular ,qPCR,Larvae,Gene,rag,2.2,Increase,FALSE,Other,Diet but all data from same diet (amino acid) so not a counfounding factor,N,Egypt ,Aquaculture,3,2,423,Chronic,NA,NA,,rag,B cell regulator,B cell response,,Unknown,rag1,Unknown,rag1,RAG1,endodeoxyribonuclease,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Elkatatny, N.M., El Nahas, A.F., Helal, M.A., Fahmy, H.A. and Tanekhy, M., 2020. The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives. Fish & shellfish immunology, 96, pp.270-278.",2020,27,Nile tilapia (Oreochromis nioticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,one day old larvae ,Larval,Not stated,Exp ,23,Within,30,Within,7,Increase,16,-3,0,"5 days to acclimitise, 21 days diet",26,Time sample taken post temp first changed,Molecular ,qPCR,Larvae,Gene,TLR-7,0.2,Decrease,FALSE,Other,Diet but all data from same diet (amino acid) so not a counfounding factor,N,Egypt ,Aquaculture,3,2,424,Chronic,NA,NA,,TLR-7,TLR pathway,PRR,,Unknown,tlr7,Unknown,tlr7,TLR7,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Song, H., Xu, D., Tian, L., Chen, R., Wang, L., Tan, P. and You, Q., 2019. Overwinter mortality in yellow drum (Nibea albiflora): insights from growth and immune responses to cold and starvation stress. Fish & Shellfish Immunology, 92, pp.341-347.",2019,28,Yellow drum (Nibea albiflora),Nibea albiflora,Sciaenidae,Marine,Temperate,Y,https://www.fishbase.se/summary/Nibea-albiflora.html,16.8,24.7,7.9,Narrow,6 months ,Not stated,Not stated,Exp ,16,Below,8,Below,-8,Decrease,-8.8,-16.7,-8.8,"14 days, time course of response; taken day 14 as a snapshot",14,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,0.9,Decrease,FALSE,Other,Starvation but data from fed control fish in all cases so diet not a counfounding factor,N,China,Aquaculture,4,2,425,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Song, H., Xu, D., Tian, L., Chen, R., Wang, L., Tan, P. and You, Q., 2019. Overwinter mortality in yellow drum (Nibea albiflora): insights from growth and immune responses to cold and starvation stress. Fish & Shellfish Immunology, 92, pp.341-347.",2019,28,Yellow drum (Nibea albiflora),Nibea albiflora,Sciaenidae,Marine,Temperate,Y,https://www.fishbase.se/summary/Nibea-albiflora.html,16.8,24.7,7.9,Narrow,6 months ,Not stated,Not stated,Exp ,16,Below,8,Below,-8,Decrease,-8.8,-16.7,-8.8,"14 days, time course of response; taken day 14 as a snapshot",14,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Cu/Zn-SOD,0.6,Decrease,FALSE,Other,Starvation but data from fed control fish in all cases so diet not a counfounding factor,N,China,Aquaculture,4,2,426,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Song, H., Xu, D., Tian, L., Chen, R., Wang, L., Tan, P. and You, Q., 2019. Overwinter mortality in yellow drum (Nibea albiflora): insights from growth and immune responses to cold and starvation stress. Fish & Shellfish Immunology, 92, pp.341-347.",2019,28,Yellow drum (Nibea albiflora),Nibea albiflora,Sciaenidae,Marine,Temperate,Y,https://www.fishbase.se/summary/Nibea-albiflora.html,16.8,24.7,7.9,Narrow,6 months ,Not stated,Not stated,Exp ,16,Below,8,Below,-8,Decrease,-8.8,-16.7,-8.8,"14 days, time course of response; taken day 14 as a snapshot",14,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Fe-SOD,0.5,Decrease,FALSE,Other,Starvation but data from fed control fish in all cases so diet not a counfounding factor,N,China,Aquaculture,4,2,427,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Unknown,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Song, H., Xu, D., Tian, L., Chen, R., Wang, L., Tan, P. and You, Q., 2019. Overwinter mortality in yellow drum (Nibea albiflora): insights from growth and immune responses to cold and starvation stress. Fish & Shellfish Immunology, 92, pp.341-347.",2019,28,Yellow drum (Nibea albiflora),Nibea albiflora,Sciaenidae,Marine,Temperate,Y,https://www.fishbase.se/summary/Nibea-albiflora.html,16.8,24.7,7.9,Narrow,6 months ,Not stated,Not stated,Exp ,16,Below,8,Below,-8,Decrease,-8.8,-16.7,-8.8,"14 days, time course of response; taken day 14 as a snapshot",14,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GPx,0.1,Decrease,FALSE,Other,Starvation but data from fed control fish in all cases so diet not a counfounding factor,N,China,Aquaculture,4,2,428,Chronic,NA,NA,,GPx,Peroxidase,Degradative enzyme,,Unknown,gpx1a,Unknown,gpx1a,GPX1,peroxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Song, H., Xu, D., Tian, L., Chen, R., Wang, L., Tan, P. and You, Q., 2019. Overwinter mortality in yellow drum (Nibea albiflora): insights from growth and immune responses to cold and starvation stress. Fish & Shellfish Immunology, 92, pp.341-347.",2019,28,Yellow drum (Nibea albiflora),Nibea albiflora,Sciaenidae,Marine,Temperate,Y,https://www.fishbase.se/summary/Nibea-albiflora.html,16.8,24.7,7.9,Narrow,6 months ,Not stated,Not stated,Exp ,16,Below,8,Below,-8,Decrease,-8.8,-16.7,-8.8,"14 days, time course of response; taken day 14 as a snapshot",14,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Mn-SOD,0.6,Decrease,FALSE,Other,Starvation but data from fed control fish in all cases so diet not a counfounding factor,N,China,Aquaculture,4,2,429,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Unknown,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,arg2a,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,430,Chronic,Chronic,10,,arg,Arginase,Arginase,,Unknown,arg2,Unknown,arg2,ARG2,hydrolase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,arg2a,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,431,Chronic,Chronic,10,,arg,Arginase,Arginase,,Unknown,arg2,Unknown,arg2,ARG2,hydrolase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,arg2b,0.6,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,432,Chronic,Chronic,10,,arg,Arginase,Arginase,,Unknown,arg2,Unknown,arg2,ARG2,hydrolase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,arg2b,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,433,Chronic,Chronic,10,,arg,Arginase,Arginase,,Unknown,arg2,Unknown,arg2,ARG2,hydrolase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,CD4,0.9,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,434,Chronic,Chronic,10,,CD4,T cell,T cell response,,Unknown,cd4-1,Unknown,cd4-1,CD4,immunoglobulin receptor superfamily,1,1,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,CD4,1.1,Increase,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,435,Chronic,Chronic,10,,CD4,T cell,T cell response,,Unknown,cd4-1,Unknown,cd4-1,CD4,immunoglobulin receptor superfamily,1,1,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,CD8a,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,436,Chronic,Chronic,10,,CD8,T cell,T cell response,,CD8A,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,CD8a,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,437,Chronic,Chronic,10,,CD8,T cell,T cell response,,CD8A,cd8a,Unknown,cd8a,CD8A,Unknown,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,CD8b,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,438,Chronic,Chronic,10,,CD8,T cell,T cell response,,CD8B,cd8b,Unknown,cd8b,CD8B,immunoglobulin receptor superfamily,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,CD8b,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,439,Chronic,Chronic,10,,CD8,T cell,T cell response,,CD8B,cd8b,Unknown,cd8b,CD8B,immunoglobulin receptor superfamily,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,HSP70,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,440,Chronic,Chronic,10,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,HSP70,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,441,Chronic,Chronic,10,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IgD,0.8,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,442,Chronic,Chronic,10,,IgD,Antibody,B cell response,,Unknown,ighd,Unknown,ighd,IGHD,immunoglobulin receptor superfamily,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IgD,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,443,Chronic,Chronic,10,,IgD,Antibody,B cell response,,Unknown,ighd,Unknown,ighd,IGHD,immunoglobulin receptor superfamily,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IgM-antigen specific,0.8,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,444,Chronic,Chronic,10,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IgM-antigen specific,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,445,Chronic,Chronic,10,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IgT,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,446,Chronic,Chronic,10,,IgT,Antibody,B cell response,,Unknown,Unknown,Unknown,IgT,IGH,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IgT,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,447,Chronic,Chronic,10,,IgT,Antibody,B cell response,,Unknown,Unknown,Unknown,IgT,IGH,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IL-4/IL-13A,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,448,Chronic,Chronic,10,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IL-4/IL-13A,0.6,Decrease,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,449,Chronic,Chronic,10,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IL-4/IL-13B,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,450,Chronic,Chronic,10,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IL-4/IL-13B,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,451,Chronic,Chronic,10,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,IL-4/IL-13B,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,452,Chronic,Chronic,10,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,iNOS,10,Increase,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,453,Chronic,Chronic,10,,iNOS,Degradative enzyme,Degradative enzyme,,Unknown,Unknown,nos1apa,nos1apa,NOS2,Unknown,1,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,MHC II,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,454,Chronic,Chronic,10,,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,MHC II,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,455,Chronic,Chronic,10,,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,Gill,Gene,MHC I,1,Same,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,456,Chronic,Chronic,10,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Benedicenti, O., Pottinger, T.G., Collins, C. and Secombes, C.J., 2019. Effects of temperature on amoebic gill disease development: Does it play a role?. Journal of fish diseases, 42(9), pp.1241-1258.",2019,29,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,not stated,Not stated,Not stated,Exp ,10,Above,15,Above,5,Increase,13,6,6,>10 days; 10 days of temp rise  prior to bacterial challenge. Time course but taking 10 days after bacteria as a snapshot,20,Time sample taken post temp first changed,Molecular ,qPCR,head kidney,Gene,MHC I,1.2,Increase,FALSE,Bacterial,Bacterial,Y,UK,Aquaculture,5,2,457,Chronic,Chronic,10,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,C3,1,Same,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,458,Chronic,Acute,0.5,,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g1-1,7,Increase,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,459,Chronic,Acute,0.5,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g1-2,2,Increase,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,460,Chronic,Acute,0.5,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-11,0.25,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,461,Chronic,Acute,0.5,,IL-11,IL-11,IL-12,,Unknown,il11a,Unknown,il11a,IL11,interleukin superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b1,0.25,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,462,Chronic,Acute,0.5,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b2,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,463,Chronic,Acute,0.5,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Lysozyme,0.2,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,464,Chronic,Acute,0.5,,Lysozyme,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Nfkbiab,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,465,Chronic,Acute,0.5,,NFkB,Intracellular signalling,Intracellular signalling,,unknown,nfkbiab,nfkbiab,nfkbiab,NFKB1,unknown,1,1,0,1,1,0,0,1,1,1,0,0,0,0,1,0,0,1,1,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,1,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,1,1,1,1,1,1,1,1,1,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-2,2,Increase,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,466,Chronic,Acute,0.5,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-3,2,Increase,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,467,Chronic,Acute,0.5,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TLR-9,1,Same,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,468,Chronic,Acute,0.5,,TLR-9,TLR pathway,PRR,,Unknown,tlr9,Unknown,tlr9,TLR9,transmembrane signal receptor,0,0,0,1,1,0,0,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a1,0.1,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,469,Chronic,Acute,0.5,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,Unknown,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Jiang, M., Chen, Z.G., Zheng, J. and Peng, B., 2019. Metabolites-enabled survival of crucian carps infected by Edwardsiella tarda in high water temperature. Frontiers in immunology, 10, p.1991.",2019,30,Crucian Carp,Carassius carassius,Cyprinidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Carassius-carassius.html,2,22,20,Wide,Not stated,Not stated,Not stated,Exp ,20,Within,30,Above,10,Increase,28,8,8,14 days prior to bacterial challenge. Assessed genes 12 hours post infection,14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a2,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Spain ,Unknown,not stated,not stated,470,Chronic,Acute,0.5,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,Unknown,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,10,Below,-20,Decrease,-4,-23,-4,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,0.9,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,471,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,15,Within,-15,Decrease,1,-18,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,0.6,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,472,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,20,Within,-10,Decrease,6,-13,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,0.5,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,473,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,25,Within,-5,Decrease,11,-8,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,0.7,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,474,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,10,Below,-20,Decrease,-4,-23,-4,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GSH-Px,0.5,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,475,Chronic,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,15,Within,-15,Decrease,1,-18,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GSH-Px,0.6,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,476,Chronic,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,20,Within,-10,Decrease,6,-13,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GSH-Px,0.5,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,477,Chronic,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,25,Within,-5,Decrease,11,-8,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,GSH-Px,0.7,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,478,Chronic,NA,NA,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,10,Below,-20,Decrease,-4,-23,-4,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA,2,Increase,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,479,Chronic,NA,NA,,MDA,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,15,Within,-15,Decrease,1,-18,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA,1.8,Increase,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,480,Chronic,NA,NA,,MDA,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,20,Within,-10,Decrease,6,-13,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA,1.2,Increase,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,481,Chronic,NA,NA,,MDA,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,25,Within,-5,Decrease,11,-8,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA,1,Same,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,482,Chronic,NA,NA,,MDA,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,10,Below,-20,Decrease,-4,-23,-4,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,1,Same,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,483,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,15,Within,-15,Decrease,1,-18,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,0.6,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,484,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,20,Within,-10,Decrease,6,-13,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,0.8,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,485,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 11/11/22,"Wu, F., Yang, C., Wen, H., Zhang, C., Jiang, M., Liu, W., Tian, J., Yu, L. and Lu, X., 2019. Improving low?temperature stress tolerance of tilapia, Oreochromis niloticus: A functional analysis of Astragalus membranaceus. Journal of the World Aquaculture Society, 50(4), pp.749-762.",2019,31,Tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Not stated,Not stated,Not stated,Exp ,30,Within,25,Within,-5,Decrease,11,-8,0,40 days,40,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,0.9,Decrease,FALSE,Chemical,AMEP (chinese herb in origin),N,China,Aquaculture,30,4,486,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,HSP70,1,Same,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,487,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,HSP70,0.8,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,488,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IFN-g,0.5,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,489,Chronic,NA,NA,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,4 weeks ,28,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IFN-g,0.3,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,490,Chronic,NA,NA,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-10,1,Same,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,491,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,28,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-10,1,Same,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,492,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-17,0.8,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,493,Chronic,NA,NA,,IL-17,Th2/17 pathway,Th2/17 pathway,,Unknown,il17a/f2,Unknown,il17a/f2,IL17A,Unknown,1,1,1,0,0,1,0,1,1,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-17,0.6,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,494,Chronic,NA,NA,,IL-17,Th2/17 pathway,Th2/17 pathway,,Unknown,il17a/f2,Unknown,il17a/f2,IL17A,Unknown,1,1,1,0,0,1,0,1,1,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-1b,0.7,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,495,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,5 weeks ,35,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-1b,1,Same,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,496,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-8,0.3,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,497,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,IL-8,0.2,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,498,Chronic,NA,NA,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,TGF-b,0.5,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,499,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,TGF-b,0.5,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,500,Chronic,NA,NA,,TGF-b,Th2/17 pathway,Th2/17 pathway,,Unknown,tgfb1a,Unknown,tgfb1a,TGFB1,growth factor,1,1,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,>6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,TNF-a,0.25,Decrease,FALSE,Other,Diet but comparing control diet against control diet here so not counfounding variable,N,Sweden ,Aquaculture,15,4,501,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Huyben, D., Vidakovic, A., Sundh, H., Sundell, K., Kiessling, A. and Lundh, T., 2019. Haematological and intestinal health parameters of rainbow trout are influenced by dietary live yeast and increased water temperature. Fish & Shellfish Immunology, 89, pp.525-536.",2019,32,Atlantic salmon (Salmo salar L.),Salmo salar,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Salmo-salar.html,2,9,7,Narrow,110g in weight,Juvenile,Not stated,Exp ,11,Above,18,Above,7,Increase,16,9,9,6 weeks ,42,Time sample taken post temp first changed,Molecular ,qPCR,Intestine,Gene,TNF-a,0.2,Decrease,FALSE,Probiotic,Y - comparing within challenge so not a factor,N,Sweden ,Aquaculture,15,4,502,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,"Difficult to work out when first feeding stage is; states day 8 (22c), day 10 (20C), day 12 (18C) and day 16 (16C) so matched to test temperature",Molecular ,qPCR,Larvae,Gene,C3,1.3,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,503,Chronic,NA,NA,On re-reading - amended as no viral challenge,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,C3,1.1,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,504,Chronic,NA,NA,On re-reading - amended as no viral challenge,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,C3,1.1,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,505,Chronic,NA,NA,On re-reading - amended as no viral challenge,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IgM-antigen specific,1.5,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,506,Chronic,NA,NA,On re-reading - amended as no viral challenge,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IgM-antigen specific,1.5,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,507,Chronic,NA,NA,On re-reading - amended as no viral challenge,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IgM-antigen specific,0.9,Decrease,FALSE,N,N,N,Germany,Aquaculture,30,2,508,Chronic,NA,NA,On re-reading - amended as no viral challenge,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IL-1b,0.8,Decrease,FALSE,N,N,N,Germany,Aquaculture,30,2,509,Chronic,NA,NA,On re-reading - amended as no viral challenge,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IL-1b,0.6,Decrease,FALSE,N,N,N,Germany,Aquaculture,30,2,510,Chronic,NA,NA,On re-reading - amended as no viral challenge,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,IL-1b,1.3,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,511,Chronic,NA,NA,On re-reading - amended as no viral challenge,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf3,1.2,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,512,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf3,1,Same,FALSE,N,N,N,Germany,Aquaculture,30,2,513,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf3,1.3,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,514,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf7,1.5,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,515,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf7,1,Same,FALSE,N,N,N,Germany,Aquaculture,30,2,516,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,irf7,0.9,Decrease,FALSE,N,N,N,Germany,Aquaculture,30,2,517,Chronic,NA,NA,On re-reading - amended as no viral challenge,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,lysc,2,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,518,Chronic,NA,NA,On re-reading - amended as no viral challenge,lysc,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,lysc,1.2,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,519,Chronic,NA,NA,On re-reading - amended as no viral challenge,lysc,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,lysc,2,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,520,Chronic,NA,NA,On re-reading - amended as no viral challenge,lysc,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,MHC II,2.2,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,521,Chronic,NA,NA,On re-reading - amended as no viral challenge,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,MHC II,1,Same,FALSE,N,N,N,Germany,Aquaculture,30,2,522,Chronic,NA,NA,On re-reading - amended as no viral challenge,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,MHC II,2.5,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,523,Chronic,NA,NA,On re-reading - amended as no viral challenge,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,16,Within,-4,Decrease,12,-4,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,16,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,TLR-2,0.9,Decrease,FALSE,N,N,N,Germany,Aquaculture,30,2,524,Chronic,NA,NA,On re-reading - amended as no viral challenge,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,18,Within,-2,Decrease,14,-2,0,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,12,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,TLR-2,1,Same,FALSE,N,N,N,Germany,Aquaculture,30,2,525,Chronic,NA,NA,On re-reading - amended as no viral challenge,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Miest, J.J., Politis, S.N., Adamek, M., Tomkiewicz, J. and Butts, I.A., 2019. Molecular ontogeny of larval immunity in European eel at increasing temperatures. Fish & shellfish immunology, 87, pp.105-119.",2019,33,European eel (Anguilla anguilla),Anguilla anguilla,Anguillidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Anguilla-anguilla.html,4,20,16,Wide,larval ,Larval,M,Exp ,20,Within,22,Above,2,Increase,18,2,2,until stage 3 life cycle (first feeding); not clear on tine but likely >3 days ,8,Difficult to work out when first feeding stage is,Molecular ,qPCR,Larvae,Gene,TLR-2,1.1,Increase,FALSE,N,N,N,Germany,Aquaculture,30,2,526,Chronic,NA,NA,On re-reading - amended as no viral challenge,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,C3,1.8,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,527,Chronic,Acute,1,,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,C3,1.3,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,528,Chronic,Chronic,4,,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,cathepsin L,1,Same,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,529,Chronic,Acute,1,,cathepsin L,Anti-microbial peptide/protein,Anti-microbial ,,unknown,ctsl.1,ctsl.1,ctsl.1,CTSL,cysteine protease,0,0,0,1,1,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,cathepsin L,2,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,530,Chronic,Chronic,4,,cathepsin L,Anti-microbial peptide/protein,Anti-microbial ,,unknown,ctsl.1,ctsl.1,ctsl.1,CTSL,cysteine protease,0,0,0,1,1,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,CFD,0.8,Decrease,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,531,Chronic,Acute,1,,CFD,Complement,Anti-microbial ,,CFD,cfd,Unknown,cfd,CFD,serine protease,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Not stated,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,CFD,5,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,532,Chronic,Chronic,4,,CFD,Complement,Anti-microbial ,,CFD,cfd,Unknown,cfd,CFD,serine protease,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Hepcidin,40,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,533,Chronic,Acute,1,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Hepcidin,2,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,534,Chronic,Chronic,4,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-1b,2,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,535,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-1b,0.6,Decrease,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,536,Chronic,Chronic,4,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-8,2.5,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,537,Chronic,Acute,1,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IL-8,1,Same,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,538,Chronic,Chronic,4,,IL-8,Chemokine,Chemokine,,Unknown,cxcl8a,Unknown,cxcl8a,CXCL8,Unknown,1,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,isg15,4,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,539,Chronic,Acute,1,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,isg15,1,Same,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,540,Chronic,Chronic,4,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA5,6,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,541,Chronic,Acute,1,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MDA5,2.6,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,542,Acute,Chronic,4,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MHC II,1,Same,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,543,Chronic,Acute,1,,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,MHC II,5,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,544,Chronic,Chronic,4,,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Mx,6,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,545,Chronic,Acute,1,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Mx,0.6,Decrease,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,546,Chronic,Chronic,4,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TLR-2,1.8,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,547,Chronic,Acute,1,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TLR-2,2,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,548,Chronic,Chronic,4,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 1 day post infection,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TLR-7,4,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,549,Chronic,Acute,1,,TLR-7,TLR pathway,PRR,,Unknown,tlr7,Unknown,tlr7,TLR7,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Kole, S., Avunje, S. and Jung, S.J., 2019. Differential expression profile of innate immune genes in the liver of olive flounder (Paralichthys olivaceus) against viral haemorrhagic septicaemia virus (VHSV) at host susceptible and non-susceptible temperatures. Aquaculture, 503, pp.51-58.",2019,34,Flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,18-22g,Juvenile,Not stated,Exp ,15,Within,20,Within,5,Increase,11.4,-5,0,7 days + 4 days post infection,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,TLR-7,1.2,Increase,FALSE,Viral,Viral,Y,Korea ,Aquaculture,5,not stated,550,Chronic,Chronic,4,,TLR-7,TLR pathway,PRR,,Unknown,tlr7,Unknown,tlr7,TLR7,Unknown,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Liu, F., Qu, Y.K., Wang, A.M., Yu, Y.B., Yang, W.P., Lv, F. and Nie, Q., 2019. Effects of carotenoids on the growth performance, biochemical parameters, immune responses and disease resistance of yellow catfish (Pelteobagrus fulvidraco) under high-temperature stress. Aquaculture, 503, pp.293-303.",2019,35, yellow catfish (Pelteobagrus fulvidraco) ,Pelteobagrus fulvidraco,Bagridae,Freshwater,Temperate,Y,https://www.fishbase.se/summary/Tachysurus-fulvidraco.html,16,25,9,Narrow,2.21g,Not stated,Not stated,Exp ,25,Within,32,Above,7,Increase,16,7,7,"one day, measurements at day 2",3,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Hepcidin,1.3,Increase,FALSE,Chemical,carotenoids but comparing controls so not a confounding factor,N,China ,Aquaculture,12,2,551,Chronic,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Liu, F., Qu, Y.K., Wang, A.M., Yu, Y.B., Yang, W.P., Lv, F. and Nie, Q., 2019. Effects of carotenoids on the growth performance, biochemical parameters, immune responses and disease resistance of yellow catfish (Pelteobagrus fulvidraco) under high-temperature stress. Aquaculture, 503, pp.293-303.",2019,35, yellow catfish (Pelteobagrus fulvidraco) ,Pelteobagrus fulvidraco,Bagridae,Freshwater,Temperate,Y,https://www.fishbase.se/summary/Tachysurus-fulvidraco.html,16,25,9,Narrow,2.21g,Not stated,Not stated,Exp ,25,Within,32,Above,7,Increase,16,7,7,"one day, measurements at day 2",3,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,HSP70,1.3,Increase,FALSE,Chemical,carotenoids but comparing controls so not a confounding factor,N,China ,Aquaculture,12,2,552,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Liu, F., Qu, Y.K., Wang, A.M., Yu, Y.B., Yang, W.P., Lv, F. and Nie, Q., 2019. Effects of carotenoids on the growth performance, biochemical parameters, immune responses and disease resistance of yellow catfish (Pelteobagrus fulvidraco) under high-temperature stress. Aquaculture, 503, pp.293-303.",2019,35, yellow catfish (Pelteobagrus fulvidraco) ,Pelteobagrus fulvidraco,Bagridae,Freshwater,Temperate,Y,https://www.fishbase.se/summary/Tachysurus-fulvidraco.html,16,25,9,Narrow,2.21g,Not stated,Not stated,Exp ,25,Within,32,Above,7,Increase,16,7,7,"one day, measurements at day 2",3,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,IgM-antigen specific,1.25,Increase,FALSE,Chemical,carotenoids but comparing controls so not a confounding factor,N,China ,Aquaculture,12,2,553,Chronic,NA,NA,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Liu, F., Qu, Y.K., Wang, A.M., Yu, Y.B., Yang, W.P., Lv, F. and Nie, Q., 2019. Effects of carotenoids on the growth performance, biochemical parameters, immune responses and disease resistance of yellow catfish (Pelteobagrus fulvidraco) under high-temperature stress. Aquaculture, 503, pp.293-303.",2019,35, yellow catfish (Pelteobagrus fulvidraco) ,Pelteobagrus fulvidraco,Bagridae,Freshwater,Temperate,Y,https://www.fishbase.se/summary/Tachysurus-fulvidraco.html,16,25,9,Narrow,2.21g,Not stated,Not stated,Exp ,25,Within,32,Above,7,Increase,16,7,7,"one day, measurements at day 2",3,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Lysozyme,2,Increase,FALSE,Chemical,carotenoids but comparing controls so not a confounding factor,N,China ,Aquaculture,12,2,554,Chronic,NA,NA,,Lysozyme,Degradative enzyme,Degradative enzyme,,Unknown,lyz,Unknown,lyz,LYZ,glycosidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Swirplies, F., Wuertz, S., Baßmann, B., Orban, A., Schäfer, N., Brunner, R.M., Hadlich, F., Goldammer, T. and Rebl, A., 2019. Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture, 501, pp.260-271.",2019,36,pikeperch Sander lucioperca,Sander lucioperca,Percidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Sander-lucioperca.html,6,22,16,Wide,8 week old ,Not stated,Not stated,Exp ,15,Within,25,Above,10,Increase,19,3,3,11 days ,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,C3,4,Increase,FALSE,NA,NA,NA,Germany,Aquaculture,33,3,555,Chronic,NA,NA,,C3,Complement,Anti-microbial ,,Unknown,c3a.1,Unknown,c3a.1,C3,Unknown,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Swirplies, F., Wuertz, S., Baßmann, B., Orban, A., Schäfer, N., Brunner, R.M., Hadlich, F., Goldammer, T. and Rebl, A., 2019. Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture, 501, pp.260-271.",2019,36,pikeperch Sander lucioperca,Sander lucioperca,Percidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Sander-lucioperca.html,6,22,16,Wide,8 week old ,Not stated,Not stated,Exp ,15,Within,25,Above,10,Increase,19,3,3,11 days ,11,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SAA,5,Increase,FALSE,NA,NA,NA,Germany,Aquaculture,33,3,556,Chronic,NA,NA,,SAA,Anti-microbial peptide/protein,Anti-microbial ,,SAA,saa,Unknown,saa,SAA1,Unknown,1,1,1,0,1,0,0,0,0,1,0,0,0,0,1,0,0,1,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Swirplies, F., Wuertz, S., Baßmann, B., Orban, A., Schäfer, N., Brunner, R.M., Hadlich, F., Goldammer, T. and Rebl, A., 2019. Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture, 501, pp.260-271.",2019,36,pikeperch Sander lucioperca,Sander lucioperca,Percidae,Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Sander-lucioperca.html,6,22,16,Wide,8 week old ,Not stated,Not stated,Exp ,15,Within,25,Above,10,Increase,19,3,3,11 days ,11,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,SerpinH1,4,Increase,FALSE,NA,NA,NA,Germany,Aquaculture,33,3,557,Chronic,NA,NA,,SerpinH1,Serine proteinase inhibitor,Serine proteinase inhibitor,,Unknown,serpinh1b,Unknown,serpinh1b,SERPINH1,protease inhibitor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1a,0.7,Decrease,FALSE,NA,NA,NA,China,Aquaculture,3,3,558,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1fma,Unknown,il1fma,IL1A,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1a,0.8,Decrease,FALSE,NA,NA,NA,China,Aquaculture,3,3,559,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1fma,Unknown,il1fma,IL1A,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1a,1.25,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,560,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1fma,Unknown,il1fma,IL1A,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1a,2,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,561,Acute,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1fma,Unknown,il1fma,IL1A,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1R,2,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,562,Acute,NA,NA,,IL-1R,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IL-1R,IL1R1,Unknown,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1R,0.8,Decrease,FALSE,NA,NA,NA,China,Aquaculture,3,3,563,Acute,NA,NA,,IL-1R,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IL-1R,IL1R1,Unknown,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1R,2,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,564,Acute,NA,NA,,IL-1R,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IL-1R,IL1R1,Unknown,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,IL-1R,1.7,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,565,Acute,NA,NA,,IL-1R,Inflammatory cytokine,Inflammatory cytokine,,Unknown,Unknown,Unknown,IL-1R,IL1R1,Unknown,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,MHC I,2.1,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,566,Acute,NA,NA,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,MHC I,2,Increase,FALSE,NA,NA,NA,China,Aquaculture,3,3,567,Acute,NA,NA,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,MHC I,1,Same,FALSE,NA,NA,NA,China,Aquaculture,3,3,568,Acute,NA,NA,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Sun, Z., Tan, X., Liu, Q., Ye, H., Zou, C., Xu, M., Zhang, Y. and Ye, C., 2019. Physiological, immune responses and liver lipid metabolism of orange-spotted grouper (Epinephelus coioides) under cold stress. Aquaculture, 498, pp.545-555.",2019,37,orange spotted grouper,Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,Not stated,Not stated,Not stated,Exp ,28,Within,19,Below,-9,Decrease,-5.4,-10.1,-5.4,24hours ,1,Time sample taken post temp first changed,Molecular ,qPCR,,Gene,MHC I,1,Same,FALSE,NA,NA,NA,China,Aquaculture,3,3,569,Acute,NA,NA,,MHC I,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc1zka,HLA-A,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Cellular,qPCR,Serum,Protein,Catalase,1,Same,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,570,Chronic,Chronic,28,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Cellular,qPCR,Serum,Protein,GSH-Px,1,Same,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,571,Chronic,Chronic,28,,GSH-Px,Peroxidase,Degradative enzyme,,Unknown,gss,Unknown,gss,GSS,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,HSP70,1.8,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,572,Chronic,Chronic,28,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,HSP70,2,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,573,Chronic,Chronic,28,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFN-g,0.8,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,574,Chronic,Chronic,28,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IFN-g,1.5,Increase,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,575,Chronic,Chronic,28,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,0.8,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,576,Chronic,Chronic,28,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,IL-1b,0.8,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,577,Chronic,Chronic,28,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Cellular,qPCR,Serum,Protein,MDA,1,Same,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,578,Chronic,Chronic,28,,MDA,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Cellular,qPCR,Serum,Protein,SOD,0.8,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,579,Chronic,Chronic,28,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular,qPCR,Spleen,Gene,TNF-a,0.8,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,580,Chronic,Chronic,28,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Wang, J., Lu, D.Q., Jiang, B., Luo, H.L., Lu, G.L. and Li, A.X., 2018. The effect of intermittent hypoxia under different temperature on the immunomodulation in Streptococcus agalactiae vaccinated Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 79, pp.181-192.",2018,38,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,Juvenile,Juvenile,Not stated,Exp ,30,Within,35,Above,5,Increase,21,2,2,14 days then sampled 28 days post vaccine,42,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney  ,Gene,TNF-a,0.9,Decrease,FALSE,Bacterial x Other,Bacterial x Vaccine,Y,China ,Aquaculture,3,4,581,Chronic,Chronic,28,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,HSP70,2,Increase,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,582,Chronic,Acute,1,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,HSP70,1,Same,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,583,Chronic,Acute,1,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,IL-1b,0.6,Decrease,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,584,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,585,Chronic,Acute,1,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,iNOS,1,Same,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,586,Chronic,Acute,1,,iNOS,Degradative enzyme,Degradative enzyme,,Unknown,Unknown,nos1apa,nos1apa,NOS2,Unknown,1,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,iNOS,0.3,Decrease,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,587,Chronic,Acute,1,,iNOS,Degradative enzyme,Degradative enzyme,,Unknown,Unknown,nos1apa,nos1apa,NOS2,Unknown,1,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,SOD1,3,Increase,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,588,Chronic,Acute,1,,SOD,SOD,Degradative enzyme,,SOD1,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,SOD1,2,Increase,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,589,Chronic,Acute,1,,SOD,SOD,Degradative enzyme,,SOD1,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Head kidney,Gene,TNF-a,1,Same,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,590,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 14/11/22,"Shahi, N., Ardó, L., Fazekas, G., Gócza, E., Kumar, S., Rèvèsz, N., Sándor, Z.J., Molnár, Z., Jeney, G. and Jeney, Z., 2018. Immunogene expression in head kidney and spleen of common carp (Cyprinus carpio L.) following thermal stress and challenge with Gram-negative bacterium, Aeromonas hydrophila. Aquaculture International, 26(3), pp.727-741.",2018,39,common carp (Cyprinus carpio L.),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,one year old,Juvenile,Not stated,Exp ,20,Within,30,Within,10,Increase,27,-5,0,"30 days , then back to 20C for bacterial challenge, sampled at 24hour post bacteria",31,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1,Same,FALSE,Bacterial,Bacterial,Y,Hungary ,Aquaculture,10,3,591,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Ammar, A.Y., El Nahas, A.F., Mahmoud, S., Barakat, M.E. and Hassan, A.M., 2018. Characterization of type IV antifreeze gene in Nile tilapia (Oreochromis niloticus) and influence of cold and hot weather on its expression and some immune-related genes. Fish physiology and biochemistry, 44(2), pp.515-525.",2018,40,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,200+/-10g,Juvenile,M,Exp ,14,Within,36,Above,22,Increase,22,3,3,"collected from pond, so would have been aclimated to either summer or winter months ",90,Assuming a season acclimation so 3 months,Molecular ,qPCR,spleen,Gene,cc-chemokine,2,Increase,FALSE,NA,NA,NA,Egypt ,Unknown,3,not stated,592,Chronic,NA,NA,,CC1,Chemokine,Chemokine,blast of primer shows CC1. CC-chemokine is a family of proteins. CCL19 GO terms used,unknown,unknown,,CC1,CCL14,unknown,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Ammar, A.Y., El Nahas, A.F., Mahmoud, S., Barakat, M.E. and Hassan, A.M., 2018. Characterization of type IV antifreeze gene in Nile tilapia (Oreochromis niloticus) and influence of cold and hot weather on its expression and some immune-related genes. Fish physiology and biochemistry, 44(2), pp.515-525.",2018,40,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,200+/-10g,Juvenile,M,Exp ,14,Within,36,Above,22,Increase,22,3,3,"collected from pond, so would have been aclimated to either summer or winter months ",90,Assuming a season acclimation so 3 months,Molecular ,qPCR,spleen,Gene,CXCL2,1.5,Increase,FALSE,NA,NA,NA,Egypt ,Unknown,3,not stated,593,Chronic,NA,NA,,CXCL2,Chemokine,Chemokine,,Unknown,Unknown,Unknown,CXCL2,CXCL2,Unknown,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Ammar, A.Y., El Nahas, A.F., Mahmoud, S., Barakat, M.E. and Hassan, A.M., 2018. Characterization of type IV antifreeze gene in Nile tilapia (Oreochromis niloticus) and influence of cold and hot weather on its expression and some immune-related genes. Fish physiology and biochemistry, 44(2), pp.515-525.",2018,40,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,200+/-10g,Juvenile,M,Exp ,14,Within,36,Above,22,Increase,22,3,3,"collected from pond, so would have been aclimated to either summer or winter months ",90,Assuming a season acclimation so 3 months,Molecular ,qPCR,spleen,Gene,IgMH,1.4,Increase,FALSE,NA,NA,NA,Egypt ,Unknown,3,not stated,594,Chronic,NA,NA,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgMH,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Ammar, A.Y., El Nahas, A.F., Mahmoud, S., Barakat, M.E. and Hassan, A.M., 2018. Characterization of type IV antifreeze gene in Nile tilapia (Oreochromis niloticus) and influence of cold and hot weather on its expression and some immune-related genes. Fish physiology and biochemistry, 44(2), pp.515-525.",2018,40,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,200+/-10g,Juvenile,M,Exp ,14,Within,36,Above,22,Increase,22,3,3,"collected from pond, so would have been aclimated to either summer or winter months ",90,Assuming a season acclimation so 3 months,Molecular ,qPCR,spleen,Gene,INF3A,3,Increase,FALSE,NA,NA,NA,Egypt ,Unknown,3,not stated,595,Chronic,NA,NA,,Type 1 IFN,Type I IFN,Anti-viral,(blast of primer shows interferon epsilon). Closest equivalent human gene provided,unknown,unknown,unknown,ifne,IFNA2,unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Ammar, A.Y., El Nahas, A.F., Mahmoud, S., Barakat, M.E. and Hassan, A.M., 2018. Characterization of type IV antifreeze gene in Nile tilapia (Oreochromis niloticus) and influence of cold and hot weather on its expression and some immune-related genes. Fish physiology and biochemistry, 44(2), pp.515-525.",2018,40,Nile tilapia (Oreochromis niloticus),Oreochromis niloticus,Cichlidae,Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Oreochromis-niloticus.html,14,33,19,Wide,200+/-10g,Juvenile,M,Exp ,14,Within,36,Above,22,Increase,22,3,3,"collected from pond, so would have been aclimated to either summer or winter months ",90,Assuming a season acclimation so 3 months,Molecular ,qPCR,spleen,Gene,MHC II,1.3,Increase,FALSE,NA,NA,NA,Egypt ,Unknown,3,not stated,596,Chronic,NA,NA,,MHC II,Ag processing and presentation,T cell response,,unknown,unknown,unknown,mhc2dga,HLA-DPA1,unknown,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,Catalase,1.2,Increase,FALSE,Chemical,astaxanthin in diet but comparing control groups so no influence of diet here,N,China ,Aquaculture,6,not stated,597,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,Catalase,2,Increase,FALSE,Chemical,40mg/kg astaxanthin,N,China ,Aquaculture,6,not stated,598,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,HSP70,2,Increase,FALSE,Chemical,astaxanthin in diet but comparing control groups so no influence of diet here,N,China ,Aquaculture,6,not stated,599,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,HSP70,1.5,Increase,FALSE,Chemical,40mg/kg astaxanthin,N,China ,Aquaculture,6,not stated,600,Acute,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,Mn-SOD,1,Same,FALSE,Chemical,astaxanthin in diet but comparing control groups so no influence of diet here,N,China ,Aquaculture,6,not stated,601,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Unknown,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Cheng, C.H., Guo, Z.X., Ye, C.X. and Wang, A.L., 2018. Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Fish physiology and biochemistry, 44(1), pp.209-218.",2018,41,pufferfish (Takifugu obscurus),Takifugu obscurus,Tetraodontidae,Marine + Freshwater + Brackish,Subtropical,NS,https://www.fishbase.se/summary/Takifugu-obscurus.html,NS,NS,NA,NA,not stated,Not stated,Not stated,Exp ,25,Below,34,Below,9,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,Mn-SOD,2,Increase,FALSE,Chemical,40mg/kg astaxanthin,N,China ,Aquaculture,6,not stated,602,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Unknown,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Catalase,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,603,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Catalase,2,Increase,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,604,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Cu/Zn-SOD,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,605,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Cu/Zn-SOD,1.6,Increase,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,606,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,HSP70,2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,20,4,607,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,HSP70,10,Increase,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,608,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-10,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,609,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-10,1,Same,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,610,Chronic,NA,NA,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,1.2,Increase,FALSE,NA,NA,NA,China ,Aquaculture,20,4,611,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,1,Same,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,612,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-6,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,613,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-6,2.8,Increase,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,614,Chronic,NA,NA,,IL-6,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il6,Unknown,il6,IL6,Unknown,1,1,1,1,0,0,0,1,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,iNOS,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,615,Chronic,NA,NA,,iNOS,Degradative enzyme,Degradative enzyme,,Unknown,Unknown,nos1apa,nos1apa,NOS2,Unknown,1,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,iNOS,1.8,Increase,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,616,Chronic,NA,NA,,iNOS,Degradative enzyme,Degradative enzyme,,Unknown,Unknown,nos1apa,nos1apa,NOS2,Unknown,1,1,1,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,MTs,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,617,Chronic,NA,NA,,MTs,Anti-oxidant,Anti-oxidant,,Unknown,mt2,Unknown,mt2,MT1A,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,MTs,0.5,Decrease,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,618,Chronic,NA,NA,,MTs,Anti-oxidant,Anti-oxidant,,Unknown,mt2,Unknown,mt2,MT1A,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,20,4,619,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhao, S.J., Guo, S.N., Zhu, Q.L., Yuan, S.S. and Zheng, J.L., 2018. Heat-induced oxidative stress and inflammation involve in cadmium pollution history in the spleen of zebrafish. Fish & Shellfish Immunology, 72, pp.1-8.",2018,42,Zebrafish ,Danio rerio,Danionidae,Freshwater,Tropical,N,https://www.fishbase.se/summary/Danio-rerio.html,18,24,6,Narrow,10 weeks,Adult,Equal ratio,Exp ,26,Above,32,Above,6,Increase,14,8,8,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1,Same,FALSE,Other,Cadium  5ug/ml,N,China ,Aquaculture,20,4,620,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,gp130,1.1,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,621,Chronic,Acute,1,,gp130,Inflammatory cytokine,Inflammatory cytokine,,unknown,il6st,unknown,il6st,IL6ST,unknown,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,gp130,3.5,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,622,Chronic,Acute,1,,gp130,Inflammatory cytokine,Inflammatory cytokine,,unknown,il6st,unknown,il6st,IL6ST,unknown,1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,il6r,8,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,623,Chronic,Acute,1,,il6r,Inflammatory cytokine,Inflammatory cytokine,,IL6R,il6r,Unknown,il6r,IL6R,transmembrane signal receptor,1,1,1,1,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,il6r,1.7,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,624,Chronic,Acute,1,,il6r,Inflammatory cytokine,Inflammatory cytokine,,IL6R,il6r,Unknown,il6r,IL6R,transmembrane signal receptor,1,1,1,1,0,0,0,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,irf3,2,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,625,Chronic,Acute,1,,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,irf3,1.2,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,626,Chronic,Acute,1,,irf3,Anti-viral signalling,PRR,,IRF3,irf3,Unknown,irf3,IRF3,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,1,1,0,1,0,0,0,1,1,0,0,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,irf7,1.2,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,627,Chronic,Acute,1,,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,irf7,1.3,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,628,Chronic,Acute,1,,irf7,Anti-viral signalling,PRR,,IRF7,irf7,Unknown,irf7,IRF7,winged helix/forkhead transcription factor,1,0,0,1,1,1,1,1,1,1,1,0,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,1,1,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-2,5,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,629,Chronic,Acute,1,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-2,2.5,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,630,Chronic,Acute,1,,TLR-2,TLR pathway,PRR,,Unknown,tlr2,Unknown,tlr2,TLR2,transmembrane signal receptor,0,0,0,1,1,1,0,1,1,1,1,0,1,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-21,2.5,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,631,Chronic,Acute,1,,TLR-21,TLR pathway,PRR,no human homolog but most similar in ligand binding (and phylogenetics) to TLR3,unknown,tlr21,tlr21,tlr21,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-21,1.3,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,632,Chronic,Acute,1,,TLR-21,TLR pathway,PRR,no human homolog but most similar in ligand binding (and phylogenetics) to TLR3,unknown,tlr21,tlr21,tlr21,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-22,3,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,633,Chronic,Acute,1,,TLR-22,TLR pathway,PRR,no human homolog but most similar to TLR3 in ligand binidng and phylogenetics,unknown,tlr22,tlr22,tlr22,TLR3,scaffold/adaptor protein,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-22,2,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,634,Chronic,Acute,1,,TLR-22,TLR pathway,PRR,no human homolog but most similar to TLR3 in ligand binidng and phylogenetics,unknown,tlr22,tlr22,tlr22,TLR3,scaffold/adaptor protein,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-3,2,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,635,Chronic,Acute,1,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-3,1.3,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,636,Chronic,Acute,1,,TLR-3,TLR pathway,PRR,,Unknown,tlr3,Unknown,tlr3,TLR3,transmembrane signal receptor,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-5l,1,Same,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,637,Chronic,Acute,1,,TLR-5,TLR pathway,PRR,,Unknown,tlr5a,Unknown,tlr5a,TLR5,Unknown,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TLR-5l,2,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,638,Chronic,Acute,1,,TLR-5,TLR pathway,PRR,,Unknown,tlr5a,Unknown,tlr5a,TLR5,Unknown,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos fresh water,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TNF-a,3,Increase,FALSE,Chemical x Other,LPS x Freshwater,N,Taiwan,Aquaculture,6,not stated,639,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Chang, C.H., Lin, J.Y., Lo, W.Y. and Lee, T.H., 2017. Hypothermal stress induced differential expression profiles of the immune response gene, warm-temperature-acclimation associated 65-kDa protein (Wap65), in the liver of fresh water and seawater milkfish, Chanos chanos. Fish & Shellfish Immunology, 70, pp.174-184.",2017,43,Milkfish chanos chanos  seawater,Chanos chanos,Chanidae,Marine + Freshwater + Brackish,Tropical,N,https://www.fishbase.se/summary/Chanos-chanos.html,15,43,28,Wide,Juvenile,Juvenile,Not stated,Exp ,28,Within,18,Within,-10,Decrease,3,-25,0,168h +24 hours post LPS but not v clear,8,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,TNF-a,4,Increase,FALSE,Chemical x Other,LPS x Saltwater,N,Taiwan,Aquaculture,6,not stated,640,Chronic,Acute,1,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"6 week , 12 hours post infection (time course but taking peak)",42.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,1.3,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,641,Chronic,Acute,12,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"6 week , 12 hours post infection (time course but taking peak)",42.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IL-1b,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,642,Chronic,NA,NA,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"3 week , 12 hours post infection (time course but taking peak)",21.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,isg15,40,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,643,Chronic,Acute,12,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"3 week , 12 hours post infection (time course but taking peak)",21.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,isg15,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,644,Chronic,NA,NA,,isg15,RLR pathway,PRR,,ISG15,isg15,Unknown,isg15,ISG15,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"4 week , 12 hours post infection (time course but taking peak)",28.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,MDA5,10,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,645,Chronic,Acute,12,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"4 week , 12 hours post infection (time course but taking peak)",28.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,MDA5,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,646,Chronic,NA,NA,,MDA5,RLR pathway,PRR,,Unknown,ifih1,Unknown,ifih1,IFIH1,Unknown,0,0,0,0,1,1,0,1,1,0,1,0,1,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"2 week , 12 hours post infection (time course but taking peak)",14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Mx,16,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,647,Chronic,Acute,12,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"2 week , 12 hours post infection (time course but taking peak)",14.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,Mx,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,648,Chronic,NA,NA,,Mx,RLR,PRR,,Unknown,mxa,Unknown,mxa,MX1,membrane traffic protein,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"5 week , 12 hours post infection (time course but taking peak)",35.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1.2,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,649,Chronic,Acute,12,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"5 week , 12 hours post infection (time course but taking peak)",35.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,TNF-a,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,650,Chronic,NA,NA,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,TNFA,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"1 week , 12 hours post infection (time course but taking peak)",7.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFNI,50,Increase,FALSE,Viral,Viral,Y,China ,Aquaculture,5,not stated,651,Chronic,Acute,12,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Zhang, J., Tang, X., Sheng, X., Xing, J. and Zhan, W., 2017. The influence of temperature on viral replication and antiviral-related genes response in hirame rhabdovirus-infected flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 68, pp.260-265.",2017,44,flounder (Paralichthys olivaceus),Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,not stated,Not stated,Not stated,Exp ,10,Within,20,Within,10,Increase,11.4,-5,0,"1 week , 12 hours post infection (time course but taking peak)",7.5,Time sample taken post temp first changed,Molecular ,qPCR,Spleen,Gene,IFNI,1,Same,FALSE,NA,NA,NA,China ,Aquaculture,5,not stated,652,Chronic,NA,NA,,Type 1 IFN,Type I IFN,Anti-viral,,Unknown,ifnphi1,Unknown,ifnphi1,IFNA1,Unknown,1,0,0,1,1,1,1,1,1,0,1,0,1,1,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Yu, H., Deng, W., Zhang, D., Gao, Y., Yang, Z., Shi, X., Sun, J., Zhou, J. and Ji, H., 2017. Antioxidant defenses of Onychostoma macrolepis in response to thermal stress: insight from mRNA expression and activity of superoxide dismutase and catalase. Fish & Shellfish Immunology, 66, pp.50-61.",2017,45,Onychostoma macrolepis,Onychostoma macrolepis,Cyprinidae,Freshwater,Subtropical,NS,https://www.fishbase.se/summary/Onychostoma-macrolepis.html,NS,NS,NA,NA,Not stated,Not stated,Not stated,Exp ,24,Below,30,Below,6,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Multiple tissues analysed separately; data for spleen only,Gene,Catalase,3,Increase,FALSE,NA,NA,NA,China ,Aquaculture,3,3,653,Acute,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Yu, H., Deng, W., Zhang, D., Gao, Y., Yang, Z., Shi, X., Sun, J., Zhou, J. and Ji, H., 2017. Antioxidant defenses of Onychostoma macrolepis in response to thermal stress: insight from mRNA expression and activity of superoxide dismutase and catalase. Fish & Shellfish Immunology, 66, pp.50-61.",2017,45,Onychostoma macrolepis,Onychostoma macrolepis,Cyprinidae,Freshwater,Subtropical,NS,https://www.fishbase.se/summary/Onychostoma-macrolepis.html,NS,NS,NA,NA,Not stated,Not stated,Not stated,Exp ,24,Below,30,Below,6,Increase,NA,NA,NA,48hours ,2,Time sample taken post temp first changed,Molecular ,qPCR,Multiple tissues analysed separately; data for spleen only,Gene,SOD,3,Increase,FALSE,NA,NA,NA,China ,Aquaculture,3,3,654,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,Blimp1,30,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,655,Chronic,Chronic,42,,Blimp1,B cell regulator,B cell response,,Unknown,prdm1a,Unknown,prdm1a,PRDM1,C2H2 zinc finger transcription factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,GATA3,1,Same,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,656,Chronic,Chronic,42,,GATA3,Th2 driver,Th2/17 pathway,,GATA3,gata3,Unknown,gata3,GATA3,DNA-binding transcription factor,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,IFN-g,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,657,Chronic,Chronic,42,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,IgM-antigen specific,5,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,658,Chronic,Chronic,42,,IgM,Antibody,B cell response,,Unknown,Unknown,Unknown,IgM-antigen specific,IGHM,Unknown,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,IgT,2,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,659,Chronic,Chronic,42,,IgT,Antibody,B cell response,,Unknown,Unknown,Unknown,IgT,IGH,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,IL-10,5,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,660,Chronic,Chronic,42,,IL-10,Immunoregulatory cytokine,Immunoregulatory cytokine,,Unknown,il10,Unknown,il10,IL10,Unknown,1,1,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,IL-4/IL-13A,2,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,661,Chronic,Chronic,42,,IL-4/IL-13,Th2/17 pathway,Th2/17 pathway,,Unknown,il4,Unknown,il4,IL4,Unknown,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,Pax5,10,Increase,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,662,Chronic,Chronic,42,,Pax5,B cell regulator,B cell response,,PAX5,pax5,Unknown,pax5,PAX5,homeodomain transcription factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,Tbet,0.3,Decrease,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,663,Chronic,Chronic,42,,Tbet,T cell driver,T cell response,,Unknown,tbx21,Unknown,tbx21,TBX21,Rel homology transcription factor,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 15/11/22,"Bailey, C., Segner, H., Casanova-Nakayama, A. and Wahli, T., 2017. Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease. Fish & shellfish immunology, 63, pp.424-437.",2017,46,rainbow trout,Oncorhynchus mykiss,Salmonidae,Marine + Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Oncorhynchus-mykiss.html,10,24,14,Wide,Not stated,Not stated,F,Exp ,12,Within,15,Within,3,Increase,5,-9,0,6 weeks post infection,42,Time sample taken post temp first changed,Molecular ,qPCR,kidney,Gene,TNFa 1+2,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Switzerland,Aquaculture,6,not stated,664,Chronic,Chronic,42,,TNF-a,Inflammatory cytokine,Inflammatory cytokine,,Unknown,tnfa,Unknown,tnfa,TNF,intercellular signal molecule,1,1,1,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 6 hours post injection with bacteria. Time course but this is peak,7.25,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,ERAP2,2,Increase,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,665,Chronic,Acute,0.25,,ERAP2,Ag processing and presentation,T cell response,,ERAP2,erap2,Unknown,erap2,ERAP2,metalloprotease,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,ERAP2,1,Same,FALSE,N ,NA,N,Japan,Aquaculture,5,not stated,666,Chronic,NA,NA,,ERAP2,Ag processing and presentation,T cell response,,ERAP2,erap2,Unknown,erap2,ERAP2,metalloprotease,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 6 hours post injection with bacteria. Time course but this is peak,7.5,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,Hepcidin,4,Increase,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,667,Chronic,Acute,0.25,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 3 hours post injection with bacteria. Time course but this is peak,7.125,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IFN-g,32,Increase,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,668,Chronic,Acute,0.125,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 6 hours post injection with bacteria. Time course but this is peak,7.25,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IFN-g,1,Same,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,669,Chronic,Acute,0.25,,IFN-g,Inflammatory cytokine,Inflammatory cytokine,,Unknown,ifng1,Unknown,ifng1,IFNG,interferon superfamily,1,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 3 hours post injection with bacteria. Time course but this is peak,7.125,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IL-1b,4,Increase,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,670,Chronic,Acute,0.125,,IL-1 ,Inflammatory cytokine,Inflammatory cytokine,,Unknown,il1b,Unknown,il1b,IL1B,interleukin superfamily,1,1,1,1,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 6 hours post injection with bacteria. Time course but this is peak,7.25,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IRF-1,0.5,Decrease,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,671,Chronic,Acute,0.25,,IRF-1,Anti-viral signalling,PRR,,Unknown,irf1a,Unknown,irf1a,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days+ 6 hours post injection with bacteria. Time course but this is peak,7.25,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IRF-10,10,Increase,FALSE,Bacterial,Bacterial,Y,Japan,Aquaculture,5,not stated,672,Chronic,Acute,0.25,,IRF-10,Anti-viral signalling,PRR,,Unknown,irf10,Unknown,irf10,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Kaneshige, N., Jirapongpairoj, W., Hirono, I. and Kondo, H., 2016. Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells. Fish & Shellfish Immunology, 59, pp.298-304.",2016,47,Japanese flounder Paralichthys olivaceus,Paralichthys olivaceus,Paralichthyidae,Marine,Subtropical,Y,https://www.fishbase.se/summary/Paralichthys-olivaceus.html,8.6,25,16.4,Wide,10cm total length,Juvenile,Not stated,Exp ,15,Within,22,Within,7,Increase,13.4,-3,0,7 days ,7,Time sample taken post temp first changed,Molecular ,qPCR,spleen,Gene,IRF-10,1,Same,FALSE,N,NA,Y,Japan,Aquaculture,5,not stated,673,Chronic,NA,NA,,IRF-10,Anti-viral signalling,PRR,,Unknown,irf10,Unknown,irf10,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Jung, S.J., Choi, Y.J., Kim, N.N., Choi, J.Y., Kim, B.S. and Choi, C.Y., 2016. Effects of melatonin injection or green-wavelength LED light on the antioxidant system in goldfish (Carassius auratus) during thermal stress. Fish & Shellfish Immunology, 52, pp.157-166.",2016,48,goldfish (Carassius auratus),Carassius auratus,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Carassius-auratus.html,0,41,41,Wide,12cm,Not stated,Not stated,Exp ,22,Within,30,Within,8,Increase,30,-11,0,4 days to reach temp and then up to 24 hours post melatonin,5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,Catalase,3,Increase,FALSE,Chemical x Other,Melatonin but comparing controls x Wavelength,N,Korea ,Aquaculture,27,not stated,674,Chronic,NA,NA,,Catalase,Anti-oxidant,Anti-oxidant,,Unknown,cat,Unknown,cat,CAT,peroxidase,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Jung, S.J., Choi, Y.J., Kim, N.N., Choi, J.Y., Kim, B.S. and Choi, C.Y., 2016. Effects of melatonin injection or green-wavelength LED light on the antioxidant system in goldfish (Carassius auratus) during thermal stress. Fish & Shellfish Immunology, 52, pp.157-166.",2016,48,goldfish (Carassius auratus),Carassius auratus,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Carassius-auratus.html,0,41,41,Wide,12cm,Not stated,Not stated,Exp ,22,Within,30,Within,8,Increase,30,-11,0,4 days to reach temp and then up to 24 hours post melatonin,5,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,SOD,3,Increase,FALSE,Chemical x Other,Melatonin but comparing controls x Wavelength,N,Korea ,Aquaculture,27,not stated,675,Chronic,NA,NA,,SOD,SOD,Degradative enzyme,,Unknown,sod1,Unknown,sod1,SOD1,Oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Liu, B., Xu, P., Brown, P.B., Xie, J., Ge, X., Miao, L., Zhou, Q., Ren, M. and Pan, L., 2016. The effect of hyperthermia on liver histology, oxidative stress and disease resistance of the Wuchang bream, Megalobrama amblycephala. Fish & Shellfish Immunology, 52, pp.317-324.",2016,49,Wuchang bream (Megalobrama amblycephala),Megalobrama amblycephala,Xenocyprididae,Freshwater,Temperate,N,https://www.fishbase.se/summary/Megalobrama-amblycephala.html,10,20,10,NA,77g,Not stated,Not stated,Exp ,25,Above,32,Above,7,Increase,22,12,12,24 hours,1,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,HSP70,10,Increase,FALSE,Viral,Viral,Y,China,Aquaculture,15,3,676,Acute,Acute,1,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Huang, J.F., Xu, Q.Y. and Chang, Y.M., 2015. Effects of temperature and dietary protein on gene expression of Hsp70 and Wap65 and immunity of juvenile mirror carp (C yprinus carpio). Aquaculture Research, 46(11), pp.2776-2788.",2015,50,Mirror carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,18,Within,23,Within,5,Increase,20,-12,0,60 days ,60,Time sample taken post temp first changed,Molecular ,qPCR,Brain,Gene,HSP70,0.2,Decrease,FALSE,Other,Protein diet - comparing low protein groups in every case,N,China ,Aquaculture,6,5,677,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Huang, J.F., Xu, Q.Y. and Chang, Y.M., 2015. Effects of temperature and dietary protein on gene expression of Hsp70 and Wap65 and immunity of juvenile mirror carp (C yprinus carpio). Aquaculture Research, 46(11), pp.2776-2788.",2015,50,Mirror carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,18,Within,28,Within,10,Increase,25,-7,0,60 days ,60,Time sample taken post temp first changed,Molecular ,qPCR,Brain,Gene,HSP70,0.6,Decrease,FALSE,Other,Protein diet - comparing low protein groups in every case,N,China ,Aquaculture,6,5,678,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Huang, J.F., Xu, Q.Y. and Chang, Y.M., 2015. Effects of temperature and dietary protein on gene expression of Hsp70 and Wap65 and immunity of juvenile mirror carp (C yprinus carpio). Aquaculture Research, 46(11), pp.2776-2788.",2015,50,Mirror carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,18,Within,23,Within,5,Increase,20,-12,0,60 days ,60,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,HSP70,0.1,Decrease,FALSE,Other,Protein diet - comparing low protein groups in every case,N,China ,Aquaculture,6,5,679,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Huang, J.F., Xu, Q.Y. and Chang, Y.M., 2015. Effects of temperature and dietary protein on gene expression of Hsp70 and Wap65 and immunity of juvenile mirror carp (C yprinus carpio). Aquaculture Research, 46(11), pp.2776-2788.",2015,50,Mirror carp (Cyprinus carpio),Cyprinus carpio,Cyprinidae,Freshwater + Brackish,Subtropical,N,https://www.fishbase.se/summary/Cyprinus-carpio.html,3,35,32,Wide,Juvenile ,Juvenile,Not stated,Exp ,18,Within,28,Within,10,Increase,25,-7,0,60 days ,60,Time sample taken post temp first changed,Molecular ,qPCR,Liver,Gene,HSP70,0.3,Decrease,FALSE,Other,Protein diet - comparing low protein groups in every case,N,China ,Aquaculture,6,5,680,Chronic,NA,NA,,HSP70,Heat stress,Heat stress,,Unknown,hsp70.1,Unknown,hsp70.1,HSPA4,Hsp70 family chaperone,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,Cath1,3,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,681,Chronic,NA,NA,,camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,CATH-1a,CATH-1a,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Skin,Gene,Cath1,3,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,682,Chronic,NA,NA,,camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,CATH-1a,CATH-1a,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Rectum,Gene,Cath1,1,Same,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,683,Chronic,NA,NA,,camp,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,CATH-1a,CATH-1a,CAMP,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,Defb,5,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,684,Chronic,NA,NA,,Defb,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,defbl1,defbl1,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Skin,Gene,Defb,1.2,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,685,Chronic,NA,NA,,Defb,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,defbl1,defbl1,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,Hepcidin,5,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,686,Chronic,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Skin,Gene,Hepcidin,3,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,687,Chronic,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Rectum,Gene,Hepcidin,3,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,688,Chronic,NA,NA,,Hepcidin,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,hamp,Unknown,hamp,HAMP,Unknown,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,Pis1,2.5,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,689,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis1,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Skin,Gene,Pis1,2,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,690,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis1,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Rectum,Gene,Pis1,1,Same,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,691,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis1,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Gills,Gene,Pis2,1,Same,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,692,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis2,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Skin,Gene,Pis2,1,Same,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,693,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis2,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 16/11/22,"Ruangsri, J., Lokesh, J., Fernandes, J.M. and Kiron, V., 2014. Transcriptional regulation of antimicrobial peptides in mucosal tissues of Atlantic cod Gadus morhua L. in response to different stimuli. Aquaculture Research, 45(12), pp.1893-1905.",2014,51,Atlantic cod (Gadus morhua),Gadus morhua,Gadidae,Marine + Brackish,Temperate,N,https://www.fishbase.se/summary/Gadus-morhua.html,0,15,15,Wide,Juvenile ,Juvenile,Not stated,Exp ,4,Within,12,Within,8,Increase,12,-3,0,72h,3,Time sample taken post temp first changed,Molecular ,qPCR,Rectum,Gene,Pis2,5,Increase,FALSE,NA,NA,NA,Norway ,Aquaculture,6,not stated,694,Chronic,NA,NA,,Pis,Anti-microbial peptide/protein,Anti-microbial ,,Unknown,Unknown,Unknown,Pis2,DEFB1,Unknown,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,small fish spleen,Gene,IRF-1,1.4,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,695,Chronic,Chronic,42,,IRF-1,Anti-viral signalling,PRR,,Unknown,irf1a,Unknown,irf1a,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,larger fish spleen,Gene,IRF-1,1.8,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,696,Chronic,Chronic,42,,IRF-1,Anti-viral signalling,PRR,,Unknown,irf1a,Unknown,irf1a,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,small fish skin,Gene,IRF-1,0.3,Decrease,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,697,Chronic,Chronic,42,,IRF-1,Anti-viral signalling,PRR,,Unknown,irf1a,Unknown,irf1a,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,larger fish skin,Gene,IRF-1,0.3,Decrease,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,698,Chronic,Chronic,42,,IRF-1,Anti-viral signalling,PRR,,Unknown,irf1a,Unknown,irf1a,IRF1,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,small fish spleen,Gene,IRF-2,2,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,699,Chronic,Chronic,42,,IRF-2,Anti-viral signalling,PRR,,Unknown,irf2,Unknown,irf2,IRF2,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,larger fish spleen,Gene,IRF-2,5,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,700,Chronic,Chronic,42,,IRF-2,Anti-viral signalling,PRR,,Unknown,irf2,Unknown,irf2,IRF2,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,small fish skin,Gene,IRF-2,2,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,701,Chronic,Chronic,42,,IRF-2,Anti-viral signalling,PRR,,Unknown,irf2,Unknown,irf2,IRF2,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Gradil, A.M., Wright, G.M., Speare, D.J., Wadowska, D.W., Purcell, S. and Fast, M.D., 2014. The effects of temperature and body size on immunological development and responsiveness in juvenile shortnose sturgeon (Acipenser brevirostrum). Fish & Shellfish Immunology, 40(2), pp.545-555.",2014,52,Shortnose sturgeon (Acipenser brevirostrum),Acipenser brevirostrum,Acipenseridae,Marine + Freshwater + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Acipenser-brevirostrum.html,7.5,25.5,18,Wide,Juvenile (7 month) ,Juvenile,Not stated,Exp ,11,Within,20,Within,9,Increase,12.5,-5.5,0,6 weeks,42,Time sample taken post temp first changed,Molecular ,qPCR,larger fish skin,Gene,IRF-2,1.6,Increase,FALSE,Other,Parasite,Y,Canada ,Aquaculture,30,2,702,Chronic,Chronic,42,,IRF-2,Anti-viral signalling,PRR,,Unknown,irf2,Unknown,irf2,IRF2,winged helix/forkhead transcription factor,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Anttila, K., Eliason, E.J., Kaukinen, K.H., Miller, K.M. and Farrell, A.P., 2014. Facing warm temperatures during migration: cardiac mRNA responses of two adult Oncorhynchus nerka populations to warming and swimming challenges. Journal of Fish Biology, 84(5), pp.1439-1456.",2014,53,Sockeye salmon (Oncorhynchus nerka),Oncorhynchus nerka,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Oncorhynchus-nerka.html,0,25,25,Wide,adult ,Adult,Not stated,Exp ,12,Within,18,Within,6,Increase,18,-7,0,3-4 days,3.5,Time sample taken post temp first changed,Molecular ,qPCR,ventricle,Gene,COX3,1,Same,FALSE,Other,swimming challenge,N,Canada and Finland,Wild,6,not stated ,703,Chronic,NA,NA,,COX3,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX3,mt-co3,COX3,COX3,COX3,oxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Anttila, K., Eliason, E.J., Kaukinen, K.H., Miller, K.M. and Farrell, A.P., 2014. Facing warm temperatures during migration: cardiac mRNA responses of two adult Oncorhynchus nerka populations to warming and swimming challenges. Journal of Fish Biology, 84(5), pp.1439-1456.",2014,53,Sockeye salmon (Oncorhynchus nerka),Oncorhynchus nerka,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Oncorhynchus-nerka.html,0,25,25,Wide,adult ,Adult,Not stated,Exp ,12,Within,18,Within,6,Increase,18,-7,0,3-4 days,3.5,Time sample taken post temp first changed,Molecular ,qPCR,ventricle,Gene,COX3,0.8,Decrease,FALSE,Other,resting,N,Canada and Finland,Wild,6,not stated ,704,Chronic,NA,NA,,COX3,Eicosanoid sythesis,Eicosanoid synthesis,matches used including COX4I1,COX3,mt-co3,COX3,COX3,COX3,oxidase,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Anttila, K., Eliason, E.J., Kaukinen, K.H., Miller, K.M. and Farrell, A.P., 2014. Facing warm temperatures during migration: cardiac mRNA responses of two adult Oncorhynchus nerka populations to warming and swimming challenges. Journal of Fish Biology, 84(5), pp.1439-1456.",2014,53,Sockeye salmon (Oncorhynchus nerka),Oncorhynchus nerka,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Oncorhynchus-nerka.html,0,25,25,Wide,adult ,Adult,Not stated,Exp ,12,Within,18,Within,6,Increase,18,-7,0,3-4 days,3.5,Time sample taken post temp first changed,Molecular ,qPCR,ventricle,Gene,iip,2,Increase,FALSE,Other,swimming challenge,N,Canada and Finland,Wild,6,not stated ,705,Chronic,NA,NA,,iip,RLR,PRR,,Unknown,ifit8,Unknown,ifit8,IFIT3,defense/immunity protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Anttila, K., Eliason, E.J., Kaukinen, K.H., Miller, K.M. and Farrell, A.P., 2014. Facing warm temperatures during migration: cardiac mRNA responses of two adult Oncorhynchus nerka populations to warming and swimming challenges. Journal of Fish Biology, 84(5), pp.1439-1456.",2014,53,Sockeye salmon (Oncorhynchus nerka),Oncorhynchus nerka,Salmonidae,Marine + Freshwater + Brackish,Temperate,N,https://www.fishbase.se/summary/Oncorhynchus-nerka.html,0,25,25,Wide,adult ,Adult,Not stated,Exp ,12,Within,18,Within,6,Increase,18,-7,0,3-4 days,3.5,Time sample taken post temp first changed,Molecular ,qPCR,ventricle,Gene,iip,3,Increase,FALSE,Other,resting,N,Canada and Finland,Wild,6,not stated ,706,Chronic,NA,NA,,iip,RLR,PRR,,Unknown,ifit8,Unknown,ifit8,IFIT3,defense/immunity protein,1,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,20,Below,-5,Decrease,-4.4,-9.1,-4.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,1,Same,FALSE,Other,Control diet,N,China ,Aquaculture,6,3,707,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,15,Below,-10,Decrease,-9.4,-14.1,-9.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,1,Same,FALSE,Other,Control diet,N,China ,Aquaculture,6,3,708,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,10,Below,-15,Decrease,-14.4,-19.1,-14.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,1,Same,FALSE,Other,Control diet,N,China ,Aquaculture,6,3,709,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,20,Below,-5,Decrease,-4.4,-9.1,-4.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,0.5,Decrease,FALSE,Other,FABP10 additive,N,China ,Aquaculture,6,3,710,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,15,Below,-10,Decrease,-9.4,-14.1,-9.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,2.1,Increase,FALSE,Other,FABP10 additive,N,China ,Aquaculture,6,3,711,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
Yes 17/11/22,"Luo, S.W., Cai, L., Liu, Y. and Wang, W.N., 2014. Functional analysis of a dietary recombinant Fatty acid binding protein 10 (FABP10) on the Epinephelus coioides in response to acute low temperature challenge. Fish & shellfish immunology, 36(2), pp.475-484.",2014,54,Orange-spotted grouper (Epinephelus coioides),Epinephelus coioides,Serranidae,Marine + Brackish,Subtropical,Y,https://www.fishbase.se/summary/Epinephelus-coioides.html,24.4,29.1,4.7,Narrow,weight 7.76g,Juvenile,Not stated,Exp ,25,Within,10,Below,-15,Decrease,-14.4,-19.1,-14.4,3 hours ,0.125,Time sample taken post temp first changed,Molecular ,qPCR,Liver  ,Gene,SOD2,1.6,Increase,FALSE,Other,FABP10 additive,N,China ,Aquaculture,6,3,712,Acute,NA,NA,,SOD,SOD,Degradative enzyme,,SOD2,sod2,Unknown,sod2,SOD2,oxidoreductase,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0