Study,ID,Title,StressorTwoCategory,StressorTwoSubcategory,StressorTwo,StressorTwoLevels,Duration,ResponseDefined,Response,ResponseUnits,Response.category,Combination,Top.3.response,StressorOneLevels,StressorOneUnits,StressorTwoUnits,TimeSeries,Treatmentduration,MPPolymer,MPSize,MPMorphology,EnvironmentallyRelevant,C_mean,C_sd,C_rep,C_n,S1_mean,S1_sd,S1_rep,S1_n,S2_mean,S2_sd,S2_rep,S2_n,S1_S2_mean,S1_S2_sd,S1_S2_rep,S1_S2_n,ManualExtraction,FirstAuthor,Year,Species,Family,Lifestage,Ecology,AdditiveNullModel,Sd_p,n_p,j,s,HedgesdAdditive,VdAdditive,pooled.sample,T.value,S.error,Conf95,lower,upper,int.type
1,1,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Survival rate,Survival rate,Percent,Ecological,Climate change X Ecological,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,80,5.0568,3,60,83.528,8.4672,3,60,85.7624,9.408,3,60,80,9.2904,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,89.2904,8.94997,60,0.993631,9.121773,-1.012,0.037601,180,1.973305,0.193909,0.382641,-1.39464,-0.62936,Antagonistic
1,2,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Body length,Body length/body length growth,mm,Ecological,Climate change X Ecological,Y,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,27.2385,2.3199,3,60,28.4595,2.7676,3,60,28.7037,2.4013,3,60,27.8897,2.2385,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,29.9247,2.590931,60,0.993631,2.421137,-0.83516,0.03624,180,1.973305,0.190367,0.375652,-1.21081,-0.45951,Antagonistic
1,3,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Post exposure predatory performance,Post exposure predatory performance,Percent,Ecological,Climate change X Ecological,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,69.4882,10.6386,3,60,26.4974,6.4974,3,60,56.7076,14.994,3,60,56.8504,11.1384,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,13.7168,11.555,60,0.993631,11.34861,-3.77657,0.09276,180,1.973305,0.304566,0.601002,-4.37757,-3.17557,Antagonistic
1,4,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Climate change X Metabolic,Y,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,2.0594,0.187,3,60,1.1232,0.2398,3,60,2.2112,0.176,3,60,1.2508,0.0484,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,1.275,0.210333,60,0.993631,0.152615,0.157559,0.033437,180,1.973305,0.182857,0.360833,-0.20327,0.518392,Additive
1,5,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Trypsin activity,Trypsin activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,2732.323,196.9695,3,60,1045.454,217.1715,3,60,2500,257.5755,3,60,1272.727,308.0805,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,813.131,238.2316,60,0.993631,275.3796,-1.65832,0.044792,180,1.973305,0.211641,0.417632,-2.07596,-1.24069,Antagonistic
1,6,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Lipase activity,Lipase activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,36.1952,11.3344,3,60,24.4352,10.208,3,60,22.112,9.4336,3,60,19.2224,7.744,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,10.352,9.82843,60,0.993631,8.847813,-0.99617,0.037468,180,1.973305,0.193567,0.381966,-1.37813,-0.6142,Antagonistic
1,7,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Amylase activity,Amylase activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,0.07047,0.00539,3,60,0.04803,0.01029,3,60,0.03833,0.00637,3,60,0.03431,0.00931,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,0.01589,0.008557,60,0.993631,0.008942,-2.0469,0.050791,180,1.973305,0.225368,0.44472,-2.49162,-1.60218,Antagonistic
1,8,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,555,25,3,60,453,15,3,60,269,11,3,60,200,10,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,167,13.15295,60,0.993631,11.68332,-2.80655,0.066153,180,1.973305,0.257202,0.507539,-3.31409,-2.29901,Antagonistic
1,9,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Electron transport system activity,Electron transport system activity,J/mg/sample,Biochemical,Climate change X Biochemical,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,3.5336,1.4342,3,60,6.284,1.8744,3,60,5.4768,1.1076,3,60,7.0498,2.059,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,8.2272,1.539505,60,0.993631,1.817905,-0.64354,0.035059,180,1.973305,0.18724,0.369482,-1.01303,-0.27406,Antagonistic
1,10,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,93.1098,3.333,3,60,134.8874,2.8886,3,60,135.1096,5.3328,3,60,124.2218,2.6664,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,176.8872,4.288518,60,0.993631,3.570789,-14.655,0.928205,180,1.973305,0.963434,1.90115,-16.5562,-12.7539,Antagonistic
1,11,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Citrate synthase activity,Citrate synthase activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,5.5544,0.1856,3,60,6,0.9976,3,60,3.508,0.812,3,60,5.1948,0.174,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,3.9536,0.909547,60,0.993631,0.654809,-1.88344,0.048114,180,1.973305,0.219349,0.432842,-2.31628,-1.4506,Antagonistic
1,12,"Microplastics have a more profound impact than elevated temperatures on the predatory performance, digestion and energy metabolism of an Amazonian cichlid",Climate change,Climate change,Warming,2,,Cytochrome c oxidase activity,Cytochrome c oxidase activity,U/mgProtein,Metabolic,Climate change X Metabolic,N,2,Micro g/L,Celsius,N,30,PE,88,Spheres,N,24.872,4.872,3,60,38.988,9.408,3,60,22.352,4.116,3,60,30,7.728,3,60,Y,Wen,2018,Symphysodon aequifasciatus,Cichlidae,Juvenile,Benthopelagic,36.468,7.261264,60,0.993631,7.498265,-0.85711,0.036394,180,1.973305,0.190773,0.376453,-1.23356,-0.48065,Antagonistic
2,13,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glucose level,Glucose level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,71.6306,2.4822,3,30,107.4466,10.9926,3,30,107.4466,8.5104,3,30,110.2834,2.4822,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,143.2626,9.830162,30,0.987013,7.169149,-4.54041,0.238461,90,1.986979,0.488325,0.970291,-5.5107,-3.57012,Antagonistic
2,14,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glucose level,Glucose level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,71.6306,2.4822,3,30,107.4466,10.9926,3,30,123.049,2.8368,3,30,103.9006,1.4184,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,158.865,8.027599,30,0.987013,5.764295,-9.41148,0.8048,90,1.986979,0.897107,1.782532,-11.194,-7.62895,Antagonistic
2,15,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glucose level,Glucose level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,71.6306,2.4822,3,30,105.319,16.3116,3,30,107.4466,8.5104,3,30,141.4882,27.3042,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,141.135,13.00952,30,0.987013,21.38653,0.016301,0.066669,90,1.986979,0.258203,0.513044,-0.49674,0.529345,Additive
2,16,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glucose level,Glucose level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,71.6306,2.4822,3,30,105.319,16.3116,3,30,123.049,2.8368,3,30,128.7226,10.9926,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,156.7374,11.70717,30,0.987013,11.35551,-2.43503,0.116078,90,1.986979,0.340702,0.676968,-3.112,-1.75806,Antagonistic
2,17,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Creatine level,Creatine level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0.2578,0.0204,3,30,0.4323,0.2091,3,30,0.3479,0.0221,3,30,0.5751,0.1071,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.5224,0.14868,30,0.987013,0.129569,0.401452,0.06801,90,1.986979,0.260787,0.518178,-0.11673,0.91963,Additive
2,18,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Creatine level,Creatine level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0.2578,0.0204,3,30,0.4323,0.2091,3,30,0.417,0.0595,3,30,0.6187,0.1904,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.5915,0.153726,30,0.987013,0.173037,0.15515,0.066867,90,1.986979,0.258587,0.513807,-0.35866,0.668957,Additive
2,19,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Creatine level,Creatine level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0.2578,0.0204,3,30,0.519,0.1666,3,30,0.3479,0.0221,3,30,0.5802,0.1173,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.6091,0.118836,30,0.987013,0.11807,-0.24159,0.067153,90,1.986979,0.259139,0.514904,-0.75649,0.273314,Additive
2,20,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Creatine level,Creatine level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0.2578,0.0204,3,30,0.519,0.1666,3,30,0.417,0.0595,3,30,0.6289,0.1054,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.6782,0.125092,30,0.987013,0.115666,-0.42069,0.068142,90,1.986979,0.261039,0.51868,-0.93937,0.097986,Additive
2,21,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Triglyceride level,Triglyceride level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,122.5675,9.2925,3,30,158.85,11.0625,3,30,141.595,10.1775,3,30,199.56,18.585,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,177.8775,10.62921,30,0.987013,15.13906,1.413622,0.083319,90,1.986979,0.288651,0.573543,0.840078,1.987165,Synergistic
2,22,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Triglyceride level,Triglyceride level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,122.5675,9.2925,3,30,158.85,11.0625,3,30,150,13.7175,3,30,188.055,12.39,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,186.2825,12.46091,30,0.987013,12.42551,0.140798,0.066832,90,1.986979,0.258519,0.513671,-0.37287,0.654468,Additive
2,23,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Triglyceride level,Triglyceride level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,122.5675,9.2925,3,30,185.8425,30.975,3,30,141.595,10.1775,3,30,205.7525,12.8325,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,204.87,23.05463,30,0.987013,18.65729,0.046686,0.066685,90,1.986979,0.258234,0.513106,-0.46642,0.559792,Additive
2,24,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Triglyceride level,Triglyceride level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,122.5675,9.2925,3,30,185.8425,30.975,3,30,150,13.7175,3,30,217.2575,20.7975,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,213.275,23.95434,30,0.987013,22.43152,0.175235,0.066923,90,1.986979,0.258694,0.514019,-0.33878,0.689254,Additive
2,25,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Cholesterol level,Cholesterol level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,346.2165,36.9732,3,30,242.015,57.1404,3,30,300,63.0225,3,30,155.4598,18.4866,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,195.7985,60.15339,30,0.987013,44.49823,0.894751,0.073338,90,1.986979,0.27081,0.538094,0.356657,1.432845,Synergistic
2,26,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Cholesterol level,Cholesterol level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,346.2165,36.9732,3,30,242.015,57.1404,3,30,300,14.2851,3,30,128.5702,15.9657,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,195.7985,41.64787,30,0.987013,31.53925,2.103893,0.103553,90,1.986979,0.321797,0.639403,1.46449,2.743296,Synergistic
2,27,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Cholesterol level,Cholesterol level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,346.2165,36.9732,3,30,135.2926,16.806,3,30,300,63.0225,3,30,205.8821,14.2851,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,89.0761,46.12091,30,0.987013,34.1409,-3.37686,0.161693,90,1.986979,0.402111,0.798986,-4.17585,-2.57787,Antagonistic
2,28,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Cholesterol level,Cholesterol level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,346.2165,36.9732,3,30,135.2926,16.806,3,30,300,14.2851,3,30,149.5777,15.9657,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,89.0761,15.59657,30,0.987013,15.78221,-3.78374,0.185973,90,1.986979,0.431246,0.856876,-4.64062,-2.92687,Antagonistic
2,29,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,High-density lipoprotein level,High-density lipoprotein levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,100,2.577,3,30,77.3162,2.3193,3,30,79.6355,5.154,3,30,55.6694,7.4733,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,56.9517,3.996428,30,0.987013,5.992564,0.211203,0.067038,90,1.986979,0.258918,0.514464,-0.30326,0.725667,Additive
2,30,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,High-density lipoprotein level,High-density lipoprotein levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,100,2.577,3,30,77.3162,2.3193,3,30,85.3049,7.731,3,30,61.0811,1.5462,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,62.6211,5.707342,30,0.987013,4.181178,0.363534,0.067768,90,1.986979,0.260323,0.517256,-0.15372,0.88079,Additive
2,31,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,High-density lipoprotein level,High-density lipoprotein levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,100,2.577,3,30,64.6889,12.1119,3,30,79.6355,5.154,3,30,80.924,1.5462,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,44.3244,9.307573,30,0.987013,6.671643,-5.4146,0.310982,90,1.986979,0.557658,1.108055,-6.52265,-4.30655,Antagonistic
2,32,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,High-density lipoprotein level,High-density lipoprotein levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,100,2.577,3,30,64.6889,12.1119,3,30,85.3049,7.731,3,30,77.3162,8.2464,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,49.9938,10.16038,30,0.987013,9.253009,-2.91446,0.137451,90,1.986979,0.370744,0.73666,-3.65112,-2.1778,Antagonistic
2,33,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Low-density lipoprotein level,Low-density lipoprotein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,61.2501,11.3898,3,30,52.9177,2.3613,3,30,40,2.9169,3,30,26.6672,4.5837,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,31.6676,2.653681,30,0.987013,3.745152,1.317826,0.081139,90,1.986979,0.284849,0.565989,0.751838,1.883815,Synergistic
2,34,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Low-density lipoprotein level,Low-density lipoprotein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,61.2501,11.3898,3,30,52.9177,2.3613,3,30,54.7234,5.6949,3,30,30.0008,2.0835,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,46.391,4.359336,30,0.987013,3.416488,4.735079,0.253508,90,1.986979,0.503496,1.000436,3.734643,5.735514,Synergistic
2,35,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Low-density lipoprotein level,Low-density lipoprotein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,61.2501,11.3898,3,30,31.5287,4.3059,3,30,40,2.9169,3,30,47.2228,8.334,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.2786,3.677573,30,0.987013,6.441277,-5.66105,0.333729,90,1.986979,0.577693,1.147864,-6.80892,-4.51319,Antagonistic
2,36,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Low-density lipoprotein level,Low-density lipoprotein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,61.2501,11.3898,3,30,31.5287,4.3059,3,30,54.7234,5.6949,3,30,44.3059,3.7503,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,25.002,5.048399,30,0.987013,4.44697,-4.28454,0.219644,90,1.986979,0.468662,0.931221,-5.21576,-3.35331,Antagonistic
2,37,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total protein level,Total protein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,3.9546,0.1204,3,30,3.2322,0.0602,3,30,3.129,0.1118,3,30,2.602,0.1548,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.4066,0.089787,30,0.987013,0.12654,-1.52412,0.086025,90,1.986979,0.293299,0.58278,-2.1069,-0.94134,Antagonistic
2,38,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total protein level,Total protein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,3.9546,0.1204,3,30,3.2322,0.0602,3,30,3,0.1032,3,30,2.6278,0.0688,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.2776,0.084482,30,0.987013,0.077041,-4.48661,0.234414,90,1.986979,0.484163,0.962021,-5.44863,-3.52459,Antagonistic
2,39,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total protein level,Total protein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,3.9546,0.1204,3,30,2.7482,0.2322,3,30,3.129,0.1118,3,30,2.7052,0.1204,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.9226,0.182231,30,0.987013,0.154441,-5.00149,0.275124,90,1.986979,0.524523,1.042216,-6.04371,-3.95927,Antagonistic
2,40,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total protein level,Total protein level,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,3.9546,0.1204,3,30,2.7482,0.2322,3,30,3,0.1032,3,30,2.8342,0.1032,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.7936,0.179676,30,0.987013,0.146516,-7.01007,0.476175,90,1.986979,0.690055,1.371124,-8.38119,-5.63894,Antagonistic
2,41,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Albumin level,Albumin,mg/dL,Biochemical,Pathogens X Biochemical,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.8333,0.066,3,30,1.7541,0.0561,3,30,1.7475,0.0561,3,30,1.4686,0.0726,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.6683,0.0561,30,0.987013,0.064877,3.038171,0.143587,90,1.986979,0.378929,0.752924,2.285247,3.791096,Synergistic
2,42,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Albumin level,Albumin,mg/dL,Biochemical,Pathogens X Biochemical,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.8333,0.066,3,30,1.7541,0.0561,3,30,1.8465,0.0561,3,30,1.5297,0.0693,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.7673,0.0561,30,0.987013,0.063046,3.719709,0.181969,90,1.986979,0.426578,0.847601,2.872108,4.56731,Synergistic
2,43,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Albumin level,Albumin,mg/dL,Biochemical,Pathogens X Biochemical,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.8333,0.066,3,30,1.5891,0.0693,3,30,1.7475,0.0561,3,30,1.5924,0.0825,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.5033,0.063046,30,0.987013,0.07342,-1.1978,0.078623,90,1.986979,0.280397,0.557144,-1.75494,-0.64066,Antagonistic
2,44,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Albumin level,Albumin,mg/dL,Biochemical,Pathogens X Biochemical,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.8333,0.066,3,30,1.5891,0.0693,3,30,1.8465,0.0561,3,30,1.7211,0.0429,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.6023,0.063046,30,0.987013,0.053922,-2.17455,0.106072,90,1.986979,0.325687,0.647134,-2.82169,-1.52742,Antagonistic
2,45,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Globulin level,Globulin levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,2.1134,0.147,3,30,1.4578,0.0966,3,30,1.3654,0.1134,3,30,1.1218,0.0588,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.7098,0.105335,30,0.987013,0.085302,-4.76715,0.256048,90,1.986979,0.506012,1.005434,-5.77258,-3.76172,Antagonistic
2,46,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Globulin level,Globulin levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,2.1134,0.147,3,30,1.4578,0.0966,3,30,1.126,0.0924,3,30,1.1008,0.084,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.4704,0.094523,30,0.987013,0.089417,-6.95858,0.470182,90,1.986979,0.685698,1.362468,-8.32105,-5.59612,Antagonistic
2,47,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Globulin level,Globulin levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,2.1134,0.147,3,30,1.357,0.1764,3,30,1.3654,0.1134,3,30,1.1134,0.0798,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.609,0.148284,30,0.987013,0.119072,-4.18108,0.212345,90,1.986979,0.460809,0.915618,-5.09669,-3.26546,Antagonistic
2,48,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Globulin level,Globulin levels,mg/dL,Biochemical,Pathogens X Biochemical,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,2.1134,0.147,3,30,1.357,0.1764,3,30,1.126,0.0924,3,30,1.1134,0.0966,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.3696,0.14081,30,0.987013,0.120745,-6.08007,0.374727,90,1.986979,0.612149,1.216328,-7.29639,-4.86374,Antagonistic
2,49,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Immunoglobulin level,Immunoglobulin level,mg/dL,Immunological,Pathogens X Immunological,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.7924,0.034,3,30,1.3502,0.0748,3,30,1.3332,0.051,3,30,0.6768,0.119,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.891,0.064016,30,0.987013,0.095548,2.21268,0.107466,90,1.986979,0.32782,0.651372,1.561308,2.864052,Synergistic
2,50,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Immunoglobulin level,Immunoglobulin level,mg/dL,Immunological,Pathogens X Immunological,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.7924,0.034,3,30,1.3502,0.0748,3,30,1.3196,0.051,3,30,0.5748,0.2142,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.8774,0.064016,30,0.987013,0.158082,1.88934,0.096413,90,1.986979,0.310505,0.616967,1.272373,2.506307,Synergistic
2,51,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Immunoglobulin level,Immunoglobulin level,mg/dL,Immunological,Pathogens X Immunological,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.7924,0.034,3,30,1.0918,0.1326,3,30,1.3332,0.051,3,30,0.738,0.1326,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.6326,0.100458,30,0.987013,0.117632,-0.88438,0.073184,90,1.986979,0.270526,0.53753,-1.42191,-0.34685,Antagonistic
2,52,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Immunoglobulin level,Immunoglobulin level,mg/dL,Immunological,Pathogens X Immunological,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.7924,0.034,3,30,1.0918,0.1326,3,30,1.3196,0.051,3,30,0.6496,0.2278,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.619,0.100458,30,0.987013,0.176046,-0.17156,0.066912,90,1.986979,0.258673,0.513979,-0.68554,0.342418,Additive
2,57,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutamic-pyruvic transaminase activity,Glutamic-pyruvic transaminase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,6.903,1.3275,3,30,15.0445,5.2215,3,30,11.947,1.3275,3,30,16.549,3.2745,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,20.0885,3.809614,30,0.987013,3.552148,-0.9835,0.074727,90,1.986979,0.273363,0.543166,-1.52666,-0.44033,Antagonistic
2,58,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutamic-pyruvic transaminase activity,Glutamic-pyruvic transaminase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,6.903,1.3275,3,30,15.0445,5.2215,3,30,9.204,1.1505,3,30,17.965,5.841,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,17.3455,3.780722,30,0.987013,4.919916,0.124282,0.066795,90,1.986979,0.258448,0.513531,-0.38925,0.637812,Additive
2,59,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutamic-pyruvic transaminase activity,Glutamic-pyruvic transaminase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,6.903,1.3275,3,30,24.8675,7.434,3,30,11.947,1.3275,3,30,18.85,5.487,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,29.9115,5.339785,30,0.987013,5.413893,-2.01663,0.100557,90,1.986979,0.317107,0.630085,-2.64672,-1.38655,Antagonistic
2,60,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutamic-pyruvic transaminase activity,Glutamic-pyruvic transaminase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,6.903,1.3275,3,30,24.8675,7.434,3,30,9.204,1.1505,3,30,17.08,5.5755,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,27.1685,5.319211,30,0.987013,5.448862,-1.82744,0.094496,90,1.986979,0.307402,0.610802,-2.43824,-1.21664,Antagonistic
2,61,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,153.9726,19.4678,3,30,375.2102,143.3538,3,30,307.9578,46.0148,3,30,408.849,99.1088,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,529.1954,106.4605,30,0.987013,102.8504,-1.15492,0.077782,90,1.986979,0.278894,0.554157,-1.70907,-0.60076,Antagonistic
2,62,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,153.9726,19.4678,3,30,375.2102,143.3538,3,30,376.98,38.9356,3,30,332.735,24.7772,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,598.2176,105.0388,30,0.987013,76.31204,-3.43373,0.164921,90,1.986979,0.406104,0.806921,-4.24065,-2.62681,Antagonistic
2,63,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,153.9726,19.4678,3,30,352.2028,127.4256,3,30,307.9578,46.0148,3,30,384.0592,30.0866,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,506.188,95.79834,30,0.987013,71.00185,-1.69774,0.090686,90,1.986979,0.301141,0.598361,-2.2961,-1.09938,Antagonistic
2,64,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,153.9726,19.4678,3,30,352.2028,127.4256,3,30,376.98,38.9356,3,30,555.7424,21.2376,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,575.2102,94.21588,30,0.987013,68.29227,-0.28136,0.067326,90,1.986979,0.259473,0.515568,-0.79693,0.234204,Additive
2,65,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1394.557,170.0675,3,30,2428.57,122.4486,3,30,2306.122,306.1215,3,30,2442.176,74.8297,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3340.135,233.1352,30,0.987013,173.1351,-5.11911,0.285044,90,1.986979,0.533895,1.060839,-6.17995,-4.05827,Antagonistic
2,66,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1394.557,170.0675,3,30,2428.57,122.4486,3,30,2068.027,122.4486,3,30,2564.624,292.5161,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3102.041,122.4486,30,0.987013,224.2313,-2.36558,0.1133,90,1.986979,0.3366,0.668818,-3.0344,-1.69676,Antagonistic
2,67,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1394.557,170.0675,3,30,2217.686,95.2378,3,30,2306.122,306.1215,3,30,2551.019,102.0405,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3129.251,226.6943,30,0.987013,175.7876,-3.24666,0.154507,90,1.986979,0.393074,0.781029,-4.02769,-2.46563,Antagonistic
2,68,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,mg/dL,Metabolic,Pathogens X Metabolic,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1394.557,170.0675,3,30,2217.686,95.2378,3,30,2068.027,122.4486,3,30,2476.189,115.6459,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2891.157,109.6902,30,0.987013,112.7074,-3.634,0.176716,90,1.986979,0.420376,0.835279,-4.46928,-2.79872,Antagonistic
2,69,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,?-glutamyltransferase activity,?-glutamyltransferase activity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,9.329,1.1322,3,30,6.4985,1.4652,3,30,6.4985,0.9324,3,30,4.0626,0.8325,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3.668,1.228043,30,0.987013,1.049082,-0.37125,0.067815,90,1.986979,0.260414,0.517436,-0.88869,0.146183,Additive
2,70,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,?-glutamyltransferase activity,?-glutamyltransferase activity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,9.329,1.1322,3,30,6.4985,1.4652,3,30,5.0283,0.8658,3,30,3.7629,0.7326,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.1978,1.203416,30,0.987013,0.996221,-1.55063,0.086704,90,1.986979,0.294455,0.585076,-2.13571,-0.96556,Antagonistic
2,71,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,?-glutamyltransferase activity,?-glutamyltransferase activity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,9.329,1.1322,3,30,4.7952,0.7992,3,30,6.4985,0.9324,3,30,4.1958,0.9324,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.9647,0.868358,30,0.987013,0.900948,-2.44423,0.116452,90,1.986979,0.341251,0.678058,-3.12229,-1.76617,Antagonistic
2,72,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,?-glutamyltransferase activity,?-glutamyltransferase activity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,9.329,1.1322,3,30,4.7952,0.7992,3,30,5.0283,0.8658,3,30,3.9294,0.9657,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.4945,0.833166,30,0.987013,0.901871,-3.75918,0.184428,90,1.986979,0.429451,0.85331,-4.61249,-2.90587,Antagonistic
2,73,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Catalase actviity,Catalase activity/expression,mg/dL,Metabolic,Pathogens X Metabolic,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,15,1.6992,3,30,16.0384,2.832,3,30,14.72,1.3216,3,30,10.944,1.6048,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,15.7584,2.209847,30,0.987013,1.931167,-2.46062,0.117122,90,1.986979,0.342231,0.680006,-3.14063,-1.78062,Antagonistic
2,74,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Catalase actviity,Catalase activity/expression,mg/dL,Metabolic,Pathogens X Metabolic,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,15,1.6992,3,30,16.0384,2.832,3,30,15.3304,1.416,3,30,8.9648,0.944,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,16.3688,2.238893,30,0.987013,1.718106,-4.25343,0.217431,90,1.986979,0.466295,0.926517,-5.17995,-3.32691,Antagonistic
2,75,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Catalase actviity,Catalase activity/expression,mg/dL,Metabolic,Pathogens X Metabolic,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,15,1.6992,3,30,13.7288,1.5104,3,30,14.72,1.3216,3,30,9.5784,1.0384,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,13.4488,1.419143,30,0.987013,1.243431,3.072253,0.145323,90,1.986979,0.381212,0.757461,2.314792,3.829714,Synergistic
2,76,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Catalase actviity,Catalase activity/expression,mg/dL,Metabolic,Pathogens X Metabolic,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,15,1.6992,3,30,13.7288,1.5104,3,30,15.3304,1.416,3,30,6.5104,0.3304,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,14.0592,1.463961,30,0.987013,1.061213,7.020988,0.477452,90,1.986979,0.690979,1.372961,5.648027,8.393949,Synergistic
2,77,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,4.556,0.4031,3,30,3.6402,0.3058,3,30,4,0.7506,3,30,3.5846,0.4448,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3.0842,0.573112,30,0.987013,0.512983,-0.9628,0.074392,90,1.986979,0.272748,0.541945,-1.50475,-0.42086,Antagonistic
2,78,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,4.556,0.4031,3,30,3.6402,0.3058,3,30,3.7375,0.5838,3,30,2.7228,0.4865,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.8217,0.466013,30,0.987013,0.476367,0.204917,0.067017,90,1.986979,0.258876,0.51438,-0.30946,0.719297,Additive
2,79,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,4.556,0.4031,3,30,3.529,0.417,3,30,4,0.7506,3,30,2.9869,0.4031,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.973,0.607161,30,0.987013,0.515332,-0.02662,0.066673,90,1.986979,0.25821,0.513058,-0.53968,0.486436,Additive
2,80,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,4.556,0.4031,3,30,3.529,0.417,3,30,3.7375,0.5838,3,30,2.695,0.2502,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,2.7105,0.507302,30,0.987013,0.399972,0.038249,0.066679,90,1.986979,0.258222,0.513083,-0.47483,0.551332,Additive
2,81,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Superoxide dismutase activity,Superoxide dismutase activity/expression,mg/dL,Stress response,Pathogens X Stress response,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.3776,0.236,3,30,2.6372,0.1534,3,30,2.2596,0.1534,3,30,3.7316,0.3658,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3.5192,0.1534,30,0.987013,0.280483,0.747431,0.071322,90,1.986979,0.267062,0.530646,0.216785,1.278078,Synergistic
2,82,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Superoxide dismutase activity,Superoxide dismutase activity/expression,mg/dL,Stress response,Pathogens X Stress response,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.3776,0.236,3,30,2.6372,0.1534,3,30,2.9086,0.236,3,30,4.2596,0.3422,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,4.1682,0.199032,30,0.987013,0.279924,0.322277,0.067532,90,1.986979,0.25987,0.516355,-0.19408,0.838632,Additive
2,83,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Superoxide dismutase activity,Superoxide dismutase activity/expression,mg/dL,Stress response,Pathogens X Stress response,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.3776,0.236,3,30,3.472,0.5074,3,30,2.2596,0.1534,3,30,4.1446,0.1298,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,4.354,0.374824,30,0.987013,0.280483,-0.73687,0.071192,90,1.986979,0.266817,0.530161,-1.26703,-0.20671,Antagonistic
2,84,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Superoxide dismutase activity,Superoxide dismutase activity/expression,mg/dL,Stress response,Pathogens X Stress response,Y,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,1.3776,0.236,3,30,3.472,0.5074,3,30,2.9086,0.236,3,30,4.5782,0.1888,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,5.003,0.395696,30,0.987013,0.310017,-1.35245,0.081909,90,1.986979,0.286198,0.56867,-1.92112,-0.78378,Antagonistic
2,85,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Malondialdehyde levels,Malondialdehyde levels,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0,0,3,30,0.4582,0.1392,3,30,0.4292,0.0464,3,30,1.232,0.2668,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.8874,0.103754,30,0.987013,0.202419,1.680299,0.090195,90,1.986979,0.300325,0.596739,1.08356,2.277038,Synergistic
2,86,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Malondialdehyde levels,Malondialdehyde levels,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0,0,3,30,0.4582,0.1392,3,30,0.5,0.0464,3,30,1.4698,0.377,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.9582,0.103754,30,0.987013,0.27649,1.826306,0.094462,90,1.986979,0.307346,0.61069,1.215616,2.436996,Synergistic
2,87,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Malondialdehyde levels,Malondialdehyde levels,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0,0,3,30,0.5696,0.2088,3,30,0.4292,0.0464,3,30,1.2726,0.2436,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.9988,0.151245,30,0.987013,0.202751,1.332885,0.081472,90,1.986979,0.285432,0.567148,0.765737,1.900033,Synergistic
2,88,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Malondialdehyde levels,Malondialdehyde levels,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,0,0,3,30,0.5696,0.2088,3,30,0.5,0.0464,3,30,1.6508,0.4466,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.0696,0.151245,30,0.987013,0.333412,1.720551,0.091336,90,1.986979,0.302218,0.600501,1.12005,2.321052,Synergistic
2,89,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total antioxidant levels,Total antioxidant capacity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,58.1293,3.738,3,30,46.9153,3.1773,3,30,42.6166,4.2987,3,30,50.0926,4.2987,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,31.4026,3.779819,30,0.987013,4.047583,-4.5576,0.239765,90,1.986979,0.489658,0.972939,-5.53054,-3.58466,Antagonistic
2,90,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total antioxidant levels,Total antioxidant capacity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,58.1293,3.738,3,30,46.9153,3.1773,3,30,37.9424,1.4952,3,30,40,3.9249,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,26.7284,2.483028,30,0.987013,3.284073,-3.98872,0.199249,90,1.986979,0.446373,0.886934,-4.87565,-3.10178,Antagonistic
2,91,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total antioxidant levels,Total antioxidant capacity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,58.1293,3.738,3,30,47.2891,3.9249,3,30,42.6166,4.2987,3,30,42.0559,5.4201,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,31.7764,4.116046,30,0.987013,4.812448,-2.10828,0.103707,90,1.986979,0.322036,0.639878,-2.74816,-1.4684,Antagonistic
2,92,Effect of microplastics on Yersinia ruckeri infection in rainbow trout (Oncorhynchus mykiss),Pathogens,Bacterial infection,Yersinia ruckeri exposure,3,,Total antioxidant levels,Total antioxidant capacity,mg/dL,Stress response,Pathogens X Stress response,N,3,mg/kg,PercentLD50,N,30,HDPE,199,Undisclosed,N,58.1293,3.738,3,30,47.2891,3.9249,3,30,37.9424,1.4952,3,30,32.3354,1.1214,3,30,Y,Banihashemi,2022,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,27.1022,2.969887,30,0.987013,2.244746,-2.30103,0.11079,90,1.986979,0.332851,0.661367,-2.9624,-1.63967,Antagonistic
3,93,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Degree of gill tissue change,Degree of gill tissue change,NA,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,55.865,20.1114,8,8,256.979,185.4718,4,4,558.6566,96.0878,4,4,668.152,268.152,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,759.7706,147.7035,4,0.869565,216.4738,-0.36803,0.508465,12,2.200985,0.713068,1.569451,-1.93748,1.201423,Additive
3,94,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Degree of gill tissue change,Degree of gill tissue change,NA,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,55.865,20.1114,8,8,256.979,185.4718,4,4,489.384,210.0524,4,4,1101.671,250.2752,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,690.498,198.1436,4,0.869565,225.7195,1.584009,0.656818,12,2.200985,0.810443,1.783773,-0.19976,3.367782,Additive
3,95,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Degree of gill tissue change,Degree of gill tissue change,NA,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,55.865,20.1114,8,8,668.152,205.5832,4,4,558.6566,96.0878,4,4,766.4744,156.422,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1170.944,160.4639,4,0.869565,158.4558,-2.21962,0.807921,12,2.200985,0.898844,1.978342,-4.19797,-0.24128,Antagonistic
3,96,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Degree of gill tissue change,Degree of gill tissue change,NA,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,55.865,20.1114,8,8,668.152,205.5832,4,4,489.384,210.0524,4,4,1184.351,297.2018,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1101.671,207.8298,4,0.869565,256.4392,0.280362,0.504913,12,2.200985,0.710572,1.563959,-1.2836,1.844321,Additive
3,97,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Liver glycogen stores,Liver glycogen stores,Percent staining intensity,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,14.8128,5.4896,8,8,13.4968,5.0384,4,4,39.4752,8.9488,4,4,8.9488,7.6704,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,38.1592,7.261766,4,0.869565,7.468878,-3.40083,1.222851,12,2.200985,1.105826,2.433906,-5.83473,-0.96692,Antagonistic
3,98,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Liver glycogen stores,Liver glycogen stores,Percent staining intensity,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,14.8128,5.4896,8,8,13.4968,5.0384,4,4,7.7456,4.7752,4,4,7.9336,4.512,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,6.4296,4.908564,4,0.869565,4.714454,-0.27741,0.50481,12,2.200985,0.7105,1.563799,-1.84121,1.286391,Additive
3,99,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Liver glycogen stores,Liver glycogen stores,Percent staining intensity,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,14.8128,5.4896,8,8,9.212,3.6472,4,4,39.4752,8.9488,4,4,29.4752,3.948,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,33.8744,6.833121,4,0.869565,5.580244,-0.68552,0.529371,12,2.200985,0.727579,1.601391,-2.28691,0.915867,Additive
3,100,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Liver glycogen stores,Liver glycogen stores,Percent staining intensity,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,14.8128,5.4896,8,8,9.212,3.6472,4,4,7.7456,4.7752,4,4,34.0984,6.5424,4,4,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.1448,4.2488,4,0.869565,5.516126,-5.03718,2.085826,12,2.200985,1.444239,3.178748,-8.21593,-1.85843,Antagonistic
3,101,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Cholesterol levels,Cholesterol level,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,4.5104,0.3944,10,10,3.4408,0.4408,5,5,4.0348,0.2436,5,5,4.3364,0.2204,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.9652,0.356122,5,0.903226,0.296141,-4.18214,1.274515,15,2.144787,1.128944,2.421344,-6.60349,-1.7608,Antagonistic
3,102,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Cholesterol levels,Cholesterol level,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,4.5104,0.3944,10,10,3.4408,0.4408,5,5,3.696,0.3828,5,5,4.754,0.3712,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.6264,0.41282,5,0.903226,0.392562,-4.89529,1.598192,15,2.144787,1.264196,2.711431,-7.60672,-2.18386,Antagonistic
3,103,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Cholesterol levels,Cholesterol level,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,4.5104,0.3944,10,10,4.1972,0.3712,5,5,4.0348,0.2436,5,5,4.406,0.0348,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,3.7216,0.313951,5,0.903226,0.223356,-2.76763,0.782988,15,2.144787,0.884866,1.897849,-4.66548,-0.86978,Antagonistic
3,104,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Cholesterol levels,Cholesterol level,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,4.5104,0.3944,10,10,4.1972,0.3712,5,5,3.696,0.3828,5,5,4.1972,0.3132,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,3.3828,0.377045,5,0.903226,0.346595,-2.12232,0.625212,15,2.144787,0.790704,1.695891,-3.81821,-0.42643,Antagonistic
3,105,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,High-density lipoprotein levels,High-density lipoprotein levels,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,3.3999,0.2232,10,10,2.4836,0.3999,5,5,3.1488,0.4743,5,5,3.3348,0.6324,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.2325,0.43868,5,0.903226,0.544229,-1.82943,0.56734,15,2.144787,0.75322,1.615495,-3.44492,-0.21393,Antagonistic
3,106,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,High-density lipoprotein levels,High-density lipoprotein levels,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,3.3999,0.2232,10,10,2.4836,0.3999,5,5,2.9721,0.2976,5,5,3.6789,0.0279,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.0558,0.352481,5,0.903226,0.250021,-5.8636,2.119092,15,2.144787,1.45571,3.122188,-8.98579,-2.74142,Antagonistic
3,107,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,High-density lipoprotein levels,High-density lipoprotein levels,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,3.3999,0.2232,10,10,2.6882,0.3999,5,5,3.1488,0.4743,5,5,3.2697,0.2604,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.4371,0.43868,5,0.903226,0.360727,-2.08475,0.617309,15,2.144787,0.78569,1.685138,-3.76989,-0.39961,Antagonistic
3,108,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,High-density lipoprotein levels,High-density lipoprotein levels,nmol/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,3.3999,0.2232,10,10,2.6882,0.3999,5,5,2.9721,0.2976,5,5,3,0.4371,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,2.2604,0.352481,5,0.903226,0.397051,-1.68247,0.541535,15,2.144787,0.735891,1.578328,-3.2608,-0.10414,Antagonistic
3,109,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Albumin levels,Albumin,g/L,Biochemical,Organic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.2792,0.7678,10,10,11.6524,1.0819,5,5,13.8148,0.8725,5,5,13.5007,0.1745,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,13.188,0.982793,5,0.903226,0.705809,0.400163,0.408007,15,2.144787,0.638754,1.369991,-0.96983,1.770154,Additive
3,110,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Albumin levels,Albumin,g/L,Biochemical,Organic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.2792,0.7678,10,10,11.6524,1.0819,5,5,11.2336,1.4309,5,5,13.9893,1.2564,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,10.6068,1.26846,5,0.903226,1.262444,-2.42004,0.692829,15,2.144787,0.832363,1.785242,-4.20528,-0.63479,Antagonistic
3,111,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Albumin levels,Albumin,g/L,Biochemical,Organic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.2792,0.7678,10,10,13.2564,0.6282,5,5,13.8148,0.8725,5,5,13.8497,0.6282,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,14.792,0.760227,5,0.903226,0.697345,-1.2205,0.474481,15,2.144787,0.688826,1.477384,-2.69788,0.256885,Additive
3,112,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Albumin levels,Albumin,g/L,Biochemical,Organic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.2792,0.7678,10,10,13.2564,0.6282,5,5,11.2336,1.4309,5,5,13.8846,1.2564,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,12.2108,1.105014,5,0.903226,1.183131,-1.27781,0.48164,15,2.144787,0.694003,1.488489,-2.7663,0.210676,Additive
3,113,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Globulin levels,Globulin levels,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.1125,0.675,10,10,9.6375,1.875,5,5,13.125,0.8625,5,5,10.35,0.225,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,10.65,1.459372,5,0.903226,1.044124,0.259517,0.403367,15,2.144787,0.635112,1.36218,-1.10266,1.621697,Additive
3,114,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Globulin levels,Globulin levels,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.1125,0.675,10,10,9.6375,1.875,5,5,11.4375,2.2125,5,5,12.825,0.3375,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,8.9625,2.050705,5,0.903226,1.469574,-2.37396,0.681784,15,2.144787,0.825702,1.770955,-4.14491,-0.603,Antagonistic
3,115,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Globulin levels,Globulin levels,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.1125,0.675,10,10,11.8875,1.0875,5,5,13.125,0.8625,5,5,14.5875,0.9375,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,12.9,0.981469,5,0.903226,0.959736,1.588138,0.526109,15,2.144787,0.725334,1.555686,0.032452,3.143824,Synergistic
3,116,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Globulin levels,Globulin levels,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,12.1125,0.675,10,10,11.8875,1.0875,5,5,11.4375,2.2125,5,5,12.675,1.5,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,11.2125,1.743246,5,0.903226,1.626177,-0.81231,0.432993,15,2.144787,0.658022,1.411317,-2.22363,0.599002,Additive
3,117,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Total protein levels,Total protein level,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,24.704,1.3965,10,10,21.3965,1.911,5,5,26.911,2.1315,5,5,23.7485,0.2205,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,23.6035,2.024255,5,0.903226,1.439831,-0.09096,0.400414,15,2.144787,0.632782,1.357183,-1.44814,1.266223,Additive
3,118,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Total protein levels,Total protein level,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,24.704,1.3965,10,10,21.3965,1.911,5,5,22.7195,1.764,5,5,26.8375,2.058,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,19.412,1.838969,5,0.903226,1.95156,-3.43669,0.990541,15,2.144787,0.995259,2.134619,-5.57131,-1.30207,Antagonistic
3,119,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Total protein levels,Total protein level,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,24.704,1.3965,10,10,25.145,2.793,5,5,26.911,2.1315,5,5,28.4545,0.5145,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,27.352,2.484365,5,0.903226,1.793987,0.55508,0.415406,15,2.144787,0.64452,1.382357,-0.82728,1.937437,Additive
3,120,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Total protein levels,Total protein level,g/L,Biochemical,Organic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,24.704,1.3965,10,10,25.145,2.793,5,5,22.7195,1.764,5,5,28.4545,0.5145,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,23.1605,2.335867,5,0.903226,1.691299,-2.82722,0.799659,15,2.144787,0.894237,1.917947,-4.74517,-0.90928,Antagonistic
3,125,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain gonadotropin-releasing hormone transcription levels,Gonadotropin-releasing hormone transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.8525,0.235,10,10,0.5625,0.1925,5,5,0.7,0.21,5,5,0.5225,0.1,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,0.41,0.20144,5,0.903226,0.159025,-0.63897,0.420414,15,2.144787,0.648394,1.390666,-2.02964,0.751693,Additive
3,126,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain gonadotropin-releasing hormone transcription levels,Gonadotropin-releasing hormone transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.8525,0.235,10,10,0.5625,0.1925,5,5,0.7575,0.275,5,5,0.575,0.4125,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,0.4675,0.237362,5,0.903226,0.336524,-0.28853,0.404162,15,2.144787,0.635738,1.363522,-1.65205,1.074993,Additive
3,127,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain gonadotropin-releasing hormone transcription levels,Gonadotropin-releasing hormone transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.8525,0.235,10,10,0.825,0.255,5,5,0.7,0.21,5,5,0.1775,0.04,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,0.6725,0.233586,5,0.903226,0.167575,2.668046,0.755923,15,2.144787,0.869439,1.86476,0.803286,4.532806,Synergistic
3,128,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain gonadotropin-releasing hormone transcription levels,Gonadotropin-releasing hormone transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.8525,0.235,10,10,0.825,0.255,5,5,0.7575,0.275,5,5,0.53,0.21,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,0.73,0.265189,5,0.903226,0.239191,0.755233,0.428519,15,2.144787,0.654613,1.404006,-0.64877,2.159239,Additive
3,129,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain 11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.558,0.063,10,10,0.972,0.249,5,5,0.996,0.315,5,5,0.864,0.054,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1.41,0.283924,5,0.903226,0.204364,-2.41316,0.691166,15,2.144787,0.831364,1.783098,-4.19625,-0.63006,Antagonistic
3,130,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain 11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.558,0.063,10,10,0.972,0.249,5,5,1.188,0.12,5,5,0.714,0.168,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1.602,0.195449,5,0.903226,0.182242,-4.40109,1.368479,15,2.144787,1.16982,2.509015,-6.9101,-1.89207,Antagonistic
3,131,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain 11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.558,0.063,10,10,1.251,0.105,5,5,0.996,0.315,5,5,0.852,0.057,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1.689,0.234787,5,0.903226,0.170842,-4.42514,1.379093,15,2.144787,1.174348,2.518726,-6.94387,-1.90641,Antagonistic
3,132,Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus),Organic pollutants,Polycylic aromatic hydrocarbons,Phenanthrene,3,,Brain 11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,11 ?-hydroxysteroid dehydrogenase type 2 transcription levels,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,LDPE,59,Fragments,N,0.558,0.063,10,10,1.251,0.105,5,5,1.188,0.12,5,5,0.945,0.174,5,5,Y,Karami,2016,Clarias gariepinus,Clariidae,Juvenile,Benthopelagic,1.881,0.11275,5,0.903226,0.146609,-5.76648,2.062616,15,2.144787,1.436181,3.080302,-8.84679,-2.68618,Antagonistic
4,133,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Survival rate,Survival rate,Percent,Ecological,Organic pollutants X Ecological,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,96.25,2.125,3,600,95.5,1.25,3,600,94.625,0.875,3,600,95.5,0.75,3,600,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,93.875,1.078917,600,0.999374,0.929129,-1.74785,0.004606,1800,1.961284,0.067869,0.133111,-1.88097,-1.61474,Antagonistic
4,134,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Body weight,Body mass/body mass growth,g,Ecological,Organic pollutants X Ecological,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,3.78E-01,0.003,3,45,3.24E-01,0.008,3,45,3.22E-01,0.005,3,45,3.20E-01,0.012,3,45,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.68E-01,0.006671,45,9.91E-01,0.009708,-5.31049,0.201118,135,1.977826,0.448462,0.88698,-6.19747,-4.42351,Antagonistic
4,135,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Body length,Body length/body length growth,mm,Ecological,Organic pollutants X Ecological,Y,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,4.68,0.09,3,45,4.76,0.07,3,45,4.61,0.05,3,45,4.6,0.09,3,45,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,4.69,0.060828,45,0.991453,0.076811,-1.16169,0.051942,135,1.977826,0.227907,0.450761,-1.61245,-0.71092,Antagonistic
4,136,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Body mass index,Body mass index,g/cm2,Ecological,Organic pollutants X Ecological,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,0.00165,9.00E-05,3,45,0.00142,7.00E-05,3,45,0.00148,4.00E-05,3,45,0.0015,5.00E-05,3,45,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.00125,5.70E-05,45,0.991453,5.36E-05,-4.62267,0.163162,135,1.977826,0.403933,0.798909,-5.42158,-3.82376,Antagonistic
4,137,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,4.436,0.159,3,135,4.623,0.375,3,135,3.685,0.094,3,135,5.3177,0.4683,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.872,2.73E-01,135,0.997199,0.383429,-3.75989,0.040994,405,1.965853,0.20247,0.398026,-4.15792,-3.36186,Antagonistic
4,138,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,65.018,1.536,3,135,61.464,1.249,3,135,59.255,4.418,3,135,54.069,2.305,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,55.701,3.246438,135,0.997199,2.81535,0.578056,0.015434,405,1.965853,0.124232,0.244222,0.333834,0.822278,Synergistic
4,139,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,5.186,1.06,3,135,3.845,0.469,3,135,4.623,1.126,3,135,3.282,0.15,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.282,0.862507,135,0.997199,0.619039,0,0.014815,405,1.965853,0.121716,0.239276,-0.23928,0.239276,Additive
4,140,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,118.081,9.779,3,135,111.808,21.033,3,135,90.465,6.029,3,135,89.114,16.606,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,84.192,15.47152,135,0.997199,16.04879,-0.30583,0.014988,405,1.965853,0.122426,0.240671,-0.5465,-0.06516,Antagonistic
4,141,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,NO production,NO production,Micromol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,12.976,1.39,3,135,15.791,1.146,3,135,11.502,1.805,3,135,17.725,1.78,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,14.317,1.511843,135,0.997199,1.651374,2.057956,0.022658,405,1.965853,0.150525,0.29591,1.762046,2.353865,Synergistic
4,142,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,inos expression,inos expression,Fold-change,Metabolic,Organic pollutants X Metabolic,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,0.979,0.185,3,135,1.626,0.356,3,135,1.196,0.052,3,135,1.562,0.42,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.843,0.254401,135,0.997199,0.347218,-0.80702,0.016021,405,1.965853,0.126574,0.248825,-1.05585,-0.5582,Antagonistic
4,143,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Lysozyme activity,Lysozyme activity,U/mgProtein,Immunological,Organic pollutants X Immunological,Y,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,142.611,6.748,3,135,114.714,12.505,3,135,118.786,15.75,3,135,80.632,9.25,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,90.889,14.22036,135,0.997199,11.99544,0.85268,0.016161,405,1.965853,0.127127,0.249913,0.602767,1.102592,Synergistic
4,144,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,Immunoglobulin M level,Immunoglobulin M level,Micro g/mgProtein,Immunological,Organic pollutants X Immunological,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,97.701,8.248,3,135,114.637,5.062,3,135,88.63,6.379,3,135,122.43,11.25,3,135,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,105.566,5.758276,135,0.997199,8.936449,1.881817,0.021373,405,1.965853,0.146194,0.287396,1.594421,2.169213,Synergistic
4,145,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,NOS protein,NOS protein,Fold-change,Biochemical,Organic pollutants X Biochemical,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,0.995,0.144,3,45,1.387,0.094,3,45,1.4,0.173,3,45,2.066,0.281,3,45,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.792,0.139221,45,0.991453,0.221747,1.225081,0.052782,135,1.977826,0.229744,0.454394,0.770687,1.679475,Synergistic
4,146,Polystyrene microplastics decrease F–53B bioaccumulation but induce inflammatory stress in larval zebrafish,Organic pollutants,Organic pollutants (other),F–53B,2,,NF-?B expression,NF-?B expression,Fold-change,Immunological,Organic pollutants X Immunological,N,2,ng/ml,ng/ml,N,7,PS,5,Spheres,Y,0.988,0.092,3,45,2.264,0.23,3,45,2.632,0.264,3,45,3.172,0.207,3,45,Y,Yang,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.908,0.247584,45,0.991453,0.228196,-3.19773,0.101253,135,1.977826,0.318202,0.629348,-3.82708,-2.56838,Antagonistic
5,157,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,96 hpf,Mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,6,mg/L,mg/L,Y,4,PS,9,Undisclosed,Y,8.145,0,3,240,40.145,1.745,3,240,45.09,2.037,3,240,34.909,1.745,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,77.09,1.896628,240,0.99843,1.822392,-23.1096,0.56464,720,1.963269,0.751426,1.47525,-24.5849,-21.6344,Antagonistic
5,158,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,96 hpf,Mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,6,mg/L,mg/L,Y,4,PS,9,Undisclosed,Y,8.145,0,3,240,50.036,2.327,3,240,45.09,2.037,3,240,34.909,1.745,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,86.981,2.186813,240,0.99843,1.978279,-26.2805,0.727778,720,1.963269,0.853099,1.674863,-27.9554,-24.6057,Antagonistic
5,159,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,96 hpf,Mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,6,mg/L,mg/L,Y,4,PS,9,Undisclosed,Y,8.145,0,3,240,54.981,2.619,3,240,45.09,2.037,3,240,40.145,1.745,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,91.926,2.346117,240,0.99843,2.067521,-25.0056,0.659669,720,1.963269,0.8122,1.594567,-26.6002,-23.4111,Antagonistic
5,160,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,96 hpf,Mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,6,mg/L,mg/L,Y,4,PS,9,Undisclosed,Y,8.145,0,3,240,57.018,2.909,3,240,45.09,2.037,3,240,45.09,2.037,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,93.963,2.51114,240,0.99843,2.286394,-21.342,0.482794,720,1.963269,0.694834,1.364145,-22.7062,-19.9779,Antagonistic
5,161,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,96 hpf,Mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,6,mg/L,mg/L,Y,4,PS,9,Undisclosed,Y,8.145,0,3,240,60.218,2.909,3,240,45.09,2.037,3,240,50.036,2.036,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,97.163,2.51114,240,0.99843,2.285948,-20.5836,0.449671,720,1.963269,0.670575,1.316519,-21.9001,-19.2671,Antagonistic
5,162,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,48 hpe,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,163.702,2.043,3,240,155.532,4.085,3,240,149.064,3.234,3,240,161.319,5.617,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,140.894,3.684154,240,0.99843,4.74993,-4.29331,0.027534,720,1.963269,0.165933,0.325772,-4.61908,-3.96754,Antagonistic
5,163,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,48 hpe,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,163.702,2.043,3,240,153.319,1.532,3,240,149.064,3.234,3,240,156.043,2.723,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,138.681,2.530393,240,0.99843,2.628461,-6.59502,0.05364,720,1.963269,0.231603,0.454698,-7.04971,-6.14032,Antagonistic
5,164,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,48 hpe,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,163.702,2.043,3,240,149.064,3.234,3,240,149.064,3.234,3,240,149.745,5.446,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,134.426,3.234,240,0.99843,4.478709,-3.41504,0.020482,720,1.963269,0.143114,0.280972,-3.69601,-3.13406,Antagonistic
5,165,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,48 hpe,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,163.702,2.043,3,240,149.574,3.575,3,240,149.064,3.234,3,240,146.681,2.042,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,134.936,3.408767,240,0.99843,2.809756,-4.17352,0.026477,720,1.963269,0.162719,0.31946,-4.49298,-3.85406,Antagonistic
5,166,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,48 hpe,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,163.702,2.043,3,240,141.064,2.893,3,240,149.064,3.234,3,240,139.191,4.766,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,126.426,3.068241,240,0.99843,4.008046,-3.17984,0.018866,720,1.963269,0.137354,0.269662,-3.44951,-2.91018,Antagonistic
5,167,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,3.603,0.035,3,240,3.522,0.035,3,240,3.582,0.034,3,240,3.607,0.034,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,3.501,0.034504,240,0.99843,0.034253,-3.08979,0.018278,720,1.963269,0.135196,0.265426,-3.35521,-2.82436,Antagonistic
5,168,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,3.603,0.035,3,240,3.529,0.034,3,240,3.582,0.034,3,240,3.557,0.031,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,3.508,0.034,240,0.99843,0.032535,-1.50372,0.010689,720,1.963269,0.103386,0.202975,-1.7067,-1.30075,Antagonistic
5,169,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,3.603,0.035,3,240,3.504,0.034,3,240,3.582,0.034,3,240,3.354,0.035,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,3.483,0.034,240,0.99843,0.034504,3.732869,0.022848,720,1.963269,0.151156,0.296761,3.436108,4.029629,Synergistic
5,170,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,3.603,0.035,3,240,3.532,0.031,3,240,3.582,0.034,3,240,3.146,0.031,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,3.511,0.032535,240,0.99843,0.031777,11.46842,0.145338,720,1.963269,0.381232,0.748462,10.71996,12.21688,Synergistic
5,171,Combined toxicity of microplastics and cadmium on the zebrafish embryos (Danio rerio),Inorganic pollutants,Metal contaminants,Cadmium,2,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,6,mg/L,mg/L,N,4,PS,9,Undisclosed,Y,3.603,0.035,3,240,3.522,0.035,3,240,3.582,0.034,3,240,3.13,0.031,3,240,Y,Zhang,2020,Danio rerio,Danionidae,Embryos,Benthopelagic,3.501,0.034504,240,0.99843,0.032799,11.29369,0.141195,720,1.963269,0.37576,0.737717,10.55597,12.03141,Synergistic
6,172,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae height,Primary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,7204.68,280.7,2,10,5286.55,467.84,1,5,6128.65,187.14,1,5,3836.26,233.92,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,4210.52,356.2974,5,0.903226,301.3855,1.121624,0.462902,15,2.144787,0.680369,1.459247,-0.33762,2.580871,Additive
6,173,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae height,Primary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,7204.68,280.7,2,10,4912.28,93.57,1,5,6128.65,187.14,1,5,3929.82,93.57,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,3836.25,147.9472,5,0.903226,123.7815,-0.68277,0.423309,15,2.144787,0.650622,1.395446,-2.07822,0.712671,Additive
6,174,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae height,Primary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,7204.68,280.7,2,10,5286.55,467.84,1,5,5005.85,46.78,1,5,3929.82,187.14,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,3087.72,332.4625,5,0.903226,269.7709,-2.81945,0.797466,15,2.144787,0.893009,1.915315,-4.73477,-0.90414,Antagonistic
6,175,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae height,Primary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,7204.68,280.7,2,10,4912.28,93.57,1,5,5005.85,46.78,1,5,2011.7,93.56,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,2713.45,73.972,5,0.903226,84.33662,7.515581,3.224198,15,2.144787,1.795605,3.85119,3.664391,11.36677,Synergistic
6,176,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae thickness,Primary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,326.667,10,2,10,326.667,20,1,5,296.667,20,1,5,340,43.333,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,296.667,20,5,0.903226,33.74721,-1.15978,0.467255,15,2.144787,0.683561,1.466091,-2.62588,0.306307,Additive
6,177,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae thickness,Primary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,326.667,10,2,10,370,36.667,1,5,296.667,20,1,5,270,33.333,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,340,29.53362,5,0.903226,31.49066,-2.00776,0.601556,15,2.144787,0.7756,1.663497,-3.67126,-0.34427,Antagonistic
6,178,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae thickness,Primary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,326.667,10,2,10,326.667,20,1,5,243.333,23.334,1,5,460,60,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,243.333,21.73103,5,0.903226,45.12337,-4.33698,1.34047,15,2.144787,1.157787,2.483206,-6.82019,-1.85378,Antagonistic
6,179,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Primary lamellae thickness,Primary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,326.667,10,2,10,370,36.667,1,5,243.333,23.334,1,5,340,13.333,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,286.666,30.73227,5,0.903226,23.68798,-2.03363,0.606783,15,2.144787,0.778963,1.670709,-3.70434,-0.36292,Antagonistic
6,180,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae height,Secondary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,164.541,10.204,2,10,121.173,21.684,1,5,142.857,8.929,1,5,128.827,17.857,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,99.489,16.58196,5,0.903226,17.23128,-1.53783,0.518247,15,2.144787,0.719893,1.544018,-3.08185,0.006184,Additive
6,181,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae height,Secondary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,164.541,10.204,2,10,117.347,25.51,1,5,142.857,8.929,1,5,89.285,6.378,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,95.663,19.11135,5,0.903226,14.24645,0.404366,0.408176,15,2.144787,0.638886,1.370275,-0.96591,1.77464,Additive
6,182,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae height,Secondary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,164.541,10.204,2,10,121.173,21.684,1,5,113.52,16.582,1,5,198.98,17.857,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,70.152,19.30231,5,0.903226,18.59371,-6.25807,2.358174,15,2.144787,1.535635,3.293609,-9.55168,-2.96446,Antagonistic
6,183,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae height,Secondary lamellae height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,164.541,10.204,2,10,117.347,25.51,1,5,113.52,16.582,1,5,147.959,15.306,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,66.326,21.51421,5,0.903226,18.66996,-3.94929,1.179843,15,2.144787,1.086206,2.32968,-6.27897,-1.61961,Antagonistic
6,184,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae thickness,Secondary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,32.58,2.903,2,10,17.741,7.42,1,5,25.161,3.226,1,5,29.354,7.42,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,10.322,5.721166,5,0.903226,6.62526,-2.59464,0.736609,15,2.144787,0.858259,1.840783,-4.43543,-0.75386,Antagonistic
6,185,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae thickness,Secondary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,32.58,2.903,2,10,28.064,2.258,1,5,25.161,3.226,1,5,20.645,2.258,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,20.645,2.784389,5,0.903226,2.534895,1.27E-15,0.4,15,2.144787,0.632456,1.356482,-1.35648,1.356482,Additive
6,186,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae thickness,Secondary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,32.58,2.903,2,10,17.741,7.42,1,5,22.903,2.903,1,5,43.548,7.419,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,8.064,5.633995,5,0.903226,6.58724,-4.86548,1.583643,15,2.144787,1.258429,2.699062,-7.56454,-2.16642,Antagonistic
6,187,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Secondary lamellae thickness,Secondary lamellae thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,32.58,2.903,2,10,28.064,2.258,1,5,22.903,2.903,1,5,26.129,2.58,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,18.387,2.600574,5,0.903226,2.590308,-2.69959,0.76439,15,2.144787,0.874294,1.875174,-4.57477,-0.82442,Antagonistic
6,188,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb height of folds,Intestinal bulb height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,1024.72,94.38,2,10,573.034,128.09,1,5,869.663,256.177,1,5,451.685,40.45,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,417.977,202.5262,5,0.903226,146.036,-0.20848,0.402173,15,2.144787,0.634171,1.360162,-1.56864,1.15168,Additive
6,189,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb height of folds,Intestinal bulb height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,1024.72,94.38,2,10,492.135,40.454,1,5,869.663,256.177,1,5,404.494,13.484,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,337.078,183.3892,5,0.903226,130.0258,-0.46831,0.410966,15,2.144787,0.641066,1.37495,-1.84326,0.906644,Additive
6,190,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb height of folds,Intestinal bulb height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,1024.72,94.38,2,10,573.034,128.09,1,5,795.506,107.865,1,5,532.584,101.124,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,343.82,118.4101,5,0.903226,110.1068,-1.54846,0.519887,15,2.144787,0.721032,1.54646,-3.09492,-0.002,Antagonistic
6,191,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb height of folds,Intestinal bulb height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,1024.72,94.38,2,10,492.135,40.454,1,5,795.506,107.865,1,5,337.079,40.449,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,262.921,81.45976,5,0.903226,64.31102,-1.04152,0.454239,15,2.144787,0.673972,1.445527,-2.48705,0.404003,Additive
6,192,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica muscularis,Intestinal bulb thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,47.777,11.111,2,10,37.777,4.445,1,5,57.777,11.111,1,5,153.333,28.889,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,47.777,8.462043,5,0.903226,21.28592,4.47906,1.403099,15,2.144787,1.184525,2.540553,1.938507,7.019613,Synergistic
6,193,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica muscularis,Intestinal bulb thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,47.777,11.111,2,10,42.222,6.667,1,5,57.777,11.111,1,5,123.333,25.556,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,52.222,9.162511,5,0.903226,19.19714,3.345773,0.95971,15,2.144787,0.979648,2.101136,1.244637,5.446909,Synergistic
6,194,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica muscularis,Intestinal bulb thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,47.777,11.111,2,10,37.777,4.445,1,5,164.444,16.667,1,5,34.444,10,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,154.444,12.19727,5,0.903226,11.15288,-9.71831,5.122273,15,2.144787,2.263244,4.854176,-14.5725,-4.86413,Antagonistic
6,195,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica muscularis,Intestinal bulb thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,47.777,11.111,2,10,42.222,6.667,1,5,164.444,16.667,1,5,26.666,2.222,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,158.889,12.69326,5,0.903226,9.111975,-13.1066,8.989179,15,2.144787,2.998196,6.430491,-19.5371,-6.67613,Antagonistic
6,196,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica sub mucosa,Intestinal bulb thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,30.983,3.825,2,10,29.836,6.12,1,5,39.398,4.973,1,5,36.338,13.006,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,38.251,5.576071,5,0.903226,10.00621,-0.17268,0.401491,15,2.144787,0.633633,1.359008,-1.53169,1.186328,Additive
6,197,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica sub mucosa,Intestinal bulb thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,30.983,3.825,2,10,29.836,5.737,1,5,39.398,4.973,1,5,21.42,2.678,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,38.251,5.368608,5,0.903226,4.242265,-3.58351,1.042077,15,2.144787,1.020822,2.189444,-5.77295,-1.39406,Antagonistic
6,198,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica sub mucosa,Intestinal bulb thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,30.983,3.825,2,10,29.836,6.12,1,5,56.994,7.268,1,5,23.715,3.443,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,55.847,6.718565,5,0.903226,5.338228,-5.43672,1.877896,15,2.144787,1.370364,2.939137,-8.37586,-2.49758,Antagonistic
6,199,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Intestinal bulb thickness of tunica sub mucosa,Intestinal bulb thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,30.983,3.825,2,10,29.836,5.737,1,5,56.994,7.268,1,5,24.098,3.825,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,55.847,6.547404,5,0.903226,5.361862,-5.34824,1.830183,15,2.144787,1.352843,2.901559,-8.2498,-2.44668,Antagonistic
6,200,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut height of folds,Midgut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,532.164,28.655,2,10,319.298,32.749,1,5,511.696,65.497,1,5,253.801,73.684,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,298.83,51.78008,5,0.903226,63.68088,0.638675,0.420395,15,2.144787,0.648379,1.390635,-0.75196,2.029309,Additive
6,201,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut height of folds,Midgut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,532.164,28.655,2,10,290.648,69.586,1,5,511.696,65.497,1,5,147.368,57.31,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,270.18,67.57244,5,0.903226,6.27E+01,1.770534,0.55674,15,2.144787,0.74615,1.600332,0.170202,3.370866,Synergistic
6,202,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut height of folds,Midgut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,532.164,28.655,2,10,319.298,32.749,1,5,462.573,32.749,1,5,302.924,40.936,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,249.707,32.749,5,0.903226,37.06921,-1.29668,0.484069,15,2.144787,0.695751,1.492237,-2.78892,0.195555,Additive
6,203,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut height of folds,Midgut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,532.164,28.655,2,10,290.648,69.586,1,5,462.573,32.749,1,5,184.211,16.374,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,221.057,54.38156,5,0.903226,40.15882,0.828716,0.434339,15,2.144787,0.659044,1.413508,-0.58479,2.242224,Additive
6,204,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica muscularis,Midgut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.329,5.689,2,10,25.449,5.089,1,5,19.76,0.898,1,5,15.868,2.096,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,9.88,3.654061,5,0.903226,2.978706,-1.81573,0.564843,15,2.144787,0.75156,1.611937,-3.42766,-0.20379,Antagonistic
6,205,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica muscularis,Midgut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.329,5.689,2,10,23.053,3.893,1,5,19.76,0.898,1,5,20.958,2.395,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,7.484,2.825053,5,0.903226,2.618869,-4.64707,1.479762,15,2.144787,1.216455,2.609036,-7.2561,-2.03803,Antagonistic
6,206,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica muscularis,Midgut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.329,5.689,2,10,25.449,5.089,1,5,30.538,5.09,1,5,39.221,5.689,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,20.658,5.0895,5,0.903226,5.39758,-3.10631,0.88246,15,2.144787,0.939393,2.014798,-5.12111,-1.09152,Antagonistic
6,207,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica muscularis,Midgut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.329,5.689,2,10,23.053,3.893,1,5,30.538,5.09,1,5,27.844,1.796,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,18.262,4.5312,5,0.903226,3.446548,-2.51112,0.715287,15,2.144787,0.845747,1.813946,-4.32507,-0.69718,Antagonistic
6,208,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica sub mucosa,Midgut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,22.5,4.23,2,10,20.384,0.962,1,5,21.153,2.693,1,5,11.923,0.961,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,19.037,2.02209,5,0.903226,1.583093,4.058857,1.223716,15,2.144787,1.106217,2.372599,1.686258,6.431456,Synergistic
6,209,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica sub mucosa,Midgut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,22.5,4.23,2,10,20.961,1.154,1,5,21.153,2.693,1,5,25.192,1.154,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,19.614,2.07171,5.00E+00,0.903226,1.676857,-3.00455,0.851365,15,2.144787,0.922694,1.978982,-4.98353,-1.02556,Antagonistic
6,210,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica sub mucosa,Midgut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,22.5,4.23,2,10,20.384,0.962,1,5,26.346,4.23,1,5,21.153,1.923,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,24.23,3.067437,5,0.903226,2.55999,-1.08564,0.458931,15,2.144787,0.677444,1.452973,-2.53861,0.367334,Additive
6,211,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Midgut thickness of tunica sub mucosa,Midgut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,22.5,4.23,2,10,20.961,1.154,1,5,26.346,4.23,1,5,23.269,1.154,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,24.807,3.100372,5,0.903226,2.339233,-0.59385,0.417633,15,2.144787,0.646245,1.386058,-1.97991,0.792205,Additive
6,212,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut height of folds,Posterior gut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,327.907,16.279,2,10,118.605,41.86,1,5,151.163,67.442,1,5,100,2.326,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-58.139,56.1279,5,0.903226,39.72249,-3.59583,1.046499,15,2.144787,1.022985,2.194085,-5.78991,-1.40174,Antagonistic
6,213,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut height of folds,Posterior gut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,327.907,16.279,2,10,113.953,48.838,1,5,151.163,67.442,1,5,100,9.302,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-62.791,58.87943,5,0.903226,42.15041,-3.48839,1.008443,15,2.144787,1.004213,2.153822,-5.64221,-1.33457,Antagonistic
6,214,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut height of folds,Posterior gut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,327.907,16.279,2,10,118.605,41.86,1,5,139.535,55.814,1,5,153.488,39.535,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-69.767,49.33286,5,0.903226,44.70317,-4.51086,1.417392,15,2.144787,1.190543,2.55346,-7.06432,-1.9574,Antagonistic
6,215,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut height of folds,Posterior gut height of folds,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,327.907,16.279,2,10,113.953,48.838,1,5,139.535,55.814,1,5,100,18.605,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-74.419,52.44212,5,0.903226,39.34668,-4.00389,1.201556,15,2.144787,1.096155,2.351019,-6.35491,-1.65287,Antagonistic
6,220,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica muscularis,Posterior gut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,89.655,24.828,2,10,15.862,2.069,1,5,22.758,3.448,1,5,29.655,4.138,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-51.035,2.843366,5,0.903226,3.550196,-20.5288,21.4716,15,2.144787,4.633746,9.938397,-30.4672,-10.5904,Antagonistic
6,221,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica muscularis,Posterior gut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,89.655,24.828,2,10,21.379,8.276,1,5,22.758,3.448,1,5,24.827,4.138,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-45.518,6.339593,5,0.903226,5.353199,-11.8691,7.443724,15,2.144787,2.728319,5.851662,-17.7207,-6.01739,Antagonistic
6,222,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica muscularis,Posterior gut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,89.655,24.828,2,10,15.862,2.069,1,5,26.206,3.449,1,5,28.275,4.828,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-47.587,2.843973,5,0.903226,3.962182,-17.2936,15.35349,15,2.144787,3.918353,8.404031,-25.6977,-8.8896,Antagonistic
6,223,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica muscularis,Posterior gut thickness of tunica muscularis,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,89.655,24.828,2,10,21.379,8.276,1,5,26.206,3.449,1,5,26.206,4.138,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-42.07,6.339865,5,0.903226,5.35336,-11.5196,7.035076,15,2.144787,2.652372,5.688771,-17.2084,-5.83084,Antagonistic
6,224,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica sub mucosa,Posterior gut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.542,5.12,2,10,10.542,2.108,1,5,22.289,3.313,1,5,25.903,7.229,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-2.711,2.776656,5,0.903226,5.475777,-4.71986,1.513854,15,2.144787,1.230388,2.63892,-7.35878,-2.08094,Antagonistic
6,225,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica sub mucosa,Posterior gut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.542,5.12,2,10,11.747,1.204,1,5,22.289,3.313,1,5,21.084,1.205,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-1.506,2.492547,5,0.903226,1.957654,-10.4226,5.831544,15,2.144787,2.414859,5.179358,-15.602,-5.24326,Antagonistic
6,226,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica sub mucosa,Posterior gut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.542,5.12,2,10,10.542,2.108,1,5,28.915,4.819,1,5,39.156,3.916,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,3.915,3.719303,5,0.903226,3.818918,-8.33497,3.873589,15,2.144787,1.968144,4.221248,-12.5562,-4.11373,Antagonistic
6,227,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Posterior gut thickness of tunica sub mucosa,Posterior gut thickness of tunica sub mucosa,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,35.542,5.12,2,10,11.747,1.204,1,5,28.915,4.819,1,5,23.795,1.205,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,5.12,3.512291,5,0.903226,2.625663,-6.42418,2.463507,15,2.144787,1.569556,3.366363,-9.79055,-3.05782,Antagonistic
6,228,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin number of goblet cells,Skin number of goblet cells,Number,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,6.518,1.314,2,10,4.037,0.827,1,5,6.275,0.973,1,5,3.94,0.097,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,3.794,0.902956,5,0.903226,0.64216,-0.20536,0.402109,15,2.144787,0.63412,1.360053,-1.56541,1.154697,Additive
6,229,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin number of goblet cells,Skin number of goblet cells,Number,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,6.518,1.314,2,10,4.524,1.313,1,5,6.275,0.973,1,5,5.254,1.264,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,4.281,1.155573,5,0.903226,1.211001,-0.72571,0.426333,15,2.144787,0.652942,1.400421,-2.12613,0.674708,Additive
6,230,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin number of goblet cells,Skin number of goblet cells,Number,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,6.518,1.314,2,10,4.037,0.827,1,5,5.01,0.827,1,5,3.016,0.827,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,2.529,0.827,5,0.903226,0.827,-0.53189,0.414145,15,2.144787,0.643541,1.380258,-1.91215,0.848371,Additive
6,231,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin number of goblet cells,Skin number of goblet cells,Number,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,6.518,1.314,2,10,4.524,1.313,1,5,5.01,0.827,1,5,1.994,0.876,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,3.016,1.097246,5,0.903226,0.992805,0.929786,0.443225,15,2.144787,0.665752,1.427895,-0.49811,2.357681,Additive
6,232,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin epithelium height,Skin epithelium height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,246.959,45.161,2,10,156.359,11.298,1,5,81.996,11.298,1,5,70.437,9.409,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-8.604,11.298,5,0.903226,10.39649,-6.86692,2.757729,15,2.144787,1.660641,3.561721,-10.4286,-3.3052,Antagonistic
6,233,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin epithelium height,Skin epithelium height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,246.959,45.161,2,10,103.802,15.054,1,5,81.996,11.298,1,5,83.748,20.699,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-61.161,13.30916,5,0.903226,17.4009,-7.52177,3.228851,15,2.144787,1.7969,3.853968,-11.3757,-3.6678,Antagonistic
6,234,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin epithelium height,Skin epithelium height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,246.959,45.161,2,10,156.359,11.298,1,5,105.207,13.18,1,5,104.931,13.172,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,14.607,12.27512,5,0.903226,12.73146,-6.40798,2.453111,15,2.144787,1.566241,3.359253,-9.76723,-3.04873,Antagonistic
6,235,Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos,Organic pollutants,Pesticides,Chlorpyrifos,3,,Skin epithelium height,Skin epithelium height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,4,PS,466.7,Pellets,Y,246.959,45.161,2,10,103.802,15.054,1,5,105.207,13.18,1,5,97.542,11.291,1,5,Y,Karbalaei,2021,Oncorhynchus mykis,Salmonidae,Juvenile,Benthopelagic,-37.95,14.14806,5,0.903226,12.7995,-9.5613,4.970925,15,2.144787,2.229557,4.781924,-14.3432,-4.77938,Antagonistic
7,236,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Glucose level,Glucose level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.384,0.026,4,6,0.341,0.026,4,6,0.315,0.021,4,6,0.338,0.02,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.272,0.023633,6,0.923077,0.021892,-2.78292,0.656027,18,2.109816,0.809955,1.708855,-4.49178,-1.07406,Antagonistic
7,237,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Pyruvate level,Pyruvate level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.0165,0.002,4,6,0.0114,0.0012,4,6,0.0149,0.002,4,6,0.013,0.0017,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.0098,0.001649,6,0.923077,0.001675,-1.76369,0.462941,18,2.109816,0.680398,1.435514,-3.1992,-0.32817,Antagonistic
7,238,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Triglyceride level,Triglyceride level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.145,0.019,4,6,0.102,0.011,4,6,0.11,0.018,4,6,0.103,0.015,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.067,0.014916,6,0.923077,0.014958,-2.22156,0.538973,18,2.109816,0.734148,1.548916,-3.77048,-0.67265,Antagonistic
7,239,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Total cholesterol level,Cholesterol level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,Y,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.06,0.005,4,6,0.048,0.0014,4,6,0.05,0.004,4,6,0.0521,0.0027,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.038,0.002997,6,0.923077,0.002852,-4.56329,1.200985,18,2.109816,1.095894,2.312135,-6.87543,-2.25116,Antagonistic
7,240,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Low-density lipoprotein cholesterol level,Low-density lipoprotein cholesterol level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.00998,2.00E-05,4,6,0.00728,0.00099,4,6,0.01,0.001,4,6,0.0087,0.00107,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.0073,0.000995,6,0.923077,0.001033,-1.2508,0.398521,18,2.109816,0.631285,1.331895,-2.58269,0.081097,Additive
7,241,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,NEFA level,NEFA level,nEQ/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,9.51E-02,0.0099,4,6,0.098,0.007,4,6,0.137,0.011,4,6,0.12,0.017,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.1399,0.00922,6,0.923077,0.013675,-1.34329,0.408518,18,2.109816,0.639154,1.348497,-2.69179,0.005206,Additive
7,242,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Gk expression,Gk expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.981,0.335,4,6,0.964,0.126,4,6,1.802,0.126,4,6,2.85,0.22,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.785,0.126,6,0.923077,0.179271,5.483755,1.586316,18,2.109816,1.25949,2.657292,2.826463,8.141047,Synergistic
7,243,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,HK1 expression,HK1 expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.968,0.122,4,6,1.534,0.352,4,6,1.257,0.252,4,6,4.679,0.604,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.823,0.306111,6,0.923077,0.478811,5.505946,1.596477,18,2.109816,1.263518,2.665789,2.840157,8.171735,Synergistic
7,244,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,PK expression,PK expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.99,0.126,4,6,0.902,0.12,4,6,0.817,0.126,4,6,1.044,0.094,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.729,0.123037,6,0.923077,0.109485,-2.65579,0.627217,18,2.109816,0.79197,1.670911,-4.3267,-0.98488,Antagonistic
7,245,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,PepKC expression,PepKC expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.998,0.183,4,6,0.562,0.11,4,6,0.349,0.101,4,6,0.438,0.126,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,-0.087,0.105596,6,0.923077,0.116247,-4.16886,1.057475,18,2.109816,1.028336,2.169599,-6.33846,-1.99926,Antagonistic
7,246,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,ACO expression,ACO expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.981,0.209,4,6,1.341,0.252,4,6,1.526,0.335,4,6,2.557,0.269,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.886,0.296419,6,0.923077,0.283042,2.188314,0.532863,18,2.109816,0.729975,1.540112,0.648202,3.728426,Synergistic
7,247,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Ppar-? expression,Ppar-? expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.99,0.101,4,6,0.823,0.057,4,6,0.949,0.057,4,6,0.572,0.104,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.782,0.057,6,0.923077,0.08386,2.311545,0.555968,18,2.109816,0.745633,1.573148,0.738397,3.884693,Synergistic
7,248,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Cpt 1 expression,Cpt 1 expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.93,0.378,4,6,1.886,0.302,4,6,1.257,0.252,4,6,6.842,0.83,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.213,0.278126,6,0.923077,0.618973,6.903251,2.318953,18,2.109816,1.522811,3.21285,3.690401,10.1161,Synergistic
7,249,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Acc expression,Acc expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.993,0.116,4,6,0.806,0.115,4,6,0.578,0.093,4,6,0.306,0.109,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.391,0.10458,6,0.923077,0.106813,0.73457,0.355816,18,2.109816,0.596503,1.258512,-0.52394,1.993082,Additive
7,250,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Fas expression,Fas expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.997,0.054,4,6,0.731,0.053,4,6,0.793,0.069,4,6,0.448,0.085,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.527,0.061522,6,0.923077,0.074196,0.982848,0.373583,18,2.109816,0.611214,1.289549,-0.3067,2.272397,Additive
7,251,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Srebp1a expression,Srebp1a expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.997,0.179,4,6,0.762,0.163,4,6,0.888,0.147,4,6,0.621,0.053,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.653,0.155206,6,0.923077,0.11597,0.254708,0.336037,18,2.109816,0.579687,1.223032,-0.96832,1.47774,Additive
7,252,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Ppar-? expression,Ppar-? expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.997,0.126,4,6,0.809,0.085,4,6,0.925,0.079,4,6,0.643,0.072,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.737,0.082055,6,0.923077,0.077191,1.12408,0.385982,18,2.109816,0.621274,1.310774,-0.18669,2.434854,Additive
7,253,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Apo expression,Apo expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.989,0.136,4,6,2.447,0.396,4,6,1.072,0.178,4,6,3.697,0.365,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.53,0.307002,6,0.923077,0.33725,3.194162,0.758445,18,2.109816,0.870887,1.837411,1.35675,5.031573,Synergistic
7,254,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Fabp6 expression,Fabp6 expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.969,0.304,4,6,5.208,1.137,4,6,4.061,0.884,4,6,7.062,1.896,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,8.3,1.018387,6,0.923077,1.521829,-0.75092,0.356828,18,2.109816,0.597351,1.260301,-2.01122,0.509382,Additive
7,255,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,LDL-R expression,LDL-R expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.987,0.125,4,6,1.008,0.418,4,6,1.033,0.23,4,6,1.502,0.167,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.054,0.33736,6,0.923077,0.266178,1.553619,0.433905,18,2.109816,0.658715,1.389767,0.163852,2.943386,Synergistic
7,256,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,66.44,2.373,4,6,73.898,5.763,4,6,73.898,4.407,4,6,74.915,5.424,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,81.356,5.130001,6,0.923077,5.279047,-1.12625,0.386185,18,2.109816,0.621438,1.31112,-2.43737,0.184867,Additive
7,257,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,47.346,2.722,4,6,65.034,7.619,4,6,57.687,4.081,4,6,66.938,6.259,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,75.375,6.111617,6,0.923077,6.185747,-1.25902,0.399381,18,2.109816,0.631966,1.333331,-2.59235,0.074308,Additive
7,258,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Glutathione content,Glutathione level,nmol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,75.593,4.746,4,6,54.576,5.763,4,6,62.372,4.407,4,6,61.355,6.441,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,41.355,5.130001,6,0.923077,5.822516,-3.17071,0.752226,18,2.109816,0.86731,1.829864,-5.00058,-1.34085,Antagonistic
7,259,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Malondialdehyde content,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,2.806,0.814,4,6,2.054,1.017,4,6,3.986,0.936,4,6,2.501,0.59,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,3.234,0.97734,6,0.923077,0.807246,-0.83818,0.362606,18,2.109816,0.602168,1.270463,-2.10864,0.432285,Additive
7,260,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Mn-sod expression,Mn-SOD activity/expression,Relative mRNA level,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.996,0.174,4,6,0.486,0.102,4,6,1.104,0.066,4,6,0.786,0.204,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.594,0.085907,6,0.923077,0.156518,-1.13233,0.386757,18,2.109816,0.621898,1.31209,-2.44442,0.179758,Additive
7,262,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Cat expression,Catalase activity/expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,1,0.168,4,6,0.608,0.144,4,6,0.952,0.168,4,6,1.32,0.304,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.56,0.156461,6,0.923077,0.24176,-2.90179,0.684184,18,2.109816,0.827154,1.745142,-4.64694,-1.15665,Antagonistic
7,263,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Nrf2 expression,Nrf2 expression,Relative mRNA level,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.996,0.162,4,6,0.408,0.108,4,6,0.744,0.114,4,6,0.57,0.12,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.156,0.111041,6,0.923077,0.115607,-3.30563,0.788632,18,2.109816,0.888049,1.873621,-5.17925,-1.43201,Antagonistic
7,264,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,keap1 expression,Keap1 expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.996,0.186,4,6,1.026,0.288,4,6,0.468,0.096,4,6,0.852,0.156,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.498,0.214663,6,0.923077,0.187638,-1.74149,0.459699,18,2.109816,0.678011,1.430479,-3.17197,-0.31101,Antagonistic
7,265,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Gpx expression,Glutathione peroxidase activity/expression,Relative mRNA level,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.99,0.246,4,6,0.468,0.138,4,6,0.57,0.126,4,6,0.684,0.18,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.048,0.132136,6,0.923077,0.157892,-3.71821,0.909378,18,2.109816,0.953613,2.011948,-5.73016,-1.70626,Antagonistic
7,266,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,Bcl2 expression,Bcl2 expression,Relative mRNA level,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.99,0.144,4,6,0.498,0.132,4,6,0.732,0.114,4,6,0.822,0.102,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.24,0.123329,6,0.923077,0.113168,-4.7472,1.272328,18,2.109816,1.127975,2.37982,-7.12702,-2.36738,Antagonistic
7,267,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,IL-1? expression,IL-1B expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.97,0.179,4,6,1.7,0.642,4,6,0.728,0.214,4,6,2.135,0.429,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.458,0.478519,6,0.923077,0.454434,1.375167,0.412129,18,2.109816,0.641972,1.354443,0.020724,2.72961,Synergistic
7,268,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,IL-6 expression,IL-6 expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.955,0.319,4,6,1.486,0.266,4,6,1.327,0.265,4,6,3.663,0.85,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.858,0.2655,6,0.923077,0.629679,2.646038,0.625063,18,2.109816,0.790609,1.66804,0.977998,4.314078,Synergistic
7,269,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,IL-8 expression,IL-8 expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.982,0.292,4,6,1.805,0.478,4,6,1.22,0.319,4,6,2.256,0.292,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.043,0.406353,6,0.923077,0.353827,0.555683,0.346199,18,2.109816,0.588387,1.241388,-0.68571,1.797071,Additive
7,270,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,TNF ? expression,TNF level/expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.991,0.354,4,6,2.336,0.637,4,6,1.274,0.283,4,6,4.814,1.345,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.619,0.492878,6,0.923077,1.012905,2.000339,0.500057,18,2.109816,0.707147,1.491949,0.50839,3.492288,Synergistic
7,271,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,IFN expression,IFN expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,1.23,0.322,4,6,1.53,0.251,4,6,1.416,0.179,4,6,2.645,0.606,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.716,0.217993,6,0.923077,0.455388,1.883093,0.481085,18,2.109816,0.693603,1.463374,0.419719,3.346467,Synergistic
7,272,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,C3 expression,Complement C3 level/expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,Y,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,1.276,0.143,4,6,1.755,0.143,4,6,2.034,0.143,4,6,2.619,0.5,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.513,0.143,6,0.923077,0.367729,0.266082,0.336283,18,2.109816,0.579899,1.223481,-0.9574,1.489563,Additive
7,273,Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription,Organic pollutants,Pesticides,Imidacloprid,2,,IL-10 expression,IL-10 expression,Relative mRNA level,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,21,PS,5,Spheres,Y,0.955,0.425,4,6,1.964,0.69,4,6,1.274,0.265,4,6,3.557,0.956,4,6,Y,Luo,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.283,0.52265,6,0.923077,0.770421,1.526437,0.430417,18,2.109816,0.656062,1.384169,0.142268,2.910607,Synergistic
8,275,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,P4501A activity,P4501A activity,U/L,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,45.919,0,3,6,45.919,2.946,3,6,53.604,1.473,3,6,47.584,1.921,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,53.604,2.329017,6,0.923077,2.134779,-2.60304,0.61566,18,2.109816,0.78464,1.655446,-4.25849,-0.9476,Antagonistic
8,277,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,4.18,0.115,3,6,4.07,0.05,3,6,4.199,0.604,3,6,3.977,0.654,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,4.089,0.428553,6,0.923077,0.55289,0.18699,0.33479,18,2.109816,0.578611,1.220762,-1.03377,1.407751,Additive
8,279,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,40.65,1.084,3,6,37.533,0.136,3,6,33.468,0.813,3,6,40.921,0.813,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,30.351,0.582866,6,0.923077,0.707355,-13.7935,8.260901,18,2.109816,2.874178,6.063986,-19.8575,-7.72955,Antagonistic
8,281,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,N,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,3.353,0.407,3,6,2.323,0.149,3,6,3.441,0.881,3,6,3.441,0.678,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,2.411,0.631808,6,0.923077,0.655311,-1.45087,0.421042,18,2.109816,0.648878,1.369012,-2.81988,-0.08185,Antagonistic
8,283,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,1.214,0.119,3,6,1.496,0.213,3,6,1.252,0.15,3,6,1.31,0.165,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.534,0.184213,6,0.923077,0.174871,-1.18241,0.391587,18,2.109816,0.625769,1.320258,-2.50267,0.137846,Additive
8,285,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Lipid peroxide level,Lipid peroxide level,Micro mol/mgProtein,Biochemical,Organic pollutants X Biochemical,N,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,65.863,3.855,3,6,95.421,10.603,3,6,91.566,1.606,3,6,57.349,12.369,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,121.124,7.582969,6,0.923077,10.25899,-5.73831,1.705341,18,2.109816,1.305887,2.755181,-8.49349,-2.98313,Antagonistic
8,287,"Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota",Organic pollutants,Polycylic aromatic hydrocarbons,9-Nitroanthracene,2,7 d,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/gProtein,Metabolic,Organic pollutants X Metabolic,N,2,mg/L,Micro g/L,Y,21,PE,150,Undisclosed,N,9188.27,96.42,3,6,8954.08,55.1,3,6,9463.788,137.742,3,6,8361.73,96.43,3,6,Y,Zhang,2021,Danio rerio,Danionidae,Adult,Benthopelagic,9229.598,104.902,6,0.923077,100.7551,-7.95105,2.967467,18,2.109816,1.722634,3.63444,-11.5855,-4.31661,Antagonistic
9,288,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,0.49,0.182,1,12,1.165,0.395,1,12,1.025,0.106,1,12,2.597,0.578,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.7,0.289189,12,0.941176,0.349517,2.415437,0.611145,27,2.055529,0.781757,1.606925,0.808512,4.022363,Synergistic
9,289,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/gProtein,Metabolic,Organic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,26.984,4.525,1,12,32.509,3.396,1,12,28.389,2.944,1,12,44.78,10.868,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,33.914,3.178046,12,0.941176,5.168891,1.978534,0.547153,27,2.055529,0.739698,1.520471,0.458063,3.499005,Synergistic
9,290,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,Glutathione content,Glutathione level,Micro mol/ml,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,178.243,35.146,1,12,212.134,16.318,1,12,217.155,6.276,1,12,230.962,60.251,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,251.046,12.36255,12,0.941176,26.22612,-0.72075,0.433983,27,2.055529,0.658774,1.354129,-2.07488,0.633375,Additive
9,291,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,IL-1? expression,IL-1B expression,Relative,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,0.502,0.042,1,12,0.0418,0.0412,1,12,5.319,1.047,1,12,0.418,0.126,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4.8588,0.740914,12,0.941176,0.683331,-6.11647,1.663708,27,2.055529,1.289848,2.651321,-8.76779,-3.46515,Antagonistic
9,292,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,IL-10 expression,IL-10 expression,Relative,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,1.005,0.209,1,12,0.125,0.126,1,12,5.319,0.921,1,12,1.172,0.377,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4.439,0.657312,12,0.941176,0.622458,-4.93981,1.230057,27,2.055529,1.109079,2.279745,-7.21955,-2.66006,Antagonistic
9,293,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,TGF-? expression,TGF-? expression,Relative,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,1.093,0.235,1,12,0.286,0.026,1,12,3.411,0.417,1,12,1.015,0.182,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,2.604,0.295436,12,0.941176,0.280981,-5.32253,1.360976,27,2.055529,1.166609,2.397998,-7.72052,-2.92453,Antagonistic
9,294,Interactive Effects of Microplastics and Tetracycline on Bioaccumulation and Biochemical Status in Jian Carp (Cyprinus carpio var. Jian),Organic pollutants,Antibiotics,Tetracycline,2,,TLR-2 expression,TLR-2 expression,Relative,Immunological,Organic pollutants X Immunological,N,2,Micro g/L,Micro g/L,N,4,PS,5,Spheres,Y,1.015,0.235,1,12,1.171,0.469,1,12,8.671,1.797,1,12,0.937,0.234,1,3,Y,Zhang,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,8.827,1.313235,12,0.941176,1.211482,-6.12959,1.669061,27,2.055529,1.291921,2.655582,-8.78517,-3.474,Antagonistic
10,299,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body length growth,Body length/body length growth,Percent,Ecological,Organic pollutants X Ecological,Y,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,24.626,1.12,3,30,23.417,0.896,3,30,24.85,0.672,3,30,22.611,0.896,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,23.641,0.79196,30,0.987013,0.845581,1.202277,0.078712,90,1.986979,0.280557,0.557461,0.644816,1.759738,Synergistic
10,300,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body length growth,Body length/body length growth,Percent,Ecological,Organic pollutants X Ecological,Y,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,24.626,1.12,3,30,18.044,0.538,3,30,24.85,0.672,3,30,18.582,1.343,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,18.268,0.608699,30,0.987013,1.042632,-0.29725,0.067403,90,1.986979,0.259621,0.515861,-0.81311,0.218611,Additive
10,301,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body length growth,Body length/body length growth,Percent,Ecological,Organic pollutants X Ecological,Y,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,24.626,1.12,3,30,23.417,0.896,3,30,22.746,0.985,3,30,21.492,1.119,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,21.537,0.941552,30,0.987013,1.034089,0.042951,0.066682,90,1.986979,0.258229,0.513095,-0.47014,0.556046,Additive
10,302,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body length growth,Body length/body length growth,Percent,Ecological,Organic pollutants X Ecological,Y,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,24.626,1.12,3,30,18.044,0.538,3,30,22.746,0.985,3,30,18.358,0.582,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,16.164,0.793621,30,0.987013,0.695902,-3.1118,0.147361,90,1.986979,0.383876,0.762753,-3.87455,-2.34905,Antagonistic
10,307,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body weight growth,Body mass/body mass growth,Percent,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,59.761,2.143,3,30,58.571,2.381,3,30,60.357,5.119,3,30,57.142,2.619,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,59.167,3.992075,30,0.987013,3.376079,0.592018,0.069587,90,1.986979,0.263794,0.524153,0.067865,1.116172,Synergistic
10,308,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body weight growth,Body mass/body mass growth,Percent,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,59.761,2.143,3,30,49.642,1.191,3,30,60.357,5.119,3,30,45.476,1.547,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,50.238,3.716359,30,0.987013,2.846448,1.651236,0.089388,90,1.986979,0.298979,0.594064,1.057172,2.2453,Synergistic
10,309,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body weight growth,Body mass/body mass growth,Percent,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,59.761,2.143,3,30,58.571,2.381,3,30,47.857,1.547,3,30,49.642,1.191,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,46.667,2.007781,30,0.987013,1.650707,-1.77885,0.093036,90,1.986979,0.305018,0.606064,-2.38492,-1.17279,Antagonistic
10,310,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Body weight growth,Body mass/body mass growth,Percent,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,Y,60,PE,12,Undisclosed,Y,59.761,2.143,3,30,49.642,1.191,3,30,47.857,1.547,3,30,45.476,2.381,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,37.738,1.380523,30,0.987013,1.946151,-3.92442,0.195009,90,1.986979,0.441598,0.877446,-4.80186,-3.04697,Antagonistic
10,311,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 mRNA expression,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.015,0.017,3,30,1.02,0.031,3,30,0.831,0.083,3,30,0.807,0.095,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.836,0.06265,30,0.987013,0.080467,0.355714,0.067721,90,1.986979,0.260233,0.517077,-0.16136,0.872791,Additive
10,312,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 mRNA expression,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.015,0.017,3,30,0.937,0.048,3,30,0.831,0.083,3,30,0.85,0.13,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.753,0.067797,30,0.987013,0.103674,-0.92348,0.073773,90,1.986979,0.271613,0.539688,-1.46316,-0.38379,Antagonistic
10,313,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 mRNA expression,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.015,0.017,3,30,1.02,0.031,3,30,0.618,0.059,3,30,0.531,0.123,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.623,0.047127,30,0.987013,0.09314,0.974936,0.074587,90,1.986979,0.273107,0.542658,0.432278,1.517594,Synergistic
10,314,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 mRNA expression,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.015,0.017,3,30,0.937,0.048,3,30,0.618,0.059,3,30,0.548,0.125,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.54,0.053782,30,0.987013,0.096222,-0.08206,0.066723,90,1.986979,0.258308,0.513252,-0.59531,0.431191,Additive
10,315,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin mRNA expression,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,0.98,0.253,3,30,1.039,0.182,3,30,0.855,0.054,3,30,0.89,0.071,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.914,0.134239,30,0.987013,0.10738,0.220602,0.067072,90,1.986979,0.258983,0.514594,-0.29399,0.735196,Additive
10,316,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin mRNA expression,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,0.98,0.253,3,30,0.961,0.106,3,30,0.855,0.054,3,30,0.807,0.102,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.836,0.084119,30,0.987013,0.093488,0.306172,0.067448,90,1.986979,0.259707,0.516033,-0.20986,0.822204,Additive
10,317,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin mRNA expression,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,0.98,0.253,3,30,1.039,0.182,3,30,0.654,0.113,3,30,0.637,0.052,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.713,0.151481,30,0.987013,0.113249,0.662374,0.070323,90,1.986979,0.265185,0.526916,0.135458,1.18929,Synergistic
10,318,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin mRNA expression,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,0.98,0.253,3,30,0.961,0.106,3,30,0.654,0.113,3,30,0.59,0.106,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.635,0.109556,30,0.987013,0.107793,0.412047,0.068082,90,1.986979,0.260924,0.518451,-0.1064,0.930498,Additive
10,319,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin mRNA expression,claudin mRNA expression,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.061,0.088,3,30,1.007,0.214,3,30,0.724,0.055,3,30,0.744,0.052,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.67,0.156239,30,0.987013,0.116436,-0.62729,0.069946,90,1.986979,0.264473,0.525502,-1.15279,-0.10179,Antagonistic
10,320,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin mRNA expression,claudin mRNA expression,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.061,0.088,3,30,0.956,0.087,3,30,0.724,0.055,3,30,0.844,0.137,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.619,0.07278,30,0.987013,0.109695,-2.0245,0.100822,90,1.986979,0.317524,0.630914,-2.65542,-1.39359,Antagonistic
10,321,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin mRNA expression,claudin mRNA expression,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.061,0.088,3,30,1.007,0.214,3,30,0.358,0.048,3,30,0.425,0.076,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.304,0.155081,30,0.987013,0.122119,-0.97797,0.074637,90,1.986979,0.273198,0.542838,-1.52081,-0.43513,Antagonistic
10,322,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin mRNA expression,claudin mRNA expression,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.061,0.088,3,30,0.956,0.087,3,30,0.358,0.048,3,30,0.312,0.083,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.253,0.07026,30,0.987013,0.076894,-0.75732,0.071446,90,1.986979,0.267294,0.531108,-1.28843,-0.22621,Antagonistic
10,323,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mRNA expression level,Metabolic,Organic pollutants X Metabolic,Y,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,5543.31,226.77,3,30,5543.31,919.68,3,30,4661.42,377.95,3,30,4976.38,251.97,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4661.42,703.0852,30,0.987013,528.1182,-0.58864,0.069554,90,1.986979,0.263731,0.524028,-1.11266,-0.06461,Antagonistic
10,324,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mRNA expression level,Metabolic,Organic pollutants X Metabolic,Y,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,5543.31,226.77,3,30,5581.1,566.93,3,30,4661.42,377.95,3,30,4913.39,377.95,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4699.21,481.7965,30,0.987013,432.9978,-0.48822,0.068653,90,1.986979,0.262017,0.520623,-1.00884,0.032402,Additive
10,325,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mRNA expression level,Metabolic,Organic pollutants X Metabolic,Y,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,5543.31,226.77,3,30,5543.31,919.68,3,30,4447.24,188.98,3,30,4157.48,226.77,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4447.24,663.8994,30,0.987013,496.0781,0.576516,0.069436,90,1.986979,0.263508,0.523585,0.052931,1.1001,Synergistic
10,326,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mRNA expression level,Metabolic,Organic pollutants X Metabolic,Y,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,5543.31,226.77,3,30,5581.1,566.93,3,30,4447.24,188.98,3,30,4283.46,188.98,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4485.03,422.5654,30,0.987013,327.3186,0.607824,0.069745,90,1.986979,0.264094,0.524748,0.083076,1.132573,Synergistic
10,327,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Distance,Total distance moved,mm,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,19572.4,2631.5,3,30,18585.5,1315.8,3,30,16940.8,328.9,3,30,13651.3,657.9,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,15953.9,959.0372,30,0.987013,822.37,2.763593,0.130312,90,1.986979,0.360988,0.717275,2.046318,3.480868,Synergistic
10,328,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Distance,Total distance moved,mm,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,19572.4,2631.5,3,30,16282.9,986.8,3,30,16940.8,328.9,3,30,15953.9,1480.3,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,13651.3,735.5098,30,0.987013,1168.816,-1.94444,0.098174,90,1.986979,0.313327,0.622574,-2.56702,-1.32187,Antagonistic
10,329,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Distance,Total distance moved,mm,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,19572.4,2631.5,3,30,18585.5,1315.8,3,30,13157.9,1151.3,3,30,14144.7,822.4,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,12171,1236.289,30,0.987013,1049.941,-1.85541,0.095354,90,1.986979,0.308795,0.613569,-2.46898,-1.24184,Antagonistic
10,330,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Distance,Total distance moved,mm,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,19572.4,2631.5,3,30,16282.9,986.8,3,30,13157.9,1151.3,3,30,13651.3,1480.3,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,9868.4,1072.209,30,0.987013,1292.463,-2.88888,0.136214,90,1.986979,0.369071,0.733337,-3.62222,-2.15554,Antagonistic
10,331,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Swimming speed,Swimming speed,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,107.566,20.723,3,30,102.632,9.868,3,30,94.736,4.935,3,30,75.986,3.948,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,89.802,7.801655,30,0.987013,6.182739,2.205587,0.107205,90,1.986979,0.327422,0.65058,1.555007,2.856168,Synergistic
10,332,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Swimming speed,Swimming speed,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,107.566,20.723,3,30,89.802,8.882,3,30,94.736,4.935,3,30,90.789,6.908,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,76.972,7.18485,30,0.987013,7.047785,-1.93501,0.097869,90,1.986979,0.31284,0.621607,-2.55662,-1.31341,Antagonistic
10,333,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Swimming speed,Swimming speed,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,107.566,20.723,3,30,102.632,9.868,3,30,74.013,11.842,3,30,78.947,3.947,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,69.079,10.89978,30,0.987013,8.197073,-1.18821,0.078432,90,1.986979,0.280057,0.556468,-1.74468,-0.63174,Antagonistic
10,334,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Swimming speed,Swimming speed,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,107.566,20.723,3,30,89.802,8.882,3,30,74.013,11.842,3,30,72.039,13.816,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,56.249,10.46716,30,0.987013,12.25649,-1.27157,0.080141,90,1.986979,0.283091,0.562496,-1.83406,-0.70907,Antagonistic
10,335,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mean accelaration,Accelaration,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,125.166,8.344,3,30,137.086,11.921,3,30,101.325,5.96,3,30,100.132,17.881,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,113.245,9.42422,30,0.987013,14.29241,0.905565,0.0735,90,1.986979,0.27111,0.538689,0.366876,1.444253,Synergistic
10,336,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mean accelaration,Accelaration,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,125.166,8.344,3,30,119.205,9.537,3,30,101.325,5.96,3,30,75.099,11.92,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,95.364,7.952231,30,0.987013,10.13224,1.974078,0.099142,90,1.986979,0.314867,0.625635,1.348443,2.599712,Synergistic
10,337,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mean accelaration,Accelaration,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,125.166,8.344,3,30,137.086,11.921,3,30,65.562,13.113,3,30,98.94,9.537,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,77.482,12.53118,30,0.987013,11.13519,-1.90202,0.096814,90,1.986979,0.311149,0.618247,-2.52026,-1.28377,Antagonistic
10,338,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mean accelaration,Accelaration,mm/s,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,125.166,8.344,3,30,119.205,9.537,3,30,65.562,13.113,3,30,76.291,8.344,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,59.601,11.46528,30,0.987013,10.02684,-1.64292,0.08916,90,1.986979,0.298596,0.593305,-2.23622,-1.04961,Antagonistic
10,339,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Number of interactions,Number of interactions,NA,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,184.768,9.934,3,30,166.887,21.855,3,30,150.993,29.802,3,30,194.702,19.868,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,133.112,26.13236,30,0.987013,23.21247,-2.61886,0.12382,90,1.986979,0.351881,0.69918,-3.31804,-1.91968,Antagonistic
10,340,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Number of interactions,Number of interactions,NA,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,184.768,9.934,3,30,218.543,21.854,3,30,150.993,29.802,3,30,236.424,21.854,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,184.768,26.13194,30,0.987013,24.08813,2.116609,0.104,90,1.986979,0.322491,0.640782,1.475827,2.757391,Synergistic
10,341,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Number of interactions,Number of interactions,NA,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,184.768,9.934,3,30,166.887,21.855,3,30,230.464,31.788,3,30,170.861,15.894,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,212.583,27.27744,30,0.987013,22.32351,-1.8447,0.095024,90,1.986979,0.30826,0.612506,-2.45721,-1.23219,Antagonistic
10,342,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Number of interactions,Number of interactions,NA,Ecological,Organic pollutants X Ecological,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,184.768,9.934,3,30,218.543,21.854,3,30,230.464,31.788,3,30,145.033,17.881,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,264.239,27.27704,30,0.987013,23.0626,-5.10167,0.283559,90,1.986979,0.532503,1.058071,-6.15974,-4.0436,Antagonistic
10,343,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Villus height,Villus height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,911.765,22.059,3,30,647.059,22.059,3,30,786.765,22.059,3,30,691.176,29.412,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,522.059,22.059,30,0.987013,25.99678,-6.42082,0.410225,90,1.986979,0.640488,1.272635,-7.69346,-5.14819,Antagonistic
10,344,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Villus height,Villus height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,911.765,22.059,3,30,698.529,58.824,3,30,786.765,22.059,3,30,757.353,22.059,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,573.529,44.42332,30,0.987013,35.07157,-5.17333,0.289694,90,1.986979,0.538232,1.069456,-6.24278,-4.10387,Antagonistic
10,345,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Villus height,Villus height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,911.765,22.059,3,30,647.059,22.059,3,30,750,14.706,3,30,786.765,29.411,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,485.294,18.74655,30,0.987013,24.66212,-12.0653,1.279762,90,1.986979,1.131266,2.247801,-14.3131,-9.8175,Antagonistic
10,346,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Villus height,Villus height,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,911.765,22.059,3,30,698.529,58.824,3,30,750,14.706,3,30,610.294,22.059,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,536.764,42.87499,30,0.987013,34.09446,-2.12865,0.104426,90,1.986979,0.32315,0.642093,-2.77074,-1.48655,Antagonistic
10,347,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Muscle thickness,Muscle thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,83.088,7.353,3,30,79.411,2.206,3,30,80.147,3.676,3,30,75,5.147,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,76.47,3.031453,30,0.987013,4.22382,0.343506,0.06765,90,1.986979,0.260096,0.516805,-0.1733,0.860312,Additive
10,348,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Muscle thickness,Muscle thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,83.088,7.353,3,30,77.205,9.559,3,30,80.147,3.676,3,30,77.941,8.088,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,74.264,7.241804,30,0.987013,7.676571,-0.47277,0.068529,90,1.986979,0.261781,0.520153,-0.99292,0.047384,Additive
10,349,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Muscle thickness,Muscle thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,83.088,7.353,3,30,79.411,2.206,3,30,69.852,5.148,3,30,64.705,7.353,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,66.175,3.960324,30,0.987013,5.905539,0.245686,0.06717,90,1.986979,0.259171,0.514968,-0.26928,0.760654,Additive
10,350,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Muscle thickness,Muscle thickness,Micro m,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,83.088,7.353,3,30,77.205,9.559,3,30,69.852,5.148,3,30,63.235,6.617,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,63.969,7.677121,30,0.987013,7.16669,0.101088,0.066752,90,1.986979,0.258364,0.513363,-0.41228,0.614451,Additive
10,351,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mucus secretion coverage,Mucus secretion coverage,Percent,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,8.455,0.515,3,30,7.941,0.367,3,30,7.867,0.588,3,30,7.058,0.589,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,7.353,0.490119,30,0.987013,0.54182,0.53739,0.069073,90,1.986979,0.262818,0.522214,0.015177,1.059604,Synergistic
10,352,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mucus secretion coverage,Mucus secretion coverage,Percent,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,8.455,0.515,3,30,6.397,0.588,3,30,7.867,0.588,3,30,6.47,0.735,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.809,0.588,30,0.987013,0.665571,-0.98023,0.074674,90,1.986979,0.273265,0.542972,-1.52321,-0.43726,Antagonistic
10,353,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mucus secretion coverage,Mucus secretion coverage,Percent,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,8.455,0.515,3,30,7.941,0.367,3,30,6.691,0.588,3,30,5.367,0.809,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,6.177,0.490119,30,0.987013,0.668841,1.195322,0.078573,90,1.986979,0.280309,0.556969,0.638353,1.75229,Synergistic
10,354,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,,Mucus secretion coverage,Mucus secretion coverage,Percent,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,8.455,0.515,3,30,6.397,0.588,3,30,6.691,0.588,3,30,6.102,0.736,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4.633,0.588,30,0.987013,0.666123,-2.17666,0.106149,90,1.986979,0.325805,0.647367,-2.82402,-1.52929,Antagonistic
10,355,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 transcription,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.028,0.098,3,30,0.917,0.022,3,30,1.002,0.142,3,30,0.771,0.055,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.891,0.101607,30,0.987013,0.081698,1.449755,0.084182,90,1.986979,0.290141,0.576503,0.873252,2.026259,Synergistic
10,356,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 transcription,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.028,0.098,3,30,0.577,0.087,3,30,1.002,0.142,3,30,0.562,0.055,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.551,0.117756,30,0.987013,0.091901,-0.11814,0.066783,90,1.986979,0.258424,0.513483,-0.63162,0.395343,Additive
10,357,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 transcription,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.028,0.098,3,30,0.917,0.022,3,30,0.725,0.087,3,30,0.527,0.043,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.614,0.063455,30,0.987013,0.054201,1.58429,0.087583,90,1.986979,0.295944,0.588035,0.996255,2.172325,Synergistic
10,358,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,ZO-1 transcription,ZO-1 expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.028,0.098,3,30,0.577,0.087,3,30,0.725,0.087,3,30,0.515,0.065,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.274,0.087,30,0.987013,0.076792,-3.09759,0.146626,90,1.986979,0.382917,0.760849,-3.85844,-2.33674,Antagonistic
10,359,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin transcription,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.04,0.043,3,30,0.93,0.033,3,30,1.072,0.121,3,30,0.733,0.121,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.962,0.088685,30,0.987013,0.10608,2.130709,0.104499,90,1.986979,0.323264,0.642318,1.488391,2.773027,Synergistic
10,360,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin transcription,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.04,0.043,3,30,0.635,0.054,3,30,1.072,0.121,3,30,0.613,0.12,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.667,0.093694,30,0.987013,0.107653,0.495095,0.068709,90,1.986979,0.262125,0.520836,-0.02574,1.015932,Additive
10,361,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin transcription,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.04,0.043,3,30,0.93,0.033,3,30,0.854,0.087,3,30,0.678,0.066,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.744,0.065795,30,0.987013,0.065898,0.988546,0.07481,90,1.986979,0.273515,0.543468,0.445078,1.532014,Synergistic
10,362,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,occludin transcription,occludin expression/transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.04,0.043,3,30,0.635,0.054,3,30,0.854,0.087,3,30,0.492,0.077,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.449,0.072405,30,0.987013,0.074738,-0.56787,0.069354,90,1.986979,0.263351,0.523274,-1.09115,-0.0446,Antagonistic
10,363,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin-2 transcription,claudin-2 transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.007,0.076,3,30,0.744,0.044,3,30,0.908,0.055,3,30,0.514,0.077,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.645,0.049805,30,0.987013,0.064844,1.993995,0.0998,90,1.986979,0.315912,0.62771,1.366285,2.621705,Synergistic
10,364,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin-2 transcription,claudin-2 transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.007,0.076,3,30,0.777,0.066,3,30,0.908,0.055,3,30,0.262,0.121,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.678,0.060749,30,0.987013,0.095738,4.288764,0.219946,90,1.986979,0.468984,0.931861,3.356904,5.220625,Synergistic
10,365,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin-2 transcription,claudin-2 transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.007,0.076,3,30,0.744,0.044,3,30,0.361,0.098,3,30,0.437,0.132,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.098,0.075961,30,0.987013,0.107689,-3.10706,0.147115,90,1.986979,0.383556,0.762118,-3.86918,-2.34494,Antagonistic
10,366,"Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)",Organic pollutants,Herbicides,Glyphosate,3,60 d,claudin-2 transcription,claudin-2 transcription,mRNA expression level,Metabolic,Organic pollutants X Metabolic,N,3,mg/L,mg/L,N,60,PE,12,Undisclosed,Y,1.007,0.076,3,30,0.777,0.066,3,30,0.361,0.098,3,30,0.229,0.055,3,30,Y,Chen,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.131,0.083546,30,0.987013,0.070728,-1.36759,0.082252,90,1.986979,0.286797,0.569859,-1.93745,-0.79773,Antagonistic
11,370,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,166.705,1.431,3,15,163.636,3.069,3,15,135.614,3.477,3,15,169.159,6.136,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,132.545,3.279351,15,0.972973,4.919585,-7.24135,1.007285,45,2.015368,1.003636,2.022696,-9.26404,-5.21865,Antagonistic
11,371,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,166.705,1.431,3,15,163.636,3.069,3,15,89.386,4.091,3,15,132.545,4.91,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,86.317,3.616286,15,0.972973,4.311938,-10.4312,1.946825,45,2.015368,1.395287,2.812015,-13.2432,-7.61916,Antagonistic
11,372,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,166.705,1.431,3,15,163.636,3.069,3,15,33.136,2.25,3,15,82.431,3.069,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,30.067,2.690842,15,0.972973,2.886121,-17.653,5.327152,45,2.015368,2.308062,4.651594,-22.3046,-13.0014,Antagonistic
11,376,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,25.329,0.776,3,15,35.383,1.726,3,15,15.318,1.898,3,15,23.905,2.848,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,25.372,1.81404,15,0.972973,2.38766,-0.5978,0.139289,45,2.015368,0.373215,0.752166,-1.34997,0.154362,Additive
11,377,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,25.329,0.776,3,15,35.383,1.726,3,15,11.952,0.647,3,15,17.907,3.322,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,22.006,1.303397,15,0.972973,2.523344,1.580528,0.174968,45,2.015368,0.418292,0.843011,0.737517,2.42354,Synergistic
11,378,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,25.329,0.776,3,15,35.383,1.726,3,15,3.452,0.215,3,15,6.472,0.82,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,13.506,1.229899,15,0.972973,1.045239,6.547679,0.847868,45,2.015368,0.920798,1.855746,4.691933,8.403425,Synergistic
11,382,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,42.197,1.248,3,15,50.624,2.746,3,15,26.591,0.312,3,15,33.146,4.494,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,35.018,1.954208,15,0.972973,3.465182,0.525631,0.137938,45,2.015368,0.3714,0.748508,-0.22288,1.274139,Additive
11,383,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,42.197,1.248,3,15,50.624,2.746,3,15,13.42,1.311,3,15,25.343,2.497,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,21.847,2.151655,15,0.972973,2.330732,-1.45942,0.168832,45,2.015368,0.410891,0.828097,-2.28752,-0.63132,Antagonistic
11,384,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,42.197,1.248,3,15,50.624,2.746,3,15,4.993,1.124,3,15,8.302,0.624,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,13.42,2.098082,15,0.972973,1.547792,3.217276,0.305848,45,2.015368,0.553035,1.114569,2.102707,4.331845,Synergistic
11,388,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Malondialdehyde content,Malondialdehyde levels,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,2.656,0.226,3,15,1.378,0.243,3,15,3.971,0.335,3,15,2.668,0.218,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,2.693,0.292638,15,0.972973,0.258032,-0.09427,0.133481,45,2.015368,0.365351,0.736317,-0.83059,0.642048,Additive
11,389,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Malondialdehyde content,Malondialdehyde levels,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,2.656,0.226,3,15,1.378,0.243,3,15,5.739,0.252,3,15,3.724,0.268,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,4.461,0.247541,15,0.972973,0.257973,-2.77967,0.26211,45,2.015368,0.511966,1.0318,-3.81147,-1.74787,Antagonistic
11,390,Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish,Organic pollutants,Fungicides,Difenoconazole,4,8 d,Malondialdehyde content,Malondialdehyde levels,U/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,mg/L,Y,8,PS,10,Undisclosed,Y,2.656,0.226,3,15,1.378,0.243,3,15,6.4,0.445,3,15,5.207,0.209,3,15,Y,Li,2022,Danio rerio,Danionidae,Adult,Benthopelagic,5.122,0.358521,15,0.972973,0.293443,0.281835,0.134657,45,2.015368,0.366957,0.739553,-0.45772,1.021388,Additive
12,391,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 weight,Body mass/body mass growth,mg,Biochemical,Inorganic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,4.67,0.131,3,60,4.09,0.069,3,60,4.329,0.131,3,60,3.494,0.113,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,3.749,0.104695,60,0.993631,0.108927,2.326115,0.055878,180,1.973305,0.236386,0.466462,1.859653,2.792577,Synergistic
12,392,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 weight,Body mass/body mass growth,mg,Biochemical,Inorganic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,4.67,0.131,3,60,4.09,0.069,3,60,4.545,0.142,3,60,4.659,0.17,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,3.965,0.111636,60,0.993631,0.14381,-4.79508,0.129137,180,1.973305,0.359356,0.709119,-5.5042,-4.08596,Antagonistic
12,393,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 weight,Body mass/body mass growth,mg,Ecological,Inorganic pollutants X Ecological,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,4.5,0.142,3,60,4.431,0.267,3,60,4.471,0.199,3,60,3.42,0.17,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,4.402,0.235468,60,0.993631,0.205359,4.751402,0.127399,180,1.973305,0.35693,0.704333,4.047069,5.455734,Synergistic
12,394,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 weight,Body mass/body mass growth,mg,Ecological,Inorganic pollutants X Ecological,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,4.5,0.142,3,60,4.431,0.267,3,60,4.443,0.085,3,60,4.471,0.102,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,4.374,0.198134,60,0.993631,0.157577,-0.61165,0.034892,180,1.973305,0.186794,0.368602,-0.98025,-0.24305,Antagonistic
12,395,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 body length,Body length/body length growth,cm,Ecological,Inorganic pollutants X Ecological,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.959,0.026,3,60,0.784,0.031,3,60,0.818,0.048,3,60,0.679,0.021,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.643,0.040404,60,0.993631,0.032199,-1.11094,0.038476,180,1.973305,0.196152,0.387069,-1.49801,-0.72387,Antagonistic
12,396,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 body length,Body length/body length growth,cm,Ecological,Inorganic pollutants X Ecological,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.959,0.026,3,60,0.784,0.031,3,60,0.921,0.026,3,60,1.007,0.034,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.746,0.028609,60,0.993631,0.031421,-8.25376,0.317186,180,1.973305,0.563192,1.111351,-9.36511,-7.14241,Antagonistic
12,397,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 body length,Body length/body length growth,cm,Ecological,Inorganic pollutants X Ecological,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.964,0.065,3,60,0.897,0.042,3,60,0.965,0.031,3,60,0.701,0.031,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.898,0.036912,60,0.993631,0.034084,5.742947,0.170756,180,1.973305,0.413226,0.815422,4.927526,6.558369,Synergistic
12,398,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 body length,Body length/body length growth,cm,Ecological,Inorganic pollutants X Ecological,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.964,0.065,3,60,0.897,0.042,3,60,0.902,0.034,3,60,1.022,0.08,3,60,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.835,0.03821,60,0.993631,0.06269,-2.96395,0.069937,180,1.973305,0.264457,0.521854,-3.4858,-2.44209,Antagonistic
12,399,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 reactive oxygen species,Reactive oxygen species,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.985,0.103,3,3,1.305,0.117,3,3,1.732,0.123,3,3,2.385,0.124,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,2.052,0.120037,3,0.8,0.122035,2.182983,1.063785,9,2.306004,1.031399,2.378411,-0.19543,4.561395,Additive
12,400,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 reactive oxygen species,Reactive oxygen species,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.985,0.103,3,3,1.305,0.117,3,3,1.08,0.089,3,3,0.896,0.048,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.4,0.103947,3,0.8,0.08096,-4.98025,2.73357,9,2.306004,1.653351,3.812635,-8.79288,-1.16761,Antagonistic
12,401,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 reactive oxygen species,Reactive oxygen species,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,1.001,0.151,3,3,1.173,0.035,3,3,1.222,0.045,3,3,1.052,0.123,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.394,0.040311,3,0.8,0.091526,-2.98932,1.411334,9,2.306004,1.187996,2.739523,-5.72884,-0.24979,Antagonistic
12,402,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 reactive oxygen species,Reactive oxygen species,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,1.001,0.151,3,3,1.173,0.035,3,3,1.003,0.117,3,3,1.097,0.138,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.175,0.086354,3,0.8,1.15E-01,-0.54209,0.691155,9,2.306004,0.831357,1.917113,-2.4592,1.375027,Additive
12,403,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 malondialdehyde levels,Malondialdehyde levels,nmols/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.727,0.048,3,3,0.909,0.085,3,3,1.721,0.171,3,3,2.053,0.219,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.903,0.13503,3,0.8,0.181926,0.65961,0.702924,9,2.306004,0.838405,1.933366,-1.27376,2.592976,Additive
12,404,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 malondialdehyde levels,Malondialdehyde levels,nmols/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.727,0.048,3,3,0.909,0.085,3,3,0.909,0.065,3,3,1.125,0.161,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.091,0.075664,3,0.8,0.12579,0.216234,0.670563,9,2.306004,0.818879,1.888339,-1.6721,2.104573,Additive
12,405,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 malondialdehyde levels,Malondialdehyde levels,nmols/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.823,0.074,3,3,0.84,0.114,3,3,0.823,0.074,3,3,0.965,0.066,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.84,0.096104,3,0.8,0.082438,1.213035,0.789288,9,2.306004,0.888419,2.048697,-0.83566,3.261732,Additive
12,406,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 malondialdehyde levels,Malondialdehyde levels,nmols/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.823,0.074,3,3,0.84,0.114,3,3,0.803,0.037,3,3,0.755,0.04,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.82,0.08475,3,0.8,0.066267,0.78471,0.717981,9,2.306004,0.847337,1.953964,-1.16925,2.738674,Additive
12,407,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 total antioxidant capacity,Total antioxidant capacity,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.993,0.022,3,3,0.796,0.045,3,3,1.039,0.021,3,3,0.656,0.069,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.842,0.035114,3,0.8,5.47E-02,2.718063,1.282322,9,2.306004,1.132397,2.611312,0.106752,5.329375,Synergistic
12,408,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 total antioxidant capacity,Total antioxidant capacity,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.993,0.022,3,3,0.796,0.045,3,3,0.994,0.027,3,3,1.021,0.009,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.797,0.037108,3,0.8,0.027,-6.63704,4.337522,9,2.306004,2.082672,4.80265,-11.4397,-1.83439,Antagonistic
12,409,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 total antioxidant capacity,Total antioxidant capacity,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.927,0.054,3,3,0.914,0.085,3,3,0.933,0.062,3,3,0.565,0.063,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.92,0.074394,3,0.8,0.068933,4.119946,2.081163,9,2.306004,1.442624,3.326696,0.79325,7.446642,Synergistic
12,410,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 total antioxidant capacity,Total antioxidant capacity,Relative level,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.927,0.054,3,3,0.914,0.085,3,3,0.91,0.071,3,3,0.933,0.058,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.897,0.078313,3,0.8,0.068909,-0.41794,0.681223,9,2.306004,0.825362,1.903289,-2.32123,1.485348,Additive
12,415,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Mn-superoxide dismutase activity,Mn-SOD activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,25.238,2.805,3,3,27.028,1.79,3,3,25.059,3.282,3,3,19.57,1.909,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,26.849,2.643447,3,0.8,2.305655,-2.52562,1.198228,9,2.306004,1.094636,2.524235,-5.04985,-0.00138,Antagonistic
12,416,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Mn-superoxide dismutase activity,Mn-SOD activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,25.238,2.805,3,3,27.028,1.79,3,3,39.26,1.193,3,3,25.835,2.506,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,41.05,1.521077,3,0.8,2.072886,-5.87201,3.540039,9,2.306004,1.881499,4.338745,-10.2108,-1.53326,Antagonistic
12,417,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Mn-superoxide dismutase activity,Mn-SOD activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,23.568,1.193,3,3,24.463,2.088,3,3,24.642,1.491,3,3,24.164,1.373,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,25.537,1.814225,3,0.8,1.60881,-0.68274,0.705511,9,2.306004,0.839947,1.936922,-2.61966,1.254181,Additive
12,418,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Mn-superoxide dismutase activity,Mn-SOD activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,23.568,1.193,3,3,24.463,2.088,3,3,26.551,1.79,3,3,28.043,2.088,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,27.446,1.944716,3,0.8,2.017631,0.236713,0.671336,9,2.306004,0.819351,1.889427,-1.65271,2.12614,Additive
12,419,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,22.379,1.002,3,3,15.689,0.967,3,3,17.664,0.966,3,3,12.914,1.073,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,10.974,0.9665,3,0.8,1.021139,-1.51987,0.859167,9,2.306004,0.926913,2.137465,-3.65734,0.617594,Additive
12,420,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,22.379,1.002,3,3,15.689,0.967,3,3,20.963,1.79,3,3,19.648,0.788,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,14.273,1.438609,3,0.8,1.159857,-3.70735,1.812038,9,2.306004,1.34612,3.104158,-6.81151,-0.60319,Antagonistic
12,421,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,23.668,1.181,3,3,24.03,2.328,3,3,23.857,1.969,3,3,14.739,1.074,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,24.219,2.155985,3,0.8,1.703195,-4.45281,2.318958,9,2.306004,1.522812,3.511612,-7.96442,-0.9412,Antagonistic
12,422,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,23.668,1.181,3,3,24.03,2.328,3,3,24.041,2.077,3,3,24.876,1.683,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,24.403,2.206073,3,0.8,1.962046,0.19286,0.669766,9,2.306004,0.818392,1.887216,-1.69436,2.080076,Additive
12,423,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 3 activity,Caspase 3 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.969,0.146,3,3,0.987,0.085,3,3,1.502,0.197,3,3,2.42,0.352,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.52,0.151714,3,0.8,0.271036,2.656474,1.254738,9,2.306004,1.120151,2.583072,0.073402,5.239546,Synergistic
12,424,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 3 activity,Caspase 3 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.969,0.146,3,3,0.987,0.085,3,3,0.884,0.086,3,3,1.057,0.171,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,0.902,0.085501,3,0.8,0.135188,-0.91724,0.736778,9,2.306004,0.858358,1.979376,-2.89662,1.062134,Additive
12,425,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 8 activity,Caspase 8 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.989,0.154,3,3,2.019,0.128,3,3,1.65,0.129,3,3,2.989,0.12,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,2.68,0.128501,3,0.8,0.124323,1.988366,0.996133,9,2.306004,0.998065,2.301542,-0.31318,4.289908,Additive
12,426,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 8 activity,Caspase 8 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.989,0.154,3,3,2.019,0.128,3,3,0.947,0.06,3,3,1.094,0.137,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.977,0.09996,3,0.8,0.119919,-5.89066,3.558319,9,2.306004,1.886351,4.349933,-10.2406,-1.54072,Antagonistic
12,427,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 9 activity,Caspase 9 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.992,0.129,3,3,2.262,0.145,3,3,2.348,0.291,3,3,4.278,0.318,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,3.618,0.229898,3,0.8,0.277468,1.902922,0.968426,9,2.306004,0.984086,2.269307,-0.36639,4.172229,Additive
12,428,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F0 Caspase 9 activity,Caspase 9 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.992,0.129,3,3,2.262,0.145,3,3,0.95,0.06,3,3,1.826,0.111,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,2.22,0.110962,3,0.8,0.110981,-2.84013,1.338861,9,2.306004,1.157092,2.668258,-5.50839,-0.17187,Antagonistic
12,429,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 3 activity,Caspase 3 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.978,0.248,3,3,1.021,0.077,3,3,1.193,0.103,3,3,1.099,0.112,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.236,0.090934,3,0.8,0.102012,-1.07438,0.762858,9,2.306004,0.873417,2.014104,-3.08848,0.939723,Additive
12,430,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 3 activity,Caspase 3 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.978,0.248,3,3,1.021,0.077,3,3,1.022,0.128,3,3,1.065,0.172,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.065,0.105624,3,0.8,0.142724,-1.24E-15,0.666667,9,2.306004,0.816497,1.882844,-1.88284,1.882844,Additive
12,431,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 8 activity,Caspase 8 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.98,0.172,3,3,1.024,0.128,3,3,1.058,0.223,3,3,1.102,0.137,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.102,0.181814,3,0.8,0.160974,1.10E-15,0.666667,9,2.306004,0.816497,1.882844,-1.88284,1.882844,Additive
12,432,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 8 activity,Caspase 8 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.98,0.172,3,3,1.024,0.128,3,3,1.11,0.163,3,3,1.103,0.128,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.154,0.146549,3,0.8,0.137587,-0.29654,0.673995,9,2.306004,0.820972,1.893164,-2.1897,1.596625,Additive
12,433,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 9 activity,Caspase 9 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.983,0.103,3,3,1.061,0.223,3,3,1.027,0.12,3,3,0.942,0.146,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.105,0.179066,3,0.8,0.163372,-0.79818,0.719758,9,2.306004,0.848385,1.95638,-2.75456,1.158199,Additive
12,434,Particles rather than released Zn2+ from ZnO nanoparticles aggravate microplastics toxicity in early stages of exposed zebrafish and their unexposed offspring,Inorganic pollutants,Metal contaminants,Zinc,5,,F1 Caspase 9 activity,Caspase 9 activity,NA,Metabolic,Inorganic pollutants X Metabolic,N,2,Micro g/L,Micro g/L,N,30,PS,5,Spheres,Y,0.983,0.103,3,3,1.061,0.223,3,3,1.087,0.129,3,3,1.071,0.215,3,3,Y,Zheng,2022,Danio rerio,Danionidae,Embryos and larvae,Benthopelagic,1.165,0.182168,3,0.8,0.199261,-0.37739,0.678536,9,2.306004,0.823733,1.899531,-2.27693,1.522137,Additive
13,447,Effects of microplastics on the accumulation and neurotoxicity of methylmercury in zebrafish larvae,Inorganic pollutants,Metal contaminants,Mercury,2,168 h,Survival rate,Survival rate,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,Y,7,PS,5,Undisclosed,N,85.948,2.576,3,180,72.131,4.684,3,180,74.941,4.215,3,180,73.536,6.323,3,180,Y,Zhu,2022,Danio rerio,Danionidae,Larvae,Benthopelagic,61.124,4.455675,180,0.997904,5.469615,-2.26451,0.018233,540,1.964375,0.135031,0.265251,-2.52976,-1.99926,Antagonistic
13,448,Effects of microplastics on the accumulation and neurotoxicity of methylmercury in zebrafish larvae,Inorganic pollutants,Metal contaminants,Mercury,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,Fold-change,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,Micro g/L,Y,7,PS,5,Undisclosed,N,0.995,0.062,6,120,1.052,0.038,6,120,1.076,0.051,6,120,1.297,0.014,6,120,Y,Zhu,2022,Danio rerio,Danionidae,Larvae,Benthopelagic,1.133,0.044972,120,0.996845,0.033305,4.908592,0.066863,360,1.966594,0.258579,0.50852,4.400072,5.417112,Synergistic
14,450,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Superoxide dismutase level (liver),Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,101.647,2.259,3,3,93.458,6.212,3,3,98.823,3.953,3,3,87.247,3.105,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,90.634,5.206494,3,0.8,4.286525,0.63212,0.699965,9,2.306004,0.836639,1.929293,-1.29717,2.561413,Additive
14,451,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Malondialdehyde level (liver),Malondialdehyde levels,nmol/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,2.842,0.62,3,3,5.813,1.447,3,3,5.09,1.602,3,3,5.426,1.886,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,8.061,1.526469,3,0.8,1.715678,-1.22867,0.792469,9,2.306004,0.890207,2.052822,-3.28149,0.824153,Additive
14,452,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Metallothionein level (liver),Metallothionein level,Micro g/g,Biochemical,Inorganic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,6.845,0.225,3,3,6.845,0.478,3,3,7.436,0.225,3,3,8.676,0.901,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,7.436,0.37357,3,0.8,0.689694,1.438319,0.839063,9,2.306004,0.916004,2.112309,-0.67399,3.550628,Additive
14,453,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Superoxide dismutase level (gut),Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,98.591,7.747,3,3,105.282,17.605,3,3,82.746,4.93,3,3,116.901,19.367,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,89.437,12.92751,3,0.8,16.46513,-1.33441,0.815054,9,2.306004,0.902803,2.081868,-3.41628,0.74746,Additive
14,454,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Malondialdehyde level (gut),Malondialdehyde levels,nmol/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,2.927,0.376,3,3,2.193,0.118,3,3,3.395,0.494,3,3,3.072,0.317,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,2.661,0.359138,3,0.8,0.338725,-0.9707,0.745188,9,2.306004,0.863243,1.990641,-2.96134,1.019942,Additive
14,455,Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish,Inorganic pollutants,Metal contaminants,Copper,2,,Metallothionein level (gut),Metallothionein level,Micro g/g,Biochemical,Inorganic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,N,14,PS,20,Undisclosed,N,6.816,0.507,3,3,6.732,0.422,3,3,7.661,0.198,3,3,7.295,0.592,3,3,Y,Qiao et,2019,Danio rerio,Danionidae,Adult,Benthopelagic,7.577,0.329612,3,0.8,0.479118,-0.47087,0.685143,9,2.306004,0.827734,1.908757,-2.37962,1.437892,Additive
15,456,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Hatching rate,Hatching rate,Percent,Ecological,Organic pollutants X Ecological,N,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,96.372,4.651,3,60,96.372,5.023,3,60,57.674,2.791,3,60,56.372,7.814,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,57.674,4.063263,60,0.993631,6.227708,0.207734,0.033513,180,1.973305,0.183066,0.361245,-0.15351,0.568979,Additive
15,457,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Heart rate,Heart rate,bpm,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,142.957,2.798,3,60,142.997,5.302,3,60,137.107,3.561,3,60,134.308,5.342,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,137.147,4.516189,6.00E+01,0.993631,4.946359,0.570302,0.034689,180,1.973305,0.186249,0.367525,0.202777,0.937827,Synergistic
15,458,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Malformation rate,Malformation rate,Percent,Metabolic,Organic pollutants X Metabolic,N,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,14.583,1.775,3,60,17.206,2.547,3,60,20.833,2.932,3,60,27.006,3.24,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,23.456,2.746255,6.00E+01,0.993631,3.003291,1.174508,0.039081,180,1.973305,0.197689,0.390102,0.784406,1.564609,Synergistic
15,459,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Triiodothyronine level,Triiodothyronine level,micro g/g,Biochemical,Organic pollutants X Biochemical,N,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,0.34,0.074,3,60,0.334,0.083,3,60,0.213,0.064,3,60,0.173,0.012,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.207,0.074111,60,0.993631,0.053087,0.636376,0.035021,180,1.973305,0.187138,0.369281,0.267096,1.005657,Synergistic
15,460,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Thyroxine level,Thyroxine level,micro g/g,Biochemical,Organic pollutants X Biochemical,N,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,3.117,0.175,3,60,3.029,0.161,3,60,4.492,0.22,3,60,5.048,0.761,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,4.404,0.192771,60,0.993631,0.555104,1.152753,0.03887,180,1.973305,0.197155,0.389047,0.763706,1.5418,Synergistic
15,461,Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish,Organic pollutants,Antioxidants,Butylated hydroxyanisole,2,,Thyroid stimulating hormone level,Thyroid stimulating hormone level,Mu/g,Biochemical,Organic pollutants X Biochemical,N,2,mg/L,mg/L,N,7,PS,20,Undisclosed,N,0.462,0.067,3,60,0.54,0.069,3,60,0.808,0.038,3,60,0.89,0.14,3,60,Y,Zhao,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.886,0.0557,60,0.993631,0.106542,0.037305,0.033339,180,1.973305,0.18259,0.360306,-0.323,0.397611,Additive
16,462,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,4,Micro g/L,Micro g/L,N,28,PP,60,Pellet,N,182.135,6.728,3,3,156.381,6.032,3,3,147.1,6.032,3,3,120.418,8.816,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,121.346,6.032,3,0.8,7.553373,0.098287,0.667472,9,2.306004,0.816989,1.883981,-1.78569,1.982268,Additive
16,463,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,4,Micro g/L,Micro g/L,N,28,PE,60,Pellet,N,182.135,6.728,3,3,172.158,11.137,3,3,147.1,6.032,3,3,142.459,3.481,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,137.123,8.955942,3,0.8,6.794345,-0.62829,0.699562,9,2.306004,0.836398,1.928738,-2.55703,1.300451,Additive
16,464,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,4,Micro g/L,Micro g/L,N,28,PVC,60,Pellet,N,182.135,6.728,3,3,160.557,10.441,3,3,147.1,6.032,3,3,143.619,8.121,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,125.522,8.526415,3,0.8,8.326175,-1.73881,0.91862,9,2.306004,0.958447,2.210182,-3.94899,0.471377,Additive
16,465,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Malondialdehyde level,Malondialdehyde levels,nmol/mg,Stress response,Organic pollutants X Stress response,N,4,Micro g/L,Micro g/L,N,28,PP,60,Pellet,N,1.612,0.078,3,3,2.478,0.261,3,3,3.309,0.367,3,3,5.176,0.485,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,4.175,0.318442,3,0.8,0.410262,1.951923,0.984167,9,2.306004,0.992052,2.287676,-0.33575,4.239599,Additive
16,466,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Malondialdehyde level,Malondialdehyde levels,nmol/mg,Stress response,Organic pollutants X Stress response,N,4,Micro g/L,Micro g/L,N,28,PE,60,Pellet,N,1.612,0.078,3,3,2.478,0.317,3,3,3.309,0.367,3,3,3.345,0.542,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,4.175,0.342913,3,0.8,0.453516,-1.46412,0.845303,9,2.306004,0.919404,2.120149,-3.58427,0.656032,Additive
16,467,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Malondialdehyde level,Malondialdehyde levels,nmol/mg,Stress response,Organic pollutants X Stress response,N,4,Micro g/L,Micro g/L,N,28,PVC,60,Pellet,N,1.612,0.078,3,3,1.964,0.55,3,3,3.309,0.367,3,3,2.971,0.402,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,3.661,0.467541,3,0.8,0.436004,-1.26604,0.800239,9,2.306004,0.894561,2.062861,-3.32891,0.796817,Additive
16,468,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,4,Micro g/L,Micro g/L,N,28,PP,60,Pellet,N,0.444,0.044,3,3,0.373,0.028,3,3,0.337,0.011,3,3,0.304,0.007,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.266,0.021272,3,0.8,0.015835,-1.91979,0.973799,9,2.306004,0.986812,2.275593,-4.19538,0.355806,Additive
16,469,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,4,Micro g/L,Micro g/L,N,28,PE,60,Pellet,N,0.444,0.044,3,3,0.377,0.036,3,3,0.337,0.011,3,3,0.377,0.048,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.27,0.026618,3,0.8,0.03881,-2.20559,1.072053,9,2.306004,1.0354,2.387637,-4.59323,0.182044,Additive
16,470,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,4,Micro g/L,Micro g/L,N,28,PVC,60,Pellet,N,0.444,0.044,3,3,0.426,0.039,3,3,0.337,0.011,3,3,0.366,0.033,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,0.319,0.028653,3,0.8,0.030903,-1.21671,0.790031,9,2.306004,0.888837,2.049662,-3.26637,0.832955,Additive
16,471,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,5-hydroxytryptamine level,5-hydroxytryptamine level,ng/ml,Biochemical,Organic pollutants X Biochemical,N,4,Micro g/L,Micro g/L,N,28,PP,60,Pellet,N,57.352,3,3,3,61.235,6.176,3,3,65.294,5.294,3,3,94.764,6.177,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,69.177,5.751931,3,0.8,5.968251,3.429749,1.646931,9,2.306004,1.283328,2.95936,0.470388,6.389109,Synergistic
16,472,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,5-hydroxytryptamine level,5-hydroxytryptamine level,ng/ml,Biochemical,Organic pollutants X Biochemical,N,4,Micro g/L,Micro g/L,N,28,PE,60,Pellet,N,57.352,3,3,3,63.882,5.647,3,3,65.294,5.294,3,3,55.588,6,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,71.824,5.473347,3,0.8,5.742714,-2.26179,1.092974,9,2.306004,1.045454,2.410821,-4.67261,0.149033,Additive
16,473,"The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish",Organic pollutants,Antibacterials,Triclosan,2,,5-hydroxytryptamine level,5-hydroxytryptamine level,ng/ml,Biochemical,Organic pollutants X Biochemical,N,4,Micro g/L,Micro g/L,N,28,PVC,60,Pellet,N,57.352,3,3,3,63.529,5.647,3,3,65.294,5.294,3,3,55.058,6.177,3,3,Y,Sheng,2021,Danio rerio,Danionidae,Adult,Benthopelagic,71.471,5.473347,3,0.8,5.835788,-2.24998,1.088534,9,2.306004,1.043328,2.405919,-4.6559,0.15594,Additive
17,474,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,ngnl relative expression,ngnl relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.9,0.564,3,3,1.014,1.507,3,3,1,0.878,3,3,1.035,0.322,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,1.114,1.233275,3,0.8,0.901291,-0.07012,0.667076,9,2.306004,0.816747,1.883423,-1.95354,1.813301,Additive
17,475,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,ngnl relative expression,ngnl relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.9,0.564,3,3,1.014,1.507,3,3,1.521,0.636,3,3,1.321,0.121,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,1.635,1.156621,3,0.8,0.822318,-0.30548,0.674443,9,2.306004,0.821245,1.893794,-2.19927,1.588316,Additive
17,476,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,neuro D relative expression,neuro D relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,2.508,1.259,3,3,0.366,0.151,3,3,0.366,0.366,3,3,0.553,0.607,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,-1.776,0.279962,3,0.8,0.472667,-3.94189,1.961542,9,2.306004,1.40055,3.229675,-7.17157,-0.71222,Antagonistic
17,477,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,neuro D relative expression,neuro D relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,2.508,1.259,3,3,0.366,0.151,3,3,1.616,0.634,3,3,1.196,0.518,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,-0.526,0.460845,3,0.8,0.490256,-2.80996,1.324656,9,2.306004,1.150937,2.654065,-5.46402,-0.15589,Antagonistic
17,478,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,olig 2 relative expression,olig 2 relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.305,2.651,3,3,0.427,0.125,3,3,0.263,0.289,3,3,0.791,1.106,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,-2.615,0.22265,3,0.8,0.79775,-3.41561,1.638865,9,2.306004,1.280182,2.952104,-6.36771,-0.4635,Antagonistic
17,479,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,olig 2 relative expression,olig 2 relative expression,Relative gene expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.305,2.651,3,3,0.427,0.125,3,3,2.475,0.767,3,3,2.978,1.709,3,3,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,-0.403,0.549506,3,0.8,1.269377,-2.13081,1.045029,9,2.306004,1.022266,2.357351,-4.48816,0.226542,Additive
17,480,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,Retina pcna immune cells,pcna immune cells,Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4,1.986,3,30,7.385,1.843,3,30,1.058,0.968,3,30,1.254,1.164,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,4.443,1.472018,30,0.987013,1.326976,-2.372,0.113553,90,1.986979,0.336976,0.669565,-3.04156,-1.70243,Antagonistic
17,481,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,Retina pcna immune cells,pcna immune cells,Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4,1.986,3,30,7.385,1.843,3,30,0.366,0.614,3,30,2.653,1.399,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,3.751,1.373617,30,0.987013,1.386366,0.781713,0.071759,90,1.986979,0.267879,0.532269,0.249444,1.313982,Synergistic
17,482,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,Brain pcna immune cells,pcna immune cells,Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.188,1.37,3,30,2.12,0.92,3,30,3.478,1.746,3,30,1.196,0.711,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,2.41,1.395514,30,0.987013,1.10747,1.081956,0.076422,90,1.986979,0.276445,0.549291,0.532666,1.631247,Synergistic
17,483,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,Brain pcna immune cells,pcna immune cells,Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.188,1.37,3,30,2.12,0.92,3,30,2.617,0.857,3,30,1.381,1.014,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,1.549,0.889058,30,0.987013,0.953578,0.173891,0.066919,90,1.986979,0.258686,0.514004,-0.34011,0.687895,Additive
17,484,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,"Retina islet 1,2 immune cells","Islet 1,2 immune cells",Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,5.192,2.855,3,30,5.192,2.745,3,30,7.654,2.087,3,30,3.294,1.741,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,7.654,2.438298,30,0.987013,2.118535,-2.0313,0.101051,90,1.986979,0.317886,0.631633,-2.66293,-1.39967,Antagonistic
17,485,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,"Retina islet 1,2 immune cells","Islet 1,2 immune cells",Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,5.192,2.855,3,30,5.192,2.745,3,30,5.96,2.745,3,30,5.568,2.839,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,5.96,2.745,30,0.987013,2.792396,-0.13856,0.066827,90,1.986979,0.258509,0.513651,-0.65221,0.375093,Additive
17,486,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,"Brain islet 1,2 immune cells","Islet 1,2 immune cells",Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,1.772,0.824,3,30,2.454,1.216,3,30,2,0.847,3,30,1.474,0.549,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,2.682,1.04787,30,0.987013,0.836491,-1.42537,0.083597,90,1.986979,0.289132,0.574499,-1.99987,-0.85087,Antagonistic
17,487,Microplastics- and copper-induced changes in neurogenesis and DNA methyltransferases in the early life stages of zebrafish,Inorganic pollutants,Metal contaminants,Copper,3,,"Brain islet 1,2 immune cells","Islet 1,2 immune cells",Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,1.772,0.824,3,30,2.454,1.216,3,30,1.772,0.996,3,30,2.47,0.808,3,30,Y,Santos,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,2.454,1.111457,30,0.987013,0.971648,0.016253,0.066669,90,1.986979,0.258203,0.513044,-0.49679,0.529297,Additive
18,488,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Body weight,Body mass/body mass growth,g,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.53,0.17,3,15,0.49,0.14,3,15,0.47,0.14,3,15,0.47,0.14,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.43,0.14,15,0.972973,0.14,-0.27799,0.134621,45,2.015368,0.366908,0.739454,-1.01745,0.461462,Additive
18,489,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Total length,Body length/body length growth,cm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,3.59,0.3,3,15,3.52,0.3,3,15,3.47,0.29,3,15,3.49,0.33,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,3.4,0.295042,15,0.972973,0.31301,-0.27976,0.134638,45,2.015368,0.36693,0.739499,-1.01926,0.459739,Additive
18,490,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Condition factor,Condition factor,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,1.12,0.25,3,15,1.13,0.31,3,15,1.09,0.19,3,15,1.08,0.15,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,1.1,0.257099,15,0.972973,0.210476,0.092455,0.133476,45,2.015368,0.365343,0.736301,-0.64385,0.828756,Additive
18,491,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Reactive oxygen species,Reactive oxygen species,Micro mol DCF/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,664.697,163.073,3,15,785.229,184.343,3,15,682.422,88.627,3,15,847.2,195.05,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,802.954,144.6324,15,0.972973,171.7018,0.250726,0.134381,45,2.015368,0.36658,0.738794,-0.48807,0.98952,Additive
18,492,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,643.427,168.39,3,15,767.504,184.342,3,15,682.422,85.082,3,15,748.006,196.75,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,806.499,143.5634,15,0.972973,172.2223,-0.33046,0.135153,45,2.015368,0.367632,0.740914,-1.07137,0.410457,Additive
18,493,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,113.991,43.299,3,15,88.07,30.929,3,15,116.348,26.215,3,15,72.164,25.626,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,90.427,28.66905,15,0.972973,27.19013,0.653524,0.140452,45,2.015368,0.374769,0.755297,-0.10177,1.408821,Additive
18,494,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Glutathione peroxidase activity,Glutathione peroxidase activity/expression,Micro mol NADPH/min.mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,120.471,33.874,3,15,90.427,36.23,3,15,67.452,26.804,3,15,80.117,32.991,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,37.408,31.86744,15,0.972973,32.43409,-1.2812,0.160691,45,2.015368,0.400863,0.807887,-2.08909,-0.47332,Antagonistic
18,495,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Glutathione S-transferase activity,Glutathione S-transferase activity,nmol CDNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,269.359,100.297,3,15,310.292,61.209,3,15,316.557,84.804,3,15,364.867,84.799,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,357.49,73.95357,15,0.972973,79.5613,0.090215,0.133469,45,2.015368,0.365334,0.736282,-0.64607,0.826497,Additive
18,496,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Lipid peroxidase activity,Lipid peroxidase activity,Micro mol MDA/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,398.23,119.469,3,15,508.85,178.466,3,15,449.853,132.743,3,15,616.519,258.112,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,560.473,157.2749,15,0.972973,213.7255,0.255146,0.134418,45,2.015368,0.366631,0.738896,-0.48375,0.994042,Additive
18,497,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Reduced glutathione,Reduced glutathione level,Micro mol/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,722.078,324.672,3,15,688.312,285.714,3,15,1145.45,420.78,3,15,729.87,324.68,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,1111.684,359.6445,15,0.972973,342.6086,-1.08431,0.152929,45,2.015368,0.391061,0.788132,-1.87244,-0.29618,Antagonistic
18,498,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Oxidised glutathione,Oxidised glutathione,Micro mol/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,496.104,229.87,3,15,444.156,268.831,3,15,641.558,218.182,3,15,461.039,210.39,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,589.61,244.8198,15,0.972973,228.255,-0.54805,0.138339,45,2.015368,0.37194,0.749596,-1.29765,0.201542,Additive
18,499,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Glutathione reductase activity,Glutathione reductase activity,Micro mol NADPH/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,51.428,29.091,3,15,64.415,19.221,3,15,65.454,34.546,3,15,61.818,22.597,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,78.441,27.95419,15,0.972973,25.41713,-0.63633,0.140082,45,2.015368,0.374275,0.754302,-1.39063,0.11797,Additive
18,500,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Metallothionein,Metallothionein level,Micro mol GSH/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,2.4,1.085,3,15,4.742,1.772,3,15,5.542,1.715,3,15,3.6,1.542,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,7.884,1.743733,15,0.972973,1.64596,-2.53239,0.240217,45,2.015368,0.490119,0.98777,-3.52016,-1.54462,Antagonistic
18,501,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.0765,0.0455,3,15,0.096,0.05,3,15,0.0994,0.0686,3,15,0.0777,0.0583,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.1189,0.060025,15,0.972973,0.059169,-0.67749,0.140983,45,2.015368,0.375477,0.756725,-1.43422,0.07923,Additive
18,502,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Lactate dehydrogenase,Lactate dehydrogenase activity/level,Micro mol NADH/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,733.714,240,3,15,445.714,198.857,3,15,582.857,288,3,15,390.857,233.143,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,294.857,247.4754,15,0.972973,240.416,-0.38852,0.135849,45,2.015368,0.368577,0.742818,-1.13133,0.354303,Additive
18,503,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.281,0.123,3,18,0.291,0.161,3,18,0.24,0.102,3,18,0.372,0.189,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.25,0.134768,18,0.97561,0.161531,-0.73685,0.130449,51,2.008559,0.361177,0.725445,-1.4623,-0.01141,Antagonistic
18,504,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Catalase activity,Catalase activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.054,0.028,3,18,0.075,0.054,3,18,0.057,0.026,3,18,0.107,0.085,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.078,0.042379,18,0.97561,0.065175,0.434102,0.125077,51,2.008559,0.353663,0.710353,-0.27625,1.144455,Additive
18,505,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,gclc activity,gclc activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.386,0.185,3,18,0.35,0.267,3,18,0.273,0.145,3,18,0.379,0.198,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.237,0.214842,18,0.97561,0.207405,-0.66795,0.128982,51,2.008559,0.359141,0.721356,-1.38931,0.053405,Additive
18,506,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,gstp1 activity,gstp1 activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.263,0.143,3,18,0.266,0.178,3,18,0.223,0.096,3,18,0.391,0.194,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.226,0.143003,18,0.97561,0.167963,-0.9584,0.136139,51,2.008559,0.368971,0.7411,-1.6995,-0.2173,Antagonistic
18,507,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,mt2 activity,mt2 activity,Relative expression,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.177,0.107,3,18,0.16,0.099,3,18,0.157,0.101,3,18,0.235,0.148,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.14,0.100005,18,0.97561,0.124002,-0.74743,0.130687,51,2.008559,0.361506,0.726106,-1.47354,-0.02132,Antagonistic
18,508,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,tph1a activity,tph1a activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.148,0.103,3,18,0.503,0.348,3,18,0.153,0.085,3,18,0.335,0.238,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.508,0.253307,18,0.97561,0.246512,-0.68467,0.129325,51,2.008559,0.359618,0.722314,-1.40699,0.037639,Additive
18,509,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,tph1b activity,tph1b activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.173,0.144,3,18,0.224,0.178,3,18,0.133,0.126,3,18,0.296,0.199,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.184,0.154208,18,0.97561,0.175855,0.621355,0.128072,51,2.008559,0.357871,0.718806,-0.09745,1.34016,Additive
18,510,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,tph2 activity,tph2 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.208,0.096,3,18,0.274,0.228,3,18,0.261,0.181,3,18,0.267,0.133,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.327,0.205846,18,0.97561,0.176706,-0.33126,0.123885,51,2.008559,0.351973,0.706958,-1.03822,0.375693,Additive
18,511,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,slc6a4a activity,slc6a4a activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.244,0.121,3,18,0.264,0.176,3,18,0.202,0.109,3,18,0.255,0.116,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.222,0.146385,18,0.97561,0.133522,-0.24112,0.123103,51,2.008559,0.350861,0.704724,-0.94585,0.463601,Additive
18,512,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,slc6a4b activity,slc6a4b activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.152,0.226,3,18,0.058,0.024,3,18,0.147,0.141,3,18,0.178,0.195,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.053,0.101136,18,0.97561,0.150936,-0.80796,0.132113,51,2.008559,0.363474,0.730059,-1.53802,-0.07791,Antagonistic
18,513,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.103,0.061,3,18,0.174,0.116,3,18,0.088,0.052,3,18,0.213,0.141,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.159,0.089889,18,0.97561,0.115799,0.45495,0.125358,51,2.008559,0.35406,0.71115,-0.2562,1.1661,Additive
18,514,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Caspase 3 activity,Caspase 3 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.115,0.067,3,18,0.195,0.15,3,18,0.15,0.11,3,18,0.24,0.144,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.23,0.131529,18,0.97561,0.137302,0.071056,0.122299,51,2.008559,0.349712,0.702418,-0.63136,0.773474,Additive
18,515,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Caspase 8 activity,Caspase 8 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.339,0.105,3,18,0.35,0.226,3,18,0.288,0.138,3,18,0.445,0.222,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.299,0.187243,18,0.97561,0.203676,-0.69934,0.129633,51,2.008559,0.360045,0.723172,-1.42251,0.023829,Additive
18,516,"Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper",Inorganic pollutants,Metal contaminants,Copper,2,,Caspase 9 activity,Caspase 9 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,30,Undisclosed,5,Spheres,Y,0.266,0.133,3,18,0.25,0.172,3,18,0.167,0.086,3,18,0.251,0.11,3,15,N,Santos,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.151,0.135978,18,0.97561,0.124917,-0.78101,0.131464,51,2.008559,0.36258,0.728263,-1.50927,-0.05274,Antagonistic
19,522,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Cumulative mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,Y,14,Undisclosed,5,Spheres,Y,14.428,4.439,5,500,32.297,3.774,5,500,37.735,9.545,5,500,36.071,6.215,5,500,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,55.604,7.257758,500,0.999248,6.756526,-2.88881,0.008173,1500,1.961548,0.090402,0.177329,-3.06614,-2.71148,Antagonistic
19,523,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Cumulative mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,Y,14,Undisclosed,5,Spheres,Y,14.428,4.439,5,500,32.297,3.774,5,500,48.834,10.544,5,500,60.044,8.546,5,500,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,66.703,7.918933,500,0.999248,8.238435,-0.80768,0.004326,1500,1.961548,0.065774,0.129018,-0.9367,-0.67866,Antagonistic
19,524,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Speed,Swimming speed,cm/min,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,162.234,38.564,5,30,138.298,18.085,5,30,107.181,37.766,5,30,95.744,37.235,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,83.245,29.6086,30,0.987013,33.63863,-0.36674,0.067787,90,1.986979,0.26036,0.51733,-0.88407,0.150589,Additive
19,525,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Speed,Swimming speed,cm/min,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,162.234,38.564,5,30,138.298,18.085,5,30,85.904,29.787,5,30,67.287,24.468,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,61.968,24.64074,30,0.987013,24.55452,-0.21381,0.067048,90,1.986979,0.258936,0.514499,-0.72831,0.300693,Additive
19,526,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Distance moved,Total distance moved,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,180.064,43.177,5,30,146.482,36.78,5,30,128.891,39.979,5,30,108.742,38.38,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,95.309,38.41282,30,0.987013,38.39641,-0.34531,0.06766,90,1.986979,0.260116,0.516845,-0.86215,0.171538,Additive
19,527,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Distance moved,Total distance moved,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,180.064,43.177,5,30,146.482,36.78,5,30,97.548,32.942,5,30,84.754,34.542,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,63.966,34.91378,30,0.987013,34.72839,-0.59081,0.069576,90,1.986979,0.263772,0.524109,-1.11492,-0.06671,Antagonistic
19,528,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Distance to cover,Distance to cover,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,1.08,0.128,5,30,1.148,0.128,5,30,1.234,0.148,5,30,1.17,0.176,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,1.302,0.138362,30,0.987013,0.158304,-0.82301,0.072311,90,1.986979,0.268907,0.534313,-1.35733,-0.2887,Antagonistic
19,529,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Distance to cover,Distance to cover,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,1.08,0.128,5,30,1.148,0.128,5,30,1.229,0.1,5,30,1.272,0.132,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,1.297,0.114856,30,0.987013,0.123726,-0.19944,0.066998,90,1.986979,0.25884,0.514309,-0.71375,0.314873,Additive
19,530,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Time active,Time active,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,30.851,7.18,5,30,30.957,7.074,5,30,27.393,6.755,5,30,24.042,6.011,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,27.499,6.916339,30,0.987013,6.479501,0.5266,0.068978,90,1.986979,0.262636,0.521852,0.004748,1.048452,Synergistic
19,531,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Time active,Time active,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,30.851,7.18,5,30,30.957,7.074,5,30,33.776,1.702,5,30,21.648,5.586,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,33.882,5.144817,30,0.987013,5.369941,-2.24865,0.108804,90,1.986979,0.329854,0.655413,-2.90406,-1.59324,Antagonistic
19,532,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Absolute turn angle,Absolute turn angle,Degrees,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,9.784,1.755,5,30,8.465,1.404,5,30,7.034,2.553,5,30,5.571,2.187,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,5.715,2.060221,30,0.987013,2.124557,0.066899,0.066704,90,1.986979,0.258271,0.513179,-0.44628,0.580078,Additive
19,533,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Absolute turn angle,Absolute turn angle,Degrees,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,9.784,1.755,5,30,8.465,1.404,5,30,5.529,2.202,5,30,4.098,1.675,5,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,4.21,1.846621,30,0.987013,1.7629,0.062707,0.066699,90,1.986979,0.258262,0.513162,-0.45046,0.575868,Additive
19,534,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Nearest neighbour distance,Nearest neighbour distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.995,0.073,5,25,0.959,0.078,5,25,0.99,0.075,5,25,0.916,0.098,5,25,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,0.954,0.076515,25,0.984293,0.087916,0.425441,0.08181,75,1.992543,0.286024,0.569916,-0.14448,0.995357,Additive
19,535,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Nearest neighbour distance,Nearest neighbour distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.995,0.073,5,25,0.959,0.078,5,25,0.967,0.109,5,25,0.948,0.133,5,25,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,0.931,0.094776,25,0.984293,0.115481,-0.1449,0.08021,75,1.992543,0.283214,0.564315,-0.70921,0.419417,Additive
19,536,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Inter-individual distance,Inter-individual distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.317,0.314,5,25,3.171,0.303,5,25,3.119,0.287,5,25,2.988,0.277,5,25,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,2.973,0.295108,25,0.984293,0.286197,-0.05159,0.080027,75,1.992543,0.28289,0.56367,-0.61526,0.512082,Additive
19,537,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Inter-individual distance,Inter-individual distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,3.317,0.314,5,25,3.171,0.303,5,25,3.093,0.287,5,25,3.04,0.366,5,25,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,2.947,0.295108,25,0.984293,0.332449,-0.27535,0.080758,75,1.992543,0.28418,0.566241,-0.84159,0.290893,Additive
19,538,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.236,0.008,5,150,0.0646,0.0116,5,150,0.155,0.019,5,150,0.0879,0.0116,5,150,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.0164,0.015741,150,0.997481,0.013826,-7.52453,0.107697,450,1.965261,0.328173,0.644946,-8.16947,-6.87958,Antagonistic
19,539,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,0.236,0.008,5,150,0.0646,0.0116,5,150,0.164,0.015,5,150,0.0519,0.0084,5,150,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.0074,0.013408,150,0.997481,0.011188,-5.287,0.059921,450,1.965261,0.244787,0.48107,-5.76807,-4.80593,Antagonistic
19,540,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,72 hpf,Hatching rate,Hatching rate,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,72.7,7.3,5,500,66.6,9.7,5,500,32.9,21,5,500,36.5,10.7,5,500,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,26.8,16.3568,500,0.999248,13.82091,-0.70131,0.004246,1500,1.961548,0.065161,0.127816,-0.82912,-0.57349,Antagonistic
19,541,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,72 hpf,Hatching rate,Hatching rate,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,72.7,7.3,5,500,66.6,9.7,5,500,21.5,8.8,5,500,16.5,6.8,5,500,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,15.4,9.260939,500,0.999248,8.124192,-0.1353,0.004009,1500,1.961548,0.063318,0.124201,-0.2595,-0.0111,Antagonistic
19,542,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4.3,0.2,5,75,4,0.3,5,75,4,0.3,5,75,4,0.2,5,75,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,3.7,0.3,75,0.994924,0.254951,-1.17072,0.031235,225,1.970611,0.176735,0.348276,-1.519,-0.82245,Antagonistic
19,543,Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4.3,0.2,5,75,4,0.3,5,75,3.9,0.3,5,75,3.7,0.3,5,75,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,3.6,0.3,75,0.994924,0.3,-0.33164,0.027033,225,1.970611,0.164418,0.324004,-0.65565,-0.00764,Antagonistic
20,550,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Cumulative mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,Y,14,Undisclosed,5,Spheres,Y,14.602,4.33,3,1950,32.225,3.827,3,1950,37.764,9.567,3,1950,36.052,6.244,3,1950,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,55.387,7.286063,1950,0.999808,6.785066,-2.84909,0.002066,5850,1.96037,0.045457,0.089112,-2.9382,-2.75998,Antagonistic
20,551,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Cumulative mortality,Mortality,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,Y,14,Undisclosed,5,Spheres,Y,14.602,4.33,3,1950,32.225,3.827,3,1950,48.841,10.373,3,1950,59.919,8.56,3,1950,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,66.464,7.81809,1950,0.999808,8.197443,-0.79827,0.001107,5850,1.96037,0.033277,0.065235,-0.8635,-0.73303,Antagonistic
20,552,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,2 dpf,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,117,8.7,3,30,125,6.5,3,30,125,11.5,3,30,129,10.8,3,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,133,9.340771,30,0.987013,10.09678,-0.39102,0.067941,90,1.986979,0.260655,0.517915,-0.90894,0.126894,Additive
20,553,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,2 dpf,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,117,8.7,3,30,125,6.5,3,30,130,12.8,3,30,134,11,3,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,138,10.15111,30,0.987013,10.58407,-0.37302,0.067826,90,1.986979,0.260435,0.517478,-0.8905,0.14446,Additive
20,554,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,2 dpf,Hatching rate,Hatching rate,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,73,7.3,3,30,67,9.7,3,30,32,21,3,30,37,10.7,3,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,26,16.3568,30,0.987013,13.82091,-0.78556,0.071809,90,1.986979,0.267972,0.532455,-1.31801,-0.2531,Antagonistic
20,555,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,2 dpf,Hatching rate,Hatching rate,Percent,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,73,7.3,3,30,67,9.7,3,30,21,8.8,3,30,16,6.8,3,30,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,15,9.260939,30,0.987013,8.124192,-0.12149,0.06679,90,1.986979,0.258437,0.513509,-0.635,0.392018,Additive
20,556,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4.25,0.19,3,45,4.06,0.25,3,45,3.96,0.28,3,45,3.95,0.25,3,45,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,3.77,0.265424,45,0.991453,0.257827,-0.69217,0.047106,135,1.977826,0.217039,0.429266,-1.12144,-0.26291,Antagonistic
20,557,Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages,Inorganic pollutants,Metal contaminants,Copper,3,14 dpf,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,14,Undisclosed,5,Spheres,Y,4.25,0.19,3,45,4.06,0.25,3,45,3.91,0.28,3,45,3.76,0.31,3,45,Y,Santos,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,3.72,0.265424,45,0.991453,0.288574,-0.13743,0.044549,135,1.977826,0.211067,0.417454,-0.55488,0.280026,Additive
21,558,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.38,0.21,5,75,3.27,0.26,5,75,3.22,0.36,5,75,3.23,0.29,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.11,0.314006,75,0.994924,0.302242,-0.39502,0.027187,225,1.970611,0.164884,0.324923,-0.71994,-0.0701,Antagonistic
21,559,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.38,0.21,5,75,3.27,0.26,5,75,3.18,0.18,5,75,3.07,0.32,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.07,0.223607,75,0.994924,0.276043,1.60E-15,0.026667,225,1.970611,0.163299,0.321799,-0.3218,0.321799,Additive
21,560,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Body length,Body length/body length growth,mm,Ecological,Inorganic pollutants X Ecological,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.38,0.21,5,75,3.27,0.26,5,75,2.91,0.33,5,75,2.96,0.23,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.8,0.297069,75,0.994924,0.26566,-0.59922,0.027864,225,1.970611,0.166924,0.328942,-0.92816,-0.27028,Antagonistic
21,561,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Eye diameter,Eye diameter,mm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.35,0.02,5,75,0.35,0.03,5,75,0.34,0.03,5,75,0.33,0.03,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.34,0.03,75,0.994924,0.03,0.331641,0.027033,225,1.970611,0.164418,0.324004,0.007637,0.655645,Synergistic
21,562,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Eye diameter,Eye diameter,mm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.35,0.02,5,75,0.35,0.03,5,75,0.32,0.02,5,75,0.31,0.03,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.32,0.025495,75,0.994924,0.027839,0.357387,0.027092,225,1.970611,0.164598,0.324358,0.033029,0.681745,Synergistic
21,563,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Eye diameter,Eye diameter,mm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.35,0.02,5,75,0.35,0.03,5,75,0.3,0.02,5,75,0.3,0.02,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.3,0.025495,75,0.994924,0.022913,-2.41E-15,0.026667,225,1.970611,0.163299,0.321799,-0.3218,0.321799,Additive
21,567,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,96 hpf,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,Y,4,Undisclosed,5,Spheres,Y,157,9.3,5,50,155,9.7,5,50,145,8.8,5,50,147,8.8,5,50,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,143,9.260939,50,0.992327,9.03341,-0.4394,0.040965,150,1.976013,0.202399,0.399943,-0.83935,-0.03946,Antagonistic
21,568,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,96 hpf,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,Y,4,Undisclosed,5,Spheres,Y,157,9.3,5,50,155,9.7,5,50,144,12.5,5,50,149,9.4,5,50,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,142,11.18794,50,0.992327,10.33272,-0.67226,0.04226,150,1.976013,0.205572,0.406212,-1.07847,-0.26605,Antagonistic
21,569,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,96 hpf,Heart rate,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,Y,4,Undisclosed,5,Spheres,Y,157,9.3,5,50,155,9.7,5,50,158,8.8,5,50,159,10.9,5,50,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,156,9.260939,50,0.992327,10.11373,-0.29435,0.040433,150,1.976013,0.20108,0.397337,-0.69169,0.102986,Additive
21,570,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Morphological abnormalities,Morphological abnormalities,Percent,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0,0,5,75,0.21,0.5,5,75,2.48,0.6,5,75,2.11,1.9,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.69,0.552268,75,0.994924,1.399107,-0.41245,0.027234,225,1.970611,0.165026,0.325203,-0.73765,-0.08724,Antagonistic
21,571,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Morphological abnormalities,Morphological abnormalities,Percent,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0,0,5,75,0.21,0.5,5,75,2.73,1.6,5,75,2.29,1.1,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.94,1.185327,75,0.994924,1.14346,-0.56556,0.027733,225,1.970611,0.166532,0.32817,-0.89373,-0.2374,Antagonistic
21,572,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Morphological abnormalities,Morphological abnormalities,Percent,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0,0,5,75,0.21,0.5,5,75,1.79,1.3,5,75,2.23,1.8,5,75,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2,0.984886,75,0.994924,1.450862,0.157722,0.02675,225,1.970611,0.163553,0.322299,-0.16458,0.480021,Additive
21,573,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reactive oxygen species levels,Reactive oxygen species,Micro mol DCF/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,62.9,14.4,5,5,94.2,15.4,5,5,99.3,10.2,5,5,131.2,24.5,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,130.6,13.06139,5,0.903226,19.63224,0.027604,0.400038,15,2.144787,0.632486,1.356547,-1.32894,1.384151,Additive
21,574,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reactive oxygen species levels,Reactive oxygen species,Micro mol DCF/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,62.9,14.4,5,5,94.2,15.4,5,5,99.3,14.3,5,5,103.7,18.9,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,130.6,14.86018,5,0.903226,17.00051,-1.42918,0.502128,15,2.144787,0.70861,1.519816,-2.949,0.090638,Additive
21,575,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reactive oxygen species levels,Reactive oxygen species,Micro mol DCF/mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,62.9,14.4,5,5,94.2,15.4,5,5,55.4,13.4,5,5,61.4,11.3,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,86.7,14.43468,5,0.903226,12.96245,-1.76291,0.555392,15,2.144787,0.745247,1.598395,-3.3613,-0.16451,Antagonistic
21,576,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactoperoxidase level,Lactoperoxidase level,Micro mol MDA/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,2.2,0.2,5,5,1.7,0.4,5,5,1.7,0.4,5,5,2.4,0.3,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.2,0.4,5,0.903226,0.353553,-3.06565,0.869911,15,2.144787,0.93269,2.000421,-5.06607,-1.06523,Antagonistic
21,577,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactoperoxidase level,Lactoperoxidase level,Micro mol MDA/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,2.2,0.2,5,5,1.7,0.4,5,5,1.6,0.2,5,5,0.9,0.4,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.1,0.316228,5,0.903226,0.360555,0.50102,0.412551,15,2.144787,0.642301,1.377599,-0.87658,1.878619,Additive
21,578,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactoperoxidase level,Lactoperoxidase level,Micro mol MDA/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,2.2,0.2,5,5,1.7,0.4,5,5,1,0.2,5,5,1.2,0.2,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.5,0.316228,5,0.903226,0.264575,-2.38971,0.685536,15,2.144787,0.827971,1.775821,-4.16553,-0.61389,Antagonistic
21,579,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,412.9,62.9,5,5,423,47.9,5,5,391.5,54.9,5,5,474.1,50.9,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,401.6,51.51903,5,0.903226,51.21045,-1.27872,0.481756,15,2.144787,0.694087,1.488668,-2.76739,0.209947,Additive
21,580,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,412.9,62.9,5,5,423,47.9,5,5,452.3,54.7,5,5,433.3,86.3,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,462.4,51.41255,5,0.903226,71.03147,-0.37003,0.406846,15,2.144787,0.637845,1.368041,-1.73807,0.99801,Additive
21,581,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,412.9,62.9,5,5,423,47.9,5,5,238.7,72.4,5,5,226.9,43.4,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,248.8,61.38473,5,0.903226,53.15847,0.372107,0.406923,15,2.144787,0.637905,1.368171,-0.99606,1.740278,Additive
21,582,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase acivity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,8.1,1.6,5,5,8.9,2.2,5,5,17.4,4.6,5,5,11.4,4.2,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,18.2,3.605551,5,0.903226,3.914077,-1.56919,0.523118,15,2.144787,0.723269,1.551258,-3.12045,-0.01793,Antagonistic
21,583,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase acivity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,8.1,1.6,5,5,8.9,2.2,5,5,18.2,4.2,5,5,30.2,11.8,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,19,3.352611,5,0.903226,8.674099,1.166245,0.468006,15,2.144787,0.68411,1.46727,-0.30102,2.633515,Additive
21,584,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase acivity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,8.1,1.6,5,5,8.9,2.2,5,5,43,13.1,5,5,58.8,17.6,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,43.8,9.392816,5,0.903226,14.10647,0.960438,0.446122,15,2.144787,0.667924,1.432554,-0.47212,2.392992,Additive
21,585,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione peroxidase acivity,Glutathione peroxidase activity/expression,Micro mol NADPH/min.mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,14.8,2.8,5,5,15.1,5.2,5,5,11.6,4.4,5,5,12.2,5.2,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,11.9,4.816638,5,0.903226,5.011986,-0.05406,0.400146,15,2.144787,0.632571,1.35673,-1.41079,1.302666,Additive
21,586,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione peroxidase acivity,Glutathione peroxidase activity/expression,Micro mol NADPH/min.mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,14.8,2.8,5,5,15.1,5.2,5,5,11.1,1.6,5,5,11.1,2.3,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,11.4,3.847077,5,0.903226,3.169385,0.085495,0.400365,15,2.144787,0.632744,1.357102,-1.27161,1.442597,Additive
21,587,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione peroxidase acivity,Glutathione peroxidase activity/expression,Micro mol NADPH/min.mgProtein,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,14.8,2.8,5,5,15.1,5.2,5,5,30.9,8.8,5,5,44.2,6.8,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,31.2,7.227724,5,0.903226,7.017122,1.673326,0.540001,15,2.144787,0.734848,1.576091,0.097235,3.249418,Synergistic
21,588,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione S-transferase acivity,Glutathione S-transferase activity,Micro mol CDNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.05,0.01,5,5,0.06,0.01,5,5,0.05,0.01,5,5,0.07,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.06,0.01,5,0.903226,0.01,0.903226,0.440791,15,2.144787,0.663921,1.423969,-0.52074,2.327194,Additive
21,589,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione S-transferase acivity,Glutathione S-transferase activity,Micro mol CDNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.05,0.01,5,5,0.06,0.01,5,5,0.04,0.02,5,5,0.05,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.05,0.015811,5,0.903226,0.013229,0,0.4,15,2.144787,0.632456,1.356482,-1.35648,1.356482,Additive
21,590,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione S-transferase acivity,Glutathione S-transferase activity,Micro mol CDNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.05,0.01,5,5,0.06,0.01,5,5,0.07,0.02,5,5,0.08,0.02,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.08,0.015811,5,0.903226,0.018028,0,0.4,15,2.144787,0.632456,1.356482,-1.35648,1.356482,Additive
21,591,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione level,Glutathione level,Micro mol/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1815,192.7,5,5,1888,183.7,5,5,1658,196.3,5,5,2091,196.4,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1731,190.1044,5,0.903226,193.2778,-1.68235,0.541515,15,2.144787,0.735877,1.5783,-3.26065,-0.10405,Antagonistic
21,592,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione level,Glutathione level,Micro mol/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1815,192.7,5,5,1888,183.7,5,5,1640,151.1,5,5,2390,225.1,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1713,168.1917,5,0.903226,1.99E+02,-3.07752,0.873556,15,2.144787,0.934642,2.004608,-5.08213,-1.07291,Antagonistic
21,593,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione level,Glutathione level,Micro mol/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1815,192.7,5,5,1888,183.7,5,5,1157,98.3,5,5,1536,181.3,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1230,147.3238,5,0.903226,165.1877,-1.67317,0.539975,15,2.144787,0.73483,1.576053,-3.24922,-0.09712,Antagonistic
21,594,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reduced glutathione level,Reduced glutathione level,Micro mol/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,5670,4833,5,5,5769,597.4,5,5,5751,266.1,5,5,7217,276.6,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,5850,462.437,5,0.903226,381.022,3.240521,0.925049,15,2.144787,0.961795,2.062844,1.177677,5.303365,Synergistic
21,595,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reduced glutathione level,Reduced glutathione level,Micro mol/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,5670,4833,5,5,5769,597.4,5,5,5229,482.3,5,5,2993,378,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,5328,542.9089,5,0.903226,467.7788,4.50861,1.416378,15,2.144787,1.190117,2.552547,1.956063,7.061157,Synergistic
21,596,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Reduced glutathione level,Reduced glutathione level,Micro mol/mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,5670,4833,5,5,5769,597.4,5,5,3066,349.2,5,5,2965,325.7,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3165,489.2992,5,0.903226,415.6286,0.434631,0.409445,15,2.144787,0.639879,1.372404,-0.93777,1.807035,Additive
21,597,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione to reduced glutathione ratio,Glutathione to reduced glutathione ratio,Ratio,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.34,0.01,5,5,0.34,0.02,5,5,0.3,0.05,5,5,0.3,0.02,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.3,0.038079,5,0.903226,0.030414,0,0.4,15,2.144787,0.632456,1.356482,-1.35648,1.356482,Additive
21,598,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione to reduced glutathione ratio,Glutathione to reduced glutathione ratio,Ratio,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.34,0.01,5,5,0.34,0.02,5,5,0.31,0.02,5,5,0.7,0.09,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.31,0.02,5,0.903226,0.065192,-5.40339,1.859832,15,2.144787,1.363757,2.924967,-8.32836,-2.47842,Antagonistic
21,599,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Glutathione to reduced glutathione ratio,Glutathione to reduced glutathione ratio,Ratio,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.34,0.01,5,5,0.34,0.02,5,5,0.38,0.05,5,5,0.52,0.1,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.38,0.038079,5,0.903226,0.075664,1.671232,0.539651,15,2.144787,0.734609,1.57558,0.095651,3.246812,Synergistic
21,600,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.09,0.01,5,5,0.07,0.01,5,5,0.06,0.01,5,5,0.06,0.004,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.04,0.01,5,0.903226,0.007616,-2.37199,0.681316,15,2.144787,0.825419,1.770347,-4.14233,-0.60164,Antagonistic
21,601,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.09,0.01,5,5,0.07,0.01,5,5,0.03,0.01,5,5,0.03,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.01,0.01,5.00E+00,0.903226,0.01,-1.80645,0.563163,15,2.144787,0.750442,1.609538,-3.41599,-0.19691,Antagonistic
21,602,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,Micro mol TNB/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.09,0.01,5,5,0.07,0.01,5,5,0.05,0.01,5,5,0.06,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.03,0.01,5,0.903226,0.01,-2.70968,0.767118,15,2.144787,0.875852,1.878517,-4.58819,-0.83116,Antagonistic
21,603,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,Micro mol NADH/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.41,0.05,5,5,0.38,0.06,5,5,0.32,0.03,5,5,0.47,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.29,0.047434,5,0.903226,0.034278,-4.74296,1.524786,15,2.144787,1.234822,2.64843,-7.3914,-2.09453,Antagonistic
21,604,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,Micro mol NADH/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.41,0.05,5,5,0.38,0.06,5,5,0.35,0.07,5,5,0.42,0.07,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.32,0.065192,5,0.903226,0.067639,-1.33537,0.48916,15,2.144787,0.6994,1.500064,-2.83543,0.164696,Additive
21,605,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,Micro mol NADH/min.mgProtein,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.41,0.05,5,5,0.38,0.06,5,5,0.06,0.01,5,5,0.06,0.01,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.03,0.043012,5,0.903226,0.031225,-0.86779,0.437653,15,2.144787,0.661554,1.418891,-2.28668,0.5511,Additive
21,606,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallotheonein level,Metallothionein level,Micro mol GSH/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,4.5,0.6,5,5,3.5,0.7,5,5,3.6,0.9,5,5,4.7,0.8,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.6,0.806226,5,0.903226,0.803119,-2.36176,0.678896,15,2.144787,0.823951,1.7672,-4.12896,-0.59456,Antagonistic
21,607,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallotheonein level,Metallothionein level,Micro mol GSH/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,4.5,0.6,5,5,3.5,0.7,5,5,3.2,0.6,5,5,2.9,0.4,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.2,0.65192,5,0.903226,0.540833,-1.16905,0.468333,15,2.144787,0.684349,1.467782,-2.63683,0.298737,Additive
21,608,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallotheonein level,Metallothionein level,Micro mol GSH/mgProtein,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,4.5,0.6,5,5,3.5,0.7,5,5,2.4,0.3,5,5,3.5,0.5,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.4,0.538516,5,0.903226,5.20E-01,-3.65034,1.06625,15,2.144787,1.032594,2.214694,-5.86504,-1.43565,Antagonistic
21,609,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase expression,Catalase activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.703,0.068,5,5,0.74,0.123,5,5,0.388,0.188,5,5,0.811,0.113,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.425,0.15886,5,0.903226,0.13785,-2.52915,0.719831,15,2.144787,0.848429,1.819699,-4.34885,-0.70946,Antagonistic
21,610,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase expression,Catalase activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.703,0.068,5,5,0.74,0.123,5,5,0.541,0.138,5,5,0.511,0.203,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.578,0.130715,5,0.903226,0.170727,0.354461,0.406282,15,2.144787,0.637403,1.367093,-1.01263,1.721554,Additive
21,611,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Catalase expression,Catalase activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,0.703,0.068,5,5,0.74,0.123,5,5,0.465,0.147,5,5,0.673,0.347,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.502,0.135532,5,0.903226,0.263418,-0.58634,0.41719,15,2.144787,0.645902,1.385322,-1.97166,0.798985,Additive
21,612,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase expression,Superoxide dismutase activity/expression,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.101,0.046,5,5,0.526,0.142,5,5,0.423,0.046,5,5,0.78,0.214,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.152,0.105546,5,0.903226,0.168725,-4.98923,1.644622,15,2.144787,1.282428,2.750535,-7.73977,-2.2387,Antagonistic
21,613,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase expression,Superoxide dismutase activity/expression,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.101,0.046,5,5,0.526,0.142,5,5,0.336,0.098,5,5,0.27,0.123,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.239,0.122,5,0.903226,0.122501,-3.75296,1.104237,15,2.144787,1.050827,2.253799,-6.00676,-1.49916,Antagonistic
21,614,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Superoxide dismutase expression,Superoxide dismutase activity/expression,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.101,0.046,5,5,0.526,0.142,5,5,0.27,0.026,5,5,0.275,0.128,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.305,0.102078,5,0.903226,0.115767,-4.52522,1.42388,15,2.144787,1.193264,2.559298,-7.08452,-1.96592,Antagonistic
21,615,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gstp1 expression,gstp1 activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.087,0.033,5,5,1.225,0.06,5,5,0.247,0.138,5,5,0.766,0.152,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.385,0.106405,5,0.903226,0.131198,-2.62297,0.743998,15,2.144787,0.862553,1.849993,-4.47296,-0.77298,Antagonistic
21,616,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gstp1 expression,gstp1 activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.087,0.033,5,5,1.225,0.06,5,5,0.321,0.183,5,5,1.055,0.046,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.459,0.136178,5,0.903226,0.101638,-5.29648,1.802634,15,2.144787,1.342622,2.879638,-8.17612,-2.41684,Antagonistic
21,617,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gstp1 expression,gstp1 activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.087,0.033,5,5,1.225,0.06,5,5,0.353,0.032,5,5,0.504,0.124,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,0.491,0.048083,5,0.903226,0.094043,-0.12486,0.400779,15,2.144787,0.633071,1.357803,-1.48266,1.232946,Additive
21,618,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gclc expression,gclc activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.579,0.119,5,5,2.786,1.194,5,5,1.928,0.523,5,5,2.557,1.069,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.135,0.921728,5,0.903226,0.998084,-0.52307,0.41368,15,2.144787,0.64318,1.379483,-1.90255,0.856416,Additive
21,619,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gclc expression,gclc activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.579,0.119,5,5,2.786,1.194,5,5,1.409,0.183,5,5,3.98,1.377,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.616,0.854144,5,0.903226,1.145795,1.075236,0.457807,15,2.144787,0.676614,1.451193,-0.37596,2.526429,Additive
21,620,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,gclc expression,gclc activity/expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.579,0.119,5,5,2.786,1.194,5,5,1.441,0.243,5,5,2.221,0.028,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,2.648,0.861593,5,0.903226,0.60956,-0.63271,0.420016,15,2.144787,0.648087,1.390008,-2.02272,0.757293,Additive
21,621,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase expression,Acetylcholinesterase expression/activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,2.712,0.213,5,5,3.345,0.923,5,5,3.345,0.588,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,4.579,0.669813,5,0.903226,0.630235,-1.76852,0.556382,15,2.144787,0.74591,1.599819,-3.36833,-0.1687,Antagonistic
21,622,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase expression,Acetylcholinesterase expression/activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,2.712,0.213,5,5,2.111,0.529,5,5,4.236,0.724,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.345,0.403243,5,0.903226,0.585995,1.373346,0.494304,15,2.144787,0.703068,1.50793,-0.13458,2.881276,Additive
21,623,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Acetylcholinesterase expression,Acetylcholinesterase expression/activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,2.712,0.213,5,5,2.007,0.66,5,5,1.795,0.013,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.241,0.490392,5.00E+00,0.903226,0.346881,-3.76516,1.108822,15,2.144787,1.053006,2.258473,-6.02363,-1.50669,Antagonistic
21,624,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallothionein 2 expression,Metallothionein 2 expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,0.361,0.109,5,5,0.348,0.045,5,5,0.257,0.059,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.769,0.083385,5,0.903226,0.072229,-12.8302,8.630696,15,2.144787,2.937805,6.300964,-19.1312,-6.52923,Antagonistic
21,625,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallothionein 2 expression,Metallothionein 2 expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,0.361,0.109,5,5,0.361,0.064,5,5,1.162,0.031,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.756,0.089378,5,0.903226,0.066894,-25.8977,33.93444,15,2.144787,5.825328,12.49409,-38.3917,-13.4036,Antagonistic
21,626,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Metallothionein 2 expression,Metallothionein 2 expression,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.478,0.059,5,5,0.361,0.109,5,5,0.316,0.154,5,5,0.316,0.154,5,5,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,-0.801,0.133411,5,0.903226,0.144074,-7.00269,2.85188,15,2.144787,1.688751,3.622011,-10.6247,-3.38067,Antagonistic
21,627,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Total distance moved,Total distance moved,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,228.91,45.186,5,25,247.761,33.451,5,25,195.018,44.015,5,25,203.892,77.468,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,213.869,39.09149,25,0.984293,61.3573,0.160051,0.080256,75,1.992543,0.283295,0.564478,-0.40443,0.724529,Additive
21,628,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Total distance moved,Total distance moved,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,228.91,45.186,5,25,247.761,33.451,5,25,184.601,94.484,5,25,224.579,51.646,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,203.452,70.87382,25,0.984293,62.00971,-0.33535,0.081125,75,1.992543,0.284824,0.567524,-0.90288,0.232171,Additive
21,629,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Total distance moved,Total distance moved,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,228.91,45.186,5,25,247.761,33.451,5,25,353.761,54.578,5,25,319.799,32.864,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,372.612,45.26438,25,0.984293,39.55317,-1.31427,0.097273,75,1.992543,0.311886,0.621447,-1.93572,-0.69282,Antagonistic
21,630,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Nearest neighbour distance,Nearest neighbour distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.194,0.047,5,25,1.152,0.053,5,25,1.135,0.059,5,25,1.123,0.053,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.093,0.05608,25,0.984293,0.054562,-0.5412,0.082929,75,1.992543,0.287974,0.5738,-1.115,0.032602,Additive
21,631,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Nearest neighbour distance,Nearest neighbour distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.194,0.047,5,25,1.152,0.053,5,25,1.176,0.047,5,25,1.152,0.053,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.134,0.05009,25,0.984293,0.051565,-0.34359,0.081181,75,1.992543,0.284922,0.567719,-0.91131,0.224132,Additive
21,632,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Nearest neighbour distance,Nearest neighbour distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,1.194,0.047,5,25,1.152,0.053,5,25,1.147,0.047,5,25,1.076,0.076,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,1.105,0.05009,25,0.984293,0.064362,0.443498,0.081967,75,1.992543,0.286299,0.570462,-0.12696,1.01396,Additive
21,633,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Inter-individual distance,Inter-individual distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.976,0.171,5,25,3.852,0.148,5,25,3.764,0.294,5,25,3.811,0.165,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.64,0.232744,25,0.984293,0.201736,-0.83433,0.086961,75,1.992543,0.294892,0.587584,-1.42191,-0.24674,Antagonistic
21,634,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Inter-individual distance,Inter-individual distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.976,0.171,5,25,3.852,0.148,5,25,3.852,0.106,5,25,3.858,0.247,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.728,0.128725,25,0.984293,0.196951,-0.6497,0.084221,75,1.992543,0.290209,0.578253,-1.22795,-0.07144,Antagonistic
21,635,Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper,Inorganic pollutants,Metal contaminants,Copper,4,,Inter-individual distance,Inter-individual distance,cm,Ecological,Inorganic pollutants X Ecological,N,2,mg/L,Micro g/L,N,4,Undisclosed,5,Spheres,Y,3.976,0.171,5,25,3.852,0.148,5,25,3.8,0.2,5,25,3.488,0.188,5,25,N,Santos,2020,Danio rerio,Danionidae,Larvae,Benthopelagic,3.676,0.175932,25,0.984293,0.182066,1.016374,0.09033,75,1.992543,0.30055,0.598858,0.417516,1.615233,Synergistic
22,640,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,nmol/min.mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.825,0.103,3,3,1.877,0.257,3,3,0.917,0.308,3,3,1.011,0.257,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.969,0.283649,3,0.8,0.270652,-0.12414,0.667951,9,2.306004,0.817283,1.884657,-2.0088,1.760513,Additive
22,641,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,nmol/min.mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.825,0.103,3,3,1.962,0.403,3,3,0.917,0.308,3,3,1.757,0.591,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,1.054,0.358659,3,0.8,0.488834,-1.15049,0.776969,9,2.306004,0.881459,2.032647,-3.18314,0.882155,Additive
22,646,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,EROD activity,EROD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.791,0.137,3,3,1.671,0.223,3,3,1.08,0.24,3,3,1.011,0.36,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.96,0.231656,3,0.8,0.302708,-0.13478,0.668181,9,2.306004,0.817423,1.884981,-2.01976,1.750198,Additive
22,647,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,EROD activity,EROD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.791,0.137,3,3,1.182,0.146,3,3,1.08,0.24,3,3,1.088,0.077,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.471,0.19864,3,0.8,0.150644,-3.27661,1.561346,9,2.306004,1.249538,2.881441,-6.15805,-0.39517,Antagonistic
22,652,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.534,0.072,3,3,1.419,0.158,3,3,0.965,0.202,3,3,0.554,0.144,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.85,0.181339,3,0.8,0.163738,1.446216,0.840962,9,2.306004,0.91704,2.114697,-0.66848,3.560914,Additive
22,653,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.534,0.072,3,3,1.404,0.173,3,3,0.965,0.202,3,3,1.246,0.079,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.835,0.18806,3,0.8,0.144235,-2.27961,1.099719,9,2.306004,1.048675,2.418249,-4.69786,0.138637,Additive
22,658,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Malondialdehyde content,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.156,0.013,3,3,0.192,0.016,3,3,0.172,0.022,3,3,0.202,0.006,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.208,0.019235,3,0.8,0.014248,-0.33689,0.676125,9,2.306004,0.822268,1.896154,-2.23305,1.55926,Additive
22,659,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,Malondialdehyde content,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.156,0.013,3,3,0.177,0.03,3,3,0.172,0.022,3,3,0.179,0.026,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.193,0.026306,3,0.8,0.026153,-0.42824,0.681949,9,2.306004,0.825802,1.904303,-2.33255,1.476061,Additive
22,664,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,BFCOD activity,BFCOD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.108,0.023,3,3,0.132,0.026,3,3,0.064,0.024,3,3,0.067,0.004,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.088,0.02502,3,0.8,0.017916,0.937685,0.739938,9,2.306004,0.860196,1.983616,-1.04593,2.921301,Additive
22,665,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,BFCOD activity,BFCOD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.108,0.023,3,3,0.122,0.014,3,3,0.064,0.024,3,3,0.095,0.015,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.078,0.019647,3,0.8,0.017479,-0.7781,0.717119,9,2.306004,0.846829,1.952791,-2.73089,1.174695,Additive
22,670,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,P-gp content,P-gp content,mg/L,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,59.597,6.443,3,3,68.859,0.402,3,3,74.899,0.805,3,3,43.087,2.013,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,84.161,0.63625,3,0.8,1.492813,-22.0116,41.04252,9,2.306004,6.406443,14.77329,-36.7849,-7.23831,Antagonistic
22,671,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Beta blockers,Propranolol,2,28 d,P-gp content,P-gp content,mg/L,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,59.597,6.443,3,3,70.872,2.013,3,3,74.899,0.805,3,3,35.033,3.624,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,86.174,1.533003,3,0.8,2.782398,-14.7042,18.68434,9,2.306004,4.322539,9.967793,-24.6719,-4.73636,Antagonistic
22,676,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,nmol/min.mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.837,0.1,3,3,1.887,0.248,3,3,1.362,0.227,3,3,0.818,0.17,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,1.412,0.237732,3,0.8,0.20666,2.299432,1.107282,9,2.306004,1.052275,2.42655,-0.12712,4.725982,Additive
22,677,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,nmol/min.mgProtein,Metabolic,Organic pollutants X Metabolic,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.837,0.1,3,3,1.97,0.397,3,3,1.362,0.227,3,3,1.503,0.205,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,1.495,0.323371,3,0.8,0.270734,-0.02364,0.666713,9,2.306004,0.816525,1.88291,-1.90655,1.859271,Additive
22,682,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,EROD activity,EROD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.83,0.131,3,3,1.71,0.218,3,3,0.976,0.253,3,3,1.142,0.24,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.856,0.236149,3,0.8,0.238082,-0.96101,0.743629,9,2.306004,0.862339,1.988557,-2.94957,1.027546,Additive
22,683,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,EROD activity,EROD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.83,0.131,3,3,1.217,0.153,3,3,0.976,0.253,3,3,1.326,0.349,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.363,0.209067,3,0.8,0.287672,-2.67805,1.264331,9,2.306004,1.124425,2.592928,-5.27098,-0.08513,Antagonistic
22,688,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.536,0.072,3,3,1.428,0.152,3,3,1.641,0.108,3,3,1.338,0.195,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,1.533,0.131848,3,0.8,0.166447,0.937237,0.739868,9,2.306004,0.860156,1.983523,-1.04629,2.92076,Additive
22,689,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,1.536,0.072,3,3,1.406,0.181,3,3,1.641,0.108,3,3,1.345,0.083,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,1.511,0.149039,3,0.8,0.120626,1.100919,0.767669,9,2.306004,0.876167,2.020445,-0.91953,3.121364,Additive
22,694,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Malondialdehyde content,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.164,0.018,3,3,0.192,0.016,3,3,0.17,0.033,3,3,0.111,0.009,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.198,0.025933,3,0.8,0.01941,-3.58577,1.738146,9,2.306004,1.318388,3.040208,-6.62598,-0.54556,Antagonistic
22,695,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,Malondialdehyde content,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.164,0.018,3,3,0.177,0.031,3,3,0.17,0.033,3,3,0.109,0.031,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.183,0.032016,3,0.8,0.031512,-1.87866,0.960779,9,2.306004,0.980193,2.26033,-4.13898,0.381674,Additive
22,700,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,BFCOD activity,BFCOD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.108,0.023,3,3,0.132,0.025,3,3,0.063,0.023,3,3,0.07,0.019,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.087,0.024021,3,0.8,0.021656,0.62799,0.699531,9,2.306004,0.83638,1.928695,-1.30071,2.556685,Additive
22,701,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,BFCOD activity,BFCOD activity,pmol/mg.Pro.min,Stress response,Organic pollutants X Stress response,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,0.108,0.023,3,3,0.121,0.015,3,3,0.063,0.023,3,3,0.105,0.027,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,0.076,0.019416,3,0.8,0.023516,-0.98656,0.747776,9,2.306004,0.86474,1.994095,-2.98066,1.00753,Additive
22,706,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,P-gp content,P-gp content,mg/L,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,59.799,6.401,3,3,68.829,0.602,3,3,49.364,21.472,3,3,36.722,3.01,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,58.394,15.18896,3,0.8,10.94908,1.583476,0.875616,9,2.306004,0.935744,2.157829,-0.57435,3.741304,Additive
22,707,Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging,Organic pollutants,Antibiotics,Sulfamethoxazole,2,28 d,P-gp content,P-gp content,mg/L,Biochemical,Organic pollutants X Biochemical,N,2,Micro g/L,Micro g/L,Y,14,PS,5,Beads,N,59.799,6.401,3,3,70.836,2.608,3,3,49.364,21.472,3,3,85.886,3.01,3,3,Y,Huang,2021,Oreochromis niloticus,Cichlidae,Juvenile,Benthopelagic,60.401,15.29458,3,0.8,11.02235,1.849697,0.951781,9,2.306004,0.975593,2.249721,-0.40002,4.099418,Additive
23,710,Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium,Inorganic pollutants,Metal contaminants,Cadmium,2,48 h,Heartbeat,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,3,mg/L,mg/L,Y,2,PET,150,Fragments,N,94.057,3.104,3,60,99.334,0,3,60,83.813,4.346,3,60,90.953,4.656,3,60,Y,Cheng,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,89.09,3.073086,60,0.993631,3.944756,-0.46926,0.034251,180,1.973305,0.18507,0.365199,-0.83446,-0.10407,Antagonistic
23,711,Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium,Inorganic pollutants,Metal contaminants,Cadmium,2,48 h,Heartbeat,Heart rate,bpm,Metabolic,Inorganic pollutants X Metabolic,Y,3,mg/L,mg/L,Y,2,PET,4999,Fibres,N,94.057,3.104,3,60,103.06,2.794,3,60,83.813,4.346,3,60,81.33,4.967,3,60,Y,Cheng,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,92.816,3.653365,60,0.993631,4.359941,2.61766,0.061884,180,1.973305,0.248765,0.490889,2.126771,3.108549,Synergistic
23,714,Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium,Inorganic pollutants,Metal contaminants,Cadmium,2,48 h,Bloodflow velocity,Bloodflow velocity,Micro m/s,Metabolic,Inorganic pollutants X Metabolic,N,3,mg/L,mg/L,Y,2,PET,150,Fragments,N,333.61,24.896,3,60,380.913,21.162,3,60,306.224,31.12,3,60,333.61,33.61,3,60,Y,Cheng,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,353.527,26.61094,60,0.993631,30.31315,-0.65286,0.035109,180,1.973305,0.187375,0.369747,-1.0226,-0.28311,Antagonistic
23,715,Toxicities of microplastic fibers and granules on the development of zebrafish embryos and their combined effects with cadmium,Inorganic pollutants,Metal contaminants,Cadmium,2,48 h,Bloodflow velocity,Bloodflow velocity,Micro m/s,Metabolic,Inorganic pollutants X Metabolic,N,3,mg/L,mg/L,Y,2,PET,4999,Fibres,N,333.61,24.896,3,60,388.382,43.568,3,60,306.224,31.12,3,60,363.485,28.631,3,60,Y,Cheng,2022,Danio rerio,Danionidae,Embryos,Benthopelagic,360.996,37.85911,60,0.993631,33.56372,0.073685,0.033356,180,1.973305,0.182636,0.360397,-0.28671,0.434082,Additive
24,716,Size-dependent impact of polystyrene microplastics on the toxicity of cadmium through altering neutrophil expression and metabolic regulation in zebrafish larvae,Inorganic pollutants,Metal contaminants,Cadmium,2,,Relative neutrophil level,Relative neutrophil level,Percent,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,mg/L,N,5,PS,350,Undisclosed,N,9.9689,99.4091,3,30,117.99,7.106,3,30,147.057,3.876,3,30,120.574,6.675,3,30,Y,Qin,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,255.0781,5.723575,30,0.987013,6.217513,-21.3522,3.865954,90,1.986979,1.966203,3.906803,-25.259,-17.4454,Antagonistic
24,717,Size-dependent impact of polystyrene microplastics on the toxicity of cadmium through altering neutrophil expression and metabolic regulation in zebrafish larvae,Inorganic pollutants,Metal contaminants,Cadmium,2,,Superoxide dismutase activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Inorganic pollutants X Stress response,Y,2,mg/L,mg/L,N,5,PS,350,Undisclosed,N,42.048,1.51,3,3,49.811,0.431,3,3,53.477,1.509,3,3,65.552,2.588,3,3,Y,Qin,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,61.24,1.109694,3,0.8,1.991126,1.732487,0.916793,9,2.306004,0.957493,2.207983,-0.4755,3.94047,Additive
24,718,Size-dependent impact of polystyrene microplastics on the toxicity of cadmium through altering neutrophil expression and metabolic regulation in zebrafish larvae,Inorganic pollutants,Metal contaminants,Cadmium,2,,Catalase activity,Catalase activity/expression,U/mgProtein,Metabolic,Inorganic pollutants X Metabolic,Y,2,mg/L,mg/L,N,5,PS,350,Undisclosed,N,22.237,0.404,3,3,21.496,0.741,3,3,12.331,0.27,3,3,20.956,2.224,3,3,Y,Qin,2021,Danio rerio,Danionidae,Larvae,Benthopelagic,11.59,0.557665,3,0.8,1.621291,-4.6215,2.446524,9,2.306004,1.564137,3.606906,-8.22841,-1.0146,Antagonistic
25,719,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,Number of MMC,Number of MMC,Number/mm2,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,27.256,3.894,3,6,44.601,5.31,3,6,95.575,18.407,3,6,84.955,17.346,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,112.92,13.54647,6,0.923077,15.56262,-1.65871,0.447971,18,2.109816,0.669307,1.412113,-3.07082,-0.24659,Antagonistic
25,720,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,MMCs area,MMCs area,Micro m2/mm2,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,3292.04,477.87,3,6,6690.27,902.65,3,6,14389.4,2601.8,3,6,14230.1,2867.2,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,17787.63,1947.324,6,0.923077,2450.807,-1.33992,0.408141,18,2.109816,0.638859,1.347874,-2.68779,0.007959,Additive
25,721,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,Pancreatic tissues with MMC,Pancreatic tissues with MMC,Percent,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,16.725,4.13,3,6,33.244,5.369,3,6,42.536,4.543,3,6,55.339,8.259,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,59.055,4.973179,6,0.923077,6.817022,-0.50317,0.343883,18,2.109816,0.586415,1.237228,-1.7404,0.734053,Additive
25,722,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,hsp70,hsp70,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.107,0.189,3,6,5.895,1.516,3,6,14.188,2.539,3,6,3.401,0.872,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,18.976,2.091026,6,0.923077,1.601994,-8.97439,3.689153,18,2.109816,1.920717,4.052358,-13.0267,-4.92203,Antagonistic
25,723,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,tumor necrosis factor,TNF level/expression,Relative expression,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.328,0.245,3,6,24.602,2.018,3,6,88.59,15.127,3,6,16.833,3.781,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,111.864,10.79116,6,0.923077,8.085332,-10.8494,5.237886,18,2.109816,2.288643,4.828614,-15.678,-6.02078,Antagonistic
25,724,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,il1b,IL-1B expression,Relative expression,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.109,0.235,3,6,12.705,1.849,3,6,4.336,1.042,3,6,12.907,1.042,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,15.932,1.500761,6,0.923077,1.291907,-2.16138,0.527983,18,2.109816,0.726624,1.533043,-3.69443,-0.62834,Antagonistic
25,725,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,Cyp1a1,Cyp1a1,Relative expression,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.171,0.268,3,6,0.882,0.234,3,6,0.118,0.028,3,6,0.748,0.2656,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,-0.171,0.166643,6,0.923077,0.221713,-3.82615,0.94331,18,2.109816,0.971241,2.04914,-5.87529,-1.77701,Antagonistic
25,726,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,gst,Glutathione S-transferase activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.051,0.148,3,6,2.185,0.302,3,6,0.245,0.06,3,6,1.726,0.243,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.379,0.21772,6,0.923077,0.230707,1.388377,0.41365,18,2.109816,0.643156,1.356941,0.031437,2.745318,Synergistic
25,727,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,Caspase 3,Caspase 3 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.044,0.161,3,6,1.709,0.179,3,6,0.843,0.152,3,6,0.308,0.04,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.508,0.16605,6,0.923077,0.120774,-9.17165,3.838296,18,2.109816,1.959157,4.13346,-13.3051,-5.03819,Antagonistic
25,728,"Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure",Inorganic pollutants,Metal contaminants,Copper,2,,Caspase 9,Caspase 9 activity,Relative expression,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,1.06,0.129,3,6,1.06,0.163,3,6,0.253,0.037,3,6,0.387,0.106,3,6,Y,Hoseini,2022,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.253,0.118191,6,0.923077,0.112261,-1.10183,0.383918,18,2.109816,0.619611,1.307265,-2.40909,0.205436,Additive
26,729,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,Cyp1a1,Cyp1a1,log^2 fold change,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,0.005,0.407,3,6,1.453,0.168,3,6,1.07,0.275,3,6,2.686,0.227,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,2.518,0.227869,6,0.923077,0.227435,0.681851,0.352705,18,2.109816,0.59389,1.252998,-0.57115,1.934849,Additive
26,730,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,hsp70,hsp70,log^2 fold change,Stress response,Inorganic pollutants X Stress response,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,-0.013,0.39,3,6,3.039,0.28,3,6,2.779,0.316,3,6,4.603,0.261,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.831,0.298543,6,0.923077,0.280401,-4.04257,1.014265,18,2.109816,1.007107,2.12481,-6.16738,-1.91776,Antagonistic
26,731,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,lys,Lysine,log^2 fold change,Biochemical,Inorganic pollutants X Biochemical,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,0.002,0.22,3,6,5.138,0.22,3,6,4.258,0.171,3,6,6.679,0.196,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,9.394,0.197029,6,0.923077,0.196515,-12.753,7.10993,18,2.109816,2.666445,5.625708,-18.3787,-7.12727,Antagonistic
26,732,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,def,Defensin,log^2 fold change,Immunological,Inorganic pollutants X Immunological,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,-0.01,0.151,3,6,5.239,0.228,3,6,4.459,0.266,3,6,4.934,0.229,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,9.708,0.24773,6,0.923077,0.238549,-18.4732,14.55253,18,2.109816,3.814778,8.048478,-26.5217,-10.4248,Antagonistic
26,733,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,muc2,muc2,log^2 fold change,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,-0.016,0.305,3,6,6.344,0.306,3,6,5.71,0.328,3,6,4.005,0.197,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,12.07,0.317191,6,0.923077,0.264026,-28.1966,33.46027,18,2.109816,5.784486,12.2042,-40.4008,-15.9924,Antagonistic
26,734,"Histopathological damage and stress- and immune-related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle",Inorganic pollutants,Metal contaminants,Copper,2,,muc5,muc5,log^2 fold change,Metabolic,Inorganic pollutants X Metabolic,N,2,mg/L,mg/L,N,14,PVC,200,Spheres,N,-0.016,0.13,3,6,3.59,0.196,3,6,3.573,0.148,3,6,2.672,0.147,3,6,Y,Hoseini,2021,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,7.179,0.173666,6,0.923077,0.160887,-25.8586,28.19454,18,2.109816,5.309853,11.20281,-37.0614,-14.6558,Antagonistic
27,735,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,6.06,0.485,3,30,19.428,1.486,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,19.493,5.102706,30,0.987013,3.758045,-0.01707,0.066669,90,1.986979,0.258204,0.513045,-0.53012,0.495973,Additive
27,736,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,6.06,0.485,3,30,22.4,7.314,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,19.493,5.102706,30,0.987013,6.306037,0.455,0.068392,90,1.986979,0.261518,0.519631,-0.06463,0.974631,Additive
27,737,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,9.696,1.213,3,30,25.485,5.715,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,23.129,5.162914,30,0.987013,5.445958,0.426996,0.068186,90,1.986979,0.261125,0.518849,-0.09185,0.945845,Additive
27,738,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,8.121,0.848,3,30,22.4,1.142,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,21.554,5.126359,30,0.987013,3.713739,0.224844,0.067088,90,1.986979,0.259013,0.514654,-0.28981,0.739498,Additive
27,739,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,10.181,1.212,3,30,25.142,1.143,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,23.614,5.162797,30,0.987013,3.739045,0.403353,0.068022,90,1.986979,0.260811,0.518226,-0.11487,0.921579,Additive
27,740,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,12.969,0.849,3,30,32,8.685,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,26.402,5.126441,30,0.987013,7.131256,0.7748,0.071669,90,1.986979,0.267711,0.531936,0.242864,1.306737,Synergistic
27,741,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,12.121,0.848,3,30,33.485,1.486,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,25.554,5.126359,30,0.987013,3.774106,2.074134,0.102517,90,1.986979,0.320183,0.636196,1.437938,2.71033,Synergistic
27,742,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,13.333,1.697,3,30,43.771,9.486,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,26.766,5.23067,30,0.987013,7.659768,2.191209,0.106678,90,1.986979,0.326616,0.64898,1.542229,2.840189,Synergistic
27,743,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,18.666,4,3,30,46.857,4.914,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,32.099,5.824088,30,0.987013,5.388293,2.703331,0.127567,90,1.986979,0.357165,0.709679,1.993652,3.41301,Synergistic
27,744,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,6.06,0.485,3,30,25.485,11.086,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,19.493,5.102706,30,0.987013,8.629514,0.685344,0.070581,90,1.986979,0.26567,0.527882,0.157462,1.213225,Synergistic
27,745,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,6.909,1.212,3,30,38.4,1.142,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,20.342,5.162797,30,0.987013,3.738893,4.767048,0.25604,90,1.986979,0.506004,1.005418,3.76163,5.772466,Synergistic
27,746,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,8.484,0.485,3,30,36.571,6.057,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,21.917,5.102706,30,0.987013,5.600217,2.582701,0.122253,90,1.986979,0.349647,0.694741,1.887961,3.277442,Synergistic
27,747,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,15.757,2.061,3,30,33.485,1.486,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,29.19,5.295645,30,0.987013,3.889219,1.089993,0.076567,90,1.986979,0.276708,0.549813,0.54018,1.639806,Synergistic
27,748,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,15.393,2.425,3,30,44.114,2.286,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,28.826,5.372179,30,0.987013,4.128323,3.655105,0.177998,90,1.986979,0.421898,0.838303,2.816802,4.493408,Synergistic
27,749,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,22.303,0.363,3,30,49.142,6.4,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,35.736,5.097635,30,0.987013,5.785581,2.287047,0.110255,90,1.986979,0.332046,0.659769,1.627278,2.946817,Synergistic
27,750,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,21.09,0.728,3,30,45.714,3.771,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,34.523,5.117127,30,0.987013,4.494743,2.457462,0.116993,90,1.986979,0.342042,0.67963,1.777832,3.137092,Synergistic
27,751,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,22.303,4.363,3,30,50.971,2.743,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,35.736,5.952973,30,0.987013,4.634756,3.24443,0.154386,90,1.986979,0.39292,0.780723,2.463707,4.025154,Synergistic
27,752,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Superoxide dismutase level,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,2.909,1.212,3,30,16.342,7.2,3,30,30.787,2.788,3,30,61.714,14.057,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,44.22,5.45953,30,0.987013,10.66315,1.619296,0.088518,90,1.986979,0.297519,0.591164,1.028132,2.21046,Synergistic
27,753,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,2.644,1.058,3,30,9.269,1.524,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,4.324,0.769376,30,0.987013,1.207169,-4.04316,0.202893,90,1.986979,0.450436,0.895007,-4.93817,-3.14815,Antagonistic
27,754,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,3.702,0.926,3,30,9.904,0.254,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,5.382,0.678967,30,0.987013,0.512597,-8.70717,0.698457,90,1.986979,0.835737,1.660592,-10.3678,-7.04658,Antagonistic
27,755,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,3.966,0,3,30,12.063,0,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,5.646,0.179605,30,0.987013,0.127,-49.8714,20.79294,90,1.986979,4.559927,9.060478,-58.9318,-40.8109,Antagonistic
27,756,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,4.363,0.926,3,30,12.063,1.651,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,6.043,0.678967,30,0.987013,1.262299,4.70714,0.25131,90,1.986979,0.501308,0.996088,3.711052,5.703229,Synergistic
27,757,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,7.272,0.397,3,30,14.603,1.27,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,8.952,0.33326,30,0.987013,0.928429,6.007576,0.367425,90,1.986979,0.606156,1.204418,4.803157,7.211994,Synergistic
27,758,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,7.933,1.323,3,30,16.507,3.81,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,9.613,0.952587,30,0.987013,2.777006,2.450289,0.116699,90,1.986979,0.341613,0.678777,1.771512,3.129067,Synergistic
27,759,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,6.611,1.058,3,30,18.793,2.54,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,8.291,0.769376,30,0.987013,1.876638,5.5235,0.320909,90,1.986979,0.566488,1.1256,4.397901,6.6491,Synergistic
27,760,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,7.933,0.397,3,30,22.222,1.016,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,9.613,0.33326,30,0.987013,0.756082,16.46019,2.324483,90,1.986979,1.524625,3.029398,13.43079,19.48959,Synergistic
27,761,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,15.206,1.058,3,30,25.396,1.27,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,16.886,0.769376,30,0.987013,1.049962,7.999796,0.599973,90,1.986979,0.774579,1.539072,6.460723,9.538868,Synergistic
27,762,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,4.363,0.926,3,30,10.793,2.54,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,6.043,0.678967,30,0.987013,1.859112,2.521801,0.119662,90,1.986979,0.345922,0.687341,1.834461,3.209142,Synergistic
27,763,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,6.611,0.661,3,30,11.809,2.159,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,8.291,0.500718,30,0.987013,1.567163,2.215667,0.107577,90,1.986979,0.327989,0.651706,1.563961,2.867374,Synergistic
27,764,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,6.611,1.322,3,30,16.888,3.81,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,8.291,0.951893,30,0.987013,2.776887,3.055706,0.144478,90,1.986979,0.380102,0.755255,2.300451,3.810962,Synergistic
27,765,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,5.95,1.058,3,30,16.507,2.54,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,7.63,0.769376,30,0.987013,1.876638,4.668836,0.248317,90,1.986979,0.498314,0.990139,3.678696,5.658975,Synergistic
27,766,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,9.917,1.058,3,30,20.317,1.016,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,11.597,0.769376,30,0.987013,0.901165,9.550698,0.826799,90,1.986979,0.909285,1.806729,7.743969,11.35743,Synergistic
27,767,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,13.619,2.645,3,30,25.142,5.08,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,15.299,1.878901,30,0.987013,3.829926,2.536646,0.120288,90,1.986979,0.346826,0.689135,1.847511,3.225782,Synergistic
27,768,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,13.223,1.983,3,30,28.952,2.54,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,14.903,1.413649,30,0.987013,2.055481,6.746132,0.445919,90,1.986979,0.667772,1.326848,5.419284,8.072981,Synergistic
27,769,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,22.876,1.322,3,30,32.381,1.269,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,24.556,0.951893,30,0.987013,1.121709,6.885367,0.461736,90,1.986979,0.679511,1.350175,5.535193,8.235542,Synergistic
27,770,"Enantiospecific toxicity, distribution and bioaccumulation of chiral antidepressant venlafaxine and its metabolite in loach (Misgurnus anguillicaudatus) co-exposed to microplastic and the drugs",Organic pollutants,Antidepressants,Venlafaxine,19,,Malondialdehyde level,Malondialdehyde levels,nmol/mgProtein,Stress response,Organic pollutants X Stress response,N,2,mg/L,Micro g/L,N,4,PVC,9,Undisclosed,N,5.685,0.662,3,30,7.365,0.254,3,30,30.413,1.983,3,30,35.555,1.27,3,30,Y,Qu,2019,Misgurnus anguillicaudatus,Cobitidae,Adult,Demersal,32.093,1.413649,30,0.987013,1.343745,2.542922,0.120554,90,1.986979,0.347209,0.689896,1.853026,3.232818,Synergistic
28,771,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/L,Metabolic,Inorganic pollutants X Metabolic,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,1489,110,3,24,1191,139,3,24,852,53,3,24,617,81,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,554,105.1903,24,0.983607,93.87758,-0.66009,0.087872,72,1.993943,0.296432,0.591069,-1.25115,-0.06902,Antagonistic
28,772,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/L,Metabolic,Inorganic pollutants X Metabolic,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,1489,110,3,24,1179,109,3,24,852,53,3,24,560,93,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,542,85.70298,24,0.983607,89.42595,-0.19798,0.083742,72,1.993943,0.289381,0.57701,-0.77499,0.379026,Additive
28,773,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/L,Metabolic,Inorganic pollutants X Metabolic,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,1489,110,3,24,1191,139,3,24,713,27,3,24,661,103,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,415,100.1249,24,0.983607,101.5726,-2.38221,0.142447,72,1.993943,0.377422,0.752557,-3.13477,-1.62965,Antagonistic
28,774,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/L,Metabolic,Inorganic pollutants X Metabolic,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,1489,110,3,24,1179,109,3,24,713,27,3,24,686,52,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,403,79.40403,24,0.983607,67.11557,-4.14748,0.262517,72,1.993943,0.512364,1.021625,-5.16911,-3.12586,Antagonistic
28,775,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Gamma-glutamyl-transferase activity,Gamma-glutamyl-transferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,33,1,3,24,21,0,3,24,14,1,3,24,10,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,2,0.707107,24,0.983607,0.866025,-9.08617,0.943317,72,1.993943,0.971245,1.936608,-11.0228,-7.14956,Antagonistic
28,776,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Gamma-glutamyl-transferase activity,Gamma-glutamyl-transferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,33,1,3,24,20,1,3,24,14,1,3,24,9,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1,1,24,0.983607,1,-7.86885,0.728321,72,1.993943,0.853417,1.701666,-9.57052,-6.16719,Antagonistic
28,777,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Gamma-glutamyl-transferase activity,Gamma-glutamyl-transferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,33,1,3,24,21,0,3,24,14,1,3,24,10,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,2,0.707107,24,0.983607,0.866025,-9.08617,0.943317,72,1.993943,0.971245,1.936608,-11.0228,-7.14956,Antagonistic
28,778,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Gamma-glutamyl-transferase activity,Gamma-glutamyl-transferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,33,1,3,24,20,1,3,24,14,1,3,24,11,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1,1,24,0.983607,1,-9.83607,1.091127,72,1.993943,1.04457,2.082814,-11.9189,-7.75325,Antagonistic
28,779,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Aspartate aminotransferase activity,Aspartate aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,45,3,3,24,48,4,3,24,68,4,3,24,68,13,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,71,4,24,0.983607,9.617692,-0.30681,0.084314,72,1.993943,0.290369,0.578978,-0.88579,0.272167,Additive
28,780,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Aspartate aminotransferase activity,Aspartate aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,45,3,3,24,55,8,3,24,68,4,3,24,65,10,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,78,6.324555,24,0.983607,8.3666,-1.52833,0.107664,72,1.993943,0.328122,0.654258,-2.18258,-0.87407,Antagonistic
28,781,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Aspartate aminotransferase activity,Aspartate aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,45,3,3,24,48,4,3,24,81,7,3,24,74,8,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,84,5.700877,24,0.983607,6.946222,-1.41603,0.10422,72,1.993943,0.322832,0.643708,-2.05974,-0.77232,Antagonistic
28,782,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Aspartate aminotransferase activity,Aspartate aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,45,3,3,24,55,8,3,24,81,7,3,24,76,12,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,91,7.516648,24,0.983607,10.01249,-1.47357,0.105952,72,1.993943,0.325503,0.649034,-2.1226,-0.82453,Antagonistic
28,783,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alanine aminotransferase activity,Alanine aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,9,1,3,24,13,1,3,24,13,1,3,24,5,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,17,1,24,0.983607,1,-11.8033,1.534556,72,1.993943,1.238772,2.470041,-14.2733,-9.33324,Antagonistic
28,784,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alanine aminotransferase activity,Alanine aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,9,1,3,24,13,1,3,24,13,1,3,24,5,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,17,1,24,0.983607,1,-11.8033,1.534556,72,1.993943,1.238772,2.470041,-14.2733,-9.33324,Antagonistic
28,785,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alanine aminotransferase activity,Alanine aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,9,1,3,24,13,1,3,24,17,2,3,24,5,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,21,1.581139,24,0.983607,1.322876,-11.8966,1.557591,72,1.993943,1.248035,2.488511,-14.3851,-9.40808,Antagonistic
28,786,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alanine aminotransferase activity,Alanine aminotransferase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,9,1,3,24,13,1,3,24,17,2,3,24,4,1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,21,1.581139,24,0.983607,1.322876,-12.6401,1.747632,72,1.993943,1.321981,2.635954,-15.2761,-10.0042,Antagonistic
28,787,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,145,9,3,24,167,11,3,24,235,22,3,24,335,20,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,257,17.39253,24,0.983607,18.74166,4.093623,0.257893,72,1.993943,0.507832,1.012588,3.081035,5.106211,Synergistic
28,788,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,145,9,3,24,182,5,3,24,235,22,3,24,331,16,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,272,15.95306,24,0.983607,15.97655,3.632374,0.220772,72,1.993943,0.469864,0.936882,2.695491,4.569256,Synergistic
28,789,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,145,9,3,24,167,11,3,24,223,12,3,24,338,19,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,245,11.51086,24,0.983607,15.70828,5.823389,0.436582,72,1.993943,0.660743,1.317485,4.505904,7.140874,Synergistic
28,790,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lactate dehydrogenase activity,Lactate dehydrogenase activity/level,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,145,9,3,24,182,5,3,24,223,12,3,24,362,21,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,260,9.192388,24,0.983607,16.20957,6.189424,0.482385,72,1.993943,0.694539,1.384872,4.804551,7.574296,Synergistic
28,791,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,59,6,3,24,79,3,3,24,90,7,3,24,99,6,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,110,5.385165,24,0.983607,5.700877,-1.8979,0.120854,72,1.993943,0.347641,0.693176,-2.59107,-1.20472,Antagonistic
28,792,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,59,6,3,24,76,5,3,24,90,7,3,24,101,6,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,107,6.082763,24,0.983607,6.041523,-0.97685,0.093273,72,1.993943,0.305407,0.608964,-1.58581,-0.36788,Antagonistic
28,793,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,59,6,3,24,79,3,3,24,105,6,3,24,104,2,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,125,4.743416,24,0.983607,3.640055,-5.67457,0.418757,72,1.993943,0.647115,1.29031,-6.96488,-4.38426,Antagonistic
28,794,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/L,Metabolic,Inorganic pollutants X Metabolic,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,59,6,3,24,76,5,3,24,105,6,3,24,43,6,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,122,5.522681,24,0.983607,5.766281,-13.4757,1.974954,72,1.993943,1.405331,2.80215,-16.2779,-10.6736,Antagonistic
28,795,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Cholesterol,Cholesterol level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,75.6,10.44,3,24,123.37,16.9,3,24,149.95,12.96,3,24,143.72,11.07,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,197.72,15.05941,24,0.983607,13.2161,-4.01894,0.251582,72,1.993943,0.50158,1.000122,-5.01906,-3.01882,Antagonistic
28,796,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Cholesterol,Cholesterol level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,75.6,10.44,3,24,111.01,8.28,3,24,149.95,12.96,3,24,149.13,21.05,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,185.36,10.87474,24,0.983607,16.75354,-2.12708,0.130463,72,1.993943,0.361197,0.720206,-2.84728,-1.40687,Antagonistic
28,797,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Cholesterol,Cholesterol level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,75.6,10.44,3,24,123.37,16.9,3,24,145.17,11.79,3,24,166.04,12.69,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,192.94,14.57076,24,0.983607,13.66278,-1.93658,0.122399,72,1.993943,0.349856,0.697593,-2.63417,-1.23898,Antagonistic
28,798,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Cholesterol,Cholesterol level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,75.6,10.44,3,24,111.01,8.28,3,24,145.17,11.79,3,24,152.13,7.52,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,180.58,10.18731,24,0.983607,8.953537,-3.12542,0.185086,72,1.993943,0.430217,0.857827,-3.98325,-2.2676,Antagonistic
28,799,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Triglycerides,Triglyceride level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,174.55,14.58,3,24,211.52,10.24,3,24,283.61,11.1,3,24,293.28,19.31,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,320.58,10.67866,24,0.983607,15.60304,-1.72098,0.114185,72,1.993943,0.337913,0.673779,-2.39475,-1.0472,Antagonistic
28,800,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Triglycerides,Triglyceride level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,174.55,14.58,3,24,214.54,9.87,3,24,283.61,11.1,3,24,278.05,28.55,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,323.6,10.50302,24,0.983607,21.51065,-2.08284,0.128523,72,1.993943,0.358501,0.714831,-2.79767,-1.36801,Antagonistic
28,801,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Triglycerides,Triglyceride level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,174.55,14.58,3,24,211.52,10.24,3,24,300.07,16.33,3,24,285.73,36.99,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,337.04,13.6295,24,0.983607,27.87493,-1.81055,0.11748,72,1.993943,0.342754,0.683431,-2.49398,-1.12712,Antagonistic
28,802,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Triglycerides,Triglyceride level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,174.55,14.58,3,24,214.54,9.87,3,24,300.07,16.33,3,24,279.97,20.28,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,340.06,13.49233,24,0.983607,17.22384,-3.43158,0.205997,72,1.993943,0.453869,0.904989,-4.33657,-2.52659,Antagonistic
28,803,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Glucose,Glucose level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,51.78,3.13,3,24,67.6,3.31,3,24,80.9,4.15,3,24,79.57,1.48,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,96.72,3.753572,24,0.983607,2.853042,-5.91258,0.447486,72,1.993943,0.668944,1.333836,-7.24642,-4.57875,Antagonistic
28,804,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Glucose,Glucose level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,51.78,3.13,3,24,66.85,4.51,3,24,80.9,4.15,3,24,95.33,4.76,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,95.97,4.33374,24,0.983607,4.551862,-0.1383,0.083533,72,1.993943,0.28902,0.57629,-0.71459,0.437993,Additive
28,805,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Glucose,Glucose level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,51.78,3.13,3,24,67.6,3.31,3,24,82.87,7.27,3,24,86.44,2.63,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,98.69,5.648407,24,0.983607,4.405758,-2.73487,0.161245,72,1.993943,0.401553,0.800674,-3.53555,-1.9342,Antagonistic
28,806,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Glucose,Glucose level,mg/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,51.78,3.13,3,24,66.85,4.51,3,24,82.87,7.27,3,24,86.31,4.68,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,97.94,6.049504,24,0.983607,5.408276,-2.11516,0.129936,72,1.993943,0.360467,0.71875,-2.83391,-1.39641,Antagonistic
28,807,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total protein,Total protein level,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,4.77,0.17,3,24,3.89,0.41,3,24,2.71,0.24,3,24,2.53,0.26,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.83,0.335932,24,0.983607,0.300375,-2.29222,0.138065,72,1.993943,0.371571,0.740892,-3.03311,-1.55133,Antagonistic
28,808,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total protein,Total protein level,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,4.77,0.17,3,24,3.42,0.21,3,24,2.71,0.24,3,24,2.59,0.24,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.36,0.225499,24,0.983607,0.232863,-5.19549,0.364512,72,1.993943,0.603748,1.20384,-6.39933,-3.99165,Antagonistic
28,809,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total protein,Total protein level,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,4.77,0.17,3,24,3.89,0.41,3,24,2.81,0.11,3,24,2.79,0.15,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.93,0.300167,24,0.983607,0.237276,-3.56505,0.215725,72,1.993943,0.464462,0.926111,-4.49116,-2.63894,Antagonistic
28,810,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total protein,Total protein level,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,4.77,0.17,3,24,3.42,0.21,3,24,2.81,0.11,3,24,2.72,0.18,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.46,0.167631,24,0.983607,0.173925,-7.12573,0.61225,72,1.993943,0.782464,1.560189,-8.68592,-5.56554,Antagonistic
28,811,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Albumin,Albumin,g/dL,Biochemical,Inorganic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.27,0.27,3,24,1.92,0.17,3,24,1.9,0.08,3,24,1.84,0.29,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.55,0.132853,24,0.983607,0.225555,-1.26464,0.099993,72,1.993943,0.316217,0.630518,-1.89516,-0.63412,Antagonistic
28,812,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Albumin,Albumin,g/dL,Biochemical,Inorganic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.27,0.27,3,24,1.77,0.2,3,24,1.9,0.08,3,24,1.82,0.3,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.4,0.152315,24,0.983607,0.237908,-1.73645,0.114742,72,1.993943,0.338736,0.675421,-2.41187,-1.06103,Antagonistic
28,813,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Albumin,Albumin,g/dL,Biochemical,Inorganic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.27,0.27,3,24,1.92,0.17,3,24,1.94,0.1,3,24,1.91,0.1,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.59,0.139463,24,0.983607,0.121347,-2.59384,0.153417,72,1.993943,0.391685,0.780997,-3.37484,-1.81285,Antagonistic
28,814,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Albumin,Albumin,g/dL,Biochemical,Inorganic pollutants X Biochemical,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.27,0.27,3,24,1.77,0.2,3,24,1.94,0.1,3,24,1.83,0.23,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.44,0.158114,24,0.983607,0.197358,-1.94371,0.122688,72,1.993943,0.350268,0.698415,-2.64213,-1.2453,Antagonistic
28,815,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Globulins,Globulin levels,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.5,0.29,3,24,1.97,0.41,3,24,0.8,0.24,3,24,0.69,0.26,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.27,0.335932,24,0.983607,0.300375,-1.37533,0.103037,72,1.993943,0.320994,0.640043,-2.01537,-0.73529,Antagonistic
28,816,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Globulins,Globulin levels,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.5,0.29,3,24,1.66,0.34,3,24,0.8,0.24,3,24,0.77,0.27,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,-0.04,0.294279,24,0.983607,0.2824,-2.82125,0.166244,72,1.993943,0.40773,0.812991,-3.63424,-2.00826,Antagonistic
28,817,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Globulins,Globulin levels,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.5,0.29,3,24,1.97,0.41,3,24,0.87,0.1,3,24,0.88,0.21,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.34,0.298412,24,0.983607,0.258021,-2.05854,0.127475,72,1.993943,0.357036,0.71191,-2.77045,-1.34663,Antagonistic
28,818,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Globulins,Globulin levels,g/dL,Biochemical,Inorganic pollutants X Biochemical,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,2.5,0.29,3,24,1.66,0.34,3,24,0.87,0.1,3,24,0.89,0.27,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.03,0.250599,24,0.983607,0.26048,-3.24747,0.193188,72,1.993943,0.439532,0.876401,-4.12387,-2.37107,Antagonistic
28,819,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total immunoglobulins,Total immunoglobulins,mg/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,15.58,3.33,3,24,11.3,1.76,3,24,5.09,1.31,3,24,7.14,1.22,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,0.81,1.551403,24,0.983607,1.395573,-4.46141,0.290669,72,1.993943,0.539137,1.075009,-5.53642,-3.3864,Antagonistic
28,820,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total immunoglobulins,Total immunoglobulins,mg/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,15.58,3.33,3,24,10.21,1.32,3,24,5.09,1.31,3,24,6.85,1.41,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,-0.28,1.31501,24,0.983607,1.363332,-5.1441,0.358976,72,1.993943,0.599146,1.194664,-6.33876,-3.94943,Antagonistic
28,821,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total immunoglobulins,Total immunoglobulins,mg/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,15.58,3.33,3,24,11.3,1.76,3,24,7.09,1.66,3,24,5.02,1.72,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,2.81,1.710731,24,0.983607,1.715372,-1.26723,0.100061,72,1.993943,0.316324,0.630733,-1.89796,-0.6365,Antagonistic
28,822,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Total immunoglobulins,Total immunoglobulins,mg/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,15.58,3.33,3,24,10.21,1.32,3,24,7.09,1.66,3,24,3.38,0.81,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,1.72,1.499667,24,0.983607,1.205218,-1.35476,0.102452,72,1.993943,0.320081,0.638224,-1.99299,-0.71654,Antagonistic
28,823,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,ACH50,ACH50,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,105.91,8.86,3,24,83.67,2.01,3,24,83.04,4.03,3,24,87.39,4.5,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,60.8,3.184415,24,0.983607,3.898109,-6.70943,0.552255,72,1.993943,0.743139,1.481776,-8.19121,-5.22766,Antagonistic
28,824,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,ACH50,ACH50,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,105.91,8.86,3,24,87.8,3.02,3,24,83.04,4.03,3,24,83.26,4.33,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,64.93,3.56099,24,0.983607,3.964187,-4.5481,0.298804,72,1.993943,0.54663,1.089949,-5.63805,-3.45815,Antagonistic
28,825,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,ACH50,ACH50,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,105.91,8.86,3,24,83.67,2.01,3,24,74.54,0.88,3,24,79.18,14.09,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,52.3,1.551532,24,0.983607,10.02336,-2.63777,0.155811,72,1.993943,0.394729,0.787067,-3.42484,-1.85071,Antagonistic
28,826,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,ACH50,ACH50,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,105.91,8.86,3,24,87.8,3.02,3,24,74.54,0.88,3,24,72.89,9.92,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,56.43,2.224275,24,0.983607,7.188665,-2.25218,0.13617,72,1.993943,0.369012,0.735789,-2.98797,-1.51639,Antagonistic
28,827,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C3,Complement C3 level/expression,mg/dL,Immunological,Inorganic pollutants X Immunological,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,16.88,2.24,3,24,11.71,1.69,3,24,10.84,1.34,3,24,9.24,2.03,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.67,1.525074,24,0.983607,1.795376,-1.95584,0.12318,72,1.993943,0.350971,0.699816,-2.65566,-1.25603,Antagonistic
28,828,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C3,Complement C3 level/expression,mg/dL,Immunological,Inorganic pollutants X Immunological,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,16.88,2.24,3,24,10.94,1.73,3,24,10.84,1.34,3,24,11.16,2.5,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4.9,1.547336,24,0.983607,2.078972,-2.96174,0.174707,72,1.993943,0.41798,0.833429,-3.79517,-2.12831,Antagonistic
28,829,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C3,Complement C3 level/expression,mg/dL,Immunological,Inorganic pollutants X Immunological,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,16.88,2.24,3,24,11.71,1.69,3,24,10.49,0.97,3,24,8.2,1.67,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.32,1.377861,24,0.983607,1.530915,-1.85039,0.118999,72,1.993943,0.344963,0.687836,-2.53822,-1.16255,Antagonistic
28,830,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C3,Complement C3 level/expression,mg/dL,Immunological,Inorganic pollutants X Immunological,Y,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,16.88,2.24,3,24,10.94,1.73,3,24,10.49,0.97,3,24,7.88,1.7,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,4.55,1.402462,24,0.983607,1.558348,-2.10185,0.129352,72,1.993943,0.359655,0.717132,-2.81898,-1.38472,Antagonistic
28,831,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C4,Complement C4,mg/dL,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,21.52,0.5,3,24,16.02,1.22,3,24,12,0.39,3,24,7.24,0.65,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,6.5,0.905677,24,0.983607,0.788273,-0.92337,0.092215,72,1.993943,0.303669,0.605498,-1.52887,-0.31787,Antagonistic
28,832,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C4,Complement C4,mg/dL,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,21.52,0.5,3,24,15.69,1.26,3,24,12,0.39,3,24,7.34,0.92,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,6.17,0.932657,24,0.983607,0.92635,-1.24232,0.09941,72,1.993943,0.315293,0.628677,-1.87099,-0.61364,Antagonistic
28,833,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C4,Complement C4,mg/dL,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,21.52,0.5,3,24,16.02,1.22,3,24,11.44,1.35,3,24,8.6,1.38,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.94,1.286643,24,0.983607,1.334138,-1.96111,0.123395,72,1.993943,0.351277,0.700426,-2.66154,-1.26069,Antagonistic
28,834,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Complement C4,Complement C4,mg/dL,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,21.52,0.5,3,24,15.69,1.26,3,24,11.44,1.35,3,24,8.48,0.76,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,5.61,1.305776,24,0.983607,1.068328,-2.6424,0.156065,72,1.993943,0.395051,0.78771,-3.43011,-1.85469,Antagonistic
28,835,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lysozyme,Lysozyme activity,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,30.86,1.09,3,24,23.05,1.1,3,24,16.73,1.29,3,24,12.64,0.7,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,8.92,1.19877,24,0.983607,0.981593,-3.72763,0.228075,72,1.993943,0.477572,0.952252,-4.67988,-2.77538,Antagonistic
28,836,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lysozyme,Lysozyme activity,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,30.86,1.09,3,24,23.88,0.52,3,24,16.73,1.29,3,24,12.08,0.54,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,9.75,0.983489,24,0.983607,0.793363,-2.88872,0.170257,72,1.993943,0.412622,0.822746,-3.71147,-2.06597,Antagonistic
28,837,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lysozyme,Lysozyme activity,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,30.86,1.09,3,24,23.05,1.1,3,24,17.18,1.18,3,24,11.27,0.23,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,9.37,1.140702,24,0.983607,0.82283,-2.27125,0.137068,72,1.993943,0.370228,0.738213,-3.00946,-1.53304,Antagonistic
28,838,Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio),Inorganic pollutants,Metal contaminants,Cadmium,3,,Lysozyme,Lysozyme activity,U/ml,Immunological,Inorganic pollutants X Immunological,N,3,Micro g/L,Micro g/L,N,30,PE,Undisclosed,Undisclosed,N,30.86,1.09,3,24,23.88,0.52,3,24,17.18,1.18,3,24,11.48,0.25,3,24,N,Banaee,2019,Cyprinus carpio,Cyprinidae,Juvenile,Benthopelagic,10.2,0.911811,24,0.983607,0.668543,-1.88322,0.120276,72,1.993943,0.346809,0.691517,-2.57474,-1.19171,Antagonistic
29,839,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Mortality,Mortality,Percent,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,0,0,3,90,1,1,3,90,3,4,3,90,2,1,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,4,2.915476,90,0.995781,2.179449,-0.91379,0.024542,270,1.968822,0.156658,0.308432,-1.22222,-0.60536,Antagonistic
29,840,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Mortality,Mortality,Percent,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,0,0,3,90,0,0,3,90,3,4,3,90,4,3,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,3,2.828427,90,0.995781,2.915476,0.34155,0.022546,270,1.968822,0.150154,0.295627,0.045923,0.637177,Synergistic
29,841,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Time to hatch,Time to hatch,Days of exposure,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,12,2,3,90,12,1,3,90,10,2,3,90,10,2,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,10,1.581139,90,0.995781,1.802776,0,0.022222,270,1.968822,0.149071,0.293495,-0.29349,0.293495,Additive
29,842,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Time to hatch,Time to hatch,Days of exposure,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,12,2,3,90,11,2,3,90,10,2,3,90,10,2,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,9,2,90,0.995781,2,-0.49789,0.022911,270,1.968822,0.151363,0.298007,-0.7959,-0.19988,Antagonistic
29,843,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Heart rate,Heart rate,bpm,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,56,4,3,90,55,2,3,90,56,1,3,90,54,4,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,55,1.581139,90,0.995781,3.041381,0.327411,0.02252,270,1.968822,0.150067,0.295454,0.031956,0.622865,Synergistic
29,844,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Heart rate,Heart rate,bpm,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,56,4,3,90,56,2,3,90,56,1,3,90,55,2,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,56,1.581139,90,0.995781,1.802776,-0.55236,0.02307,270,1.968822,0.151887,0.299039,-0.8514,-0.25332,Antagonistic
29,845,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Larvae resting on side,Larvae resting on side,Percent,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,10,11.9,3,90,5.6,4.2,3,90,97.8,3.1,3,90,98.9,1.6,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,93.4,3.691206,90,0.995781,2.844732,1.925241,0.032518,270,1.968822,0.180328,0.355034,1.570207,2.280274,Synergistic
29,846,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Larvae resting on side,Larvae resting on side,Percent,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,10,11.9,3,90,1.1,1.6,3,90,97.8,3.1,3,90,100,0,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,88.9,2.466779,90,0.995781,1.744276,6.33682,0.133765,270,1.968822,0.365739,0.720074,5.616746,7.056894,Synergistic
29,847,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Total distance moved,Total distance moved,cm,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2135,862,3,90,1617,1008,3,90,224,95,3,90,253,136,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,-294,715.9221,90,0.995781,515.2866,-1.05707,0.025326,270,1.968822,0.159142,0.313322,-1.37039,-0.74374,Antagonistic
29,848,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Total distance moved,Total distance moved,cm,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2135,862,3,90,1772,1103,3,90,224,95,3,90,345,165,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,-139,782.8263,90,0.995781,565.704,-0.85196,0.024238,270,1.968822,0.155687,0.30652,-1.15848,-0.54544,Antagonistic
29,849,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Body contact,Body contact,s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,75,31,3,90,77,49,3,90,217,137,3,90,241,137,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,219,102.8834,90,0.995781,121.1487,0.180829,0.022313,270,1.968822,0.149376,0.294094,-0.11327,0.474923,Additive
29,850,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Body contact,Body contact,s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,75,31,3,90,56,17,3,90,217,137,3,90,222,63,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,198,97.6166,90,0.995781,82.1523,0.290908,0.022457,270,1.968822,0.149858,0.295043,-0.00414,0.585951,Additive
29,851,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Mean velocity,Velocity,cm/s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2,0.8,3,90,1.5,0.9,3,90,0.2,0.1,3,90,0.2,0.1,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,-0.3,0.640312,90,0.995781,0.458258,-1.08649,0.025501,270,1.968822,0.159691,0.314403,-1.40089,-0.77208,Antagonistic
29,852,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Mean velocity,Velocity,cm/s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2,0.8,3,90,1.6,1,3,90,0.2,0.1,3,90,0.3,0.2,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,-0.2,0.710634,90,0.995781,5.22E-01,-0.95378,0.024749,270,1.968822,0.157319,0.309733,-1.26352,-0.64405,Antagonistic
29,853,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,No movement,No movement,s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,579,207,3,90,706,243,3,90,1050,20,3,90,1049,28,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,1177,172.4079,90,0.995781,123.5081,-1.032,0.025181,270,1.968822,0.158684,0.31242,-1.34442,-0.71958,Antagonistic
29,854,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,No movement,No movement,s,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,579,207,3,90,668,282,3,90,1050,20,3,90,1025,36,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,1139,199.905,90,0.995781,143.628,-0.79037,0.023957,270,1.968822,0.154782,0.304738,-1.09511,-0.48563,Antagonistic
29,855,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Length,Body length/body length growth,cm,Ecological,Organic pollutants X Ecological,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2.7,0.1,3,90,2.6,0.1,3,90,2.4,0.1,3,90,2.4,0.1,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,2.3,0.1,90,0.995781,0.1,-0.99578,0.024977,270,1.968822,0.15804,0.311152,-1.30693,-0.68463,Antagonistic
29,856,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Length,Body length/body length growth,cm,Ecological,Organic pollutants X Ecological,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,2.7,0.1,3,90,2.7,0.1,3,90,2.4,0.1,3,90,2.4,0.1,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,2.4,0.1,90,0.995781,0.1,-4.42E-15,0.022222,270,1.968822,0.149071,0.293495,-0.29349,0.293495,Additive
29,857,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Body mass,Body mass/body mass growth,g,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,0.14,0.03,3,90,0.14,0.02,3,90,0.11,0.02,3,90,0.11,0.02,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,0.11,0.02,90,0.995781,0.02,-6.91E-16,0.022222,270,1.968822,0.149071,0.293495,-0.29349,0.293495,Additive
29,858,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Body mass,Body mass/body mass growth,g,Ecological,Organic pollutants X Ecological,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,0.14,0.03,3,90,0.15,0.02,3,90,0.11,0.02,3,90,0.12,0.02,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,0.12,0.02,90,0.995781,0.02,0,0.022222,270,1.968822,0.149071,0.293495,-0.29349,0.293495,Additive
29,859,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Superoxide dismutase,Superoxide dismutase activity/expression,U/ml,Stress response,Organic pollutants X Stress response,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,117.54,28.89,3,90,122.62,28.11,3,90,137.88,33.58,3,90,133.66,29.16,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,142.96,30.96602,90,0.995781,30.07657,-0.30791,0.022486,270,1.968822,0.149952,0.295229,-0.60313,-0.01268,Antagonistic
29,860,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Superoxide dismutase,Superoxide dismutase activity/expression,U/ml,Stress response,Organic pollutants X Stress response,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,117.54,28.89,3,90,121.55,24.58,3,90,137.88,33.58,3,90,129.09,31.48,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,141.89,29.42612,90,0.995781,30.47037,-0.41831,0.022708,270,1.968822,0.150693,0.296687,-0.71499,-0.12162,Antagonistic
29,861,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,52.46,12.66,3,90,54.48,13.04,3,90,68.29,13.59,3,90,68.53,14.7,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,70.31,13.31784,90,0.995781,1.40E+01,-0.12637,0.022267,270,1.968822,0.14922,0.293787,-0.42016,0.167415,Additive
29,862,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,52.46,12.66,3,90,53.69,12.39,3,90,68.29,13.59,3,90,68.87,14.78,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,69.52,13.00385,90,0.995781,13.92028,-0.0465,0.022228,270,1.968822,0.149091,0.293534,-0.34003,0.247037,Additive
29,863,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,CbE-pnpa activity,CbE-pnpa activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,69.21,22.85,3,90,70.25,17.96,3,90,59.23,14.1,3,90,54.11,23.21,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,60.27,16.14577,90,0.995781,19.99237,0.306817,0.022484,270,1.968822,0.149946,0.295216,0.011601,0.602034,Synergistic
29,864,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,CbE-pnpa activity,CbE-pnpa activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,69.21,22.85,3,90,70.15,17.54,3,90,59.23,14.1,3,90,57.22,15.89,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,60.17,15.91323,90,0.995781,15.90162,0.184733,0.022317,270,1.968822,0.149389,0.29412,-0.10939,0.478853,Additive
29,865,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,CbE-pnpv activity,CbE-pnpv activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,70.28,24.04,3,90,66.15,21.79,3,90,39.12,26.11,3,90,38.27,27.86,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,34.99,24.04721,90,0.995781,26.02352,-0.12551,0.022266,270,1.968822,0.149218,0.293783,-0.41929,0.168275,Additive
29,866,Interacting Effects of Polystyrene Microplastics and the Antidepressant Amitriptyline on Early Life Stages of Brown Trout (Salmo trutta f. fario),Organic pollutants,Antidepressants,Amitriptyline,2,,CbE-pnpv activity,CbE-pnpv activity,mu/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Particles/L,Microg/L,N,60,PS,49,Fragments,N,70.28,24.04,3,90,70.43,21.51,3,90,39.12,26.11,3,90,31.33,23.59,3,90,N,Schmieg,2020,Salmo trutta,Salmonidae,Larvae,Pelagic,39.27,23.92083,90,0.995781,23.75599,0.332821,0.02253,270,1.968822,0.1501,0.29552,0.037302,0.628341,Synergistic
30,867,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Aspartate acid,Aspartate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,23.71,2.57,3,6,32.38,0.67,3,6,24.63,2.12,3,6,39.55,1.3,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,33.3,1.572148,6.00E+00,0.923077,1.442506,3.999449,0.999816,18,2.109816,0.999908,2.109622,1.889827,6.10907,Synergistic
30,868,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Aspartate acid,Aspartate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,23.71,2.57,3,6,24.2,1.59,3,6,24.63,2.12,3,6,19.71,2.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,25.12,1.873833,6,0.923077,1.979602,-2.52265,0.59849,18,2.109816,0.773622,1.632199,-4.15485,-0.89045,Antagonistic
30,869,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Aspartate acid,Aspartate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,23.71,2.57,3,6,32.38,0.67,3,6,16.22,0.96,3,6,33.89,1.09,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,24.89,0.827798,6,0.923077,0.96782,8.583925,3.403491,18,2.109816,1.844855,3.892304,4.691621,12.47623,Synergistic
30,870,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Aspartate acid,Aspartate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,23.71,2.57,3,6,24.2,1.59,3,6,16.22,0.96,3,6,31.58,0.61,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,16.71,1.313335,6,0.923077,1.023951,-13.4051,7.820688,18,2.109816,2.796549,5.900203,-19.3053,-7.50489,Antagonistic
30,871,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glutamate acid,Glutamate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,43.1,2.04,3,6,43.73,1.84,3,6,46.09,0.67,3,6,52.69,0.12,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,46.72,1.384648,6,0.923077,0.982764,5.607419,1.643464,18,2.109816,1.281977,2.704735,2.902684,8.312154,Synergistic
30,872,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glutamate acid,Glutamate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,43.1,2.04,3,6,41.49,1.08,3,6,46.09,0.67,3,6,33.48,0.5,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,44.48,0.898693,6,0.923077,0.727204,-13.9629,8.456735,18,2.109816,2.908047,6.135442,-20.0983,-7.82742,Antagonistic
30,873,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glutamate acid,Glutamate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,43.1,2.04,3,6,43.73,1.84,3,6,31.94,1.19,3,6,49.07,0.65,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,32.57,1.549468,6,0.923077,1.188139,-12.819,7.180292,18,2.109816,2.679607,5.653476,-18.4725,-7.16553,Antagonistic
30,874,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glutamate acid,Glutamate acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,43.1,2.04,3,6,41.49,1.08,3,6,31.94,1.19,3,6,45.43,0.52,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,30.33,1.136332,6,0.923077,0.883643,-15.7739,10.70061,18,2.109816,3.271179,6.901584,-22.6754,-8.87228,Antagonistic
30,875,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Serine,Serine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12,1.08,3,6,11.6,0.75,3,6,12.25,1.62,3,6,13.62,1.14,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,11.85,1.262319,6,0.923077,1.202716,-1.35846,0.410226,18,2.109816,0.640489,1.351313,-2.70978,-0.00715,Antagonistic
30,876,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Serine,Serine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12,1.08,3,6,12.04,0.62,3,6,12.25,1.62,3,6,9.09,0.65,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,12.29,1.22654,6,0.923077,0.981555,-3.00935,0.710675,18,2.109816,0.843016,1.778608,-4.78796,-1.23075,Antagonistic
30,877,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Serine,Serine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12,1.08,3,6,11.6,0.75,3,6,8.92,1.6,3,6,12.56,0.58,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.52,1.2495,6,0.923077,0.974076,-3.82848,0.944052,18,2.109816,0.971623,2.049946,-5.87842,-1.77853,Antagonistic
30,878,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Serine,Serine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12,1.08,3,6,12.04,0.62,3,6,8.92,1.6,3,6,12.08,1.04,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.96,1.213342,6,0.923077,1.13,-2.54867,0.603989,18,2.109816,0.777167,1.639679,-4.18835,-0.90899,Antagonistic
30,879,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glycine,Glycine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.31,1.07,3,6,13.55,0.57,3,6,14.2,1.03,3,6,13.38,1.41,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,15.44,0.832406,6,0.923077,1.1578,-1.64237,0.445724,18,2.109816,0.667626,1.408568,-3.05094,-0.2338,Antagonistic
30,880,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glycine,Glycine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.31,1.07,3,6,12.99,1.62,3,6,14.2,1.03,3,6,11.21,0.61,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,14.88,1.357442,6,0.923077,1.052319,-3.21926,0.765153,18,2.109816,0.87473,1.845519,-5.06478,-1.37375,Antagonistic
30,881,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glycine,Glycine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.31,1.07,3,6,13.55,0.57,3,6,12.21,1.93,3,6,9.04,1.99,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,13.45,1.42299,6,0.923077,1.729884,-2.3532,0.564065,18,2.109816,0.751043,1.584562,-3.93776,-0.76864,Antagonistic
30,882,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Glycine,Glycine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.31,1.07,3,6,12.99,1.62,3,6,12.21,1.93,3,6,17.5,2.04,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,12.89,1.781755,6,0.923077,1.915235,2.22186,0.539028,18,2.109816,0.734185,1.548995,0.672865,3.770855,Synergistic
30,883,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Histidine,Histidine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.76,0.5,3,6,10.55,0.74,3,6,8.98,0.62,3,6,10.69,0.89,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.77,0.682642,6,0.923077,0.793127,-2.23458,0.54139,18,2.109816,0.735792,1.552386,-3.78697,-0.6822,Antagonistic
30,884,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Histidine,Histidine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.76,0.5,3,6,8.95,0.65,3,6,8.98,0.62,3,6,6.98,1.1,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,7.17,0.635177,6,0.923077,0.898179,0.195267,0.334922,18,2.109816,0.578725,1.221002,-1.02574,1.416269,Additive
30,885,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Histidine,Histidine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.76,0.5,3,6,10.55,0.74,3,6,7.82,0.61,3,6,9.06,0.62,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,7.61,0.678122,6,0.923077,0.649711,-2.06009,0.510165,18,2.109816,0.714258,1.506953,-3.56704,-0.55313,Antagonistic
30,886,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Histidine,Histidine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.76,0.5,3,6,8.95,0.65,3,6,7.82,0.61,3,6,8.79,0.75,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,6.01,0.630317,6,0.923077,0.692748,-3.70431,0.90508,18,2.109816,0.951357,2.007187,-5.7115,-1.69712,Antagonistic
30,887,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Arginine,Arginine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.72,1.68,3,6,9.57,1.43,3,6,10.67,1.14,3,6,11.41,0.52,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.52,1.293155,6,0.923077,0.985558,-1.77018,0.463897,18,2.109816,0.6811,1.436996,-3.20718,-0.33318,Antagonistic
30,888,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Arginine,Arginine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.72,1.68,3,6,10.19,0.9,3,6,10.67,1.14,3,6,6.04,1.05,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.14,1.027035,6,0.923077,1.038581,3.644026,0.886622,18,2.109816,0.941606,1.986615,1.657411,5.630641,Synergistic
30,889,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Arginine,Arginine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.72,1.68,3,6,9.57,1.43,3,6,7.9,0.62,3,6,9.55,1.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,6.75,1.102112,6,0.923077,1.091112,-2.36879,0.567132,18,2.109816,0.753082,1.588863,-3.95765,-0.77993,Antagonistic
30,890,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Arginine,Arginine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.72,1.68,3,6,10.19,0.9,3,6,7.9,0.62,3,6,10.02,0.62,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,7.37,0.772787,6.00E+00,0.923077,0.700571,-3.49166,0.841319,18,2.109816,0.917235,1.935196,-5.42685,-1.55646,Antagonistic
30,891,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Threonine,Threonine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,6.54,0.35,3,6,6.25,1.51,3,6,5.75,0.63,3,6,7.74,1.78,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,5.46,1.156936,6,0.923077,1.50115,-1.402,0.415234,18,2.109816,0.644386,1.359536,-2.76154,-0.04247,Antagonistic
30,892,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Threonine,Threonine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,6.54,0.35,3,6,6.56,1.6,3,6,5.75,0.63,3,6,5.1,0.82,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,5.77,1.215915,6,0.923077,1.037027,0.596379,0.348153,18,2.109816,0.590045,1.244886,-0.64851,1.841265,Additive
30,893,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Threonine,Threonine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,6.54,0.35,3,6,6.25,1.51,3,6,5,0.62,3,6,6.6,0.61,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,4.71,1.154231,6,0.923077,0.923133,-1.88988,0.482153,18,2.109816,0.694372,1.464997,-3.35488,-0.42489,Antagonistic
30,894,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Threonine,Threonine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,6.54,0.35,3,6,6.56,1.6,3,6,5,0.62,3,6,5.86,1.35,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,5.02,1.213342,6,0.923077,1.283491,-0.60412,0.34854,18,2.109816,0.590373,1.245578,-1.8497,0.641456,Additive
30,895,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Alanine,Alanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,20.11,0.62,3,6,18.23,1.36,3,6,18.83,0.49,3,6,18.07,1.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,16.95,1.022179,6,0.923077,1.051487,-0.98322,0.373614,18,2.109816,0.611239,1.289602,-2.27283,0.30638,Additive
30,896,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Alanine,Alanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,20.11,0.62,3,6,17.05,0.53,3,6,18.83,0.49,3,6,15.19,0.5,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,15.77,0.510392,6,0.923077,0.505223,1.0597,0.380124,18,2.109816,0.616542,1.300789,-0.24109,2.360489,Additive
30,897,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Alanine,Alanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,20.11,0.62,3,6,18.23,1.36,3,6,13.68,0.5,3,6,16.5,0.61,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,11.8,1.024597,6,0.923077,0.843179,-5.14537,1.436449,18,2.109816,1.19852,2.528655,-7.67402,-2.61671,Antagonistic
30,898,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Alanine,Alanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,20.11,0.62,3,6,17.05,0.53,3,6,13.68,0.5,3,6,17.79,0.91,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.62,0.515218,6,0.923077,0.739442,-8.95061,3.671394,18,2.109816,1.916088,4.042593,-12.9932,-4.90802,Antagonistic
30,899,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Proline,Proline,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.72,0.7,3,6,12.09,0.62,3,6,10.41,0.75,3,6,9.42,1.04,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.78,0.688077,6,0.923077,0.881774,0.376863,0.339251,18,2.109816,0.582453,1.228868,-0.852,1.60573,Additive
30,900,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Proline,Proline,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.72,0.7,3,6,11.15,1.62,3,6,10.41,0.75,3,6,9.1,0.62,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.84,1.262319,6,0.923077,0.994447,-0.24134,0.33576,18,2.109816,0.579448,1.222529,-1.46387,0.981189,Additive
30,901,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Proline,Proline,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.72,0.7,3,6,12.09,0.62,3,6,11.16,0.48,3,6,10.34,0.55,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.53,0.554437,6,0.923077,0.552223,0.317598,0.337536,18,2.109816,0.580979,1.225758,-0.90816,1.543355,Additive
30,902,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Proline,Proline,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.72,0.7,3,6,11.15,1.62,3,6,11.16,0.48,3,6,13.26,0.52,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.59,1.194738,6,0.923077,0.921358,-3.67685,0.896634,18,2.109816,0.946908,1.9978,-5.67465,-1.67905,Antagonistic
30,903,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Tyrosine,Tyrosine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.3,0.68,3,6,9.82,0.96,3,6,10.37,1.08,3,6,9.54,0.99,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.89,1.021763,6,0.923077,1.006007,0.321148,0.337631,18,2.109816,0.58106,1.225929,-0.90478,1.547077,Additive
30,904,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Tyrosine,Tyrosine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.3,0.68,3,6,10.17,1.19,3,6,10.37,1.08,3,6,8.26,1.13,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.24,1.136332,6,0.923077,1.13317,1.612902,0.441727,18,2.109816,0.664626,1.402237,0.210664,3.015139,Synergistic
30,905,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Tyrosine,Tyrosine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.3,0.68,3,6,9.82,0.96,3,6,8.32,0.66,3,6,9.31,1.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,7.84,0.823772,6,0.923077,0.960469,-1.41277,0.416497,18,2.109816,0.645366,1.361603,-2.77437,-0.05117,Antagonistic
30,906,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Tyrosine,Tyrosine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,10.3,0.68,3,6,10.17,1.19,3,6,8.32,0.66,3,6,8.85,1.04,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.19,0.962211,6,0.923077,1.001861,-0.6081,0.348741,18,2.109816,0.590543,1.245937,-1.85404,0.637838,Additive
30,907,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Valine,Valine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.81,1.5,3,6,12.53,1.26,3,6,13.92,1.35,3,6,15.85,0.47,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,13.64,1.305776,6,0.923077,0.981313,2.078848,0.5134,18,2.109816,0.71652,1.511724,0.567123,3.590572,Synergistic
30,908,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Valine,Valine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.81,1.5,3,6,12.45,0.49,3,6,13.92,1.35,3,6,9.13,0.61,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,13.56,1.015529,6,0.923077,0.837675,-4.88164,1.326268,18,2.109816,1.151637,2.429742,-7.31138,-2.4519,Antagonistic
30,909,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Valine,Valine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.81,1.5,3,6,12.53,1.26,3,6,9.68,1.23,3,6,14.36,0.66,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.4,1.24509,6,0.923077,0.996456,-4.59474,1.212986,18,2.109816,1.101357,2.323659,-6.9184,-2.27108,Antagonistic
30,910,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Valine,Valine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,12.81,1.5,3,6,12.45,0.49,3,6,9.68,1.23,3,6,13.29,0.55,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.32,0.936216,6,0.923077,0.767789,-4.77295,1.282542,18,2.109816,1.132494,2.389353,-7.1623,-2.38359,Antagonistic
30,911,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Methionine,Methionine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,8.92,0.99,3,6,10.16,0.5,3,6,11.06,1.08,3,6,11,1.5,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,12.3,0.841546,6,0.923077,1.216183,-0.98669,0.373899,18,2.109816,0.611472,1.290094,-2.27679,0.3034,Additive
30,912,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Methionine,Methionine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,8.92,0.99,3,6,8.67,1.24,3,6,11.06,1.08,3,6,6.31,1.06,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.81,1.162755,6,0.923077,1.112565,-3.73358,0.91415,18,2.109816,0.956112,2.01722,-5.7508,-1.71636,Antagonistic
30,913,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Methionine,Methionine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,8.92,0.99,3,6,10.16,0.5,3,6,5.03,1.13,3,6,9.28,0.65,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,6.27,0.873756,6,0.923077,0.770049,-3.60816,0.875785,18,2.109816,0.935834,1.974437,-5.5826,-1.63373,Antagonistic
30,914,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Methionine,Methionine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,8.92,0.99,3,6,8.67,1.24,3,6,5.03,1.13,3,6,11.88,2.7,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,4.78,1.186276,6,0.923077,2.085336,-3.14283,0.74489,18,2.109816,0.86307,1.820918,-4.96374,-1.32191,Antagonistic
30,915,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Cysteine,Cysteine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,1.84,0.61,3,6,1.22,1.09,3,6,2.08,0.5,3,6,1.48,0.77,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.46,0.847968,6,0.923077,0.809923,-0.02279,0.333355,18,2.109816,0.577369,1.218142,-1.24094,1.195348,Additive
30,916,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Cysteine,Cysteine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,1.84,0.61,3,6,1.3,0.5,3,6,2.08,0.5,3,6,1.36,0.49,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,1.54,0.5,6,0.923077,0.495025,0.335647,0.338027,18,2.109816,0.581401,1.226649,-0.891,1.562297,Additive
30,917,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Cysteine,Cysteine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,1.84,0.61,3,6,1.22,1.09,3,6,1.09,0.61,3,6,2.17,0.56,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.47,0.883233,6,0.923077,0.739493,-2.12204,0.52096,18,2.109816,0.721775,1.522813,-3.64485,-0.59922,Antagonistic
30,918,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Cysteine,Cysteine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,1.84,0.61,3,6,1.3,0.5,3,6,1.09,0.61,3,6,1.11,0.7,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,0.55,0.557719,6,0.923077,0.63287,-0.81679,0.361131,18,2.109816,0.600942,1.267877,-2.08467,0.451085,Additive
30,919,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Isoleucine,Isoleucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,9.65,0.75,3,6,10.25,1.56,3,6,10.53,0.86,3,6,11.87,1.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,11.13,1.259603,6,0.923077,1.173243,0.582212,0.347457,18,2.109816,0.589455,1.243641,-0.66143,1.825854,Additive
30,920,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Isoleucine,Isoleucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,9.65,0.75,3,6,7.97,0.62,3,6,10.53,0.86,3,6,5.91,1.6,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,8.85,0.749667,6,0.923077,1.2494,2.17212,0.529921,18,2.109816,0.727957,1.535854,0.636265,3.707974,Synergistic
30,921,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Isoleucine,Isoleucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,9.65,0.75,3,6,10.25,1.56,3,6,11.19,2.09,3,6,10.67,0.52,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,11.79,1.844139,6,0.923077,1.354852,-0.76307,0.357595,18,2.109816,0.597992,1.261653,-2.02472,0.498584,Additive
30,922,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Isoleucine,Isoleucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,9.65,0.75,3,6,7.97,0.62,3,6,11.19,2.09,3,6,9.43,0.9,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.51,1.541509,6,0.923077,1.262191,0.058506,0.333476,18,2.109816,0.577474,1.218363,-1.15986,1.27687,Additive
30,923,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Leucine,Leucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,31.67,0.61,3,6,28.02,1.5,3,6,31.91,1.74,3,6,37.49,1.06,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,28.26,1.624438,6,0.923077,1.371568,-6.21187,1.941137,18,2.109816,1.393247,2.939494,-9.15136,-3.27237,Antagonistic
30,924,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Leucine,Leucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,31.67,0.61,3,6,24.77,1.51,3,6,31.91,1.74,3,6,19.44,1.1,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,25.01,1.629064,6,0.923077,1.389937,3.699116,0.903477,18,2.109816,0.950514,2.00541,1.693706,5.704526,Synergistic
30,925,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Leucine,Leucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,31.67,0.61,3,6,28.02,1.5,3,6,20.44,0.76,3,6,33.48,0.82,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,16.79,1.189033,6,0.923077,1.021323,-15.0845,9.814271,18,2.109816,3.132774,6.609575,-21.6941,-8.47494,Antagonistic
30,926,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Leucine,Leucine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,31.67,0.61,3,6,24.77,1.51,3,6,20.44,0.76,3,6,29.6,1.59,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,13.54,1.195345,6,0.923077,1.406583,-10.5395,4.961671,18,2.109816,2.227481,4.699574,-15.239,-5.83988,Antagonistic
30,927,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Phenylalanine,Phenylalanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,11.76,0.82,3,6,8.01,1.26,3,6,12.94,1.57,3,6,11.09,0.54,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,9.19,1.423464,6,0.923077,1.076534,-1.62916,0.443923,18,2.109816,0.666276,1.405719,-3.03488,-0.22344,Antagonistic
30,928,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Phenylalanine,Phenylalanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,11.76,0.82,3,6,9.56,0.82,3,6,12.94,1.57,3,6,5.3,0.94,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,10.74,1.252458,6,0.923077,1.107305,4.534918,1.190228,18,2.109816,1.090976,2.301758,2.23316,6.836676,Synergistic
30,929,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Phenylalanine,Phenylalanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,11.76,0.82,3,6,8.01,1.26,3,6,7.1,1.05,3,6,10.66,0.69,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,3.35,1.159763,6,0.923077,0.954241,-7.07127,2.416786,18,2.109816,1.554601,3.279922,-10.3512,-3.79135,Antagonistic
30,930,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Phenylalanine,Phenylalanine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,11.76,0.82,3,6,9.56,0.82,3,6,7.1,1.05,3,6,11.93,1.08,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,4.9,0.942046,6,0.923077,1.013373,-6.40359,2.041918,18,2.109816,1.428957,3.014836,-9.41843,-3.38876,Antagonistic
30,931,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Lysine,Lysine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,30.43,1.19,3,6,22.25,0.62,3,6,24.09,0.75,3,6,27.25,1.55,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,15.91,0.688077,6,0.923077,1.199156,-8.72922,3.508301,18,2.109816,1.873046,3.951782,-12.681,-4.77744,Antagonistic
30,932,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Lysine,Lysine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,30.43,1.19,3,6,26.44,1.46,3,6,24.09,0.75,3,6,19.14,1.62,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,20.1,1.160625,6,0.923077,1.409158,0.628854,0.349811,18,2.109816,0.591448,1.247846,-0.61899,1.8767,Additive
30,933,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Lysine,Lysine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,30.43,1.19,3,6,22.25,0.62,3,6,27.54,1.24,3,6,26.24,1.21,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,19.36,0.980306,6,0.923077,1.101158,-5.76735,1.719265,18,2.109816,1.311207,2.766406,-8.53376,-3.00095,Antagonistic
30,934,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Lysine,Lysine,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,30.43,1.19,3,6,26.44,1.46,3,6,27.54,1.24,3,6,25.94,1.25,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,23.55,1.354474,6,0.923077,1.303284,-1.69276,0.452727,18,2.109816,0.67285,1.41959,-3.11235,-0.27318,Antagonistic
30,935,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Total amino acid,Total amino acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,269.39,10.8,3,6,260.27,14.46,3,6,268.78,15.63,3,6,302.18,8.98,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,259.66,15.05637,6,0.923077,12.39626,-3.16621,0.751038,18,2.109816,0.866625,1.828418,-4.99463,-1.3378,Antagonistic
30,936,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Total amino acid,Total amino acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,269.39,10.8,3,6,246,15.29,3,6,268.78,15.63,3,6,190.79,12.68,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,245.39,15.46093,6,0.923077,14.139,3.564607,0.862768,18,2.109816,0.928853,1.959708,1.604899,5.524316,Synergistic
30,937,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Total amino acid,Total amino acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,269.39,10.8,3,6,260.27,14.46,3,6,205.29,10.05,3,6,272.84,11.37,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,196.17,12.45179,6,0.923077,11.92317,-5.9357,1.801354,18,2.109816,1.342145,2.831679,-8.76737,-3.10402,Antagonistic
30,938,Combined polystyrene microplastics and chlorpyrifos decrease levels of nutritional parameters in muscle of rainbow trout (Oncorhynchus mykiss),Organic pollutants,Pesticides,Chlorpyrifos,3,,Total amino acid,Total amino acid,NA,Biochemical,Organic pollutants X Biochemical,N,3,Microg/L,Microg/L,N,4,PS,499,Fragments,N,269.39,10.8,3,6,246,15.29,3,6,205.29,10.05,3,6,274.38,11.07,3,6,N,Hanachi,2021,Oncorhynchus mykiss,Salmonidae,Juvenile,Benthopelagic,181.9,12.93806,6,0.923077,12.04031,-7.09003,2.427854,18,2.109816,1.558157,3.287425,-10.3775,-3.8026,Antagonistic
31,947,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Distance,Total distance moved,cm,Ecological,Organic pollutants X Ecological,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,834.4631,133.3187,3,15,866.087,162.031,3,15,811.3333,121.1154,3,15,908.1737,210.0139,3,15,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,842.9572,143.0437,15,0.972973,179.6766,0.353156,0.135412,45,2.015368,0.367984,0.741622,-0.38847,1.094778,Additive
31,948,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Distance,Total distance moved,cm,Ecological,Organic pollutants X Ecological,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,834.4631,133.3187,3,15,866.087,162.031,3,15,812.1429,134.65,3,15,911.0259,175.2215,3,15,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,843.7668,148.9709,15,0.972973,162.6267,0.402402,0.136032,45,2.015368,0.368825,0.743319,-0.34092,1.145721,Additive
31,957,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,AChE activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,2.696568,0.626747,3,3,1.965887,0.114111,3,3,2.052227,0.50316,3,3,1.429086,0.078218,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,1.321546,0.364823,3,0.8,0.263831,-0.32609,0.675528,9,2.306004,0.821905,1.895316,-2.2214,1.56923,Additive
31,958,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,AChE activity,Acetylcholinesterase expression/activity,U/mgProtein,Metabolic,Organic pollutants X Metabolic,Y,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,2.696568,0.626747,3,3,1.965887,0.114111,3,3,1.898686,0.517933,3,3,1.429086,0.078218,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,1.168005,0.375017,3,0.8,0.270884,-0.77105,0.71621,9,2.306004,0.846292,1.951552,-2.7226,1.180503,Additive
31,967,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Gut-SOD activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,43.6763,24.02627,3,3,36.2234,2.569778,3,3,18.7246,2.065635,3,3,15.81042,3.125865,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,11.2717,2.331374,3,0.8,2.757384,-1.31682,0.811167,9,2.306004,0.900648,2.076899,-3.39372,0.760081,Additive
31,968,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Gut-SOD activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,43.6763,24.02627,3,3,36.2234,2.569778,3,3,8.158792,0.923236,3,3,15.81042,3.125865,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,0.705893,1.930819,3,0.8,2.597989,-4.65114,2.469428,9,2.306004,1.571441,3.62375,-8.27489,-1.02739,Antagonistic
31,977,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Liver-SOD activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,45.71299,8.294425,3,3,58.98235,22.9767,3,3,13.25852,9.778225,3,3,37.11294,5.358779,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,26.52788,17.65704,3,0.8,13.04775,-0.649,0.701767,9,2.306004,0.837715,1.931775,-2.58078,1.282771,Additive
31,978,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Liver-SOD activity,Superoxide dismutase activity/expression,U/mgProtein,Stress response,Organic pollutants X Stress response,Y,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,45.71299,8.294425,3,3,58.98235,22.9767,3,3,15.56916,12.3926,3,3,37.11294,5.358779,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,28.83852,18.45949,3,0.8,13.59171,-0.48703,0.686433,9,2.306004,0.828513,1.910553,-2.39758,1.423526,Additive
31,987,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Gut-CAT activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,111.0021,6.984116,3,3,89.91568,22.31914,3,3,131.4381,12.47035,3,3,98.62456,10.73719,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,110.3517,18.07835,3,0.8,14.86799,0.630999,0.699847,9,2.306004,0.836568,1.92913,-1.29813,2.560129,Additive
31,988,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Gut-CAT activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,111.0021,6.984116,3,3,89.91568,22.31914,3,3,152.9322,9.735503,3,3,98.62456,10.73719,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,131.8457,17.21807,3,0.8,14.34833,-1.85227,0.952574,9,2.306004,0.975999,2.250658,-4.10293,0.398391,Additive
31,997,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Liver-CAT activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,23.87176,4.679474,3,3,70.75728,4.15675,3,3,39.96849,6.591422,3,3,89.31378,2.53129,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,86.85401,5.510237,3,0.8,4.287782,0.458937,0.684219,9,2.306004,0.827175,1.907469,-1.44853,2.366406,Additive
31,998,Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects,Organic pollutants,Pesticides,Chlorpyrifos,3,Day 14,Liver-CAT activity,Catalase activity/expression,U/mgProtein,Metabolic,Organic pollutants X Metabolic,N,3,Micro g/g,ng/L,Y,14,PS,5,Spheres,N,23.87176,4.679474,3,3,70.75728,4.15675,3,3,42.95544,7.009068,3,3,89.31378,2.53129,3,3,N,Huang,2023,Danio rerio,Danionidae,Adult,Benthopelagic,89.84096,5.762187,3,0.8,4.450294,-0.09477,0.667415,9,2.306004,0.816955,1.883901,-1.97867,1.789133,Additive
32,1017,Differential effects of two prevalent environmental pollutants on host-pathogen dynamics,Organic pollutants,Herbicides,Glyphosate,2,Day 72,Worm load,Worm load,Cumulative count,Immunological,Organic pollutants X Immunological,N,2,mg,mg/L,Y,90,PP,300,Fragments,Y,0,0,47,47,0.391304,2.653955,46,46,0,0,37,37,0,0,38,38,N,Masud,2022,Gasterosteus aculeatus,Gasterosteidae,Adult,Benthopelagic,0.391304,1.978141,37,0.989691,1.389144,-0.27878,0.053861,121,1.97993,0.23208,0.459502,-0.73828,0.180718,Additive
32,1036,Differential effects of two prevalent environmental pollutants on host-pathogen dynamics,Organic pollutants,Herbicides,Glyphosate,2,Day 72,Area under curve,Area under curve,Count,Immunological,Organic pollutants X Immunological,N,2,mg,mg/L,Y,109,PP,300,Fragments,Y,0,0,47,47,0,0,46,46,0,0,37,37,0,0,38,38,N,Masud,2022,Gasterosteus aculeatus,Gasterosteidae,Adult,Benthopelagic,0,0,37,0.989691,0,NA,NA,121,1.97993,NA,Undetermined,Undetermined,Undetermined,Synergistic
32,1037,Differential effects of two prevalent environmental pollutants on host-pathogen dynamics,Organic pollutants,Herbicides,Glyphosate,2,,Sum area under curve,Sum area under curve,Count,Immunological,Organic pollutants X Immunological,N,2,mg,mg/L,N,110,PP,300,Fragments,Y,214.6522,293.3467,46,46,271.2174,372.4624,46,46,32,48.51392,36,36,72.52632,112.6138,38,38,N,Masud,2022,Gasterosteus aculeatus,Gasterosteidae,Adult,Benthopelagic,88.56522,281.1838,36,0.989547,212.0168,0.074858,0.054131,120,1.9801,0.232662,0.460693,-0.38583,0.535552,Additive
32,1038,Differential effects of two prevalent environmental pollutants on host-pathogen dynamics,Organic pollutants,Herbicides,Glyphosate,2,,Days infected,Days infected,Count,Immunological,Organic pollutants X Immunological,N,2,mg,mg/L,N,111,PP,300,Fragments,Y,23.65217,9.036266,46,46,26.26087,15.00583,46,46,7.888889,4.327835,36,36,13.89474,13.59608,38,38,N,Masud,2022,Gasterosteus aculeatus,Gasterosteidae,Adult,Benthopelagic,10.49758,11.61272,36,0.989547,12.67079,-0.26531,0.054569,120,1.9801,0.2336,0.462552,-0.72786,0.197246,Additive
33,1047,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,Day 9,Mortality,Mortality,Percent,Ecological,Plastic additives X Ecological,Y,2,ppm,micro g/L,Y,9,PVC,Undisclosed,Undisclosed,Y,5.457,3,6,6,93.309,4.578,6,6,6.69,0.352,6,6,10.211,0.528,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,94.542,3.24669,6,0.923077,2.325917,-33.4681,47.00472,18,2.109816,6.855999,14.46489,-47.933,-19.0032,Antagonistic
33,1048,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,Day 3,Hatching rate,Hatching rate,Percent,Ecological,Plastic additives X Ecological,N,2,ppm,micro g/L,Y,9,PVC,Undisclosed,Undisclosed,Y,53.323,2.568,6,6,0,0,6,6,0,0,6,6,29.456,1.51,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,-53.323,0,6,0.923077,1.067731,-71.5642,213.7267,18,2.109816,14.6194,30.84423,-102.408,-40.72,Antagonistic
33,1054,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,Day 9,Hatching rate,Hatching rate,Percent,Ecological,Plastic additives X Ecological,N,2,ppm,micro g/L,Y,9,PVC,Undisclosed,Undisclosed,Y,94.713,4.531,6,6,33.987,1.511,6,6,71.752,3.323,6,6,86.858,4.229,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,11.026,2.581225,6,0.923077,3.503367,-19.9804,16.96739,18,2.109816,4.119149,8.690645,-28.6711,-11.2898,Antagonistic
33,1055,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Heart rate 24 hpf,Heart rate,bpm,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,91.386,4.303,Undisclosed,5,71.069,3.972,Undisclosed,5,82.86,3.807,Undisclosed,5,98.124,4.64,Undisclosed,5,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,62.543,3.890375,5,0.903226,4.281624,-7.50595,3.216967,15,2.144787,1.793591,3.846869,-11.3528,-3.65908,Antagonistic
33,1056,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Reactive oxygen species,Reactive oxygen species,NA,Stress response,Plastic additives X Stress response,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.169,0,Undisclosed,6,0.278,0,Undisclosed,6,1.263,0,Undisclosed,6,2.855,0,Undisclosed,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,1.372,0,6,0.923077,0,NA,NA,18,2.109816,Inf,Undetermined,Undetermined,Undetermined,Synergistic
33,1058,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Catalase expression,Catalase activity/expression,Relative expression,Metabolic,Plastic additives X Metabolic,Y,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.98,0,6,6,3.165,0,6,6,0.499,0,6,6,1.097,0,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,2.684,0,6,0.923077,0,NA,NA,18,2.109816,Inf,Undetermined,Undetermined,Undetermined,Undetermined
33,1059,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Glutathione peroxidase expression,Glutathione peroxidase activity/expression,Relative expression,Stress response,Plastic additives X Stress response,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.974,0,6,6,7.829,0,6,6,1.062,0,6,6,3.366,0,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,7.917,0,6,0.923077,0,NA,NA,18,2.109816,Inf,Undetermined,Undetermined,Undetermined,Undetermined
33,1060,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Nrf2 expression,Nrf2 expression,Relative expression,Stress response,Plastic additives X Stress response,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.998,0,6,6,1.267,0,6,6,0.846,0,6,6,4.049,0,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,1.115,0,6,0.923077,0,NA,NA,18,2.109816,Inf,Undetermined,Undetermined,Undetermined,Synergistic
33,1061,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Keap1 expression,Keap1 expression,Relative expression,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.992,0,6,6,2.575,0,6,6,4.493,0,6,6,1.193,0,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,6.076,0,6,0.923077,0,NA,NA,18,2.109816,Inf,Undetermined,Undetermined,Undetermined,Undetermined
33,1062,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Bax expression,Bax expression,Relative expression,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,1.014,0.035,6,6,1.295,0.07,6,6,0.323,0.104,6,6,3.285,0.175,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,0.604,0.088645,6,0.923077,0.138714,-17.8408,13.59565,18,2.109816,3.687227,7.77937,-25.6202,-10.0615,Antagonistic
33,1063,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,Bcl2 expression,Bcl2 expression,Relative expression,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,1.031,0.035,6,6,12.979,0.627,6,6,1.211,0.104,6,6,9.084,0.418,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,13.159,0.449414,6,0.923077,0.433991,-8.66732,3.463433,18,2.109816,1.86103,3.92643,-12.5937,-4.74089,Antagonistic
33,1064,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,NKX expression,NKX expression,Relative expression,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,1.001,0.033,6,6,0.325,0.025,6,6,0.325,0.042,6,6,3.479,0.181,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,-0.351,0.034562,6,0.923077,0.130299,-27.1329,31.00815,18,2.109816,5.568496,11.7485,-38.8814,-15.3844,Antagonistic
33,1065,The combined toxic effects of polyvinyl chloride microplastics and di(2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio),Plastic additives,Phthalates,Di(2-ethylhexyl) phthalate,2,,SOX expression,SOX expression,Relative expression,Metabolic,Plastic additives X Metabolic,N,2,ppm,micro g/L,N,9,PVC,Undisclosed,Undisclosed,Y,0.993,0.058,6,6,0.1,0,6,6,0.216,0.026,6,6,5.724,0.276,6,6,Y,Wang,2022,Danio rerio,Danionidae,Juvenile,Benthopelagic,-0.677,0.018385,6,0.923077,0.195594,-30.2086,38.35659,18,2.109816,6.19327,13.06666,-43.2752,-17.1419,Antagonistic
34,1066,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Hepatosomatic index,Hepatosomatic index,NA,Immunological,Plastic additives X Immunological,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,0.492207,0.232516,3,60,0.531204,0.255105,3,60,1.003072,0.534735,3,60,1.01904,0.568861,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,1.042069,0.418939,60,0.993631,0.499556,-0.0458,0.033342,180,1.973305,0.182598,0.360322,-0.40613,0.314518,Additive
34,1067,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Gonadosomatic index,Gonadosomatic index,NA,Ecological,Plastic additives X Ecological,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,6.69795,5.079964,3,60,6.456478,4.576049,3,60,7.566845,7.112235,3,60,7.813855,7.187314,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,7.325373,5.980138,60,0.993631,6.611336,0.073415,0.033356,180,1.973305,0.182636,0.360396,-0.28698,0.433811,Additive
34,1068,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,17?-estradiol,17?-estradiol,pg/ml,Biochemical,Plastic additives X Biochemical,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,463.3471,163.7489,3,60,458.8646,138.3358,3,60,489.336,188.1333,3,60,477.0167,134.4605,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,484.8535,165.1226,60,0.993631,150.574,-0.05171,0.033344,180,1.973305,0.182605,0.360335,-0.41205,0.30862,Additive
34,1069,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Testosterone,Testosterone,pg/ml,Biochemical,Plastic additives X Biochemical,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,166.6064,90.13629,3,60,157.6463,79.80386,3,60,183.2336,82.57617,3,60,209.1491,89.67611,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,174.2735,81.20185,60,0.993631,85.54398,0.405096,0.034017,180,1.973305,0.184437,0.363951,0.041145,0.769047,Synergistic
34,1070,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,17?-estradiol:Testosterone ratio,17?-estradiol:Testosterone ratio,Ratio,Biochemical,Plastic additives X Biochemical,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,4.001892,2.900438,3,60,4.124728,2.921957,3,60,3.583101,2.485985,3,60,2.887952,1.803075,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,3.705937,2.712743,60,0.993631,2.303264,0.352879,0.033852,180,1.973305,0.18399,0.363068,-0.01019,0.715947,Additive
34,1071,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Vitellogenin,Vitellogenin,micro g/ml,Biochemical,Plastic additives X Biochemical,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,19.696,21.01658,3,60,17.91896,18.4695,3,60,10.5115,10.71753,3,60,20.23754,21.44495,3,60,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,8.734457,15.09947,60,0.993631,18.54562,-0.61631,0.034916,180,1.973305,0.186858,0.368728,-0.98504,-0.24758,Antagonistic
34,1092,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,21,Cumulative eggs,Cumulative eggs,Cumulative count,Ecological,Plastic additives X Ecological,N,2,mg/L,micro g/L,Y,21,PS,5.8,Undisclosed,N,848.3333,20.79263,Undisclosed,20,737,15.6205,Undisclosed,20,689,38.62642,Undisclosed,20,523,6.245,Undisclosed,20,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,577.6667,29.46184,20,0.980132,21.29554,2.516047,0.179131,60,2.000995,0.423239,0.846899,1.669148,3.362946,Synergistic
34,1093,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Spawning frequency,Spawning frequency,Count,Ecological,Plastic additives X Ecological,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,17,2,3,20,16.66667,0.57735,3,20,11.33333,0.57735,3,20,9.333333,0.57735,3,20,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,11,0.57735,20,0.980132,0.57735,2.829399,0.200069,60,2.000995,0.44729,0.895026,1.934373,3.724425,Synergistic
34,1094,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Fertilisation,Fertilisation,Count,Ecological,Plastic additives X Ecological,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,86.66667,4.163332,3,20,73,7.211103,3,20,72,8,3,20,65.33333,5.033223,3,20,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,58.33333,7.615773,20,0.980132,6.454972,-1.06289,0.114122,60,2.000995,0.337819,0.675974,-1.73886,-0.38692,Antagonistic
34,1095,Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics,Plastic additives,Plasticisers,Triphenyl phosphate,2,,Hatchability,Hatching rate,Count,Ecological,Plastic additives X Ecological,N,2,mg/L,micro g/L,N,21,PS,5.8,Undisclosed,N,70.66667,5.033223,3,20,71,6.557439,3,20,62.66667,7.571878,3,20,58.66667,3.05505,3,20,N,He,2021,Danio rerio,Danionidae,Adult,Benthopelagic,63,7.082843,20,0.980132,5.454356,0.778688,0.107579,60,2.000995,0.327993,0.656313,0.122375,1.435,Synergistic
35,1096,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Pesticides,Chlorpyrifos,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mg,Metabolic,Organic pollutants X Metabolic,Y,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.497714,0.05683,6,6,0.500726,0.054609,6,6,0.217978,0.111481,6,6,0.202855,0.036761,6,6,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.22099,0.087779,6,0.923077,0.067292,0.248771,0.335912,18,2.109816,0.579579,1.222805,-0.97403,1.471576,Additive
35,1097,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Fungicides,Hexachlorobenzene,2,,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,U/mg,Metabolic,Organic pollutants X Metabolic,Y,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.497714,0.05683,6,6,0.500726,0.054609,6,6,0.496362,0.045215,5,5,0.457917,0.079444,6,6,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.499374,0.050649,5,0.914286,0.068165,-0.55605,0.380721,17,2.119905,0.617026,1.308036,-1.86409,0.751984,Additive
35,1098,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Pesticides,Chlorpyrifos,2,,Glutathione S-transferase activity,Glutathione S-transferase activity,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.591447,0.113029,6,6,0.483247,0.060015,6,6,0.574349,0.095893,6,6,0.556204,0.072261,6,6,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.466148,0.079991,6,0.923077,0.076224,-1.09058,0.38289,18,2.109816,0.618781,1.305513,-2.39609,0.214938,Additive
35,1099,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Fungicides,Hexachlorobenzene,2,,Glutathione S-transferase activity,Glutathione S-transferase activity,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.591447,0.113029,6,6,0.483247,0.060015,6,6,0.414118,0.027615,5,5,0.363093,0.023026,5,5,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.305918,0.048372,5,0.903226,0.037882,-1.36325,0.492922,16,2.13145,0.702084,1.496457,-2.8597,0.133211,Additive
35,1100,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Pesticides,Chlorpyrifos,2,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.008954,0.003623,6,6,0.005901,0.001716,6,6,0.008035,0.002397,6,6,0.010992,0.00324,6,6,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.004982,0.002084,6,0.923077,0.002724,-2.03611,0.506073,18,2.109816,0.711388,1.500897,-3.53701,-0.53521,Antagonistic
35,1101,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Fungicides,Hexachlorobenzene,2,,Alkaline phosphatase activity,Alkaline phosphatase activity,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,0.008954,0.003623,6,6,0.005901,0.001716,6,6,0.006376,0.002431,5,5,0.011369,0.003496,5,5,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,0.003323,0.002064,5,0.903226,0.002871,-2.5314,0.720399,16,2.13145,0.848763,1.809096,-4.3405,-0.7223,Antagonistic
35,1102,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Pesticides,Chlorpyrifos,2,,Catalase activity,Catalase activity/expression,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,9.200876,2.407882,6,6,13.38167,4.796385,6,6,22.78019,2.615894,5,5,25.82415,6.035612,6,6,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,26.96098,3.97769,5,0.914286,5.22208,-0.19904,0.368467,17,2.119905,0.607015,1.286815,-1.48585,1.087777,Additive
35,1103,"Influence of microplastics on the bioconcentration of organic contaminants in fish: Is the ""Trojan horse"" effect a matter of concern?",Organic pollutants,Fungicides,Hexachlorobenzene,2,,Catalase activity,Catalase activity/expression,U/mg,Metabolic,Organic pollutants X Metabolic,N,2,g/L,micro g/L,N,14,PE,150,Fragments,N,9.200876,2.407882,6,6,13.38167,4.796385,6,6,16.90328,5.031047,5,5,22.42508,5.406716,5,5,N,Schell,2022,Danio rerio,Danionidae,Adult,Benthopelagic,21.08408,4.902066,5,0.903226,5.160563,0.234709,0.402754,16,2.13145,0.634629,1.35268,-1.11797,1.58739,Additive
36,1110,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Polycyclic aromatic hydrocarbons,Benzo(k)fluoranthene,3,21,EROD activity,EROD activity,pmol Rescrufin x mg-1 x min-1,Stress response,Organic pollutants X Stress response,N,2,particles/L,micro g/L,Y,21,PMMA,99,Bead,Y,26.5343,8.8448,2,42,16.426,5.0541,2,42,37.9061,7.5813,2,42,46.7509,3.7906,2,42,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,27.7978,6.442827,42,0.990826,5.285767,3.55279,0.122752,126,1.979124,0.35036,0.693405,2.859384,4.246195,Synergistic
36,1111,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Polycyclic aromatic hydrocarbons,Benzo(k)fluoranthene,3,21,EROD activity,EROD activity,pmol Rescrufin x mg-1 x min-1,Stress response,Organic pollutants X Stress response,N,2,particles/L,micro g/L,Y,21,PMMA,99,Bead,Y,26.5343,8.8448,2,42,16.426,5.0541,2,42,221.119,29.062,2,42,26.5343,2.5271,2,42,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,211.0107,20.85838,42,0.990826,14.85695,-12.3029,0.948583,126,1.979124,0.973952,1.927572,-14.2305,-10.3754,Antagonistic
36,1118,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Pesticides,Chlorpyrifos,3,21,EROD activity,EROD activity,pmol Rescrufin x mg-1 x min-1,Stress response,Organic pollutants X Stress response,N,2,mg/L,ng/L,Y,21,PS,Undisclosed,Undisclosed,Y,20.2166,15.1624,2,30,26.5343,8.8448,2,30,136.462,37.906,2,30,17.6895,7.5813,2,30,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,142.7797,27.52358,30,0.987013,20.18692,-6.11612,0.378391,90,1.986979,0.615135,1.22226,-7.33838,-4.89386,Antagonistic
36,1119,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Pesticides,Chlorpyrifos,3,21,EROD activity,EROD activity,pmol Rescrufin x mg-1 x min-1,Stress response,Organic pollutants X Stress response,N,2,mg/L,ng/L,Y,21,PS,Undisclosed,Undisclosed,Y,20.2166,15.1624,2,30,26.5343,8.8448,2,30,45.4874,25.2707,2,30,2.52708,8.84472,2,30,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,51.8051,18.93197,30,0.987013,14.7758,-3.29174,0.156963,90,1.986979,0.396185,0.787212,-4.07895,-2.50453,Antagonistic
36,1126,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Pesticides,Chlorpyrifos,3,21,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,percent,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,ng/L,Y,21,PS,Undisclosed,Undisclosed,Y,82.5,11.6016,2,30,59.2969,9.4531,2,30,54.1406,11.6016,2,30,41.6797,6.875,2,30,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,30.9375,10.58202,30,0.987013,8.923137,-1.18822,0.078432,90,1.986979,0.280058,0.556469,-1.74469,-0.63176,Antagonistic
36,1127,Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene,Organic pollutants,Pesticides,Chlorpyrifos,3,21,Acetylcholinesterase activity,Acetylcholinesterase expression/activity,percent,Metabolic,Organic pollutants X Metabolic,Y,2,mg/L,ng/L,Y,21,PS,Undisclosed,Undisclosed,Y,82.5,11.6016,2,30,59.2969,9.4531,2,30,54.1406,3.4375,2,30,47.2656,10.7422,2,30,Y,Hanslik,2022,Danio rerio,Danionidae,Adult,Benthopelagic,30.9375,7.112577,30,0.987013,9.109984,-1.76905,0.092746,90,1.986979,0.304543,0.60512,-2.37417,-1.16393,Antagonistic